Motif ID: PAX5.p2

Z-value: 1.996


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_37024358-0.467.0e-02Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_133923992 2.568 NPHP3-ACAD11
NPHP3-ACAD11 read-through transcript
chr3_-_133923906 2.346 NM_153240
NPHP3
nephronophthisis 3 (adolescent)
chr19_+_61742111 1.987 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr17_-_78199384 1.297 NM_019613
WDR45L
WDR45-like
chr14_-_52487558 1.279 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr2_+_235525355 1.248 NM_014521
SH3BP4
SH3-domain binding protein 4
chr1_+_24944554 1.135 CLIC4
chloride intracellular channel 4
chr2_-_98713862 1.124 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_-_179024002 1.057 NM_003690
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr3_-_69212192 1.054 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr2_-_98714020 1.054 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr16_-_52094613 1.041 NM_001012398
NM_022476
AKTIP

AKT interacting protein

chr13_+_27094018 1.033 POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr1_-_109386112 1.015 NM_001142550
NM_001142551
NM_014969
WDR47


WD repeat domain 47


chrX_+_18353623 1.002 NM_003159
CDKL5
cyclin-dependent kinase-like 5
chr14_-_52487386 0.981 FERMT2
fermitin family member 2
chr6_-_109911125 0.973 NM_001164313
NM_014797
ZBTB24

zinc finger and BTB domain containing 24

chr20_-_3336586 0.961 C20orf194
chromosome 20 open reading frame 194
chr2_-_215382537 0.955 NM_000465
BARD1
BRCA1 associated RING domain 1
chr16_-_3225360 0.922 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr1_+_24944493 0.908 CLIC4
chloride intracellular channel 4
chr2_+_56264627 0.898 NM_001080433
CCDC85A
coiled-coil domain containing 85A
chr18_+_11971443 0.892 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr1_+_113734997 0.870 NM_001142782
NM_152900
MAGI3

membrane associated guanylate kinase, WW and PDZ domain containing 3

chr18_+_11971421 0.867 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr6_-_109911015 0.852 ZBTB24
zinc finger and BTB domain containing 24
chr6_+_132170847 0.841 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr3_-_127677451 0.838 NM_001040653
NM_025112
ZXDC

ZXD family zinc finger C

chr8_+_25098296 0.831 DOCK5
dedicator of cytokinesis 5
chr12_-_13044448 0.830 HEBP1
heme binding protein 1
chr12_-_13044314 0.829 HEBP1
heme binding protein 1
chr8_+_25098171 0.828 NM_024940
DOCK5
dedicator of cytokinesis 5
chr9_-_36391149 0.825 NM_194330
RNF38
ring finger protein 38
chr20_-_51644187 0.818 ZNF217
zinc finger protein 217
chr12_-_13044467 0.815 NM_015987
HEBP1
heme binding protein 1
chr11_+_101485946 0.808 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr6_-_99502528 0.796 NM_012160
FBXL4
F-box and leucine-rich repeat protein 4
chr10_-_12124778 0.795 NM_015542
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr4_-_108860740 0.791 NM_005443
PAPSS1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr2_+_233270286 0.789 GIGYF2
GRB10 interacting GYF protein 2
chr10_+_171410 0.781 ZMYND11
zinc finger, MYND-type containing 11
chr17_+_26060617 0.778


chr9_-_33157300 0.769 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr1_-_115433570 0.766 NM_005725
TSPAN2
tetraspanin 2
chr1_-_93919789 0.764 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr2_-_11402150 0.762 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr10_-_35143900 0.754 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr14_+_103251798 0.754 NM_001198953
NM_024071
ZFYVE21

zinc finger, FYVE domain containing 21

chr3_-_198509276 0.749 DLG1
discs, large homolog 1 (Drosophila)
chr13_+_26029879 0.749 WASF3
WAS protein family, member 3
chr1_+_181259317 0.746


chr12_-_74711642 0.735 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr3_-_151171190 0.735 NM_002628
NM_053024
PFN2

profilin 2

chr8_-_99906944 0.732 NM_006281
STK3
serine/threonine kinase 3
chr16_+_67131161 0.732 NM_133458
ZFP90
zinc finger protein 90 homolog (mouse)
chr8_-_67687980 0.729 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

