Motif ID: KLF12.p2

Z-value: 3.947


Transcription factors associated with KLF12.p2:

Gene SymbolEntrez IDGene Name
KLF12 11278 Kruppel-like factor 12

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF12chr13_-_736063620.439.5e-02Click!


Activity profile for motif KLF12.p2.

activity profile for motif KLF12.p2


Sorted Z-values histogram for motif KLF12.p2

Sorted Z-values for motif KLF12.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF12.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_45620911 5.322 COL1A1
collagen, type I, alpha 1
chr9_+_136673534 3.830 COL5A1
collagen, type V, alpha 1
chr9_+_136673464 3.191 NM_000093
COL5A1
collagen, type V, alpha 1
chr19_-_19487237 2.622 NM_032037
TSSK6
testis-specific serine kinase 6
chr1_-_53380709 2.560 NM_006671
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr16_-_30992574 2.346 ZNF668
zinc finger protein 668
chr2_-_220144254 2.322 OBSL1
obscurin-like 1
chr11_+_66381451 2.303 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_+_1256585 2.292 NM_152228
TAS1R3
taste receptor, type 1, member 3
chr1_-_201321711 2.229 MYOG
myogenin (myogenic factor 4)
chr11_-_65841077 2.226 NM_020404
CD248
CD248 molecule, endosialin
chr8_+_37672427 2.211 NM_025069
ZNF703
zinc finger protein 703
chr17_+_45617676 2.199


chr2_+_85834111 2.155 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr17_+_23723180 2.068 SARM1
sterile alpha and TIR motif containing 1
chr17_+_39990124 2.059 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr1_+_23990228 2.052 NM_007260
LYPLA2
lysophospholipase II
chr16_-_66535457 2.042 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr3_-_130761967 2.033 PLXND1
plexin D1
chr11_+_65164963 2.003


chrX_+_67965517 2.000 NM_004429
EFNB1
ephrin-B1
chr8_-_20156971 1.969 NM_021020
LZTS1
leucine zipper, putative tumor suppressor 1
chr17_-_76064842 1.911 NM_002522
NPTX1
neuronal pentraxin I
chr15_-_88148177 1.884 ANPEP
alanyl (membrane) aminopeptidase
chr11_-_65860450 1.844 NM_004292
RIN1
Ras and Rab interactor 1
chr15_+_65904994 1.809 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr19_+_43572679 1.778 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chr20_-_2769120 1.763 FAM113A
family with sequence similarity 113, member A
chr1_+_168899936 1.744 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr1_+_162795538 1.742 PBX1
pre-B-cell leukemia homeobox 1
chr17_-_1342700 1.734 NM_001080779
MYO1C
myosin IC
chr17_-_36807322 1.699 NM_002277
KRT31
keratin 31
chr1_+_151015471 1.688 NM_178354
LCE1F
late cornified envelope 1F
chr20_+_61394982 1.660 NM_020882
COL20A1
collagen, type XX, alpha 1
chr20_-_2769245 1.651 NM_022760
FAM113A
family with sequence similarity 113, member A
chr4_+_2783764 1.649 SH3BP2
SH3-domain binding protein 2
chr5_-_168660293 1.615 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr5_+_133870175 1.604


chr9_-_116920232 1.580 NM_002160
TNC
tenascin C
chr2_+_234209838 1.564 NM_019075
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr4_+_72321113 1.560 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr5_-_149515331 1.550 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr12_+_46133 1.549 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr16_-_30993004 1.529 NM_024706
ZNF668
zinc finger protein 668
chr3_+_50281309 1.517 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr2_+_220017617 1.476 SPEG
SPEG complex locus
chr1_-_33613729 1.474 NM_198040
PHC2
polyhomeotic homolog 2 (Drosophila)
chr11_+_118259684 1.470 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr1_-_201321999 1.466 NM_002479
MYOG
myogenin (myogenic factor 4)
chr15_-_38953628 1.455 NM_133639
RHOV
ras homolog gene family, member V
chr22_-_37598115 1.437 CBX6
chromobox homolog 6
chr2_-_220116508 1.431 NM_024536
CHPF
chondroitin polymerizing factor
chr5_+_60663842 1.413 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr17_-_36451189 1.410 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr11_-_118471313 1.401 H2AFX
H2A histone family, member X
chr19_-_60566419 1.400 NM_001145402
FAM71E2
family with sequence similarity 71, member E2
chr1_+_53300410 1.391 NM_153703
PODN
podocan
chr12_+_6768866 1.390 NM_000616
CD4
CD4 molecule
chr17_-_1495742 1.385 NM_003693
NM_145350
NM_145352
SCARF1


