Motif ID: GFI1B.p2

Z-value: 1.138


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1Bchr9_+_134843918-0.194.8e-01Click!


Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_28016182 2.030 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr15_-_81744469 1.932 NM_001717
BNC1
basonuclin 1
chr2_-_189752575 1.699 NM_000393
COL5A2
collagen, type V, alpha 2
chr1_+_216585298 1.664 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr4_+_15080586 1.469 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr6_+_12398514 1.444 NM_001168319
NM_001955
EDN1

endothelin 1

chr3_+_161040343 1.360 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr3_-_64186151 1.244 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr3_-_135231518 1.238 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr7_-_27171673 1.165 NM_152739
HOXA9
homeobox A9
chr7_-_115458010 1.165 NM_001018058
NM_012252
TFEC

transcription factor EC

chr2_-_113259441 1.142 NM_000575
IL1A
interleukin 1, alpha
chr7_-_27171648 1.129 HOXA9
homeobox A9
chr1_+_101475149 1.104 S1PR1
sphingosine-1-phosphate receptor 1
chr7_-_115458064 1.038 TFEC
transcription factor EC
chr6_-_166960690 1.030 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_+_218768423 1.004 MARK1
MAP/microtubule affinity-regulating kinase 1
chr15_+_60146467 0.995 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr6_-_166960649 0.993 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_+_95792299 0.977 NM_000710
BDKRB1
bradykinin receptor B1
chr2_+_176695658 0.967 NM_014213
HOXD9
homeobox D9
chr17_+_7753428 0.948 CHD3
chromodomain helicase DNA binding protein 3
chr11_-_55518675 0.946 NM_003697
OR5F1
olfactory receptor, family 5, subfamily F, member 1
chr11_-_102100833 0.942 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr1_+_161305558 0.932 NM_001113381
RGS4
regulator of G-protein signaling 4
chr14_-_72430545 0.905 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr1_-_197173159 0.897 LOC100131234
familial acute myelogenous leukemia related factor
chr8_-_124613557 0.897 NM_148177
FBXO32
F-box protein 32
chr11_-_85074848 0.831 NM_152723
CCDC89
coiled-coil domain containing 89
chr8_-_114518194 0.800 NM_052900
NM_198123
CSMD3

CUB and Sushi multiple domains 3

chr11_+_111551417 0.766 NM_031938
BCO2
beta-carotene oxygenase 2
chr7_-_113346284 0.759 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr5_+_140241976 0.733 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr7_-_81910956 0.731 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chrX_-_10548458 0.717 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr11_+_19328846 0.704 NM_001111018
NAV2
neuron navigator 2
chr19_-_10489606 0.701 NM_001166215
S1PR5
sphingosine-1-phosphate receptor 5
chr1_+_101474892 0.701 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr3_-_113842255 0.679 CCDC80
coiled-coil domain containing 80
chr6_+_26325124 0.678 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr12_-_113328271 0.660 NM_181486
TBX5
T-box 5
chr3_-_113842350 0.655 CCDC80
coiled-coil domain containing 80
chr8_+_32698892 0.648 NM_001159996
NRG1
neuregulin 1
chr14_-_36121536 0.645 NM_014360
NKX2-8
NK2 homeobox 8
chr7_-_27171600 0.643 HOXA9
homeobox A9
chr4_+_86968069 0.635 ARHGAP24
Rho GTPase activating protein 24
chrX_+_17303727 0.619 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr18_-_43821491 0.612 NM_001039360
ZBTB7C
zinc finger and BTB domain containing 7C
chr5_+_66160359 0.611 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr9_-_106401514 0.601 NM_001004482
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr3_-_113842652 0.599 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr9_-_90983501 0.597 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr1_-_202402043 0.588 NM_000537
REN
renin
chrX_+_147608302 0.584 NM_001170628
AFF2
AF4/FMR2 family, member 2
chr1_+_161305188 0.569 NM_005613
RGS4
regulator of G-protein signaling 4
chr17_+_1566566 0.563 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr3_-_113842553 0.536 CCDC80
coiled-coil domain containing 80
chr1_+_162795538 0.535 PBX1
pre-B-cell leukemia homeobox 1
chr17_-_1566223 0.527 C17orf91
chromosome 17 open reading frame 91
chrX_+_17303458 0.513 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr18_-_33399997 0.507 NM_001025087
NM_001025088
NM_001025089
NM_020180
CELF4



