Motif ID: TCF4_dimer.p2

Z-value: 2.664


Transcription factors associated with TCF4_dimer.p2:

Gene SymbolEntrez IDGene Name
TCF4 6925 transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF4chr18_-_514063590.495.2e-02Click!


Activity profile for motif TCF4_dimer.p2.

activity profile for motif TCF4_dimer.p2


Sorted Z-values histogram for motif TCF4_dimer.p2

Sorted Z-values for motif TCF4_dimer.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF4_dimer.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_43446937 4.416 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_43447078 4.328 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_18655487 4.220 CRTC1
CREB regulated transcription coactivator 1
chr19_+_43447262 3.937 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr9_-_130980359 3.540 NM_203434
IER5L
immediate early response 5-like
chr1_+_149750485 3.155 NM_020770
CGN
cingulin
chr2_+_85834111 3.116 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr1_+_201364050 3.052 ADORA1
adenosine A1 receptor
chr8_-_49996353 3.008 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr1_-_27211913 2.987 NM_052943
FAM46B
family with sequence similarity 46, member B
chr3_-_87122936 2.819 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr14_+_101097440 2.755 NM_001362
DIO3
deiodinase, iodothyronine, type III
chr19_+_18655483 2.744 CRTC1
CREB regulated transcription coactivator 1
chr2_-_241408296 2.676 NM_004321
KIF1A
kinesin family member 1A
chr5_+_140844810 2.596 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr11_+_60391590 2.587 NM_207341
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr1_-_231498081 2.498 NM_014801
PCNXL2
pecanex-like 2 (Drosophila)
chr9_-_130980302 2.483 IER5L
immediate early response 5-like
chr4_+_54660954 2.473 NM_133267
GSX2
GS homeobox 2
chr22_+_20068039 2.439 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr17_+_45488356 2.382 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr11_-_47427263 2.367 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr22_+_38720881 2.352 NM_138435
FAM83F
family with sequence similarity 83, member F
chr6_+_42991704 2.350 NM_138296
PTCRA
pre T-cell antigen receptor alpha
chr13_+_30378311 2.318 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr10_+_99248605 2.292 NM_024954
UBTD1
ubiquitin domain containing 1
chr17_-_36577949 2.279 NM_033187
KRTAP4-3
keratin associated protein 4-3
chr17_+_45488330 2.259 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr8_-_75396016 2.242 NM_020647
JPH1
junctophilin 1
chr17_-_36594652 2.198 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr22_-_37858871 2.174 CBX7
chromobox homolog 7
chr10_-_105208634 2.146 NM_001001412
CALHM1
calcium homeostasis modulator 1
chr1_-_27212035 2.112 FAM46B
family with sequence similarity 46, member B
chr2_+_128009782 2.070 NM_001080527
MYO7B
myosin VIIB
chr15_-_38332401 2.065 NM_001039905
C15orf56
chromosome 15 open reading frame 56
chr4_-_177427252 2.003 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr15_-_46725087 1.993 NM_000138
FBN1
fibrillin 1
chr17_-_36528113 1.977 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr11_-_129803712 1.965 NM_007037
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr19_-_2259155 1.941 NM_001101391
LINGO3
leucine rich repeat and Ig domain containing 3
chr17_+_36493927 1.938 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr11_-_129803515 1.900 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr11_-_6298284 1.856 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr1_-_40140126 1.815 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr2_-_219633481 1.812 NM_002181
IHH
Indian hedgehog
chr2_+_219991342 1.798 NM_001927
DES
desmin
chr16_+_971808 1.790 NM_014587
SOX8
SRY (sex determining region Y)-box 8
chr16_+_972064 1.786 SOX8
SRY (sex determining region Y)-box 8
chrX_+_12066505 1.782 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr3_-_87122958 1.782 VGLL3
vestigial like 3 (Drosophila)
chr7_+_115953582 1.776 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr10_-_116517945 1.764 ABLIM1
actin binding LIM protein 1
chr2_+_238712101 1.761 NM_198582
KLHL30
kelch-like 30 (Drosophila)
chr13_-_78075683 1.750 NM_006237
POU4F1
POU class 4 homeobox 1
chr4_-_149582948 1.747 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr2_+_223625105 1.728 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr6_-_75972286 1.728 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr10_+_70881221 1.716 NM_012339
TSPAN15
tetraspanin 15
chr7_-_72822471 1.703 NM_001306
CLDN3
claudin 3
chr2_-_166358951 1.696 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr17_+_40655060 1.686 NM_005892
FMNL1
formin-like 1
chr4_+_185063421 1.676 NM_020225
STOX2
storkhead box 2
chr17_+_3486510 1.664 NM_001031681
NM_004937
CTNS