hypothetical LOC645895
chr2_+_238265519 0.728 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr21_+_45318861 0.717 NM_001112
NM_001160230
NM_015833
NM_015834
ADARB1



adenosine deaminase, RNA-specific, B1



chr2_+_24126140 0.713 FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr16_+_67130616 0.691 ZFP90
zinc finger protein 90 homolog (mouse)
chr1_+_24944346 0.688 NM_013943
CLIC4
chloride intracellular channel 4
chr13_+_43351968 0.688 NM_153218
C13orf31
chromosome 13 open reading frame 31
chr17_+_75849221 0.683 NM_020914
NM_020954
RNF213

ring finger protein 213

chr1_-_233879617 0.682 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr1_+_86943103 0.673 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr7_-_28186671 0.670 JAZF1
JAZF zinc finger 1
chr10_-_15250616 0.661 NM_004808
NMT2
N-myristoyltransferase 2
chr18_+_54489763 0.647 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr11_+_109468734 0.645 ZC3H12C
zinc finger CCCH-type containing 12C
chr1_+_86943074 0.645 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr13_-_113066366 0.644 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr10_-_62431203 0.639 RHOBTB1
Rho-related BTB domain containing 1
chr18_+_11971552 0.636 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr14_-_50367513 0.634 NM_016350
NM_020921
NM_182944
NM_182946
NIN



ninein (GSK3B interacting protein)



chr5_+_135392482 0.634 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr9_+_96807107 0.634 C9orf3
chromosome 9 open reading frame 3
chr13_+_97426713 0.632 IPO5
importin 5
chr3_+_32255158 0.627 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr4_-_158111995 0.626 NM_016205
PDGFC
platelet derived growth factor C
chr3_-_187025501 0.625 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr8_-_13035102 0.624 NM_006094
DLC1
deleted in liver cancer 1
chr10_-_135036805 0.620 NM_004092
ECHS1
enoyl CoA hydratase, short chain, 1, mitochondrial
chr13_-_43351825 0.620 NM_144974
CCDC122
coiled-coil domain containing 122
chr16_-_56789142 0.617 NM_001896
CSNK2A2
casein kinase 2, alpha prime polypeptide
chr18_+_53862744 0.608 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr2_-_177837540 0.603 NFE2L2
nuclear factor (erythroid-derived 2)-like 2
chr18_+_9126742 0.593 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr2_-_99472843 0.592 REV1
REV1 homolog (S. cerevisiae)
chr5_+_122138677 0.592 SNX2
sorting nexin 2
chr10_+_124124083 0.589 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_-_23683214 0.587 ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr21_+_46473494 0.585 MCM3AP-AS1
MCM3AP antisense RNA 1 (non-protein coding)
chr20_-_23566325 0.579 NM_000099
CST3
cystatin C
chr5_-_114660139 0.579 NM_001040440
CCDC112
coiled-coil domain containing 112
chr1_-_23683308 0.578 NM_001143778
NM_017707
ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

chr2_-_158440587 0.577 NM_001111067
ACVR1
activin A receptor, type I
chr7_-_105712565 0.576 NAMPT
nicotinamide phosphoribosyltransferase
chr2_+_219354948 0.575 CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr2_+_112529270 0.573 NM_032824
TMEM87B
transmembrane protein 87B
chr6_-_114398946 0.573 HDAC2
histone deacetylase 2
chr15_-_27901828 0.569 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr17_-_15407497 0.568 NM_001135036
NM_145301
FAM18B2-CDRT4
FAM18B2

FAM18B2-CDRT4 read-through transcript
family with sequence similarity 18, member B2

chr5_+_122138661 0.568 SNX2
sorting nexin 2
chr13_-_27092677 0.568 NM_153371
LNX2
ligand of numb-protein X 2
chr5_+_122138636 0.566 NM_003100
SNX2
sorting nexin 2
chr14_+_55116549 0.565 NM_001079521
NM_001079522
NM_004986
NM_182926
KTN1



kinectin 1 (kinesin receptor)



chrX_+_17665483 0.562 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr7_+_115926855 0.562 CAV2
caveolin 2
chrX_-_132947141 0.561 GPC3
glypican 3
chr13_-_113066202 0.560 GRTP1
growth hormone regulated TBC protein 1
chr18_+_12937972 0.560 NM_001013437
NM_031216
SEH1L