CUGBP, Elav-like family member 4



chr7_+_28441758 0.502 NM_004904
CREB5
cAMP responsive element binding protein 5
chr1_-_188713324 0.493 NM_199051
FAM5C
family with sequence similarity 5, member C
chr4_+_183482130 0.491 NM_001080477
ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr6_-_138862271 0.486 NM_001144060
NHSL1
NHS-like 1
chr1_-_246857051 0.483 NM_001001964
OR2T11
olfactory receptor, family 2, subfamily T, member 11
chr4_+_154345039 0.481 NM_015271
TRIM2
tripartite motif containing 2
chr14_+_20580224 0.479 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chr9_+_136673464 0.476 NM_000093
COL5A1
collagen, type V, alpha 1
chr19_-_14108400 0.471 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr6_-_133076873 0.470 NM_004666
VNN1
vanin 1
chr7_-_16471817 0.469 NM_015464
SOSTDC1
sclerostin domain containing 1
chr1_-_79244948 0.462 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr8_-_93099040 0.461 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_+_12941431 0.454 NM_152654
DAND5
DAN domain family, member 5
chr1_-_17180659 0.453 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr12_-_83954185 0.453 NM_001100917
TSPAN19
tetraspanin 19
chr11_-_35503720 0.452 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr5_+_15553288 0.441 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chrX_+_17303798 0.431 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr12_-_22378833 0.428 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chrX_-_57953578 0.428 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chrX_-_21586337 0.421 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr2_+_176737050 0.418 NM_006898
HOXD3
homeobox D3
chr2_-_142605010 0.416 LRP1B
low density lipoprotein receptor-related protein 1B
chr17_-_34575939 0.414 NM_001143968
ARL5C
ADP-ribosylation factor-like 5C
chr1_+_218768146 0.412 MARK1
MAP/microtubule affinity-regulating kinase 1
chr8_+_67946290 0.410 NM_001136160
C8orf45
chromosome 8 open reading frame 45
chr21_-_46473143 0.405 NM_001001438
NM_001145436
NM_001145437
NM_002340
LSS



lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)



chr6_+_152168500 0.405 NM_001122741
ESR1
estrogen receptor 1
chr4_-_87247829 0.403 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr1_+_27062215 0.401 NM_006142
SFN
stratifin
chr7_-_81910740 0.399 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr8_+_124264054 0.394 FAM83A
family with sequence similarity 83, member A
chr4_+_120167264 0.393 SYNPO2
synaptopodin 2
chr19_+_14108974 0.393


chr11_-_62508946 0.386 NM_004790
NM_153276
NM_153277
NM_153278
SLC22A6



solute carrier family 22 (organic anion transporter), member 6



chr17_+_71232370 0.384 NM_001005619
ITGB4
integrin, beta 4
chr9_-_106407728 0.378 NM_001004481
OR13C2
olfactory receptor, family 13, subfamily C, member 2
chr7_+_18515440 0.373 HDAC9
histone deacetylase 9
chr2_+_238372126 0.363 NM_001080504
RBM44
RNA binding motif protein 44
chr4_+_166097579 0.361 C4orf39
chromosome 4 open reading frame 39
chr9_+_676640 0.360


