Motif ID: PAX3,7.p2

Z-value: 0.131


Transcription factors associated with PAX3,7.p2:

Gene SymbolEntrez IDGene Name
PAX3 5077 paired box 3
PAX7 5081 paired box 7

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX3chr2_-_2228671710.467.7e-02Click!
PAX7chr1_+_188300860.214.3e-01Click!


Activity profile for motif PAX3,7.p2.

activity profile for motif PAX3,7.p2


Sorted Z-values histogram for motif PAX3,7.p2

Sorted Z-values for motif PAX3,7.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX3,7.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_57385140 0.079 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr19_+_57385130 0.076 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr19_+_57385041 0.068 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr19_+_57385146 0.063 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr19_+_57385072 0.053 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr4_+_9094611 0.044 NM_001040071
LOC650293
seven transmembrane helix receptor
chr12_+_6930778 0.030 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr19_-_54857003 0.030 IRF3
interferon regulatory factor 3
chr19_+_57384866 0.028 NM_014225
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr12_+_6930799 0.027 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr14_+_23654161 0.026 DCAF11
DDB1 and CUL4 associated factor 11
chr12_+_6930792 0.025 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_6930804 0.025 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr10_+_91077581 0.022 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr15_-_81412354 0.020 NM_004839
NM_199330
NM_199331
NM_199332
HOMER2



homer homolog 2 (Drosophila)



chr12_+_6930694 0.018 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr12_+_6930815 0.014 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr8_-_71146103 0.013 NM_024504
PRDM14
PR domain containing 14
chr10_-_126422774 0.011 FAM53B
family with sequence similarity 53, member B
chr17_-_36792161 0.007 NM_021013
KRT34
keratin 34

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
82.48 3.92e-04 GO:0060337 type I interferon-mediated signaling pathway
82.48 3.92e-04 GO:0071357 cellular response to type I interferon
81.17 4.12e-04 GO:0034340 response to type I interferon
309.65 1.40e-03 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
27.86 1.03e-02 GO:0019221 cytokine-mediated signaling pathway
25.14 1.39e-02 GO:0071345 cellular response to cytokine stimulus
68.20 3.08e-02 GO:0001933 negative regulation of protein phosphorylation
18.15 3.65e-02 GO:0034097 response to cytokine stimulus
55.02 4.73e-02 GO:0060333 interferon-gamma-mediated signaling pathway

Nothing significant found in compartment category.

Nothing significant found in function category.