SEH1-like (S. cerevisiae)

chr13_+_27094024 0.557 NM_015972
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr9_+_494661 0.555 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr6_+_17389752 0.549 NM_001143942
RBM24
RNA binding motif protein 24
chr4_+_3264509 0.548 RGS12
regulator of G-protein signaling 12
chr1_+_86942874 0.547 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr2_-_179023600 0.547 NM_001139518
NM_001139517
PRKRA

protein kinase, interferon-inducible double stranded RNA dependent activator

chr6_+_132170888 0.546 ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr20_-_39680405 0.546 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr3_-_187025438 0.543 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr15_+_54998144 0.542 TCF12
transcription factor 12
chr6_-_99502495 0.538 FBXL4
F-box and leucine-rich repeat protein 4
chr17_-_74432800 0.535 TIMP2
TIMP metallopeptidase inhibitor 2
chr7_-_107883929 0.535 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr1_+_9275542 0.534 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr3_-_151171576 0.533 PFN2
profilin 2
chr13_+_26029799 0.533 NM_006646
WASF3
WAS protein family, member 3
chr18_+_27925923 0.533 RNF138
ring finger protein 138
chr2_-_114230455 0.530 SLC35F5
solute carrier family 35, member F5
chr8_-_71478041 0.530 NCOA2
nuclear receptor coactivator 2
chr6_-_13819463 0.529 RANBP9
RAN binding protein 9
chr6_-_101435727 0.529 ASCC3
activating signal cointegrator 1 complex subunit 3
chr18_+_12938010 0.527 SEH1L
SEH1-like (S. cerevisiae)
chr2_-_97572580 0.526


chr12_-_93568336 0.523 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr14_+_102128844 0.523 NM_015156
RCOR1
REST corepressor 1
chr15_-_53667800 0.521 PYGO1
pygopus homolog 1 (Drosophila)
chr4_-_170428564 0.520 SH3RF1
SH3 domain containing ring finger 1
chr3_-_123716471 0.518 NM_002264
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr2_+_10101081 0.518 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr2_-_16710551 0.514 NM_030797
FAM49A
family with sequence similarity 49, member A
chr8_+_38208165 0.514 NM_001164234
NM_015214
DDHD2

DDHD domain containing 2

chr6_+_160068553 0.513 WTAP
Wilms tumor 1 associated protein
chr17_-_72218535 0.511 NM_001008528
NM_001008529
NM_198530
MXRA7


matrix-remodelling associated 7


chr20_-_55718351 0.511 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_-_171814026 0.510 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr4_-_102487649 0.509 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr13_+_110565587 0.509 NM_001113511
NM_001113512
NM_145735
ARHGEF7


Rho guanine nucleotide exchange factor (GEF) 7


chr18_+_54489798 0.509 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr2_-_95188989 0.509 NM_032788
ZNF514
zinc finger protein 514
chr3_-_127677400 0.508 ZXDC
ZXD family zinc finger C
chr4_-_37364327 0.507 NM_001085399
NM_001085400
RELL1

RELT-like 1

chr1_+_9275518 0.506 NM_025106
SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr15_-_50375143 0.503 NM_018728
MYO5C
myosin VC
chr6_-_119297851 0.502 MCM9
minichromosome maintenance complex component 9
chr17_-_60088773 0.500 NM_022739
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr18_-_43711143 0.498 SMAD2
SMAD family member 2
chr2_+_61146542 0.497 KIAA1841
KIAA1841
chr8_-_102287083 0.497 NM_001042510
NM_016096
ZNF706

zinc finger protein 706

chr16_-_79687367 0.494 NM_004483
GCSH
glycine cleavage system protein H (aminomethyl carrier)
chr12_-_74711474 0.489 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr14_-_52232316 0.486 ERO1L
ERO1-like (S. cerevisiae)
chr4_-_177950658 0.485 NM_005429
VEGFC
vascular endothelial growth factor C
chr3_+_171558188 0.484 SKIL
SKI-like oncogene
chr14_-_38971370 0.481 NM_203301
FBXO33
F-box protein 33
chr5_+_79986254 0.479 MSH3
mutS homolog 3 (E. coli)
chr11_-_86343859 0.479 NM_012193
FZD4
frizzled homolog 4 (Drosophila)
chr2_-_25328452 0.478 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr2_+_238265617 0.477 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr14_+_56927014 0.477 NM_001011713
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr6_+_142664490 0.476 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr4_+_99401543 0.476 NM_001100426
NM_001100427
NM_001100428
NM_001100429
NM_001100430
NM_021159
RAP1GDS1