chr7_+_18515488 0.355 HDAC9
histone deacetylase 9
chr6_-_119137923 0.354 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr17_+_56884560 0.352 TBX4
T-box 4
chrX_+_150653873 0.351 NM_005140
CNGA2
cyclic nucleotide gated channel alpha 2
chr19_+_51492136 0.351 NM_152795
HIF3A
hypoxia inducible factor 3, alpha subunit
chr2_-_113310796 0.342 NM_000576
IL1B
interleukin 1, beta
chr6_+_134251957 0.342 TCF21
transcription factor 21
chrX_+_100692071 0.341 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr1_+_157246305 0.341 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr9_+_108726257 0.338 ZNF462
zinc finger protein 462
chr8_+_32623792 0.338 NM_013959
NRG1
neuregulin 1
chr10_+_118177371 0.336 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr3_-_69064364 0.334 NM_001005527
NM_182522
FAM19A4

family with sequence similarity 19 (chemokine (C-C motif)-like), member A4

chr5_+_140537554 0.328 NM_019120
PCDHB8
protocadherin beta 8
chr3_-_113842237 0.324 CCDC80
coiled-coil domain containing 80
chr11_-_84312085 0.324 NM_001364
DLG2
discs, large homolog 2 (Drosophila)
chr6_-_144370947 0.320 PLAGL1
pleiomorphic adenoma gene-like 1
chr4_-_77147625 0.319 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr11_-_117305277 0.317 NM_001077263
TMPRSS13
transmembrane protease, serine 13
chr4_+_169654742 0.317 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chrX_-_53327473 0.316 NM_015075
IQSEC2
IQ motif and Sec7 domain 2
chr3_-_152449591 0.316 NM_001081455
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr1_+_43539239 0.313 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr6_+_134251940 0.312 NM_198392
NM_003206
TCF21

transcription factor 21

chrX_+_101862297 0.308 NM_001142524
NM_001142525
NM_001142526
NM_001142527
NM_001142528
NM_030639
BHLHB9





basic helix-loop-helix domain containing, class B, 9





chr1_-_68470585 0.304 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr18_+_42780784 0.303 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr11_-_68537243 0.299 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr19_+_45794895 0.295 NM_001042544
LTBP4
latent transforming growth factor beta binding protein 4
chr5_-_146813343 0.294 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr17_+_67628772 0.291 SOX9
SRY (sex determining region Y)-box 9
chr11_+_118269310 0.289 NM_032966
CXCR5
chemokine (C-X-C motif) receptor 5
chr12_-_242255 0.285 NM_001190997
NM_016615
SLC6A13

solute carrier family 6 (neurotransmitter transporter, GABA), member 13

chr9_+_12683385 0.285 NM_000550
TYRP1
tyrosinase-related protein 1
chr5_-_150264583 0.284 ZNF300
zinc finger protein 300
chr9_+_2707525 0.280 NM_133497
KCNV2
potassium channel, subfamily V, member 2
chr15_+_38296920 0.279 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr5_+_102229425 0.277 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr6_+_116939500 0.275 NM_153711
FAM26E
family with sequence similarity 26, member E
chr3_-_152517204 0.274 NM_023915
GPR87
G protein-coupled receptor 87
chr1_+_66570363 0.273 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr12_-_74010071 0.273 NM_032606
CAPS2
calcyphosine 2
chr8_-_18710575 0.272 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr1_-_7998265 0.271 ERRFI1
ERBB receptor feedback inhibitor 1
chr13_-_85271329 0.270 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr14_+_69021149 0.270 NM_001161498
UPF0639
UPF0639 protein
chr18_-_21184824 0.269


chr16_+_55553262 0.268 NM_000078
CETP
cholesteryl ester transfer protein, plasma
chr6_-_152744143 0.268 SYNE1
spectrin repeat containing, nuclear envelope 1
chr14_-_19572756 0.267 NM_001004714
OR4K13
olfactory receptor, family 4, subfamily K, member 13
chr22_+_42726423 0.266 NM_001003828
PARVB
parvin, beta
chr6_-_31756119 0.265 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr5_-_150264622 0.260 ZNF300
zinc finger protein 300
chr18_+_27281729 0.259 NM_001944
DSG3
desmoglein 3
chr19_-_48075572 0.258 NM_001184825
NM_001184826
NM_006905
PSG1