scavenger receptor class F, member 1


chr1_-_238842011 1.371 GREM2
gremlin 2
chr22_+_18499354 1.363 NM_001185024
NM_013373
ZDHHC8

zinc finger, DHHC-type containing 8

chr7_+_99919485 1.362 NM_173564
C7orf51
chromosome 7 open reading frame 51
chr8_-_145132582 1.360 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chr5_+_159276317 1.359 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr17_+_23722689 1.348 SARM1
sterile alpha and TIR motif containing 1
chr17_-_36418869 1.346 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr17_+_77925441 1.343 NM_018949
UTS2R
urotensin 2 receptor
chr22_-_29052863 1.330 NM_031937
TBC1D10A
TBC1 domain family, member 10A
chr1_+_199108705 1.323 NM_005298
GPR25
G protein-coupled receptor 25
chr11_+_65164767 1.319 SIPA1
signal-induced proliferation-associated 1
chr9_-_90983501 1.316 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr17_+_67628749 1.314 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr19_-_51081147 1.301 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr19_+_55045754 1.297 PTOV1
prostate tumor overexpressed 1
chr17_+_74542066 1.296 NM_198593
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr1_+_25816545 1.280 NM_020379
MAN1C1
mannosidase, alpha, class 1C, member 1
chr3_-_193609531 1.280 NM_021032
FGF12
fibroblast growth factor 12
chr22_+_29817218 1.270 SMTN
smoothelin
chr19_+_50963484 1.259


chr4_+_30331289 1.258 PCDH7
protocadherin 7
chr19_+_47521600 1.251 NM_001410
MEGF8
multiple EGF-like-domains 8
chr5_-_50714836 1.234 LOC642366
hypothetical LOC642366
chr4_-_87989291 1.223 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr5_+_140762551 1.223 NM_018921
NM_032089
PCDHGA9

protocadherin gamma subfamily A, 9

chr15_+_71763674 1.222 NM_001024736
NM_025240
CD276

CD276 molecule

chr11_-_118471385 1.221 NM_002105
H2AFX
H2A histone family, member X
chr1_+_26220895 1.221 EXTL1
exostoses (multiple)-like 1
chrX_+_49013424 1.211 PPP1R3F
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr4_-_14613030 1.211 LOC441009
hypothetical protein LOC441009
chr10_+_104394185 1.203 NM_030912
TRIM8
tripartite motif containing 8
chr19_+_5865192 1.200 NM_004058
NM_080590
CAPS

calcyphosine

chr16_-_1954827 1.195 NM_002952
RPS2
ribosomal protein S2
chr7_-_96492064 1.188 NM_005221
DLX5
distal-less homeobox 5
chr1_+_1157485 1.180 NM_080605
B3GALT6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr12_-_49878216 1.175 NM_002702
POU6F1
POU class 6 homeobox 1
chr20_+_31268779 1.172 NM_001042439
NM_178466
C20orf71

chromosome 20 open reading frame 71

chr9_-_90983195 1.171 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr15_+_75074483 1.170 NM_003978
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr10_+_88404285 1.168 NM_001030015
NM_033282
OPN4

opsin 4

chr22_+_29817315 1.166 SMTN
smoothelin
chr15_+_72005864 1.164 LOXL1
lysyl oxidase-like 1
chr5_+_140790141 1.163 PCDHGA12
protocadherin gamma subfamily A, 12
chr19_-_50963942 1.155


chr9_-_113130533 1.151 NM_205859
OR2K2
olfactory receptor, family 2, subfamily K, member 2
chr20_+_2769338 1.149 NM_022575
NM_080413
VPS16

vacuolar protein sorting 16 homolog (S. cerevisiae)

