Motif ID: KLF4.p3

Z-value: 2.358


Transcription factors associated with KLF4.p3:

Gene SymbolEntrez IDGene Name
KLF4 9314 Kruppel-like factor 4 (gut)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF4chr9_-_1092901070.448.5e-02Click!


Activity profile for motif KLF4.p3.

activity profile for motif KLF4.p3


Sorted Z-values histogram for motif KLF4.p3

Sorted Z-values for motif KLF4.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF4.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_61742111 2.042 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr19_-_50691999 1.936 NM_005619
NM_206900
RTN2

reticulon 2

chr17_+_45488330 1.824 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr11_-_94603857 1.730 NM_144665
SESN3
sestrin 3
chr11_+_65990869 1.640 NM_001098510
NM_145065
PELI3

pellino homolog 3 (Drosophila)

chr19_+_5855842 1.600 NM_001017921
VMAC
vimentin-type intermediate filament associated coiled-coil protein
chrX_-_149817785 1.565 NM_001184808
NM_031462
NM_134445
NM_134446
CD99L2



CD99 molecule-like 2



chr2_-_37752272 1.515 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr17_+_45488356 1.490 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr19_-_54835162 1.386 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr3_+_137167296 1.385 PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chrX_-_135161185 1.371 NM_001173517
NM_024597
MAP7D3

MAP7 domain containing 3

chr19_+_45976001 1.358 NM_016154
RAB4B-EGLN2
RAB4B
RAB4B-EGLN2 read-through transcript
RAB4B, member RAS oncogene family
chr11_-_65443015 1.347 NM_001135635
NM_031450
C11orf68

chromosome 11 open reading frame 68

chr19_-_45888259 1.312 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr2_-_235070431 1.250 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr11_+_65443303 1.225 NM_006442
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr5_-_2804768 1.203 NM_001134222
NM_033267
IRX2

iroquois homeobox 2

chr14_+_95928189 1.193 NM_152327
AK7
adenylate kinase 7
chr8_-_144887876 1.183 NM_198488
FAM83H
family with sequence similarity 83, member H
chr15_+_61356801 1.170 NM_001145646
NM_031301
APH1B

anterior pharynx defective 1 homolog B (C. elegans)

chr2_-_37752731 1.152 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr15_-_70399301 1.150 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr20_-_56317894 1.137 PPP4R1L
protein phosphatase 4, regulatory subunit 1-like
chr10_+_11824361 1.110 NM_024693
ECHDC3
enoyl CoA hydratase domain containing 3
chr12_+_48303607 1.106 NM_012272
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr19_-_12747263 1.099 HOOK2
hook homolog 2 (Drosophila)
chr13_+_41520888 1.082 NM_152910
NM_178009
DGKH

diacylglycerol kinase, eta

chr13_-_109236897 1.056 NM_003749
IRS2
insulin receptor substrate 2
chrX_+_64804235 1.054 NM_002444
MSN
moesin
chr10_-_134940315 1.052 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr19_-_15204767 1.048 NM_001142886
EPHX3
epoxide hydrolase 3
chr6_-_31805547 1.047 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_+_10574055 1.046 NM_001145056
SLC44A2
solute carrier family 44, member 2
chrX_+_64804259 1.041 MSN
moesin
chr5_-_16989290 1.039 MYO10
myosin X
chr22_-_29015452 1.019 NM_001037666
GATSL3
GATS protein-like 3
chr1_-_113059396 1.011 NM_005167
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chrX_+_64804318 1.005 MSN
moesin
chr6_-_29708647 1.004 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_+_32992131 1.004