RAP1, GTP-GDP dissociation stimulator 1





chr3_+_23961739 0.476 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr12_-_103055924 0.476 NM_006166
NFYB
nuclear transcription factor Y, beta
chr12_+_102982365 0.476 NM_013320
HCFC2
host cell factor C2
chr20_+_60130963 0.474 LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chr14_+_99329198 0.474 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr18_+_53862386 0.472 NM_001144967
NM_015277
NEDD4L

neural precursor cell expressed, developmentally down-regulated 4-like

chr7_+_77004267 0.471 PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr11_-_72170533 0.470 STARD10
StAR-related lipid transfer (START) domain containing 10
chr6_+_160068531 0.470 WTAP
Wilms tumor 1 associated protein
chr12_+_3056781 0.469 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr6_+_117910472 0.469 NM_173674
DCBLD1
discoidin, CUB and LCCL domain containing 1
chr2_-_97978421 0.466 NM_015348
TMEM131
transmembrane protein 131
chr3_+_171558215 0.466 SKIL
SKI-like oncogene
chr13_+_95002942 0.465 NM_006984
CLDN10
claudin 10
chr4_-_53220073 0.463 NM_022832
USP46
ubiquitin specific peptidase 46
chr1_-_93199586 0.462 NM_001006605
FAM69A
family with sequence similarity 69, member A
chr15_-_20637731 0.462 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr8_-_131021169 0.462 NM_016623
FAM49B
family with sequence similarity 49, member B
chr8_-_131021078 0.461 FAM49B
family with sequence similarity 49, member B
chr10_+_124124196 0.461 PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr6_+_160068598 0.459 NM_152857
WTAP
Wilms tumor 1 associated protein
chr18_+_54489658 0.459 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr1_+_70459686 0.458 SRSF11
serine/arginine-rich splicing factor 11
chr12_+_2938703 0.457 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr7_+_55054152 0.456 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr10_+_121475628 0.455 INPP5F
inositol polyphosphate-5-phosphatase F
chr18_-_63334902 0.454 NM_032160
DSEL
dermatan sulfate epimerase-like
chr12_+_67290881 0.454 NM_001010942
NM_015646
RAP1B

