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Motif ID: POU2F1..3.p2

Z-value: 1.987

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_23754772	6.703	NM_002738 NM_212535	PRKCB	protein kinase C, beta
chr16_+_23754822	5.439		PRKCB	protein kinase C, beta
chr16_+_23754860	5.290		PRKCB	protein kinase C, beta
chr14_-_106084519	5.066		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_+_23754997	4.439		PRKCB	protein kinase C, beta
chr6_+_26291936	4.146	NM_003523	HIST1H2BE	histone cluster 1, H2be
chr1_+_226712430	3.561	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr1_-_153098811	3.021	NM_170782	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_+_50318801	2.963		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr3_+_99733432	2.885	NM_005290	GPR15	G protein-coupled receptor 15
chr6_-_33016561	2.811	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr6_-_27968906	2.728	NM_003514	HIST1H2AM	histone cluster 1, H2am
chr22_+_21065134	2.638		LOC100290481	immunoglobulin lambda light chain-like
chr6_-_26151863	2.313	NM_021062	HIST1H2BB	histone cluster 1, H2bb
chr17_-_16816113	2.288	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr1_+_205736095	2.264	NM_000573 NM_000651	CR1	complement component (3b/4b) receptor 1 (Knops blood group)
chr10_+_124897627	1.957	NM_005519	HMX2	H6 family homeobox 2
chr6_-_26232109	1.913	NM_003526	HIST1H2BG HIST1H2BC	histone cluster 1, H2bg histone cluster 1, H2bc
chr22_+_20316968	1.910	NM_152612	CCDC116	coiled-coil domain containing 116
chr15_+_81906983	1.818	NM_003027	SH3GL3	SH3-domain GRB2-like 3
chr6_+_26266311	1.791	NM_021063 NM_138720	HIST1H2BD	histone cluster 1, H2bd
chr17_-_59363352	1.755	NM_000626 NM_001039933 NM_021602	CD79B	CD79b molecule, immunoglobulin-associated beta
chr12_+_56290229	1.737	NM_001111270	ARHGEF25	Rho guanine nucleotide exchange factor (GEF) 25
chr8_+_19840861	1.685	NM_000237	LPL	lipoprotein lipase
chr6_+_27222839	1.621	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr5_-_66528330	1.582	NM_005582	CD180	CD180 molecule
chr6_+_27969181	1.564	NM_003527	HIST1H2BO	histone cluster 1, H2bo
chr12_+_91620749	1.498	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr5_-_131907071	1.465	NM_000879	IL5	interleukin 5 (colony-stimulating factor, eosinophil)
chr9_-_126573349	1.436	NM_001489 NM_033334	NR6A1	nuclear receptor subfamily 6, group A, member 1
chr3_+_114733907	1.436	NM_017699	SIDT1	SID1 transmembrane family, member 1
chr22_+_21370394	1.397		IGL@	immunoglobulin lambda locus
chr12_-_10953427	1.381	NM_023920	TAS2R13	taste receptor, type 2, member 13
chr22_+_21042091	1.370		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr6_+_10693964	1.332	NM_145655	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr5_-_88155360	1.325	NM_001193348 NM_001193349	MEF2C	myocyte enhancer factor 2C
chr22_+_21094094	1.300
chr8_+_56954899	1.292	NM_001111097 NM_002350	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_+_26232351	1.290	NM_003512	HIST1H2AC	histone cluster 1, H2ac
chr19_+_14554895	1.263	NM_207390	CLEC17A	C-type lectin domain family 17, member A
chr15_+_81907176	1.258		SH3GL3	SH3-domain GRB2-like 3
chr6_-_26324850	1.249	NM_003518	HIST1H2BG NCALD	histone cluster 1, H2bg neurocalcin delta
chr16_-_87280380	1.248	NM_178310	SNAI3	snail homolog 3 (Drosophila)