chr17_-_35331435 1.148 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr2_+_219453487 1.143 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr15_-_63147228 1.136 RASL12
RAS-like, family 12
chr17_-_38081967 1.135 NM_024927
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr19_+_60679510 1.125 NM_033113
ZNF628
zinc finger protein 628
chr22_-_37598160 1.118 CBX6
chromobox homolog 6
chr7_+_27190688 1.110


chr6_-_34324739 1.109 C6orf1
chromosome 6 open reading frame 1
chr10_-_105604942 1.108 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr5_+_140790510 1.103 PCDHGA12
protocadherin gamma subfamily A, 12
chr15_-_72446979 1.103 NM_000781
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr19_+_2427122 1.101 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr11_-_1464386 1.099 NM_001172223
MOB2
Mps one binder kinase activator-like 2
chr9_+_134447795 1.095 NM_020064
BARHL1
BarH-like homeobox 1
chr5_+_140790310 1.091 NM_003735
NM_032094
PCDHGA12

protocadherin gamma subfamily A, 12

chr6_-_152744022 1.091 SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_+_140698537 1.088 NM_018915
NM_032009
PCDHGA2

protocadherin gamma subfamily A, 2

chr12_-_51861388 1.087 CSAD
cysteine sulfinic acid decarboxylase
chr1_-_68470585 1.087 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr15_-_63147350 1.085 NM_016563
RASL12
RAS-like, family 12
chr17_+_7549138 1.084 NM_001406
EFNB3
ephrin-B3
chr19_-_55072263 1.081 NM_032375
NM_001098633
NM_001098632
AKT1S1


AKT1 substrate 1 (proline-rich)


chr7_+_27248688 1.071 NM_001989
EVX1
even-skipped homeobox 1
chr16_-_30992323 1.070 NM_001172668
ZNF668
zinc finger protein 668
chr15_+_72005875 1.067 LOXL1
lysyl oxidase-like 1
chr10_-_105410840 1.060


chr9_+_110664366 1.056 NM_006687
ACTL7A
actin-like 7A
chr16_-_2099854 1.056 PKD1
polycystic kidney disease 1 (autosomal dominant)
chr10_-_81698840 1.054 NM_003019
SFTPD
surfactant protein D
chr20_-_604822 1.054 NM_033129
SCRT2
scratch homolog 2, zinc finger protein (Drosophila)
chr19_+_16296734 1.047 KLF2
Kruppel-like factor 2 (lung)
chr2_+_220015016 1.041 SPEG
SPEG complex locus
chr11_+_46323495 1.040 DGKZ
diacylglycerol kinase, zeta
chr20_+_34603311 1.040 MYL9
myosin, light chain 9, regulatory
chr20_-_2769789 1.037 FAM113A
family with sequence similarity 113, member A
chrX_-_47364173 1.036 NM_006950
NM_133499
SYN1

synapsin I

chr11_+_5925152 1.034 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr12_-_79855618 1.031 NM_004664
LIN7A
lin-7 homolog A (C. elegans)
chr7_+_75947762 1.029 NM_001102596
DTX2
deltex homolog 2 (Drosophila)
chr7_+_100111712 1.028 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr2_-_228754585 1.023 NM_001142644
NM_030623
SPHKAP

SPHK1 interactor, AKAP domain containing

chr17_-_17816425 1.023 NM_001033551
NM_001082968
TOM1L2

target of myb1-like 2 (chicken)

chr20_-_62181588 1.020 NM_001039467
RGS19
regulator of G-protein signaling 19
chr12_+_6930778 1.015 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr19_+_2173415 1.014 DOT1L
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr1_-_238842071 1.011 NM_022469
GREM2
gremlin 2
chr22_+_35777561 1.007 NM_024681
KCTD17
potassium channel tetramerisation domain containing 17
chr3_+_42670179 1.006 NM_145166
ZBTB47
zinc finger and BTB domain containing 47
chr9_+_115970599 1.006 COL27A1
collagen, type XXVII, alpha 1
chr4_+_7245218 1.006 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr17_+_23723220 1.005 SARM1
sterile alpha and TIR motif containing 1
chr5_+_140790365 1.002 PCDHGA12
protocadherin gamma subfamily A, 12
chr7_-_5427367 1.001