PSG4
pregnancy specific beta-1-glycoprotein 1


pregnancy specific beta-1-glycoprotein 4
chr18_+_19706979 0.258 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr3_-_139333813 0.257 NM_016161
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr3_+_161040439 0.256 SCHIP1
schwannomin interacting protein 1
chr3_+_99555387 0.255 NM_001005517
OR5K4
olfactory receptor, family 5, subfamily K, member 4
chr9_-_21472311 0.254 NM_176891
IFNE
interferon, epsilon
chr12_-_52960168 0.252 NM_012117
CBX5
chromobox homolog 5
chr8_-_68821131 0.252 NM_020361
CPA6
carboxypeptidase A6
chr3_-_192063158 0.247 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr1_+_231007260 0.243 NM_019090
KIAA1383
KIAA1383
chr1_+_209566770 0.242 NM_001033910
TRAF5
TNF receptor-associated factor 5
chr1_+_107485071 0.242 NTNG1
netrin G1
chr19_-_9276794 0.242 NM_198535
ZNF266
ZNF699
zinc finger protein 266
zinc finger protein 699
chr15_+_52092392 0.240 NM_001080534
UNC13C
unc-13 homolog C (C. elegans)
chr17_-_36181927 0.239 NM_181539
KRT26
keratin 26
chr6_+_130799954 0.239 NM_052913
TMEM200A
transmembrane protein 200A
chr2_+_234245243 0.239 NM_021027
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr15_+_100163424 0.235 NM_001005326
OR4F6
olfactory receptor, family 4, subfamily F, member 6
chrX_+_16051344 0.233 NM_005314
GRPR
gastrin-releasing peptide receptor
chr3_-_18455207 0.230 NM_001131010
SATB1
SATB homeobox 1
chr1_-_177378801 0.230 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr1_+_209566789 0.228 TRAF5
TNF receptor-associated factor 5
chr19_+_51190535 0.227 CCDC61
coiled-coil domain containing 61
chr18_+_59295123 0.226 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr12_-_10173947 0.225 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr5_+_140181405 0.224 NM_018908
NM_031501
PCDHA5

protocadherin alpha 5

chr21_-_46473113 0.223 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr12_+_55201854 0.223 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr4_+_110991934 0.223 NM_198506
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chrX_+_17303270 0.218 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr11_-_64284762 0.217 NM_001164716
NM_005609
PYGM

phosphorylase, glycogen, muscle

chr10_-_91001542 0.216 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr9_-_16860719 0.216 NM_017637
BNC2
basonuclin 2
chr19_-_14108267 0.216 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr4_-_88669267 0.216 SPARCL1
SPARC-like 1 (hevin)
chr4_-_82345224 0.215 NM_006259
PRKG2
protein kinase, cGMP-dependent, type II
chr2_-_164300758 0.214 NM_018086
FIGN
fidgetin
chr6_+_53991672 0.214 NM_138569
C6orf142
chromosome 6 open reading frame 142
chr4_-_189263395 0.214 NM_173553
TRIML2
tripartite motif family-like 2
chr3_-_168674502 0.214 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr11_-_4747722 0.212 NM_001004752
OR51F1
olfactory receptor, family 51, subfamily F, member 1
chr17_+_67628763 0.212 SOX9
SRY (sex determining region Y)-box 9
chr11_+_111552298 0.212 NM_001037290
BCO2
beta-carotene oxygenase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.40 2.29e-05 GO:0032501 multicellular organismal process
2.04 3.86e-03 GO:0009888 tissue development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.62 3.09e-04 GO:0005576 extracellular region
1.36 2.71e-03 GO:0005886 plasma membrane
1.82 3.71e-03 GO:0044421 extracellular region part
1.34 6.18e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.53 8.39e-03 GO:0004871 signal transducer activity
1.53 8.39e-03 GO:0060089 molecular transducer activity
1.88 1.20e-02 GO:0004930 G-protein coupled receptor activity
1.54 4.19e-02 GO:0004872 receptor activity