Motif ID: HLF.p2

Z-value: 1.315


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
HLF 3131 hepatic leukemia factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HLFchr17_+_506999650.792.4e-04Click!


Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_113601608 2.863 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr2_+_113601616 1.820 IL1RN
interleukin 1 receptor antagonist
chr10_-_52315436 1.509 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr1_-_62557655 1.450 NM_181712
KANK4
KN motif and ankyrin repeat domains 4
chr16_+_70646008 1.364 NM_001126102
NM_005143
HP

haptoglobin

chr6_-_50045296 1.352 NM_001037729
DEFB113
defensin, beta 113
chr1_-_228916486 1.344 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr8_+_124263932 1.234 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr20_+_16676997 1.233 NM_020157
OTOR
otoraplin
chr4_+_187424336 1.223 F11
coagulation factor XI
chr3_+_187917791 1.138 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr8_+_124264054 1.086 FAM83A
family with sequence similarity 83, member A
chr1_-_228916470 1.074 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr9_+_116125123 1.052 NM_000607
ORM1
orosomucoid 1
chr9_-_70780574 1.044


chr11_-_4675524 1.033 NM_030774
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr10_-_82039158 0.942 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr1_-_62557559 0.937 KANK4
KN motif and ankyrin repeat domains 4
chr3_-_12561962 0.937 NM_001195279
LOC100129480
hypothetical protein LOC100129480
chr1_-_228916559 0.920 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr19_+_40541327 0.900 NM_005304
FFAR3
free fatty acid receptor 3
chr2_+_64540843 0.899 HSPC159
galectin-related protein
chr19_-_6410735 0.876 NM_024103
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr16_+_55963899 0.848 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr3_+_46591048 0.847 NM_001174136
TDGF1
teratocarcinoma-derived growth factor 1
chr20_+_58064360 0.834 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr6_-_30188845 0.817 NM_007028
TRIM31
tripartite motif containing 31
chr19_-_46048033 0.808 NM_000762
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr2_-_98646367 0.805 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr3_-_121883647 0.804 HGD
homogentisate 1,2-dioxygenase
chr2_+_108360798 0.794 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr14_-_20694023 0.780 NM_001004731
OR5AU1
olfactory receptor, family 5, subfamily AU, member 1
chr11_-_14950366 0.777 NM_001033952
NM_001033953
NM_001741
CALCA


calcitonin-related polypeptide alpha


chr9_+_110664366 0.776 NM_006687
ACTL7A
actin-like 7A
chr19_-_56147971 0.776 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr3_+_187813538 0.761 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr11_-_102081654 0.744 NM_022122
MMP27
matrix metallopeptidase 27
chr3_+_120984246 0.736 NM_022002
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr1_+_115373937 0.728 NM_000549
TSHB
thyroid stimulating hormone, beta
chr10_-_95350949 0.722 NM_006744
RBP4
retinol binding protein 4, plasma
chr17_+_39280041 0.716 NM_001168322
NM_001168323
NM_001168324
NM_145273
CD300LG



CD300 molecule-like family member g



chr4_+_100704262 0.713 NM_000253
MTTP
microsomal triglyceride transfer protein
chr1_+_151081953 0.680 NM_001128600
LCE6A
late cornified envelope 6A
chr22_+_49272078 0.676 NM_017584
MIOX
myo-inositol oxygenase
chr8_-_27524744 0.675 NM_203339
CLU
clusterin
chr8_-_145187553 0.669 NM_017570
OPLAH
5-oxoprolinase (ATP-hydrolysing)
chr1_+_149221122 0.643 NM_003568
ANXA9
annexin A9
chr16_+_70654625 0.636 NM_020995
HPR
haptoglobin-related protein
chr19_-_40684638 0.626 NM_001035516
DMKN
dermokine
chr7_+_143511480 0.621 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr7_+_129634935 0.618 NM_145268
C7orf45
chromosome 7 open reading frame 45
chr20_+_4614796 0.610 NM_000311
NM_001080121
NM_001080122
NM_183079
NM_001080123
PRNP




prion protein




chr11_-_116168316 0.601 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr11_+_76516957 0.598 NM_000260
NM_001127179
NM_001127180
MYO7A


myosin VIIA


chr17_-_31548167 0.592 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr3_+_187813553 0.588 AHSG
alpha-2-HS-glycoprotein
chr6_-_24491498 0.583 NM_001195610
DCDC2
doublecortin domain containing 2
chr3_+_187866464 0.582 NM_000412
HRG
histidine-rich glycoprotein
chr17_+_31562577 0.581 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr1_+_205328834 0.580 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr6_-_132073849 0.579 NM_001145659
CTAGE9
CTAGE family, member 9
chr17_-_38978772 0.576 NM_001986
ETV4
ets variant 4
chr10_-_116434364 0.564 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr17_-_31352643 0.556 CCL14-CCL15
CCL15
CCL14-CCL15 read-through transcript
chemokine (C-C motif) ligand 15
chr19_-_411995 0.551 NM_012435
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr2_+_65517316 0.542 FLJ16124
FLJ16124 protein
chr17_+_72047709 0.538 NM_001077620
PRCD
progressive rod-cone degeneration
chr10_+_70650064 0.537 NM_025130
HKDC1
hexokinase domain containing 1
chr19_-_46080496 0.535 NM_000764
NM_030589
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr17_-_15311649 0.534 NM_173622
CDRT4
CMT1A duplicated region transcript 4
chr17_-_31352720 0.530 CCL14-CCL15
CCL14-CCL15 read-through transcript
chr2_+_113542017 0.530 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chr14_+_23633101 0.512 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr3_-_172227152 0.510 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr11_+_113280727 0.510 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr21_-_30836051 0.501 NM_181612
KRTAP19-6
keratin associated protein 19-6
chr21_-_31041390 0.496 NM_181617
KRTAP21-2
keratin associated protein 21-2
chr6_+_32003180 0.494 NM_000063
NM_001145903
C2