chr19_-_18253413	1.234	NM_005354	JUND	jun D proto-oncogene
chr6_+_32515596	1.218	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr8_+_56954946	1.215		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr10_-_64246129	1.214	NM_000399 NM_001136177 NM_001136179	EGR2	early growth response 2
chr21_-_31123797	1.211	NM_181606	KRTAP7-1	keratin associated protein 7-1 (gene/pseudogene)
chr22_+_20880159	1.203		IGLV6-57	immunoglobulin lambda variable 6-57
chr13_-_45640679	1.189		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_27222556	1.182	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chr1_-_148124738	1.179	NM_003528	HIST2H2BE	histone cluster 2, H2be
chr10_-_64246080	1.167		EGR2	early growth response 2
chr6_+_27323458	1.158	NM_005865	PRSS16	protease, serine, 16 (thymus)
chr9_-_139316523	1.139	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr8_+_19841010	1.127		LPL	lipoprotein lipase
chr22_+_20715340	1.125
chr6_-_27208507	1.123	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr6_+_27208763	1.122	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr12_+_111829121	1.118	NM_001032409 NM_002534 NM_016816	OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa
chr6_+_25834983	1.074	NM_170610	HIST1H2BA	histone cluster 1, H2ba
chr6_-_27890496	1.068	NM_021066	HIST1H2AJ	histone cluster 1, H2aj
chr6_-_168219380	1.065	NM_001122841	FRMD1	FERM domain containing 1
chr1_+_202000906	1.064	NM_001136190 NM_017773	LAX1	lymphocyte transmembrane adaptor 1
chr1_+_148089251	1.059	NM_001040874 NM_003516	HIST2H2AA4 HIST2H2AA3	histone cluster 2, H2aa4 histone cluster 2, H2aa3
chr19_+_3523958	1.056		HMG20B	high-mobility group 20B
chr17_+_19999784	1.050	NM_001033554 NM_001033555	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1
chr17_-_44249379	1.049	NM_001130918	TTLL6	tubulin tyrosine ligase-like family, member 6
chr19_-_18253048	1.041		JUND	jun D proto-oncogene
chr6_+_135558572	1.038
chr15_+_76171981	1.032	NM_001101404	SH2D7	SH2 domain containing 7
chr10_-_98021144	1.031	NM_001114094 NM_013314	BLNK	B-cell linker
chr6_+_27941012	1.031	NM_003511	HIST1H2AI HIST1H2AL	histone cluster 1, H2ai histone cluster 1, H2al
chr19_+_60803412	1.031	NM_153219	ZNF524	zinc finger protein 524
chr14_-_105763152	1.028		IGHV4-31 IGHA1 IGHD IGHG1 IGHG3	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr22_+_21495273	1.020
chr1_+_5975286	1.018		KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr22_-_22426551	1.013	NM_013378	VPREB3	pre-B lymphocyte 3
chr1_+_5975345	1.009		KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr7_+_142629251	1.002	NM_176882	TAS2R40	taste receptor, type 2, member 40
chr19_-_51856129	0.982	NM_145056	DACT3	dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr6_+_37245860	0.978	NM_002648	PIM1	pim-1 oncogene
chr19_-_18369407	0.976	NM_145256	LRRC25	leucine rich repeat containing 25
chr5_-_176868483	0.953		DOK3	docking protein 3
chr6_+_26359805	0.950	NM_003524	HIST1H2BH	histone cluster 1, H2bh
chr6_+_27883877	0.943	NM_003509	HIST1H2AI HIST1H3F	histone cluster 1, H2ai histone cluster 1, H3f
chr2_-_2313894	0.935	NM_015025	MYT1L	myelin transcription factor 1-like
chr6_+_34312979	0.932		HMGA1	high mobility group AT-hook 1
chr22_+_20880112	0.931
chr22_+_44059491	0.927	NM_001167574 NM_006953	UPK3A	uroplakin 3A
chr2_+_96790298	0.927	NM_020184	CNNM4	cyclin M4
