Motif ID: NFIL3.p2

Z-value: 1.146


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFIL3chr9_-_93225780,
chr9_-_93225961
0.175.3e-01Click!


Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_65503011 1.306 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr6_+_167445284 1.107 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr11_-_10487212 1.057 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chrX_+_117992603 1.027 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr7_-_142369519 0.941 KEL
Kell blood group, metallo-endopeptidase
chr7_-_142369534 0.811 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr10_-_82039158 0.794 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr2_+_201464884 0.757 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr10_-_52315436 0.743 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr14_+_23633101 0.722 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr6_-_123999640 0.679 NM_006073
TRDN
triadin
chr5_-_14924555 0.657 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr2_-_99472843 0.654 REV1
REV1 homolog (S. cerevisiae)
chr9_+_27514311 0.634 NM_020124
IFNK
interferon, kappa
chr4_+_110574376 0.601 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chr9_-_122679387 0.597 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr6_-_27988152 0.582 NM_033057
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr1_+_11171967 0.573 NM_021146
ANGPTL7
angiopoietin-like 7
chr9_-_122679283 0.571 PHF19
PHD finger protein 19
chr4_+_170817787 0.557 CLCN3
chloride channel 3
chrX_+_100111352 0.555 NM_001012990
NM_001162490
NM_001162491
ARL13A


ADP-ribosylation factor-like 13A


chr6_-_136889302 0.552 MAP7
microtubule-associated protein 7
chr12_+_54316910 0.547 NM_206899
OR10P1
olfactory receptor, family 10, subfamily P, member 1
chr1_+_25629968 0.538 NM_018202
TMEM57
transmembrane protein 57
chr3_+_2528272 0.536 CNTN4
contactin 4
chr9_+_126460511 0.536


chr8_-_102287083 0.528 NM_001042510
NM_016096
ZNF706

zinc finger protein 706

chr16_-_69876262 0.526 FTSJD1
FtsJ methyltransferase domain containing 1
chr2_-_63518589 0.517 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chr17_+_59205289 0.516 NM_007372
NM_203499
DDX42

DEAD (Asp-Glu-Ala-Asp) box polypeptide 42

chr10_+_135190855 0.511 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr4_+_110574420 0.508 SEC24B
SEC24 family, member B (S. cerevisiae)
chr15_-_63871492 0.502 DENND4A
DENN/MADD domain containing 4A
chr7_+_142692165 0.496 NM_153345
TMEM139
transmembrane protein 139
chr12_-_46883341 0.490 NM_001004134
OR10AD1
olfactory receptor, family 10, subfamily AD, member 1
chr1_+_50348052 0.488 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_23965305 0.484 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr4_+_74488910 0.482 ALB
albumin
chr8_-_110730183 0.478 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr1_+_47305633 0.472 NM_178134
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr5_-_79982584 0.472 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr6_+_50894397 0.465 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr17_-_59204622 0.464 CCDC47
coiled-coil domain containing 47
chr6_-_2785682 0.455 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr17_+_59205244 0.453


chr2_-_99472910 0.453 NM_001037872
NM_016316
REV1

REV1 homolog (S. cerevisiae)

chr4_+_74488947 0.453 ALB
albumin
chr7_+_143511480 0.448 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr2_-_178461710 0.443 NM_001077196
PDE11A
phosphodiesterase 11A
chr20_-_48980858 0.443 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chrX_-_131919896 0.414 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr1_+_40611955 0.411 NM_022733
SMAP2
small ArfGAP2
chr8_-_102287044 0.405 NM_001042511
ZNF706
zinc finger protein 706
chr20_+_33223434 0.405 NM_006404
PROCR
protein C receptor, endothelial
chr4_-_74307637 0.402 ANKRD17
ankyrin repeat domain 17
chr17_-_36559579 0.401 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr6_+_105511615 0.400 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr4_+_144477432 0.399 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr6_-_136888771 0.398 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr5_+_56507029 0.392 NM_001127235
GPBP1
GC-rich promoter binding protein 1
chr2_-_70901186 0.392 NM_173535
CLEC4F
C-type lectin domain family 4, member F
chr11_+_4799126 0.388 NM_001004753
OR51F2
olfactory receptor, family 51, subfamily F, member 2
chr10_+_18589589 0.380 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_-_134415311 0.375 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr4_+_119174947 0.373 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_-_54183833 0.370 NM_016126
HSPB11
heat shock protein family B (small), member 11
chrX_+_117992623 0.368 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr4_-_174774368 0.367 NM_006792
MORF4
mortality factor 4
chr14_-_76958984 0.366 NM_138791
NM_001113475
C14orf148

chromosome 14 open reading frame 148

chr17_+_55269974 0.361


chr5_-_32424444 0.353 ZFR
zinc finger RNA binding protein
chr11_+_123639909 0.348 NM_001005198
OR8G5
olfactory receptor, family 8, subfamily G, member 5
chr16_-_52094613 0.346 NM_001012398
NM_022476
AKTIP