chr8_-_22044463 0.991 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr19_-_6718417 0.967 NM_005490
SH2D3A
SH2 domain containing 3A
chr22_-_29052863 0.953 NM_031937
TBC1D10A
TBC1 domain family, member 10A
chr12_+_56406296 0.943 LOC100130776
hypothetical LOC100130776
chr19_+_60487345 0.933 NM_032430
BRSK1
BR serine/threonine kinase 1
chr12_-_53099203 0.933 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_-_45759691 0.932 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chr10_-_105604942 0.931 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr22_-_49050847 0.927 NM_002751
MAPK11
mitogen-activated protein kinase 11
chr12_-_53099277 0.923 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_6243621 0.923 NM_207370
GPR153
G protein-coupled receptor 153
chr19_-_19599973 0.912 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr3_+_185762233 0.911 NM_004443
EPHB3
EPH receptor B3
chr11_-_62146144 0.910 B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr19_+_18608827 0.909 NM_018316
KLHL26
kelch-like 26 (Drosophila)
chr11_-_11987115 0.908 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr14_-_104515738 0.900 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chrX_-_149817720 0.898 CD99L2
CD99 molecule-like 2
chr19_-_48976852 0.897 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr8_-_144722141 0.886 C8orf73
chromosome 8 open reading frame 73
chrX_+_152891184 0.885 NM_003492
TMEM187
transmembrane protein 187
chr9_-_100057313 0.884 TBC1D2
TBC1 domain family, member 2
chr12_-_53099269 0.883 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_-_51900388 0.876 NM_001042728
RARG
retinoic acid receptor, gamma
chr11_-_127897271 0.871 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr5_+_176006993 0.867 NM_001006616
NM_012171
NM_130465
TSPAN17


tetraspanin 17


chr1_+_156229686 0.864 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr9_+_129962292 0.863 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr7_+_100584397 0.857 NM_001283
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr1_-_46855116 0.857 NM_201403
MOBKL2C
MOB1, Mps One Binder kinase activator-like 2C (yeast)
chr8_+_32525269 0.856 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr9_+_139006663 0.854 NM_183241
C9orf142
chromosome 9 open reading frame 142
chrX_-_134060329 0.846 NCRNA00087
non-protein coding RNA 87
chr5_+_176007095 0.840 TSPAN17
tetraspanin 17
chr2_+_84986273 0.838 NM_021103
TMSB10
thymosin beta 10
chr5_+_176492662 0.837 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr9_-_109291575 0.835 KLF4
Kruppel-like factor 4 (gut)
chr1_+_231530136 0.823 NM_032435
KIAA1804
mixed lineage kinase 4
chrX_-_152642716 0.820 NM_001139457
NM_001139441
BCAP31

B-cell receptor-associated protein 31

chr22_+_41877502 0.815 TSPO
translocator protein (18kDa)
chr11_+_63829616 0.814 NM_004451
ESRRA
estrogen-related receptor alpha
chr11_+_65443452 0.804 DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_-_48977247 0.804 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chrX_+_153318452 0.799 NM_001493
GDI1
GDP dissociation inhibitor 1
chr9_-_129371171 0.793 NM_022833
FAM129B
family with sequence similarity 129, member B
chr5_+_176786279 0.790 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr19_+_50535837 0.789 NM_177417
KLC3
kinesin light chain 3
chr19_+_60283571 0.788 NM_017729
EPS8L1
EPS8-like 1
chr2_+_241023908 0.786 GPC1
glypican 1
chr14_-_104705753 0.781 JAG2
jagged 2
chr19_+_40298571 0.776 NM_001136007
NM_001136008
NM_001136009
NM_001136010
NM_001136011
NM_001136012
NM_005971
NM_021910
FXYD3







