Motif ID: MYOD1.p2

Z-value: 2.521


Transcription factors associated with MYOD1.p2:

Gene SymbolEntrez IDGene Name
MYOD1 4654 myogenic differentiation 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYOD1chr11_+_176976850.543.2e-02Click!


Activity profile for motif MYOD1.p2.

activity profile for motif MYOD1.p2


Sorted Z-values histogram for motif MYOD1.p2

Sorted Z-values for motif MYOD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYOD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_23754772 2.834 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr16_+_66236559 2.331 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr2_+_219453487 2.282 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr7_+_50314801 2.277 NM_006060
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr3_-_13436802 2.274 NM_024923
NUP210
nucleoporin 210kDa
chr4_+_76077229 2.204 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr16_-_87570716 2.143 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr16_+_23754822 2.132 PRKCB
protein kinase C, beta
chr17_+_73676219 2.060 NM_004710
SYNGR2
synaptogyrin 2
chr17_-_36577949 1.916 NM_033187
KRTAP4-3
keratin associated protein 4-3
chr2_+_176761552 1.776 NM_024501
HOXD1
homeobox D1
chr11_+_63864263 1.755 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr8_-_143692814 1.752 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr17_+_36493927 1.591 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr17_-_36570508 1.578 NM_032524
KRTAP4-4
keratin associated protein 4-4
chr16_+_66236512 1.571 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr16_+_23754860 1.554 PRKCB
protein kinase C, beta
chr2_+_79593567 1.540 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr16_-_87535106 1.536 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr2_-_6923215 1.523 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr17_+_43165608 1.504 NM_013351
TBX21
T-box 21
chr11_-_86060812 1.488 NM_001014811
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr5_+_139008091 1.477 CXXC5
CXXC finger protein 5
chr2_+_227737524 1.459 NM_000091
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr1_+_89763030 1.452 LRRC8B
leucine rich repeat containing 8 family, member B
chr19_-_7845325 1.448 NM_001190467
FLJ22184
hypothetical protein FLJ22184
chr16_+_29582069 1.444 NM_003123
SPN
sialophorin
chr1_-_40027097 1.378 BMP8B
bone morphogenetic protein 8b
chrX_+_117992603 1.369 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr15_+_86983038 1.342 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr5_-_150583842 1.319 NM_015621
CCDC69
coiled-coil domain containing 69
chr16_+_29582065 1.317 SPN
sialophorin
chr3_+_141879555 1.315 NM_152616
TRIM42
tripartite motif containing 42
chr1_+_89762984 1.311 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr5_-_150583808 1.306 CCDC69
coiled-coil domain containing 69
chr11_+_817584 1.296 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr9_+_137733851 1.293 NM_020822
KCNT1
potassium channel, subfamily T, member 1
chr9_+_37640996 1.260 NM_014907
FRMPD1
FERM and PDZ domain containing 1
chr5_-_139402989 1.253 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
NRG2




neuregulin 2




chr7_+_149651202 1.239 NM_001142928
NM_023942
LRRC61

leucine rich repeat containing 61

chr16_+_29581783 1.231 NM_001030288
SPN
sialophorin
chr4_+_42094612 1.228 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr17_+_23824784 1.226 NM_001145975
NM_001145976
NM_003984
SLC13A2


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2


chr10_-_98470164 1.221 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr16_+_23754997 1.212 PRKCB
protein kinase C, beta
chr8_-_81246215 1.211 NM_001025253
NM_005079
TPD52