cystinosis, nephropathic

chr2_+_220007943 1.664 NM_005876
SPEG
SPEG complex locus
chr12_+_76749199 1.664 NM_014903
NAV3
neuron navigator 3
chr2_+_219453487 1.659 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr15_+_72005839 1.641 NM_005576
LOXL1
lysyl oxidase-like 1
chr17_+_35372751 1.638 NM_178171
GSDMA
gasdermin A
chr12_-_123023312 1.633 CCDC92
coiled-coil domain containing 92
chr6_-_75972473 1.631 COL12A1
collagen, type XII, alpha 1
chr17_-_8241868 1.628 NM_001146684
RNF222
ring finger protein 222
chr1_+_112852892 1.622 NM_024494
WNT2B
wingless-type MMTV integration site family, member 2B
chr4_-_7487514 1.621 NM_001085382
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr16_+_87232501 1.614 NM_013278
IL17C
interleukin 17C
chr2_+_219532590 1.612 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr15_+_72005847 1.604 LOXL1
lysyl oxidase-like 1
chr15_+_72006015 1.595 LOXL1
lysyl oxidase-like 1
chr5_-_168660293 1.587 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr17_-_7106987 1.577 NM_001185023
NM_001307
CLDN7

claudin 7

chr20_-_33489383 1.575 NM_000557
GDF5
growth differentiation factor 5
chr7_-_27162688 1.575 NM_006896
HOXA7
homeobox A7
chr9_+_37640996 1.573 NM_014907
FRMPD1
FERM and PDZ domain containing 1
chr3_+_141879555 1.548 NM_152616
TRIM42
tripartite motif containing 42
chr2_-_217267742 1.539 IGFBP5
insulin-like growth factor binding protein 5
chr7_+_72486044 1.532 NM_003508
FZD9
frizzled homolog 9 (Drosophila)
chr17_+_65677255 1.524 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_+_151218862 1.522 NM_001040260
NM_001040261
DCLK2

doublecortin-like kinase 2

chr13_+_111769913 1.521 NM_005986
SOX1
SRY (sex determining region Y)-box 1
chr19_-_12747263 1.504 HOOK2
hook homolog 2 (Drosophila)
chr4_+_155884564 1.501 LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr12_-_46438447 1.486 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr8_-_143692814 1.482 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr12_-_46585032 1.455 NM_000376
NM_001017535
VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

chr4_-_78038025 1.444 NM_001029870
ANKRD56
ankyrin repeat domain 56
chr16_-_76026431 1.437 NM_199355
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr11_+_63864263 1.434 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr15_-_29181198 1.431 NM_002420
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr9_-_35679902 1.411 NM_003289
NM_213674
TPM2

tropomyosin 2 (beta)

chr1_-_153107084 1.409


chr13_+_34414390 1.402 NM_015678
NBEA
neurobeachin
chr12_-_89873081 1.385 NM_152638
C12orf12
chromosome 12 open reading frame 12
chr9_+_34980266 1.381 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr17_-_36456949 1.374 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr17_-_70480345 1.360


chr2_-_175337386 1.351 NM_000079
NM_001039523
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr21_+_46355797 1.349 COL6A2
collagen, type VI, alpha 2
chr12_-_47679176 1.343 NM_015086
DDN
dendrin
chr2_-_37752731 1.338 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr3_-_123223658 1.338 NM_175924
ILDR1
immunoglobulin-like domain containing receptor 1
chr2_+_205118961 1.334 PARD3B
par-3 partitioning defective 3 homolog B (C. elegans)
chr10_+_115988999 1.327 NM_198496
VWA2
von Willebrand factor A domain containing 2
chr1_-_42157077 1.320 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr9_-_135379888 1.312 NM_001080483
TMEM8C
transmembrane protein 8C
chr3_-_39209075 1.307 NM_194293
NM_001198621
XIRP1

xin actin-binding repeat containing 1

chr15_-_23659329 1.299 NM_024490
ATP10A
ATPase, class V, type 10A
chr8_+_1909437 1.298 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr14_+_104402626 1.292 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr11_+_70915960 1.291 NM_001012503
KRTAP5-7
keratin associated protein 5-7
chr11_+_6237541 1.283 NM_176875
CCKBR
cholecystokinin B receptor
chr15_-_73818013 1.282