FXYD domain containing ion transport regulator 3







chr17_-_78249750 0.775 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr3_-_52418933 0.774 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr7_+_73136085 0.771 NM_002314
LIMK1
LIM domain kinase 1
chr19_+_50196526 0.769 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr11_+_65443484 0.766 DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_-_2672337 0.766 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr19_-_18493886 0.765 NM_006532
ELL
elongation factor RNA polymerase II
chr19_+_45811316 0.762 LTBP4
latent transforming growth factor beta binding protein 4
chr11_-_525532 0.760 NM_001130442
NM_005343
NM_176795
HRAS


v-Ha-ras Harvey rat sarcoma viral oncogene homolog


chr19_-_18493847 0.751 ELL
elongation factor RNA polymerase II
chr18_-_50004770 0.747 MBD2
methyl-CpG binding domain protein 2
chrX_-_152643001 0.744


chr1_+_110554836 0.732 NM_001039574
NM_004978
KCNC4

potassium voltage-gated channel, Shaw-related subfamily, member 4

chr9_-_138560058 0.730 NM_017617
NOTCH1
notch 1
chr6_-_42527760 0.727 NM_033502
TRERF1
transcriptional regulating factor 1
chr14_+_104244998 0.727 INF2
inverted formin, FH2 and WH2 domain containing
chr19_-_45663463 0.723 NM_000713
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chrX_-_152517629 0.723 FAM58A
family with sequence similarity 58, member A
chr7_+_100302885 0.722 NM_003302
TRIP6
thyroid hormone receptor interactor 6
chr9_-_129370954 0.718 FAM129B
family with sequence similarity 129, member B
chr12_-_46585032 0.716 NM_000376
NM_001017535
VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

chrX_-_152643042 0.710 BCAP31
B-cell receptor-associated protein 31
chr3_+_128874458 0.696 NM_172027
ABTB1
ankyrin repeat and BTB (POZ) domain containing 1
chr3_-_46710137 0.694 NM_001190707
NM_147129
ALS2CL

ALS2 C-terminal like

chr1_+_182622987 0.692 C1orf21
chromosome 1 open reading frame 21
chr17_+_39990124 0.691 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr1_-_32940850 0.688 SYNC
syncoilin, intermediate filament protein
chr10_-_3204955 0.685 PITRM1
pitrilysin metallopeptidase 1
chr1_-_29321599 0.684 NM_001171868
TMEM200B
transmembrane protein 200B
chr11_-_56848859 0.683 NM_033396
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr11_-_11987458 0.679 NM_013253
DKK3
dickkopf homolog 3 (Xenopus laevis)
chrX_-_152643016 0.676 NM_005745
BCAP31
B-cell receptor-associated protein 31
chr11_+_76249550 0.675 NM_018367
ACER3
alkaline ceramidase 3
chr7_+_115926855 0.674 CAV2
caveolin 2
chr11_-_11987414 0.673 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr18_-_50004932 0.673 MBD2
methyl-CpG binding domain protein 2
chr8_+_144888275 0.669 LOC100128338
hypothetical LOC100128338
chr4_+_87734489 0.668 NM_006264
NM_080683
NM_080684
NM_080685
PTPN13



protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)



chr9_+_139619918 0.668 ARRDC1
arrestin domain containing 1
chr18_+_32131628 0.667 NM_025135
FHOD3
formin homology 2 domain containing 3
chr1_+_149750485 0.667 NM_020770
CGN
cingulin
chrX_-_152517815 0.667 NM_001130997
NM_152274
FAM58A

family with sequence similarity 58, member A

chr1_-_27211913 0.665 NM_052943
FAM46B
family with sequence similarity 46, member B
chr5_+_10617431 0.664 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr12_-_47868563 0.662 TUBA1A
tubulin, alpha 1a
chr17_-_7323528 0.658 ZBTB4
zinc finger and BTB domain containing 4
chr22_-_17489718 0.657 DGCR2
DiGeorge syndrome critical region gene 2
chr12_+_115455579 0.654 NCRNA00173
non-protein coding RNA 173
chr21_+_34367747 0.653 MRPS6
mitochondrial ribosomal protein S6
chr7_-_72791090 0.651 NM_001145364
NM_148912
NM_148913
ABHD11