chr10_+_124310170 0.992 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr11_+_6847499 0.991 NM_001004460
OR10A2
olfactory receptor, family 10, subfamily A, member 2
chr2_+_241279934 0.988 NM_198998
AQP12A
AQP12B
aquaporin 12A
aquaporin 12B
chr16_+_2503915 0.984 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr9_+_35528890 0.981 RUSC2
RUN and SH3 domain containing 2
chr16_+_30583599 0.972 FBRS
fibrosin
chr11_-_1599900 0.969 NM_001012709
KRTAP5-4
keratin associated protein 5-4
chr7_-_117300763 0.966 NM_033427
CTTNBP2
cortactin binding protein 2
chr5_+_140709907 0.964 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr1_-_36562341 0.963 NM_018166
FAM176B
family with sequence similarity 176, member B
chrX_-_53367246 0.961 NM_001111125
IQSEC2
IQ motif and Sec7 domain 2
chr9_+_115303527 0.960 NM_130795
RGS3
regulator of G-protein signaling 3
chr12_+_52653176 0.960 NM_014212
HOXC11
homeobox C11
chr21_-_46428788 0.958 NM_001142854
NM_032261
C21orf56

chromosome 21 open reading frame 56

chr20_+_19818209 0.958 NM_018993
RIN2
Ras and Rab interactor 2
chrX_-_106033202 0.955 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr3_+_50281582 0.953 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr2_-_128138435 0.952 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr16_-_65510230 0.952 NM_004062
CDH16
cadherin 16, KSP-cadherin
chr20_+_42007949 0.951 NM_001098798
TOX2
TOX high mobility group box family member 2
chr17_-_34607257 0.946 NM_000723
NM_199247
NM_199248
CACNB1


calcium channel, voltage-dependent, beta 1 subunit


chr19_-_14447122 0.945 PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr3_+_49033621 0.945 NM_199073
NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr10_+_99463446 0.943 NM_031484
MARVELD1
MARVEL domain containing 1
chr9_+_138367329 0.942 NM_001145639
GPSM1
G-protein signaling modulator 1
chr9_-_138387926 0.939 NM_052813
NM_052814
CARD9

caspase recruitment domain family, member 9

chr4_+_30330963 0.939 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr17_+_23723113 0.933 NM_015077
SARM1
sterile alpha and TIR motif containing 1
chr2_-_220144511 0.930 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1


chr12_-_92489652 0.928 LOC144481
hypothetical protein LOC144481
chr5_+_149717489 0.927 TCOF1
Treacher Collins-Franceschetti syndrome 1
chr8_+_8597075 0.927 NM_194284
CLDN23
claudin 23
chr16_+_30844707 0.924 FBXL19
F-box and leucine-rich repeat protein 19
chr2_-_73373956 0.920 NM_001965
EGR4
early growth response 4
chr12_+_7038240 0.919 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chr2_+_238673689 0.916 NM_194312
ESPNL
espin-like
chrX_-_152889815 0.913 NM_005334
HCFC1
host cell factor C1 (VP16-accessory protein)
chr16_-_66535923 0.909 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr6_-_110843432 0.909 NM_003649
NM_004032
DDO