chr8_-_29262240 1.279 NM_057158
DUSP4
dual specificity phosphatase 4
chr11_-_118055564 1.275 NM_007180
TREH
trehalase (brush-border membrane glycoprotein)
chrX_-_128616594 1.273 NM_017413
APLN
apelin
chr14_+_104852225 1.272 PACS2
phosphofurin acidic cluster sorting protein 2
chr1_-_42156957 1.267 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr20_-_29896981 1.264 NM_004118
FOXS1
forkhead box S1
chr11_-_67163600 1.258 NM_005995
TBX10
T-box 10
chr3_+_128874458 1.257 NM_172027
ABTB1
ankyrin repeat and BTB (POZ) domain containing 1
chr16_+_1143738 1.256 CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr16_+_67236699 1.254 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr9_-_109291130 1.246 KLF4
Kruppel-like factor 4 (gut)
chr10_-_90957028 1.243 NM_003956
CH25H
cholesterol 25-hydroxylase
chr8_-_139995417 1.242 NM_152888
COL22A1
collagen, type XXII, alpha 1
chr1_+_177978920 1.242 NM_173509
FAM163A
family with sequence similarity 163, member A
chr3_-_64186151 1.233 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr17_+_1905104 1.231 NM_006497
HIC1
hypermethylated in cancer 1
chr10_+_99463446 1.224 NM_031484
MARVELD1
MARVEL domain containing 1
chr1_-_2451543 1.223 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr19_-_61874934 1.218 ZNF835
zinc finger protein 835
chr16_+_56230707 1.212 NM_001145774
GPR56
G protein-coupled receptor 56
chr5_-_176832476 1.211 NM_080881
DBN1
drebrin 1
chr6_-_39398293 1.199 NM_001135105
NM_001135106
NM_001135107
NM_032115
KCNK16



potassium channel, subfamily K, member 16



chr16_+_67236730 1.197 CDH3
cadherin 3, type 1, P-cadherin (placental)
chrX_+_71047344 1.194 NM_001013627
NHSL2
NHS-like 2
chr17_+_58058774 1.190 MRC2
mannose receptor, C type 2
chr1_-_3517918 1.190 NM_001409
MEGF6
multiple EGF-like-domains 6
chr5_-_146238336 1.188 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr16_+_29697090 1.184 ZG16
zymogen granule protein 16 homolog (rat)
chr10_+_103338030 1.174 NM_015448
DPCD
deleted in primary ciliary dyskinesia homolog (mouse)
chr2_+_120820140 1.163 NM_002193
INHBB
inhibin, beta B
chr9_-_139060285 1.162 NPDC1
neural proliferation, differentiation and control, 1
chr1_-_39877883 1.156 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr3_+_85090721 1.155 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr22_-_36212160 1.149 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr19_+_18655391 1.146 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr3_+_42702014 1.145 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chr10_+_99463468 1.144 MARVELD1
MARVEL domain containing 1
chr2_-_189752575 1.141 NM_000393
COL5A2
collagen, type V, alpha 2
chr19_+_10597167 1.133 NM_020428
SLC44A2
solute carrier family 44, member 2
chr10_-_99521701 1.132 NM_003015
SFRP5
secreted frizzled-related protein 5
chr8_-_144862266 1.131 NM_001162914
LOC100130274
coiled-coil domain containing 121-like
chr11_-_65070625 1.131 LTBP3
latent transforming growth factor beta binding protein 3
chr21_-_38210531 1.125 NM_002240
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr16_-_63713466 1.124 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr19_+_45664889 1.124 NM_020971
SPTBN4
spectrin, beta, non-erythrocytic 4
chr22_+_39096595 1.118 SGSM3
small G protein signaling modulator 3
chr17_+_71586857 1.114 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr17_+_24944605 1.104 NM_152345
ANKRD13B
ankyrin repeat domain 13B
chr12_-_68379331 1.102 NM_032735
BEST3
bestrophin 3
chr1_+_199975271 1.101 NAV1
neuron navigator 1
chr6_-_33822659 1.100 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr8_+_144888275 1.099 LOC100128338
hypothetical LOC100128338
chr9_+_101623957 1.098 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr1_-_158182006 1.096 NM_001135050
NM_020789
IGSF9