tumor protein D52

chr20_+_60744268 1.193 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr20_+_60744231 1.192 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr9_+_70509925 1.191 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr6_+_137285071 1.172 NM_001008783
SLC35D3
solute carrier family 35, member D3
chr13_+_77170470 1.170 NM_001040153
SLAIN1
SLAIN motif family, member 1
chr6_+_135544170 1.151 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr11_+_117362333 1.127 IL10RA
interleukin 10 receptor, alpha
chr9_-_139235595 1.126 NM_031297
RNF208
ring finger protein 208
chr22_-_17303654 1.122 PRODH
proline dehydrogenase (oxidase) 1
chr11_-_86061003 1.112 NM_006680
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr8_+_72918772 1.103 LOC100132891
hypothetical LOC100132891
chr1_-_166171838 1.082 NM_015415
BRP44
brain protein 44
chr15_-_73036827 1.081 NM_017793
RPP25
ribonuclease P/MRP 25kDa subunit
chr1_-_218168137 1.080 SLC30A10
solute carrier family 30, member 10
chr5_+_168996816 1.077 NM_004946
DOCK2
dedicator of cytokinesis 2
chr6_+_12825818 1.067 NM_030948
PHACTR1
phosphatase and actin regulator 1
chr11_+_59979857 1.066 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr3_-_123223658 1.064 NM_175924
ILDR1
immunoglobulin-like domain containing receptor 1
chr1_+_32512298 1.058 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr6_+_135544138 1.055 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr11_-_66945190 1.053 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chrX_-_19918958 1.053 LOC729609
hypothetical LOC729609
chr5_+_168996852 1.052 DOCK2
dedicator of cytokinesis 2
chr12_+_47810915 1.051


chr11_+_6237541 1.050 NM_176875
CCKBR
cholecystokinin B receptor
chr22_-_35938298 1.037 NM_001051
SSTR3
somatostatin receptor 3
chr2_+_79593679 1.026 CTNNA2
catenin (cadherin-associated protein), alpha 2
chr12_+_47658502 1.020 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr3_+_114733907 1.017 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr17_-_31441390 1.005 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr6_+_111515473 0.997 NM_018593
SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr6_+_135544214 0.993 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr5_-_132976121 0.992 NM_015082
FSTL4
follistatin-like 4
chr3_-_184363126 0.990 LAMP3
lysosomal-associated membrane protein 3
chr7_+_149201962 0.986 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr16_+_19087035 0.979 NM_016524
SYT17
synaptotagmin XVII
chr7_+_149651481 0.979 LRRC61
leucine rich repeat containing 61
chr15_-_43457916 0.964 GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr9_-_91302707 0.959 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr1_+_12149662 0.948 TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr5_-_66528330 0.944 NM_005582
CD180
CD180 molecule
chrX_+_129133234 0.941 NM_004794
RAB33A
RAB33A, member RAS oncogene family
chr18_-_5882102 0.941 NM_001080209
TMEM200C
transmembrane protein 200C
chr14_+_91858677 0.941 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr16_+_76690664 0.940 NM_016373
NM_130791
NM_130844
WWOX


WW domain containing oxidoreductase


chr20_+_36867708 0.936 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory (inhibitor) subunit 16B

chr20_-_3635774 0.926 NM_023068
SIGLEC1
sialic acid binding Ig-like lectin 1, sialoadhesin
chr19_-_55560686 0.923 NM_004851
NAPSA
napsin A aspartic peptidase
chr8_-_41641881 0.922 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr15_-_72288362 0.919 NM_001142617
NM_001142619
NM_001142620
STRA6


stimulated by retinoic acid gene 6 homolog (mouse)


chr3_+_39826032 0.918 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr19_+_1033816 0.914 HMHA1
histocompatibility (minor) HA-1
chr9_+_94987032 0.913 NM_006648
WNK2
WNK lysine deficient protein kinase 2
chr12_-_56159631 0.912 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr1_-_27834210 0.910 NM_005248
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr16_-_49272741 0.910 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr9_+_91409746 0.910 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr11_+_22171150 0.898 NM_001142649
NM_213599
ANO5

anoctamin 5

chr2_-_227737009 0.894 COL4A4
collagen, type IV, alpha 4
chr16_+_25610847 0.884 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr1_+_12149637 0.884 NM_001066
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr22_+_38213174 0.881 NM_001098270
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr20_-_4752067 0.881 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr5_-_88235624 0.880 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr16_-_49272617 0.879 SNX20
sorting nexin 20
chr3_-_71916877 0.876 NM_001126128
NM_021935
PROK2