chr11_-_31789431	0.926	NM_000280 NM_001604	PAX6	paired box 6
chr22_+_31080871	0.925	NM_006604	RFPL3	ret finger protein-like 3
chr15_-_38953628	0.923	NM_133639	RHOV	ras homolog gene family, member V
chr14_-_106184988	0.920		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_80344096	0.903	NM_030763	HMGN5	high-mobility group nucleosome binding domain 5
chr1_-_148126089	0.898	NM_175065	HIST2H2AB HIST2H2BE	histone cluster 2, H2ab histone cluster 2, H2be
chr7_+_16759845	0.880	NM_014399	TSPAN13	tetraspanin 13
chrX_+_12903145	0.878	NM_021109 NM_183049	TMSB4X TMSL3	thymosin beta 4, X-linked thymosin-like 3
chr6_-_168222645	0.872	NM_024919	FRMD1	FERM domain containing 1
chr21_-_38415273	0.855	NM_005867	DSCR4	Down syndrome critical region gene 4
chr22_+_21407066	0.850
chr6_+_34312906	0.847		HMGA1	high mobility group AT-hook 1
chr19_+_17377502	0.842		LOC100507535	hypothetical LOC100507535
chr4_-_40212670	0.840	NM_019027	RBM47	RNA binding motif protein 47
chr2_-_157890400	0.840	NM_020711	ERMN	ermin, ERM-like protein
chr7_+_100021862	0.831	NM_033506	FBXO24	F-box protein 24
chr11_+_27019084	0.828	NM_003986	BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_-_87280289	0.827		SNAI3	snail homolog 3 (Drosophila)
chr3_+_153074118	0.823	NM_033050	SUCNR1	succinate receptor 1
chr2_-_219614481	0.817	NM_152389 NM_194302	CCDC108	coiled-coil domain containing 108
chr17_+_60563963	0.811		RGS9	regulator of G-protein signaling 9
chr6_+_26381122	0.804	NM_003525	HIST1H2BI	histone cluster 1, H2bi
chr14_-_105862080	0.802		IGHV4-31 IGHA1 IGHD IGHG1 IGHG2 IGHG3 IGHM SCFV	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu single-chain Fv fragment
chr3_+_188130967	0.795	NM_173216 NM_173217	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_+_97117144	0.795	NM_001170807 NM_020482	FHL5	four and a half LIM domains 5
chr8_+_56954953	0.782		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr11_-_558419	0.770
chr19_-_18253259	0.762
chr19_+_59820413	0.758	NM_006669	LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr8_+_19841209	0.755		LPL	lipoprotein lipase
chr19_+_3523950	0.754		HMG20B	high-mobility group 20B
chr6_+_34312667	0.752		HMGA1	high mobility group AT-hook 1
chr6_-_26141774	0.742	NM_003513	HIST1H2AB	histone cluster 1, H2ab
chr6_-_89984214	0.741	NM_002042	GABRR1	gamma-aminobutyric acid (GABA) receptor, rho 1
chr4_-_71751070	0.729		IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr12_+_111829191	0.704		OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa
chrX_+_37524250	0.704		CYBB	cytochrome b-245, beta polypeptide
chr19_-_19142053	0.703		MEF2B	myocyte enhancer factor 2B
chr8_+_19841120	0.699		LPL	lipoprotein lipase
chr17_-_44047299	0.695	NM_024016	HOXB8	homeobox B8
chr15_-_38387357	0.692		PLCB2	phospholipase C, beta 2
chr7_-_100021658	0.690		LRCH4	leucine-rich repeats and calponin homology (CH) domain containing 4
chr7_-_27206249	0.684	NM_000522	HOXA13	homeobox A13
chr2_-_238813365	0.683	NM_001142853 NM_018645	HES6	hairy and enhancer of split 6 (Drosophila)
chr12_-_8656705	0.675	NM_020661	AICDA	activation-induced cytidine deaminase
chr1_+_154386358	0.670	NM_001193301	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_+_129124591	0.670	NM_207335	KBTBD12	kelch repeat and BTB (POZ) domain containing 12
chr9_+_94766379	0.669		FGD3	FYVE, RhoGEF and PH domain containing 3