D-aspartate oxidase

chr9_-_139128979 0.908 DPP7
dipeptidyl-peptidase 7
chr15_-_87257553 0.907 MFGE8
milk fat globule-EGF factor 8 protein
chr19_-_3928516 0.906 EEF2
eukaryotic translation elongation factor 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.31 4.36e-20 GO:0048856 anatomical structure development
1.33 2.34e-19 GO:0048731 system development
1.28 5.36e-18 GO:0007275 multicellular organismal development
1.26 3.61e-17 GO:0032502 developmental process
1.42 9.55e-15 GO:0009653 anatomical structure morphogenesis
1.34 4.39e-14 GO:0048869 cellular developmental process
1.35 6.35e-14 GO:0030154 cell differentiation
1.40 6.09e-13 GO:0007399 nervous system development
1.18 1.46e-11 GO:0032501 multicellular organismal process
1.49 4.48e-11 GO:0022008 neurogenesis
1.47 1.91e-09 GO:0048699 generation of neurons
1.30 2.11e-09 GO:0048513 organ development
1.42 1.51e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.50 2.63e-08 GO:0030182 neuron differentiation
1.36 2.98e-08 GO:0051239 regulation of multicellular organismal process
1.19 5.21e-08 GO:0023052 signaling
1.12 5.59e-08 GO:0050794 regulation of cellular process
1.49 1.36e-07 GO:0010628 positive regulation of gene expression
1.48 2.72e-07 GO:0045595 regulation of cell differentiation
1.58 2.72e-07 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.60 2.91e-07 GO:0048812 neuron projection morphogenesis
1.56 3.42e-07 GO:0000904 cell morphogenesis involved in differentiation
1.38 3.75e-07 GO:0007154 cell communication
1.11 3.86e-07 GO:0050789 regulation of biological process
1.56 3.92e-07 GO:0048858 cell projection morphogenesis
1.61 4.41e-07 GO:0007409 axonogenesis
1.59 5.36e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.10 6.38e-07 GO:0065007 biological regulation
1.40 6.54e-07 GO:0050793 regulation of developmental process
1.40 7.45e-07 GO:0048468 cell development
1.22 8.00e-07 GO:0048518 positive regulation of biological process
1.68 8.21e-07 GO:0007411 axon guidance
1.54 8.62e-07 GO:0032990 cell part morphogenesis
1.49 9.43e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.48 9.69e-07 GO:0032989 cellular component morphogenesis
1.40 2.08e-06 GO:0009888 tissue development
1.67 2.16e-06 GO:0001501 skeletal system development
1.52 2.30e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.46 2.85e-06 GO:0051254 positive regulation of RNA metabolic process
1.48 3.62e-06 GO:0000902 cell morphogenesis
1.50 4.14e-06 GO:0051253 negative regulation of RNA metabolic process
1.26 4.32e-06 GO:0007166 cell surface receptor linked signaling pathway
1.48 6.03e-06 GO:0048666 neuron development
1.22 8.86e-06 GO:0048522 positive regulation of cellular process
1.47 9.06e-06 GO:0009887 organ morphogenesis
1.41 9.30e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51 1.19e-05 GO:0031175 neuron projection development
1.17 1.35e-05 GO:0007165 signal transduction
1.40 1.51e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.43 3.17e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.39 3.92e-05 GO:0007267 cell-cell signaling
1.83 4.24e-05 GO:0003012 muscle system process
1.40 4.28e-05 GO:2000026 regulation of multicellular organismal development
1.39 5.74e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.41 5.75e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.43 5.81e-05 GO:0030030 cell projection organization
1.34 6.51e-05 GO:0009605 response to external stimulus
1.44 6.66e-05 GO:0010629 negative regulation of gene expression
1.40 8.19e-05 GO:0009890 negative regulation of biosynthetic process
1.36 1.00e-04 GO:0009891 positive regulation of biosynthetic process
1.43 1.14e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.36 1.19e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.42 1.23e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.66 1.35e-04 GO:0045596 negative regulation of cell differentiation
1.94 1.37e-04 GO:0048705 skeletal system morphogenesis
1.63 1.75e-04 GO:0061061 muscle structure development
1.35 1.97e-04 GO:0040011 locomotion
1.25 2.28e-04 GO:0023051 regulation of signaling
1.37 2.90e-04 GO:0007155 cell adhesion
1.37 2.90e-04 GO:0022610 biological adhesion
1.48 2.99e-04 GO:0048646 anatomical structure formation involved in morphogenesis