complement component 2

chr20_+_29492071 0.494 NM_153324
DEFB123
defensin, beta 123
chr13_-_45577144 0.493 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr2_+_69995740 0.492 MXD1
MAX dimerization protein 1
chr20_+_61967078 0.492 TPD52L2
tumor protein D52-like 2
chr4_+_71096830 0.486 NM_017855
ODAM
odontogenic, ameloblast asssociated
chrX_+_65152004 0.484


chr7_-_143597313 0.475 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr16_+_66614645 0.474 NM_017803
DUS2L
dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr16_-_54424517 0.470 NM_001025194
NM_001025195
NM_001266
CES1


carboxylesterase 1


chr7_-_111216180 0.469 DOCK4
dedicator of cytokinesis 4
chr20_+_61967094 0.465 TPD52L2
tumor protein D52-like 2
chrX_-_134883500 0.464 MMGT1
membrane magnesium transporter 1
chr9_+_102987137 0.457 NM_017753
LPPR1
lipid phosphate phosphatase-related protein type 1
chr6_+_32003380 0.449 C2
complement component 2
chr17_+_49255237 0.436 NM_032559
KIF2B
kinesin family member 2B
chr7_+_34664342 0.436 NM_207172
NM_207173
NPSR1

neuropeptide S receptor 1

chr12_-_1791146 0.432 CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr10_+_18669619 0.430 NM_201590
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_-_32047637 0.428 DOM3Z
dom-3 homolog Z (C. elegans)
chr20_+_61967122 0.424 TPD52L2
tumor protein D52-like 2
chr16_-_54424473 0.422 CES1
carboxylesterase 1
chr17_-_36346240 0.418 KRT23
keratin 23 (histone deacetylase inducible)
chr3_-_47932479 0.418


chr11_+_93394025 0.414 NM_001098672
HEPHL1
hephaestin-like 1
chr3_+_134976965 0.411 TF
transferrin
chrX_+_100111352 0.408 NM_001012990
NM_001162490
NM_001162491
ARL13A


ADP-ribosylation factor-like 13A


chr17_-_70131389 0.404 NM_181449
CD300E
CD300e molecule
chr21_-_43671355 0.398 NM_173354
SIK1
salt-inducible kinase 1
chrX_+_41191630 0.397 NM_022567
NYX
nyctalopin
chr5_+_126140213 0.393 NM_005573
LMNB1
lamin B1
chr12_-_10497195 0.391 NM_002259
NM_007328
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr16_+_29942155 0.390 NM_001109659
NM_001109660
C16orf92

chromosome 16 open reading frame 92

chr1_+_152644471 0.386 IL6R
interleukin 6 receptor
chr4_+_71418886 0.386 NM_212557
AMTN
amelotin
chr20_+_61967033 0.383 NM_003288
NM_199359
NM_199360
NM_199361
NM_199362
NM_199363
TPD52L2





tumor protein D52-like 2





chr17_+_65612589 0.380 NM_170742
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_-_143085704 0.380 NM_178561
CTAGE6P
CTAGE family, member 6, pseudogene
chr17_-_71352017 0.376 UNC13D
unc-13 homolog D (C. elegans)
chr9_+_116131889 0.375 NM_000608
ORM2
orosomucoid 2
chr11_-_28086263 0.372 KIF18A
kinesin family member 18A
chr2_+_201464884 0.368 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr3_+_143824955 0.363 NM_002670
PLS1
plastin 1
chr9_-_106705867 0.362 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr14_+_20493467 0.361 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr12_-_28016182 0.359 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr22_+_33792125 0.354 NM_001008494
ISX
intestine-specific homeobox
chr3_-_49701085 0.352 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr9_-_103237851 0.350 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr6_+_20642665 0.348 NM_017774
CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
chr17_-_53849929 0.346 NM_017763
RNF43
ring finger protein 43
chr1_+_227506751 0.345 NM_006542
SPHAR
S-phase response (cyclin related)
chr19_-_50779914 0.344 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr1_+_11171967 0.343 NM_021146
ANGPTL7
angiopoietin-like 7
chr10_-_116434102 0.340 ABLIM1
actin binding LIM protein 1
chr6_+_131936057 0.340 NM_000045
ARG1
arginase, liver
chr9_+_71009746 0.339 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr3_-_172227223 0.338 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr2_+_69995807 0.338 MXD1
MAX dimerization protein 1
chr5_+_150612805 0.335 NM_000405
NM_001167607
GM2A