RAP1B, member of RAS oncogene family


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 2.32e-31 GO:0044237 cellular metabolic process
1.23 3.86e-28 GO:0044260 cellular macromolecule metabolic process
1.17 5.63e-25 GO:0044238 primary metabolic process
1.15 3.05e-24 GO:0008152 metabolic process
1.09 8.34e-24 GO:0009987 cellular process
1.19 6.96e-22 GO:0043170 macromolecule metabolic process
1.34 1.22e-20 GO:0006464 protein modification process
1.32 1.30e-19 GO:0043412 macromolecule modification
1.27 7.08e-19 GO:0044267 cellular protein metabolic process
1.12 2.24e-13 GO:0050794 regulation of cellular process
1.21 2.95e-13 GO:0019538 protein metabolic process
1.11 8.56e-13 GO:0050789 regulation of biological process
1.10 1.61e-12 GO:0065007 biological regulation
1.30 4.34e-11 GO:0009966 regulation of signal transduction
1.24 4.64e-11 GO:0048523 negative regulation of cellular process
1.34 3.98e-10 GO:0006793 phosphorus metabolic process
1.34 3.98e-10 GO:0006796 phosphate metabolic process
1.20 6.58e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 1.01e-09 GO:0016043 cellular component organization
1.31 1.22e-09 GO:0044248 cellular catabolic process
1.18 2.40e-09 GO:0034641 cellular nitrogen compound metabolic process
1.16 3.43e-09 GO:0071840 cellular component organization or biogenesis
1.17 5.63e-09 GO:0006807 nitrogen compound metabolic process
1.25 8.51e-09 GO:0023051 regulation of signaling
1.26 1.75e-08 GO:0009056 catabolic process
1.40 2.91e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.14 4.50e-08 GO:0019222 regulation of metabolic process
1.20 5.02e-08 GO:0048519 negative regulation of biological process
1.24 1.02e-07 GO:0006996 organelle organization
1.34 3.38e-07 GO:0046907 intracellular transport
1.30 3.64e-07 GO:0007049 cell cycle
1.18 3.82e-07 GO:0071842 cellular component organization at cellular level
1.26 4.11e-07 GO:0051641 cellular localization
1.15 4.30e-07 GO:0060255 regulation of macromolecule metabolic process
1.42 4.35e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.15 5.27e-07 GO:0031323 regulation of cellular metabolic process
1.17 8.17e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.19 8.31e-07 GO:0090304 nucleic acid metabolic process
1.14 2.10e-06 GO:0080090 regulation of primary metabolic process
1.25 2.86e-06 GO:0033036 macromolecule localization
1.27 4.47e-06 GO:0051246 regulation of protein metabolic process
1.36 5.91e-06 GO:0009057 macromolecule catabolic process
1.39 7.00e-06 GO:0044265 cellular macromolecule catabolic process
1.12 8.42e-06 GO:0051716 cellular response to stimulus
1.73 9.72e-06 GO:0016311 dephosphorylation
1.32 1.02e-05 GO:0006468 protein phosphorylation
1.27 1.50e-05 GO:0032268 regulation of cellular protein metabolic process
1.46 1.62e-05 GO:0018193 peptidyl-amino acid modification
1.17 1.85e-05 GO:0048522 positive regulation of cellular process
1.26 2.26e-05 GO:0008104 protein localization
1.26 3.06e-05 GO:0043067 regulation of programmed cell death
1.26 4.03e-05 GO:0010941 regulation of cell death
1.26 6.72e-05 GO:0042981 regulation of apoptosis
1.16 6.93e-05 GO:0044249 cellular biosynthetic process
1.24 8.00e-05 GO:0051649 establishment of localization in cell
1.72 8.05e-05 GO:0006470 protein dephosphorylation
1.29 9.35e-05 GO:0051128 regulation of cellular component organization
1.15 1.10e-04 GO:0048518 positive regulation of biological process
1.15 1.20e-04 GO:0009058 biosynthetic process
1.21 1.33e-04 GO:0065009 regulation of molecular function
1.29 1.55e-04 GO:0031399 regulation of protein modification process
1.28 2.19e-04 GO:0016310 phosphorylation
1.61 2.51e-04 GO:0051493 regulation of cytoskeleton organization
1.27 2.67e-04 GO:0033554 cellular response to stress
1.27 2.80e-04 GO:0045184 establishment of protein localization
1.29 3.38e-04 GO:0016192 vesicle-mediated transport
1.26 4.21e-04 GO:0016265 death
1.26 5.11e-04 GO:0008219 cell death
1.12 5.73e-04 GO:0007165 signal transduction