immunoglobulin superfamily, member 9

chr18_-_55091596 1.093 NM_013435
RAX
retina and anterior neural fold homeobox
chr12_+_6179736 1.093 NM_001769
CD9
CD9 molecule
chr9_-_35679799 1.089 TPM2
tropomyosin 2 (beta)
chr2_-_216944911 1.087 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr19_-_18493847 1.080 ELL
elongation factor RNA polymerase II
chr19_-_18493886 1.080 NM_006532
ELL
elongation factor RNA polymerase II
chr11_+_122936246 1.080 GRAMD1B
GRAM domain containing 1B
chr20_+_1194959 1.078 NM_014723
SNPH
syntaphilin
chr11_+_36354110 1.077 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr19_+_43502380 1.076 KCNK6
potassium channel, subfamily K, member 6
chr11_+_120478584 1.069 NM_005422
TECTA
tectorin alpha
chr5_+_74197473 1.067 LOC441086
hypothetical LOC441086
chr9_-_96441654 1.066 NM_000507
FBP1
fructose-1,6-bisphosphatase 1
chr10_-_98935369 1.066 SLIT1
slit homolog 1 (Drosophila)
chr5_+_94981735 1.065 NM_199243
GPR150
G protein-coupled receptor 150
chr19_-_7845325 1.062 NM_001190467
FLJ22184
hypothetical protein FLJ22184
chr1_-_109458001 1.060 NM_001122961
C1orf194
chromosome 1 open reading frame 194
chr11_-_67032125 1.058 CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr1_-_39871226 1.054 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr16_+_21603250 1.053 NM_001161683
OTOA
otoancorin
chr7_+_75947762 1.049 NM_001102596
DTX2
deltex homolog 2 (Drosophila)
chr16_-_73012740 1.046 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr2_-_192767494 1.044 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr1_-_109853808 1.044 NM_020703
AMIGO1
adhesion molecule with Ig-like domain 1
chr9_-_139042526 1.044 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr1_-_84237316 1.043 NM_024686
TTLL7
tubulin tyrosine ligase-like family, member 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.28 1.64e-20 GO:0048856 anatomical structure development
1.30 3.04e-20 GO:0048731 system development
1.26 1.63e-19 GO:0007275 multicellular organismal development
1.23 1.16e-17 GO:0032502 developmental process
1.17 4.13e-14 GO:0032501 multicellular organismal process
1.36 6.35e-14 GO:0007399 nervous system development
1.27 9.68e-11 GO:0030154 cell differentiation
1.28 1.19e-10 GO:0048513 organ development
1.41 2.13e-10 GO:0048468 cell development
1.26 6.16e-10 GO:0048869 cellular developmental process
1.18 1.87e-09 GO:0023052 signaling
1.30 2.22e-09 GO:0009653 anatomical structure morphogenesis
1.44 1.44e-08 GO:0030182 neuron differentiation
1.37 4.49e-08 GO:0022008 neurogenesis
1.39 4.69e-08 GO:0048699 generation of neurons
1.40 1.15e-07 GO:0007155 cell adhesion
1.40 1.15e-07 GO:0022610 biological adhesion
1.34 1.35e-07 GO:0007154 cell communication
1.16 3.27e-06 GO:0007165 signal transduction
1.36 7.54e-06 GO:0007267 cell-cell signaling
1.41 1.69e-05 GO:0048666 neuron development
1.54 2.32e-05 GO:0007411 axon guidance
1.26 2.94e-05 GO:0051239 regulation of multicellular organismal process
1.43 3.37e-05 GO:0000904 cell morphogenesis involved in differentiation
1.21 6.26e-05 GO:0007166 cell surface receptor linked signaling pathway
1.22 7.08e-05 GO:0023051 regulation of signaling
1.38 1.31e-04 GO:0009887 organ morphogenesis
1.45 1.33e-04 GO:0007409 axonogenesis
1.43 2.23e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.36 2.73e-04 GO:0032989 cellular component morphogenesis
1.54 3.00e-04 GO:0061061 muscle structure development
1.40 3.30e-04 GO:0007417 central nervous system development
1.30 3.80e-04 GO:0009888 tissue development
1.64 4.02e-04 GO:0007517 muscle organ development
1.42 5.02e-04 GO:0048812 neuron projection morphogenesis
1.32 6.90e-04 GO:2000026 regulation of multicellular organismal development
1.26 1.03e-03 GO:0010646 regulation of cell communication
1.38 1.80e-03 GO:0031175 neuron projection development
1.33 2.46e-03 GO:0030030 cell projection organization
1.27 3.73e-03 GO:0040011 locomotion
1.27 4.41e-03 GO:0006811 ion transport