abhydrolase domain containing 11


chr11_-_11987198 0.651 NM_015881
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr9_+_35819375 0.651 NM_001042590
TMEM8B
transmembrane protein 8B
chr19_+_7801110 0.651 NM_145245
EVI5L
ecotropic viral integration site 5-like
chr3_-_52419056 0.651 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr15_+_39907447 0.649 NM_001114632
NM_001198588
NM_005090
JMJD7
JMJD7-PLA2G4B

jumonji domain containing 7
JMJD7-PLA2G4B readthrough

chr11_-_66877519 0.647 NM_021173
POLD4
polymerase (DNA-directed), delta 4
chr10_+_112247614 0.637 NM_004419
DUSP5
dual specificity phosphatase 5
chr2_+_241023703 0.633 NM_002081
GPC1
glypican 1
chr11_+_56984702 0.632 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr9_-_35101534 0.630 KIAA1539
KIAA1539
chr4_+_79691875 0.627 ANXA3
annexin A3
chr22_+_36632242 0.626 NM_033386
MICALL1
MICAL-like 1
chr18_+_11971457 0.622 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr8_-_145088679 0.621 NM_201383
PLEC
plectin
chr9_-_130830255 0.620 NM_020145
SH3GLB2
SH3-domain GRB2-like endophilin B2
chr17_-_73867748 0.619 NM_003955
SOCS3
suppressor of cytokine signaling 3
chrX_+_117513899 0.617 NM_144658
DOCK11
dedicator of cytokinesis 11
chr3_-_52065130 0.617 NM_001947
DUSP7
dual specificity phosphatase 7
chr9_+_139619969 0.614 ARRDC1
arrestin domain containing 1
chr11_+_64838882 0.612 NM_006779
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr22_-_37878394 0.611 NM_175709
CBX7
chromobox homolog 7
chr1_-_208046011 0.608 NM_006147
IRF6
interferon regulatory factor 6
chr8_+_144870482 0.606 NM_139021
MAPK15
mitogen-activated protein kinase 15
chr12_+_12935619 0.603 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr9_+_138497767 0.602 NM_152571
C9orf163
chromosome 9 open reading frame 163
chrX_+_17303458 0.599 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_-_11788550 0.599 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr3_-_48607596 0.598 NM_000094
COL7A1
collagen, type VII, alpha 1
chr17_-_40674883 0.597


chr8_-_145122884 0.596 NM_000445
PLEC
plectin
chr21_+_46568460 0.595 NM_006031
PCNT
pericentrin
chr8_-_127639647 0.591 FAM84B
family with sequence similarity 84, member B
chr12_-_48508411 0.590 NM_001037806
NCKAP5L
NCK-associated protein 5-like
chr19_+_53819460 0.589 SPHK2
sphingosine kinase 2
chr1_-_33420213 0.585 NM_018207
TRIM62
tripartite motif containing 62
chrX_+_48915127 0.584 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr7_-_87687302 0.581 NM_003130
SRI
sorcin
chr11_-_62145952 0.579 NM_012200
B3GAT3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr19_+_54558798 0.578 NM_001197302
NM_001197301
NM_014419
DKKL1


dickkopf-like 1


chr2_-_1727292 0.577 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr10_-_116154504 0.576 NM_001001936
NM_032550
AFAP1L2

actin filament associated protein 1-like 2

chr12_+_56202874 0.576 NM_052897
MBD6
methyl-CpG binding domain protein 6
chr13_+_72531098 0.575 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr19_-_10807866 0.575 NM_006858
TMED1
transmembrane emp24 protein transport domain containing 1
chr8_+_22513043 0.574 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr6_-_31805932 0.574 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr9_+_35819208 0.573 NM_016446
NM_001042589
TMEM8B