1.41 3.25e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.46 4.54e-04 GO:0060348 bone development
1.26 5.49e-04 GO:0009966 regulation of signal transduction
1.57 5.77e-04 GO:0060284 regulation of cell development
1.59 6.23e-04 GO:0001944 vasculature development
1.19 6.65e-04 GO:0048519 negative regulation of biological process
1.20 7.41e-04 GO:0048523 negative regulation of cellular process
1.42 8.05e-04 GO:0007186 G-protein coupled receptor protein signaling pathway
2.42 8.27e-04 GO:0045667 regulation of osteoblast differentiation
1.54 8.58e-04 GO:0007389 pattern specification process
1.22 8.61e-04 GO:0048583 regulation of response to stimulus
1.50 9.81e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.55 9.84e-04 GO:0051093 negative regulation of developmental process
1.71 1.24e-03 GO:0007517 muscle organ development
1.45 1.31e-03 GO:0072358 cardiovascular system development
1.45 1.31e-03 GO:0072359 circulatory system development
1.19 1.75e-03 GO:0006355 regulation of transcription, DNA-dependent
1.42 1.83e-03 GO:0006935 chemotaxis
1.42 1.83e-03 GO:0042330 taxis
1.42 2.13e-03 GO:0007417 central nervous system development
1.17 3.15e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51 3.46e-03 GO:0044057 regulation of system process
1.18 3.56e-03 GO:0051252 regulation of RNA metabolic process
1.60 4.99e-03 GO:0003002 regionalization
1.72 5.12e-03 GO:0006936 muscle contraction
1.41 5.20e-03 GO:0019226 transmission of nerve impulse
1.41 5.20e-03 GO:0035637 multicellular organismal signaling
1.29 5.68e-03 GO:0032879 regulation of localization
1.56 5.73e-03 GO:0001568 blood vessel development
1.27 6.12e-03 GO:0010646 regulation of cell communication
1.83 6.95e-03 GO:0010959 regulation of metal ion transport
1.62 7.02e-03 GO:0048514 blood vessel morphogenesis
2.53 7.05e-03 GO:0060349 bone morphogenesis
1.75 8.15e-03 GO:0034330 cell junction organization
1.75 8.15e-03 GO:0043269 regulation of ion transport
1.94 9.01e-03 GO:0030278 regulation of ossification
1.47 1.16e-02 GO:0007420 brain development
1.78 1.23e-02 GO:0001503 ossification
1.78 1.23e-02 GO:0034329 cell junction assembly
1.48 1.48e-02 GO:0045597 positive regulation of cell differentiation
1.42 1.72e-02 GO:0032583 regulation of gene-specific transcription
1.15 1.96e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.74 2.10e-02 GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger
1.24 2.18e-02 GO:0031325 positive regulation of cellular metabolic process
1.37 2.65e-02 GO:0010647 positive regulation of cell communication
1.23 2.69e-02 GO:0009893 positive regulation of metabolic process
2.69 2.92e-02 GO:0007044 cell-substrate junction assembly
3.20 3.23e-02 GO:0045668 negative regulation of osteoblast differentiation
1.84 3.46e-02 GO:0051924 regulation of calcium ion transport
1.50 3.86e-02 GO:0051960 regulation of nervous system development
1.36 3.90e-02 GO:0023056 positive regulation of signaling
1.15 4.20e-02 GO:0009889 regulation of biosynthetic process
1.27 4.48e-02 GO:0031324 negative regulation of cellular metabolic process
1.66 4.57e-02 GO:0009952 anterior/posterior pattern formation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.52 4.26e-05 GO:0031012 extracellular matrix
1.19 2.35e-04 GO:0044459 plasma membrane part
1.13 2.42e-04 GO:0071944 cell periphery
1.13 3.03e-04 GO:0005886 plasma membrane
1.51 6.58e-04 GO:0005578 proteinaceous extracellular matrix
1.41 5.73e-03 GO:0043005 neuron projection
1.32 1.16e-02 GO:0030054 cell junction
1.70 3.35e-02 GO:0044420 extracellular matrix part
2.19 3.81e-02 GO:0044306 neuron projection terminus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.58 1.40e-12 GO:0043565 sequence-specific DNA binding
1.44 6.89e-11 GO:0030528 transcription regulator activity
1.44 1.10e-10 GO:0001071 nucleic acid binding transcription factor activity
1.44 1.10e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.24 1.66e-02 GO:0005102 receptor binding
1.07 2.50e-02 GO:0005515 protein binding
1.88 3.23e-02 GO:0005201 extracellular matrix structural constituent
1.42 4.15e-02 GO:0003779 actin binding
1.32 4.45e-02 GO:0008092 cytoskeletal protein binding