1.21 4.51e-03 GO:0009966 regulation of signal transduction
1.33 4.55e-03 GO:0000902 cell morphogenesis
1.39 5.04e-03 GO:0007268 synaptic transmission
1.25 7.32e-03 GO:0009605 response to external stimulus
1.35 1.11e-02 GO:0019226 transmission of nerve impulse
1.35 1.11e-02 GO:0035637 multicellular organismal signaling
1.34 1.13e-02 GO:0006935 chemotaxis
1.34 1.13e-02 GO:0042330 taxis
1.57 1.41e-02 GO:0003012 muscle system process
1.77 1.47e-02 GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger
1.24 1.56e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.60 2.30e-02 GO:0006813 potassium ion transport
1.41 2.35e-02 GO:0044057 regulation of system process
1.34 2.83e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.07 3.00e-02 GO:0050794 regulation of cellular process
1.42 3.08e-02 GO:0060284 regulation of cell development
1.33 3.32e-02 GO:0048858 cell projection morphogenesis
1.53 3.54e-02 GO:0048732 gland development
1.44 3.58e-02 GO:0007423 sensory organ development
1.32 3.85e-02 GO:0032990 cell part morphogenesis
1.28 4.38e-02 GO:0045595 regulation of cell differentiation
1.24 4.54e-02 GO:0050793 regulation of developmental process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 1.33e-13 GO:0005886 plasma membrane
1.18 1.94e-13 GO:0071944 cell periphery
1.66 6.09e-12 GO:0031012 extracellular matrix
1.72 1.05e-11 GO:0005578 proteinaceous extracellular matrix
1.25 1.53e-11 GO:0044459 plasma membrane part
1.35 1.49e-09 GO:0044421 extracellular region part
1.10 6.44e-09 GO:0016020 membrane
1.23 1.33e-08 GO:0005576 extracellular region
1.11 1.36e-07 GO:0044425 membrane part
2.17 2.73e-07 GO:0045095 keratin filament
1.28 4.24e-07 GO:0031226 intrinsic to plasma membrane
1.11 8.59e-07 GO:0031224 intrinsic to membrane
1.27 1.31e-06 GO:0005887 integral to plasma membrane
1.11 7.37e-06 GO:0016021 integral to membrane
1.78 9.69e-05 GO:0043292 contractile fiber
1.81 1.00e-04 GO:0044420 extracellular matrix part
1.29 2.00e-04 GO:0005615 extracellular space
1.34 2.23e-04 GO:0030054 cell junction
1.78 2.72e-04 GO:0044449 contractile fiber part
1.76 3.25e-04 GO:0030016 myofibril
1.53 1.05e-03 GO:0034702 ion channel complex
1.77 2.10e-03 GO:0030017 sarcomere
1.58 2.29e-03 GO:0005882 intermediate filament
1.53 3.18e-03 GO:0045111 intermediate filament cytoskeleton
1.35 6.23e-03 GO:0045202 synapse
2.02 1.30e-02 GO:0043197 dendritic spine
1.83 1.42e-02 GO:0005604 basement membrane
1.33 2.54e-02 GO:0043005 neuron projection
1.50 2.62e-02 GO:0043025 neuronal cell body
1.38 3.07e-02 GO:0044456 synapse part
1.78 3.18e-02 GO:0042383 sarcolemma
1.94 3.62e-02 GO:0044309 neuron spine
2.12 3.79e-02 GO:0005581 collagen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.99 1.04e-04 GO:0005201 extracellular matrix structural constituent
1.33 1.23e-04 GO:0043565 sequence-specific DNA binding
1.42 1.31e-04 GO:0022803 passive transmembrane transporter activity
1.42 1.89e-04 GO:0015267 channel activity
1.42 2.94e-04 GO:0005216 ion channel activity
1.42 3.06e-04 GO:0022838 substrate-specific channel activity
1.46 5.73e-04 GO:0022836 gated channel activity
1.71 1.40e-03 GO:0005267 potassium channel activity
1.25 1.77e-03 GO:0022857 transmembrane transporter activity
1.47 1.95e-03 GO:0005261 cation channel activity
1.30 3.31e-03 GO:0005198 structural molecule activity
2.18 4.94e-03 GO:0008307 structural constituent of muscle
1.34 7.71e-03 GO:0030695 GTPase regulator activity
1.33 7.72e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.26 9.78e-03 GO:0015075 ion transmembrane transporter activity
1.27 1.30e-02 GO:0005509 calcium ion binding
1.23 1.51e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.22 1.55e-02 GO:0030528 transcription regulator activity
1.21 1.66e-02 GO:0005102 receptor binding
1.19 2.52e-02 GO:0005215 transporter activity
1.61 2.97e-02 GO:0015276 ligand-gated ion channel activity
1.61 2.97e-02 GO:0022834 ligand-gated channel activity
1.37 3.21e-02 GO:0003779 actin binding