chr15_-_81037554	0.669	NM_001079533 NM_001079534 NM_001079535	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr14_-_106241445	0.669		IGHV4-31 IGHV1-69 IGHA1 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 1-69 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr16_+_28850760	0.668	NM_001178098 NM_001770	CD19	CD19 molecule
chr13_-_69580459	0.662	NM_020866	KLHL1	kelch-like 1 (Drosophila)
chr6_+_34313007	0.662		HMGA1	high mobility group AT-hook 1
chr3_-_193928038	0.653	NM_004113	FGF12	fibroblast growth factor 12
chr6_-_31668476	0.647	NM_001145466 NM_001145467 NM_147130	NCR3	natural cytotoxicity triggering receptor 3
chr12_-_68291208	0.643	NM_201550	LRRC10	leucine rich repeat containing 10
chr6_+_34312641	0.641		HMGA1	high mobility group AT-hook 1
chr11_-_113935789	0.640	NM_152315	FAM55A	family with sequence similarity 55, member A
chr15_-_38387410	0.636	NM_004573	PLCB2	phospholipase C, beta 2
chrX_+_37524190	0.629	NM_000397	CYBB	cytochrome b-245, beta polypeptide
chr2_-_238813284	0.629		HES6	hairy and enhancer of split 6 (Drosophila)
chr11_+_527521	0.623	NM_198075	LRRC56	leucine rich repeat containing 56
chr17_-_34635446	0.615	NM_198993	STAC2	SH3 and cysteine rich domain 2
chr1_+_165564904	0.612	NM_001198783	POU2F1	POU class 2 homeobox 1
chrX_-_84521398	0.610	NM_024921	POF1B	premature ovarian failure, 1B
chr18_-_22696532	0.609	NM_004028	AQP4	aquaporin 4
chr18_+_74841262	0.608	NM_171999	SALL3	sal-like 3 (Drosophila)
chr7_+_37746520	0.593	NM_181791	GPR141	G protein-coupled receptor 141
chr1_-_203579932	0.592		KLHDC8A	kelch domain containing 8A
chr17_-_33179118	0.591	NM_000458 NM_001165923	HNF1B	HNF1 homeobox B
chr1_+_204797079	0.589	NM_182665	RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr6_+_12825022	0.574		PHACTR1	phosphatase and actin regulator 1
chr6_-_99904251	0.573	NM_032511	C6orf168	chromosome 6 open reading frame 168
chr1_+_148125090	0.573	NM_003517	HIST2H2AC	histone cluster 2, H2ac
chr17_-_53849888	0.569		RNF43	ring finger protein 43
chr13_-_52320774	0.564	NM_002590 NM_032949	PCDH8	protocadherin 8
chr17_-_4792542	0.560	NM_005022	PFN1	profilin 1
chr17_-_36850978	0.559	NM_006771	KRT38	keratin 38
chr8_-_72437020	0.556	NM_000503	EYA1	eyes absent homolog 1 (Drosophila)
chr17_+_60563917	0.555	NM_001081955 NM_001165933 NM_003835	RGS9	regulator of G-protein signaling 9
chr3_+_120799411	0.549	NM_015900	PLA1A	phospholipase A1 member A
chrX_+_153767803	0.548	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated (intronic transcript) 2 coagulation factor VIII-associated (intronic transcript) 3 coagulation factor VIII-associated (intronic transcript) 1
chr7_-_44088608	0.540		POLM	polymerase (DNA directed), mu
chr5_+_2805261	0.536	NM_178569	C5orf38	chromosome 5 open reading frame 38
chr6_+_34312625	0.534	NM_145901 NM_145902	HMGA1	high mobility group AT-hook 1
chr1_+_204797120	0.528		RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr10_+_68355797	0.522	NM_178011	LRRTM3	leucine rich repeat transmembrane neuronal 3
chr8_-_25371663	0.521		KCTD9	potassium channel tetramerisation domain containing 9
chr3_-_167037861	0.519		BCHE	butyrylcholinesterase
chr11_-_117552545	0.517	NM_004588	SCN2B	sodium channel, voltage-gated, type II, beta
chr12_+_120548831	0.513	NM_032790	ORAI1	ORAI calcium release-activated calcium modulator 1