GM2 ganglioside activator

chr1_-_205210567 0.335 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr20_+_2030527 0.334 NM_080836
STK35
serine/threonine kinase 35
chr17_-_53849888 0.333 RNF43
ring finger protein 43
chr21_-_42060266 0.332 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr1_-_228916958 0.331 NM_000029
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr9_-_69729926 0.329 CBWD5
CBWD3
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 6
chr20_+_41621119 0.329 SGK2
serum/glucocorticoid regulated kinase 2
chr2_+_219453487 0.327 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr17_-_75427644 0.326 NM_003655
CBX4
chromobox homolog 4
chr4_+_77214886 0.323 NM_001130016
NM_001179
ART3

ADP-ribosyltransferase 3

chr14_+_20568184 0.322 NM_173846
TPPP2
tubulin polymerization-promoting protein family member 2
chr14_+_20429382 0.318 NM_002935
RNASE2
RNASE3
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
ribonuclease, RNase A family, 3
chr22_-_27787793 0.318 NM_015370
C22orf31
chromosome 22 open reading frame 31
chr6_-_24597717 0.313 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr20_+_31613800 0.309 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr16_+_9093035 0.309 NM_014117
C16orf72
chromosome 16 open reading frame 72
chr7_-_129379947 0.307 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr8_-_6722848 0.307 NM_005218
DEFB1
defensin, beta 1
chr17_-_61655915 0.305 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr19_-_4491078 0.303 LRG1
leucine-rich alpha-2-glycoprotein 1
chr14_-_19871267 0.301 NM_021178
NM_182849
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr7_+_55987046 0.301 NM_015969
MRPS17
mitochondrial ribosomal protein S17
chr4_-_110942783 0.299 NM_000204
CFI
complement factor I
chr1_+_150005754 0.293 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr10_+_89257569 0.288 NM_001178118
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr3_-_58175437 0.285 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr20_+_41621079 0.285 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr3_+_187813405 0.282 AHSG
alpha-2-HS-glycoprotein
chr2_+_232165818 0.280 NM_152614
C2orf57
chromosome 2 open reading frame 57
chr18_+_54039779 0.278 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr4_+_119174947 0.278 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr17_-_38530935 0.276 NM_007297
NM_007299
NM_007294
NM_007300
BRCA1



breast cancer 1, early onset



chr5_+_147695314 0.275 NM_001040433
SPINK9
serine peptidase inhibitor, Kazal type 9
chr14_-_21172837 0.274 NM_001005466
OR10G2
olfactory receptor, family 10, subfamily G, member 2
chr4_+_155703581 0.271 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chrX_-_13744933 0.268 GPM6B
glycoprotein M6B
chr9_-_68552337 0.267 NM_001085457
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr2_-_31491057 0.266 XDH
xanthine dehydrogenase
chr8_+_21972804 0.263 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr14_+_95740916 0.263 BDKRB2
bradykinin receptor B2
chr8_-_86441115 0.262 NM_001164830
CA1
carbonic anhydrase I
chr6_+_26312758 0.259 NM_003545
HIST1H4E
histone cluster 1, H4e
chr2_+_190710730 0.259 NM_001042521
C2orf88
chromosome 2 open reading frame 88
chr6_-_132987106 0.258 NM_001033080
TAAR2
trace amine associated receptor 2
chr19_-_55833113 0.258 NM_032298
SYT3
synaptotagmin III
chr17_+_38575939 0.256 NM_031862
NM_031858
NBR1

neighbor of BRCA1 gene 1

chr6_-_119512035 0.256 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr2_+_169634330 0.255 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_-_100416358 0.255 NM_144620
LRRC39
leucine rich repeat containing 39
chr5_+_175241449 0.255 CPLX2
complexin 2
chr7_+_89870707 0.254 CLDN12
claudin 12
chr2_+_101974737 0.254 NM_004633
IL1R2
interleukin 1 receptor, type II
chr2_+_183697327 0.253 NM_138285
NUP35
nucleoporin 35kDa
chr7_+_142978994 0.252 NM_001008747
CTAGE6P
CTAGE15P
CTAGE family, member 6, pseudogene
CTAGE family, member 15, pseudogene
chr18_-_41932255 0.252 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr17_-_46479127 0.250 SPAG9
sperm associated antigen 9
chr17_-_31353196 0.250 NM_032965
CCL15
chemokine (C-C motif) ligand 15
chr20_-_48980858 0.250 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr9_-_129752687 0.249 NM_203305
FAM102A
family with sequence similarity 102, member A
chr10_-_101180191 0.248 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr2_-_43676603 0.247 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr19_+_50663089 0.246 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr10_+_114123765 0.246 ACSL5
acyl-CoA synthetase long-chain family member 5

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.90 3.91e-04 GO:0005615 extracellular space
1.65 8.48e-03 GO:0044421 extracellular region part
1.39 4.39e-02 GO:0005576 extracellular region

Nothing significant found in function category.