prokineticin 2

chr11_-_86061301 0.874 NM_001161586
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr17_+_4560680 0.868 ARRB2
arrestin, beta 2
chr11_-_57173823 0.860 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr4_-_38534802 0.859 NM_006068
TLR6
toll-like receptor 6
chr9_-_131422842 0.859 NM_199350
C9orf50
chromosome 9 open reading frame 50
chr11_-_124137260 0.858 NM_138961
ESAM
endothelial cell adhesion molecule
chr19_+_17277476 0.849 NM_023937
MRPL34
mitochondrial ribosomal protein L34
chr1_-_200397300 0.845 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr16_-_29929801 0.843 NM_003586
DOC2A
double C2-like domains, alpha
chr19_+_14405216 0.843 PKN1
protein kinase N1
chr3_+_85090721 0.840 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr17_-_35975227 0.838 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr6_+_11646472 0.833 NM_001100829
TMEM170B
transmembrane protein 170B
chr8_+_61753912 0.831 CHD7
chromodomain helicase DNA binding protein 7
chr15_-_90999606 0.831 NM_207446
FAM174B
family with sequence similarity 174, member B
chr6_+_111515341 0.830 SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr12_-_47774837 0.830 NM_021044
DHH
desert hedgehog
chr18_+_58143499 0.829 NM_003839
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr4_+_107036076 0.825 NPNT
nephronectin
chr4_-_40326603 0.824 NM_001098634
RBM47
RNA binding motif protein 47
chr1_-_23729871 0.823 E2F2
E2F transcription factor 2
chr7_+_119700924 0.818 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr9_-_6635564 0.816 NM_000170
GLDC
glycine dehydrogenase (decarboxylating)
chr1_-_246804680 0.810 NM_001001821
OR2T34
olfactory receptor, family 2, subfamily T, member 34
chr1_-_9052207 0.810 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr10_+_92970302 0.807 NM_032373
PCGF5
polycomb group ring finger 5
chr4_+_107036042 0.806 NM_001033047
NM_001184690
NM_001184691
NM_001184692
NM_001184693
NPNT




nephronectin




chr5_+_139008667 0.803 CXXC5
CXXC finger protein 5
chr10_-_120345148 0.791 NM_004248
PRLHR
prolactin releasing hormone receptor
chr6_-_163068788 0.786 PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
chr5_+_142130475 0.780 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr19_+_59077241 0.779 NM_002739
PRKCG
protein kinase C, gamma
chr20_-_49592654 0.778 NM_012340
NM_173091
NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

chr9_-_129573330 0.777 NM_005489
SH2D3C
SH2 domain containing 3C
chr1_+_32489426 0.775 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr17_-_40839082 0.774 NM_001159330
ARHGAP27
Rho GTPase activating protein 27
chr12_-_107238568 0.771 NM_001142345
CMKLR1
chemokine-like receptor 1
chr1_-_159306273 0.769 ARHGAP30
Rho GTPase activating protein 30
chr6_-_41276901 0.767 NM_024807
TREML2
triggering receptor expressed on myeloid cells-like 2
chr7_+_87401368 0.762 NM_004194
NM_016351
NM_021721
NM_021722
NM_021723
ADAM22




ADAM metallopeptidase domain 22




chr16_-_1944671 0.762 NM_005061
RPL3L
ribosomal protein L3-like
chr6_-_88911708 0.760 NM_033181
CNR1
cannabinoid receptor 1 (brain)
chr4_+_39874921 0.760 NM_004310
RHOH
ras homolog gene family, member H
chr4_+_7245218 0.760 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr4_-_46086218 0.759 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr16_+_29582480 0.754 SPN
sialophorin
chr1_-_9052253 0.754 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr16_+_55456619 0.752 NM_000339
NM_001126107
NM_001126108
SLC12A3


solute carrier family 12 (sodium/chloride transporters), member 3


chr10_+_49563520 0.746 NM_020945
WDFY4
WDFY family member 4
chr5_+_169749068 0.745


chr12_+_48784057 0.742 NM_005276
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr1_-_39877883 0.741 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr1_-_153107084 0.741