chr1_-_194844061	0.512	NM_198503	KCNT2	potassium channel, subfamily T, member 2
chr19_-_17377383	0.503	NM_004335	BST2	bone marrow stromal cell antigen 2
chr22_+_21384862	0.503		IGLV3-21 IGLJ3 IGLC1	immunoglobulin lambda variable 3-21 immunoglobulin lambda joining 3 immunoglobulin lambda constant 1 (Mcg marker)
chr14_+_22422270	0.502	NM_173527	REM2	RAS (RAD and GEM)-like GTP binding 2
chr22_-_14829803	0.502	NM_001005239	OR11H1	olfactory receptor, family 11, subfamily H, member 1
chr9_+_128716867	0.499	NM_001190729 NM_001190730 NM_014636	RALGPS1	Ral GEF with PH domain and SH3 binding motif 1
chr15_-_56145140	0.498	NM_003888 NM_170696	ALDH1A2	aldehyde dehydrogenase 1 family, member A2
chr3_+_63613383	0.497	NM_001080537	SNTN	sentan, cilia apical structure protein
chr14_-_105681377	0.494		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_63829616	0.488	NM_004451	ESRRA	estrogen-related receptor alpha
chr16_-_54466709	0.483	NM_001143685 NM_145024	CES5A	carboxylesterase 5A
chr2_-_51112743	0.481		NRXN1	neurexin 1
chr6_+_34312633	0.481		HMGA1	high mobility group AT-hook 1
chr22_+_21116283	0.477
chr6_+_34312554	0.476	NM_002131 NM_145899 NM_145903	HMGA1	high mobility group AT-hook 1
chr18_-_59462469	0.475	NM_002974	SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr3_-_167037946	0.473	NM_000055	BCHE	butyrylcholinesterase
chr2_-_104834344	0.466		LOC100506421	hypothetical LOC100506421

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
10.06	2.18e-16	GO:0006334	nucleosome assembly
9.44	2.76e-16	GO:0034728	nucleosome organization
9.55	9.35e-16	GO:0031497	chromatin assembly
8.60	3.76e-15	GO:0071824	protein-DNA complex subunit organization
7.62	7.28e-15	GO:0006333	chromatin assembly or disassembly
8.75	1.02e-14	GO:0065004	protein-DNA complex assembly
7.31	1.14e-12	GO:0006323	DNA packaging
6.52	6.36e-12	GO:0071103	DNA conformation change
2.99	4.25e-06	GO:0006325	chromatin organization
3.27	6.76e-06	GO:0034622	cellular macromolecular complex assembly
2.46	1.02e-05	GO:0006955	immune response
2.78	4.57e-05	GO:0034621	cellular macromolecular complex subunit organization
1.31	5.87e-04	GO:0050896	response to stimulus
1.92	6.47e-04	GO:0002376	immune system process
2.37	1.08e-03	GO:0051276	chromosome organization
2.09	4.00e-03	GO:0006952	defense response
2.92	7.66e-03	GO:0050778	positive regulation of immune response
2.15	8.00e-03	GO:0065003	macromolecular complex assembly
3.21	8.67e-03	GO:0002253	activation of immune response
4.28	2.67e-02	GO:0002429	immune response-activating cell surface receptor signaling pathway
1.94	3.72e-02	GO:0043933	macromolecular complex subunit organization
4.12	3.96e-02	GO:0002768	immune response-regulating cell surface receptor signaling pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
13.94	1.21e-19	GO:0000786	nucleosome
8.91	1.79e-14	GO:0032993	protein-DNA complex
5.10	1.51e-12	GO:0000785	chromatin
2.85	3.80e-06	GO:0044427	chromosomal part
2.46	9.36e-05	GO:0005694	chromosome
1.33	4.88e-03	GO:0071944	cell periphery
1.32	1.34e-02	GO:0005886	plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
11.70	7.61e-09	GO:0003823	antigen binding
1.64	3.53e-03	GO:0004872	receptor activity
1.52	1.08e-02	GO:0004871	signal transducer activity
1.52	1.08e-02	GO:0060089	molecular transducer activity