1.18 6.03e-04 GO:0034645 cellular macromolecule biosynthetic process
1.17 6.83e-04 GO:0048583 regulation of response to stimulus
1.26 8.26e-04 GO:0015031 protein transport
1.51 8.26e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.43 8.28e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.18 9.67e-04 GO:0009059 macromolecule biosynthetic process
1.56 1.12e-03 GO:0051169 nuclear transport
1.28 1.13e-03 GO:0012501 programmed cell death
1.56 1.25e-03 GO:0006913 nucleocytoplasmic transport
1.30 1.32e-03 GO:0051726 regulation of cell cycle
1.11 1.32e-03 GO:0023052 signaling
1.41 1.66e-03 GO:0044257 cellular protein catabolic process
1.33 1.80e-03 GO:0034613 cellular protein localization
1.32 1.96e-03 GO:0070727 cellular macromolecule localization
1.28 2.13e-03 GO:0019220 regulation of phosphate metabolic process
1.28 2.13e-03 GO:0051174 regulation of phosphorus metabolic process
1.40 2.33e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
1.20 2.41e-03 GO:0035556 intracellular signal transduction
1.17 3.16e-03 GO:0016070 RNA metabolic process
1.61 3.22e-03 GO:0051099 positive regulation of binding
1.40 3.28e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.40 3.68e-03 GO:0019941 modification-dependent protein catabolic process
1.27 4.24e-03 GO:0006915 apoptosis
1.25 4.32e-03 GO:0022402 cell cycle process
1.38 4.79e-03 GO:0030163 protein catabolic process
1.32 4.95e-03 GO:0051338 regulation of transferase activity
1.28 6.26e-03 GO:0001932 regulation of protein phosphorylation
1.39 7.45e-03 GO:0033043 regulation of organelle organization
1.34 8.80e-03 GO:0043066 negative regulation of apoptosis
1.33 1.01e-02 GO:0060548 negative regulation of cell death
1.31 1.14e-02 GO:0043549 regulation of kinase activity
1.33 1.17e-02 GO:0043069 negative regulation of programmed cell death
1.28 1.40e-02 GO:0000278 mitotic cell cycle
1.26 1.76e-02 GO:0042325 regulation of phosphorylation
1.40 1.77e-02 GO:0032446 protein modification by small protein conjugation
1.34 1.80e-02 GO:0006886 intracellular protein transport
1.37 1.82e-02 GO:0070647 protein modification by small protein conjugation or removal
1.31 1.83e-02 GO:0045859 regulation of protein kinase activity
1.29 2.01e-02 GO:0010942 positive regulation of cell death
1.37 2.29e-02 GO:0051098 regulation of binding
1.25 2.31e-02 GO:0022403 cell cycle phase
1.12 2.42e-02 GO:0010468 regulation of gene expression
1.20 2.51e-02 GO:0010646 regulation of cell communication
1.22 2.58e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.35 2.72e-02 GO:0051301 cell division
1.20 2.73e-02 GO:0022607 cellular component assembly
2.61 2.95e-02 GO:0048008 platelet-derived growth factor receptor signaling pathway
1.29 3.01e-02 GO:0043068 positive regulation of programmed cell death
1.19 3.27e-02 GO:0050790 regulation of catalytic activity
1.59 3.32e-02 GO:0043388 positive regulation of DNA binding
1.89 3.41e-02 GO:0046519 sphingoid metabolic process
1.21 3.52e-02 GO:0009892 negative regulation of metabolic process
1.12 3.61e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.12 3.66e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 3.96e-02 GO:0016568 chromatin modification
1.34 4.03e-02 GO:0044419 interspecies interaction between organisms
1.18 4.19e-02 GO:0044085 cellular component biogenesis
1.10 4.55e-02 GO:0051179 localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 6.53e-55 GO:0005622 intracellular
1.13 3.04e-54 GO:0044424 intracellular part
1.17 1.29e-42 GO:0005737 cytoplasm
1.16 6.49e-42 GO:0043227 membrane-bounded organelle
1.15 1.59e-41 GO:0043231 intracellular membrane-bounded organelle
1.14 1.08e-40 GO:0043226 organelle
1.14 1.47e-40 GO:0043229 intracellular organelle
1.20 5.78e-34 GO:0044444 cytoplasmic part
1.19 5.24e-27 GO:0005634 nucleus
1.31 1.13e-20 GO:0005829 cytosol
1.15 2.99e-16 GO:0044422 organelle part
1.14 1.24e-15 GO:0044446 intracellular organelle part
1.24 1.39e-12 GO:0044428 nuclear part
1.03 1.31e-11 GO:0044464 cell part
1.03 1.48e-11 GO:0005623 cell