transmembrane protein 8B

chr18_+_54682261 0.570 ZNF532
zinc finger protein 532
chr19_+_60487578 0.570 BRSK1
BR serine/threonine kinase 1
chr5_-_176857158 0.569 PDLIM7
PDZ and LIM domain 7 (enigma)
chr9_-_35101592 0.568 KIAA1539
KIAA1539
chr11_-_125730655 0.566 FLJ39051
hypothetical LOC399972
chr1_+_35031185 0.566 NM_002060
GJA4
gap junction protein, alpha 4, 37kDa
chr22_-_17546296 0.566 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr4_+_154606900 0.565 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr2_-_120697148 0.565 TMEM185B
transmembrane protein 185B (pseudogene)
chr3_+_38182251 0.565 OXSR1
oxidative-stress responsive 1
chr22_+_41877470 0.564 NM_000714
NM_007311
TSPO

translocator protein (18kDa)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.07 3.29e-17 GO:0009987 cellular process
1.10 1.01e-10 GO:0044237 cellular metabolic process
1.09 6.92e-09 GO:0044238 primary metabolic process
1.13 1.04e-08 GO:0016043 cellular component organization
1.15 1.37e-08 GO:0071842 cellular component organization at cellular level
1.11 9.82e-08 GO:0044260 cellular macromolecule metabolic process
1.19 1.12e-07 GO:0006996 organelle organization
1.12 1.31e-07 GO:0071840 cellular component organization or biogenesis
1.14 1.45e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.08 1.48e-07 GO:0008152 metabolic process
1.18 3.91e-07 GO:0006464 protein modification process
1.07 2.36e-06 GO:0050794 regulation of cellular process
1.07 3.01e-06 GO:0050789 regulation of biological process
1.19 9.97e-06 GO:0033036 macromolecule localization
1.06 1.06e-05 GO:0065007 biological regulation
1.09 1.42e-05 GO:0043170 macromolecule metabolic process
1.13 2.57e-05 GO:0044267 cellular protein metabolic process
1.15 3.47e-05 GO:0043412 macromolecule modification
1.12 5.72e-05 GO:0051234 establishment of localization
1.11 1.70e-04 GO:0006810 transport
1.20 2.02e-04 GO:0008104 protein localization
1.10 8.71e-04 GO:0051179 localization
1.11 1.17e-03 GO:0019538 protein metabolic process
1.20 1.81e-03 GO:0008219 cell death
1.25 2.83e-03 GO:0000278 mitotic cell cycle
1.22 3.38e-03 GO:0006915 apoptosis
1.20 3.66e-03 GO:0016265 death
1.22 4.56e-03 GO:0012501 programmed cell death
1.12 9.41e-03 GO:0048523 negative regulation of cellular process
1.49 9.54e-03 GO:0051789 response to protein stimulus
1.15 1.04e-02 GO:0035556 intracellular signal transduction
1.19 1.08e-02 GO:0045184 establishment of protein localization
1.11 1.44e-02 GO:0048519 negative regulation of biological process
1.17 1.68e-02 GO:0007049 cell cycle
1.21 1.70e-02 GO:0022403 cell cycle phase
1.09 1.81e-02 GO:0006807 nitrogen compound metabolic process
1.22 2.07e-02 GO:0005975 carbohydrate metabolic process
1.09 2.31e-02 GO:0007165 signal transduction
1.14 2.69e-02 GO:0009966 regulation of signal transduction
1.31 2.97e-02 GO:0051329 interphase of mitotic cell cycle
1.08 2.98e-02 GO:0023052 signaling
1.19 3.25e-02 GO:0022402 cell cycle process
1.13 3.29e-02 GO:0023051 regulation of signaling
1.18 3.53e-02 GO:0015031 protein transport
1.09 3.78e-02 GO:0034641 cellular nitrogen compound metabolic process
1.30 3.84e-02 GO:0051325 interphase
1.30 3.90e-02 GO:0048285 organelle fission