AKT interacting protein

chr2_-_31491057 0.346 XDH
xanthine dehydrogenase
chr19_-_46080496 0.343 NM_000764
NM_030589
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr1_-_245763763 0.342 NM_198074
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr2_+_64540843 0.338 HSPC159
galectin-related protein
chrX_+_38548316 0.337 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr20_+_36643251 0.335 NM_001018082
ADIG
adipogenin
chr6_+_7347878 0.332 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr6_+_131936057 0.332 NM_000045
ARG1
arginase, liver
chrX_-_33139349 0.329 NM_004006
DMD
dystrophin
chr2_-_224611568 0.329 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr10_-_95350949 0.326 NM_006744
RBP4
retinol binding protein 4, plasma
chr4_-_69570919 0.321 NM_001076
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr3_-_159872960 0.316 NM_020169
LXN
latexin
chr3_+_190831909 0.312 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr1_+_40612016 0.309 SMAP2
small ArfGAP2
chr7_+_128802719 0.309 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr14_+_19285426 0.309 NM_172194
OR4Q3
olfactory receptor, family 4, subfamily Q, member 3
chr2_-_127817143 0.308 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr9_-_99746923 0.308 NM_018437
HEMGN
hemogen
chr9_-_103237851 0.307 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr10_+_4995597 0.307 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr17_-_70901303 0.306 GRB2
growth factor receptor-bound protein 2
chrX_-_131375217 0.305 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chrX_+_41191630 0.304 NM_022567
NYX
nyctalopin
chrX_+_38548394 0.303 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr12_-_44407515 0.302 LOC400027
hypothetical LOC400027
chr7_-_143597313 0.302 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr2_-_31491102 0.298 NM_000379
XDH
xanthine dehydrogenase
chr1_+_210805319 0.297 NM_001030287
ATF3
activating transcription factor 3
chr18_+_30875297 0.296 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr12_-_44407756 0.295 LOC400027
hypothetical LOC400027
chr13_+_96672705 0.294 MBNL2
muscleblind-like 2 (Drosophila)
chr4_-_153493133 0.288 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr4_+_88187215 0.283 AFF1
AF4/FMR2 family, member 1
chr16_+_74868676 0.280 NM_033401
CNTNAP4
contactin associated protein-like 4
chr2_-_86276102 0.278 IMMT
inner membrane protein, mitochondrial
chr17_-_60439764 0.276 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr16_-_54424517 0.276 NM_001025194
NM_001025195
NM_001266
CES1


carboxylesterase 1


chr8_-_102286695 0.276 ZNF706
zinc finger protein 706
chr22_-_15682555 0.275 NM_175878
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr6_+_101953389 0.275 GRIK2
glutamate receptor, ionotropic, kainate 2
chr7_-_141048358 0.270 NM_001080392
KIAA1147
KIAA1147
chrX_+_38548373 0.267 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr11_+_9552809 0.267 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr5_-_43593277 0.265 NM_183323
PAIP1
poly(A) binding protein interacting protein 1
chrX_+_38548016 0.265 NM_021242
MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr17_-_26665144 0.265 EVI2B
ecotropic viral integration site 2B
chr1_+_205328834 0.264 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr17_-_59204685 0.264 NM_020198
CCDC47
coiled-coil domain containing 47
chr22_-_27787793 0.261 NM_015370
C22orf31
chromosome 22 open reading frame 31
chr2_-_38379031 0.260 ATL2
atlastin GTPase 2
chr12_-_116283793 0.260 NM_000620
NOS1
nitric oxide synthase 1 (neuronal)
chr8_-_86441115 0.258 NM_001164830
CA1
carbonic anhydrase I
chr22_-_48865980 0.257 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr10_-_64698831 0.254 NM_004241
JMJD1C
jumonji domain containing 1C
chr12_-_68291208 0.253 NM_201550
LRRC10
leucine rich repeat containing 10
chr7_-_112515068 0.252 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr3_+_134976965 0.252 TF
transferrin
chr4_-_153820535 0.252 NM_152680
TMEM154
transmembrane protein 154
chr10_+_68355797 0.251 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr1_+_195213289 0.250 NM_030787
CFHR5
complement factor H-related 5
chr10_+_96512447 0.247 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr1_+_149165438 0.246 NM_001145415
NM_012432
SETDB1