1.21 3.86e-10 GO:0070013 intracellular organelle lumen
1.20 8.71e-10 GO:0031974 membrane-enclosed lumen
1.20 1.80e-09 GO:0043233 organelle lumen
1.22 1.12e-08 GO:0031981 nuclear lumen
1.26 2.70e-08 GO:0005654 nucleoplasm
1.67 3.86e-07 GO:0031252 cell leading edge
1.21 7.41e-07 GO:0012505 endomembrane system
1.70 1.64e-06 GO:0005912 adherens junction
1.65 5.08e-06 GO:0070161 anchoring junction
1.25 1.36e-05 GO:0005794 Golgi apparatus
1.29 2.51e-05 GO:0044451 nucleoplasm part
1.41 4.51e-05 GO:0048471 perinuclear region of cytoplasm
1.16 4.67e-05 GO:0031090 organelle membrane
1.29 8.49e-05 GO:0015630 microtubule cytoskeleton
1.72 1.32e-04 GO:0030055 cell-substrate junction
1.73 3.29e-04 GO:0005925 focal adhesion
1.46 3.64e-04 GO:0005635 nuclear envelope
1.70 4.37e-04 GO:0005924 cell-substrate adherens junction
1.12 1.11e-03 GO:0043234 protein complex
1.37 1.41e-03 GO:0005815 microtubule organizing center
1.44 2.24e-03 GO:0005813 centrosome
1.12 3.93e-03 GO:0043228 non-membrane-bounded organelle
1.12 3.93e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.16 4.46e-03 GO:0005856 cytoskeleton
1.26 5.55e-03 GO:0044431 Golgi apparatus part
1.29 7.53e-03 GO:0000139 Golgi membrane
1.23 8.13e-03 GO:0031967 organelle envelope
1.17 8.15e-03 GO:0005739 mitochondrion
1.23 9.71e-03 GO:0031975 envelope
1.25 1.03e-02 GO:0030054 cell junction
1.39 1.66e-02 GO:0016323 basolateral plasma membrane
1.65 2.15e-02 GO:0030027 lamellipodium
1.64 3.61e-02 GO:0046930 pore complex
1.61 3.86e-02 GO:0016585 chromatin remodeling complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 7.09e-31 GO:0005515 protein binding
1.08 1.69e-25 GO:0005488 binding
1.12 4.67e-10 GO:0003824 catalytic activity
1.21 5.66e-10 GO:0000166 nucleotide binding
1.32 2.97e-08 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.46 3.36e-08 GO:0019904 protein domain specific binding
1.34 4.71e-08 GO:0016301 kinase activity
1.21 9.91e-08 GO:0035639 purine ribonucleoside triphosphate binding
1.21 1.14e-07 GO:0017076 purine nucleotide binding
1.21 1.26e-07 GO:0032553 ribonucleotide binding
1.21 1.26e-07 GO:0032555 purine ribonucleotide binding
1.34 1.76e-07 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.44 2.62e-07 GO:0004674 protein serine/threonine kinase activity
1.22 3.88e-07 GO:0030554 adenyl nucleotide binding
1.22 5.59e-07 GO:0032559 adenyl ribonucleotide binding
1.22 7.46e-07 GO:0005524 ATP binding
1.36 1.31e-06 GO:0004672 protein kinase activity
1.69 1.93e-06 GO:0004721 phosphoprotein phosphatase activity
1.20 6.68e-06 GO:0016740 transferase activity
1.39 6.89e-06 GO:0030695 GTPase regulator activity
1.37 1.91e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.49 2.69e-05 GO:0032403 protein complex binding
1.29 4.76e-05 GO:0019899 enzyme binding
1.48 1.75e-04 GO:0016791 phosphatase activity
1.38 2.27e-04 GO:0000988 protein binding transcription factor activity
1.38 2.27e-04 GO:0000989 transcription factor binding transcription factor activity
1.43 2.65e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.43 2.98e-04 GO:0008134 transcription factor binding
1.38 3.18e-04 GO:0003712 transcription cofactor activity
1.75 3.84e-04 GO:0004725 protein tyrosine phosphatase activity
1.26 5.69e-04 GO:0042802 identical protein binding
1.56 7.97e-04 GO:0000287 magnesium ion binding
1.38 9.76e-04 GO:0042578 phosphoric ester hydrolase activity
1.43 1.03e-03 GO:0016881 acid-amino acid ligase activity
1.22 1.64e-03 GO:0030234 enzyme regulator activity
1.54 2.21e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.31 3.35e-03 GO:0016874 ligase activity
1.32 3.41e-03 GO:0042803 protein homodimerization activity
1.38 7.36e-03 GO:0005083 small GTPase regulator activity
1.41 1.21e-02 GO:0019787 small conjugating protein ligase activity
1.25 1.28e-02 GO:0046983 protein dimerization activity
1.23 1.67e-02 GO:0016788 hydrolase activity, acting on ester bonds
1.55 2.74e-02 GO:0035091 phosphatidylinositol binding
1.38 4.43e-02 GO:0019900 kinase binding