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 1.74e-33 GO:0005622 intracellular
1.08 1.43e-31 GO:0044424 intracellular part
1.11 1.35e-27 GO:0005737 cytoplasm
1.09 7.56e-26 GO:0043229 intracellular organelle
1.09 1.01e-25 GO:0043226 organelle
1.09 7.63e-21 GO:0043231 intracellular membrane-bounded organelle
1.09 1.00e-20 GO:0043227 membrane-bounded organelle
1.13 1.23e-20 GO:0044444 cytoplasmic part
1.12 5.66e-15 GO:0044446 intracellular organelle part
1.11 1.10e-14 GO:0044422 organelle part
1.10 8.28e-12 GO:0005634 nucleus
1.19 2.63e-11 GO:0005829 cytosol
1.18 2.05e-07 GO:0005856 cytoskeleton
1.12 8.77e-07 GO:0043234 protein complex
1.21 1.71e-06 GO:0044430 cytoskeletal part
1.26 6.65e-06 GO:0015630 microtubule cytoskeleton
1.16 8.21e-06 GO:0012505 endomembrane system
1.12 1.29e-05 GO:0043228 non-membrane-bounded organelle
1.12 1.29e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.02 3.24e-05 GO:0044464 cell part
1.02 3.60e-05 GO:0005623 cell
1.13 4.18e-05 GO:0070013 intracellular organelle lumen
1.17 4.71e-05 GO:0005654 nucleoplasm
1.13 4.71e-05 GO:0044428 nuclear part
1.19 1.19e-04 GO:0005794 Golgi apparatus
1.14 1.44e-04 GO:0031981 nuclear lumen
1.12 1.90e-04 GO:0043233 organelle lumen
1.12 2.32e-04 GO:0031974 membrane-enclosed lumen
1.09 3.46e-04 GO:0032991 macromolecular complex
1.23 5.83e-04 GO:0030054 cell junction
1.55 1.47e-03 GO:0005925 focal adhesion
1.25 2.42e-03 GO:0000139 Golgi membrane
1.44 2.65e-03 GO:0005912 adherens junction
1.11 2.83e-03 GO:0031090 organelle membrane
1.31 3.36e-03 GO:0015629 actin cytoskeleton
1.51 3.41e-03 GO:0030055 cell-substrate junction
1.39 6.89e-03 GO:0070161 anchoring junction
1.50 7.38e-03 GO:0005924 cell-substrate adherens junction
1.38 7.70e-03 GO:0031252 cell leading edge
1.36 1.51e-02 GO:0005819 spindle
1.23 1.56e-02 GO:0044427 chromosomal part
1.26 2.12e-02 GO:0005815 microtubule organizing center
1.20 2.35e-02 GO:0044431 Golgi apparatus part
1.50 2.86e-02 GO:0016585 chromatin remodeling complex
1.27 4.66e-02 GO:0005874 microtubule
1.56 4.80e-02 GO:0000922 spindle pole

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 5.72e-33 GO:0005515 protein binding
1.06 2.02e-21 GO:0005488 binding
1.14 3.07e-06 GO:0000166 nucleotide binding
1.14 4.61e-05 GO:0017076 purine nucleotide binding
1.14 4.82e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.14 5.20e-05 GO:0032553 ribonucleotide binding
1.14 5.20e-05 GO:0032555 purine ribonucleotide binding
1.32 1.43e-04 GO:0000988 protein binding transcription factor activity
1.32 1.43e-04 GO:0000989 transcription factor binding transcription factor activity
1.31 1.90e-04 GO:0003712 transcription cofactor activity
1.20 2.16e-03 GO:0019899 enzyme binding
1.26 2.53e-03 GO:0019904 protein domain specific binding
1.23 6.82e-03 GO:0008092 cytoskeletal protein binding
1.06 1.14e-02 GO:0003824 catalytic activity
1.34 1.31e-02 GO:0003713 transcription coactivator activity
1.26 1.75e-02 GO:0005525 GTP binding
2.32 2.91e-02 GO:0070412 R-SMAD binding