chr19_-_56018815 0.738 NM_002257
KLK1
kallikrein 1
chr1_-_40555511 0.737 NM_001852
COL9A2
collagen, type IX, alpha 2
chr1_-_92722088 0.731 GFI1
growth factor independent 1 transcription repressor
chr4_-_47966570 0.730 NM_003215
TEC
tec protein tyrosine kinase
chr2_+_208979800 0.730 NM_005048
PTH2R
parathyroid hormone 2 receptor
chr9_-_122731263 0.729 NM_001190945
TRAF1
TNF receptor-associated factor 1
chr20_-_62186155 0.728 NM_001007125
C20orf201
chromosome 20 open reading frame 201
chr15_-_43458247 0.726 NM_001482
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr6_-_37333872 0.725 NM_001162900
TMEM217
transmembrane protein 217
chr6_-_32742265 0.725 NM_002123
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr11_-_35397675 0.723 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr20_-_49592444 0.721 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr1_-_40140126 0.717 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr3_+_45902999 0.715 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr12_+_54361596 0.711 NM_152637
METTL7B
methyltransferase like 7B
chr1_+_66030780 0.707 NM_001037341
PDE4B
phosphodiesterase 4B, cAMP-specific
chr19_+_8384181 0.707 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr1_-_159306037 0.706 ARHGAP30
Rho GTPase activating protein 30
chr4_+_82171142 0.703 NM_001201
BMP3
bone morphogenetic protein 3
chr11_-_47356562 0.701 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr2_+_198377561 0.700 NM_006226
PLCL1
phospholipase C-like 1
chr16_+_88207457 0.699 DPEP1
dipeptidase 1 (renal)
chr19_-_6432765 0.696 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr22_+_22566595 0.696 MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr17_+_40655060 0.696 NM_005892
FMNL1
formin-like 1
chr1_-_92724181 0.695 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr22_-_49317408 0.695 ODF3B
outer dense fiber of sperm tails 3B
chr9_-_85622366 0.695 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr5_+_176726918 0.694 RGS14
regulator of G-protein signaling 14
chr1_-_39877928 0.692 NM_014571
HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr19_+_1033797 0.692 HMHA1
histocompatibility (minor) HA-1
chr6_-_25019173 0.690 NM_014722
FAM65B
family with sequence similarity 65, member B
chrX_+_117992623 0.686 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr8_-_57286381 0.685 PLAG1
pleiomorphic adenoma gene 1
chr14_-_105900687 0.683 IGHA1
IGHD
IGHG3
IGHM
SKAP2
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
src kinase associated phosphoprotein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.49 1.26e-05 GO:0006811 ion transport
1.56 2.26e-03 GO:0030001 metal ion transport
1.68 2.64e-03 GO:0044057 regulation of system process
1.48 9.45e-03 GO:0006812 cation transport
1.39 1.50e-02 GO:0055085 transmembrane transport
1.19 2.13e-02 GO:0006810 transport
1.90 2.63e-02 GO:0006813 potassium ion transport
1.39 4.12e-02 GO:0007267 cell-cell signaling
2.02 4.40e-02 GO:0002791 regulation of peptide secretion
2.02 4.40e-02 GO:0090087 regulation of peptide transport
1.18 4.51e-02 GO:0051234 establishment of localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 8.49e-04 GO:0005886 plasma membrane
1.15 1.18e-03 GO:0071944 cell periphery
1.22 3.64e-03 GO:0044459 plasma membrane part
1.49 1.96e-02 GO:0045202 synapse
2.12 2.01e-02 GO:0008021 synaptic vesicle
1.08 2.42e-02 GO:0016020 membrane
2.12 3.61e-02 GO:0045095 keratin filament

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.52 2.70e-07 GO:0022891 substrate-specific transmembrane transporter activity
1.56 3.55e-07 GO:0015075 ion transmembrane transporter activity
1.48 1.14e-06 GO:0022857 transmembrane transporter activity
1.40 4.86e-06 GO:0005215 transporter activity
1.72 6.01e-06 GO:0022838 substrate-specific channel activity
1.68 1.75e-05 GO:0015267 channel activity
1.42 1.83e-05 GO:0022892 substrate-specific transporter activity
1.68 2.02e-05 GO:0022803 passive transmembrane transporter activity
1.58 2.30e-05 GO:0008324 cation transmembrane transporter activity
1.68 4.13e-05 GO:0005216 ion channel activity
1.81 9.40e-05 GO:0005261 cation channel activity
3.84 1.82e-02 GO:0005227 calcium activated cation channel activity
1.94 1.99e-02 GO:0005267 potassium channel activity
1.84 3.58e-02 GO:0008509 anion transmembrane transporter activity
1.56 3.81e-02 GO:0022836 gated channel activity