SET domain, bifurcated 1

chr11_+_93394025 0.245 NM_001098672
HEPHL1
hephaestin-like 1
chr7_-_143085704 0.245 NM_178561
CTAGE6P
CTAGE family, member 6, pseudogene
chr1_+_7767300 0.244 NM_016831
PER3
period homolog 3 (Drosophila)
chr2_-_74606819 0.244 NM_133637
DQX1
DEAQ box RNA-dependent ATPase 1
chr2_+_113542017 0.244 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chr6_-_28429950 0.243 NM_145909
ZNF323
zinc finger protein 323
chr15_+_91244563 0.241 CHD2
chromodomain helicase DNA binding protein 2
chr2_+_87536174 0.236 NCRNA00152
non-protein coding RNA 152
chr8_-_17797127 0.236 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr2_-_86276015 0.236 IMMT
inner membrane protein, mitochondrial
chr7_-_31347032 0.232 NM_022728
NEUROD6
neurogenic differentiation 6
chr17_-_36074812 0.230 NM_152349
KRT222
keratin 222
chr15_-_53996597 0.229 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr10_-_104201234 0.227 NM_024886
C10orf95
chromosome 10 open reading frame 95
chr13_+_96672541 0.227 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr1_+_61697209 0.226 NFIA
nuclear factor I/A
chr17_-_38979178 0.221 NM_001079675
ETV4
ets variant 4
chr19_-_53841064 0.219 NM_001217
CA11
carbonic anhydrase XI
chr6_-_24597717 0.218 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr3_+_187813538 0.217 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr2_-_202811459 0.214 NM_001005781
NM_001005782
NM_003352
SUMO1


SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)


chrX_-_118583346 0.212 NM_001170569
CXorf56
chromosome X open reading frame 56
chr2_+_132196533 0.211 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr12_+_109956210 0.211 NM_015267
CUX2
cut-like homeobox 2
chr2_+_161701711 0.208 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr6_+_158654890 0.208


chr12_-_73889777 0.207 NM_139136
NM_139137
NM_153748
KCNC2


potassium voltage-gated channel, Shaw-related subfamily, member 2


chr6_-_132073849 0.205 NM_001145659
CTAGE9
CTAGE family, member 9
chr7_+_80105907 0.204 CD36
CD36 molecule (thrombospondin receptor)
chr5_-_137876416 0.204 ETF1
eukaryotic translation termination factor 1
chr18_+_19286784 0.202 NM_003831
RIOK3
RIO kinase 3 (yeast)
chr14_+_101345878 0.199 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr9_+_71009746 0.199 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr1_-_6218554 0.193 ICMT
isoprenylcysteine carboxyl methyltransferase
chr4_-_176970895 0.192 GPM6A
glycoprotein M6A
chr17_-_38978772 0.192 NM_001986
ETV4
ets variant 4
chr7_-_112515035 0.191 GPR85
G protein-coupled receptor 85
chr3_-_195670256 0.191 NM_024524
ATP13A3
ATPase type 13A3
chr19_-_40684638 0.190 NM_001035516
DMKN
dermokine
chr1_+_151081953 0.190 NM_001128600
LCE6A
late cornified envelope 6A
chr21_-_30836051 0.188 NM_181612
KRTAP19-6
keratin associated protein 19-6
chrX_-_84521052 0.187 POF1B
premature ovarian failure, 1B
chrX_-_118583401 0.186 NM_001170570
NM_022101
CXorf56

chromosome X open reading frame 56

chr1_-_6218576 0.185 ICMT
isoprenylcysteine carboxyl methyltransferase
chr4_+_74488835 0.185 NM_000477
ALB
albumin
chr21_-_14840506 0.184 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr19_+_56671649 0.184 NM_001080405
CEACAM18
carcinoembryonic antigen-related cell adhesion molecule 18
chr21_+_37714470 0.183 NM_130438
NM_001396
DYRK1A

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

chr19_-_6410735 0.180 NM_024103
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr16_+_76613912 0.180 NM_005752
CLEC3A
C-type lectin domain family 3, member A
chr9_+_96561750 0.180 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr1_-_150599105 0.179 NM_001014342
FLG2
filaggrin family member 2
chr10_-_69267774 0.177 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr6_-_133076873 0.177 NM_004666
VNN1
vanin 1
chr12_-_28016182 0.177 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr8_-_91066060 0.175 NM_002485
NBN
nibrin
chr2_-_88208650 0.175 NM_001443
FABP1
fatty acid binding protein 1, liver
chr22_+_38627031 0.172 NM_004810
GRAP2
GRB2-related adaptor protein 2
chr13_-_99983945 0.170 NM_033110
A2LD1
AIG2-like domain 1
chr2_-_86276403 0.169 NM_001100169
NM_001100170
NM_006839
IMMT


inner membrane protein, mitochondrial


chr11_+_65026382 0.168


chr10_-_69125932 0.167 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr22_+_20252020 0.167 UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr16_-_54424473 0.166 CES1
carboxylesterase 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
37.01 1.68e-04 GO:0047023 androsterone dehydrogenase activity
9.25 1.06e-02 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
27.76 2.47e-02 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
7.93 2.71e-02 GO:0016229 steroid dehydrogenase activity