Motif ID: TEAD1.p2

Z-value: 3.294


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD1chr11_+_129173690.911.2e-06Click!
TEAD4chr12_+_29387030.853.3e-05Click!
TEAD2chr19_-_545574500.165.6e-01Click!
TEAD3chr6_-_355726940.078.0e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_132314004 9.323 NM_001901
CTGF
connective tissue growth factor
chr19_+_39664706 8.956 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr1_-_212791597 8.621 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr3_-_135575925 8.551 NM_016201
AMOTL2
angiomotin like 2
chr1_-_212791467 7.842 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr15_+_37660568 6.117 NM_003246
THBS1
thrombospondin 1
chr4_+_184257337 5.285 NM_024949
WWC2
WW and C2 domain containing 2
chr6_-_75972286 4.878 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr10_-_125843092 4.519 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr5_-_39460687 4.481 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_-_1283770 4.148 NM_032348
MXRA8
matrix-remodelling associated 8
chr15_+_73728402 3.950 NM_153271
SNX33
sorting nexin 33
chr3_-_113841967 3.812 CCDC80
coiled-coil domain containing 80
chr14_-_88090641 3.721 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr1_-_16355013 3.698 NM_004431
EPHA2
EPH receptor A2
chr14_-_22516271 3.633 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr2_-_189752575 3.585 NM_000393
COL5A2
collagen, type V, alpha 2
chr14_-_22515725 3.572 JUB
jub, ajuba homolog (Xenopus laevis)
chr11_-_6298284 3.496 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr1_+_85819004 3.461 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr6_-_128883125 3.419 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr8_+_1759502 3.379 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr10_+_102782151 3.377 SFXN3
sideroflexin 3
chr9_+_136673534 3.341 COL5A1
collagen, type V, alpha 1
chr19_-_49523747 3.339 ZFP112
zinc finger protein 112 homolog (mouse)
chr3_-_113842133 3.326 CCDC80
coiled-coil domain containing 80
chr1_-_199613427 3.305 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr3_-_113841941 3.299 CCDC80
coiled-coil domain containing 80
chr3_+_9919295 3.241 NM_153483
IL17RE
interleukin 17 receptor E
chr15_-_39973566 3.201 NM_016642
SPTBN5
spectrin, beta, non-erythrocytic 5
chr7_+_134114912 3.195 CALD1
caldesmon 1
chr17_-_37828643 3.144 NM_012232
PTRF
polymerase I and transcript release factor
chr3_-_113842350 3.115 CCDC80
coiled-coil domain containing 80
chr3_-_113842255 3.053 CCDC80
coiled-coil domain containing 80
chr19_-_14467939 2.925 NM_005716
NM_202467
NM_202468
NM_202469
NM_202470
NM_202494
GIPC1





GIPC PDZ domain containing family, member 1





chr18_+_8707368 2.920 NM_015210
KIAA0802
KIAA0802
chr11_-_8789457 2.887 NM_139157
ST5
suppression of tumorigenicity 5
chr19_-_14467890 2.873 GIPC1
GIPC PDZ domain containing family, member 1
chr5_-_39460787 2.697 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr3_-_113842553 2.671 CCDC80
coiled-coil domain containing 80
chr4_-_152368492 2.635 SH3D19
SH3 domain containing 19
chr7_+_134114701 2.567 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr3_-_113842652 2.547 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr22_+_22907443 2.487 NM_019601
SUSD2
sushi domain containing 2
chr8_-_13018123 2.464 NM_001164271
DLC1
deleted in liver cancer 1
chr11_-_8788765 2.462 NM_213618
ST5
suppression of tumorigenicity 5
chr11_-_47427263 2.460 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr5_-_39461054 2.401 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr12_+_51728999 2.380 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr6_-_75972473 2.347 COL12A1
collagen, type XII, alpha 1
chr2_+_102125616 2.343 IL1R1
interleukin 1 receptor, type I
chr22_+_40286957 2.329 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr8_+_70541412 2.287 NM_001128204
NM_015170
SULF1

sulfatase 1

chr6_-_42218692 2.275 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr3_+_9919511 2.274 NM_001193380
NM_153480
IL17RE

interleukin 17 receptor E

chr10_+_102782156 2.242 SFXN3
sideroflexin 3
chr6_+_134251957 2.229 TCF21
transcription factor 21
chr15_+_61121806 2.225 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr6_+_134251940 2.221 NM_198392
NM_003206
TCF21

transcription factor 21

chr1_+_181421796 2.198 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr21_-_26345294 2.193


chr17_-_24973940 2.185 CORO6
coronin 6
chr1_+_181422016 2.175 LAMC2
laminin, gamma 2
chr6_+_83130220 2.163 TPBG
trophoblast glycoprotein
chr1_-_207892420 2.138 NM_000228
LAMB3
laminin, beta 3
chr1_+_181421984 2.131 LAMC2
laminin, gamma 2
chr1_-_199704773 2.090 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr5_-_151046680 2.076 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr5_-_151046638 2.049 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chrX_-_106129854 2.024 MORC4
MORC family CW-type zinc finger 4
chr17_+_71229151 2.015 ITGB4
integrin, beta 4
chr13_+_109936080 1.988 COL4A2
collagen, type IV, alpha 2
chr15_-_67494412 1.987 LOC145694
hypothetical LOC145694
chr2_-_192420168 1.955 NM_004657
SDPR
serum deprivation response
chr5_-_37871349 1.945 NM_199231
GDNF
glial cell derived neurotrophic factor
chr12_-_119172339 1.938 NM_025157
PXN
paxillin
chr5_-_37871685 1.935 NM_001190468
NM_001190469
GDNF

glial cell derived neurotrophic factor

chr3_-_113842237 1.917 CCDC80
coiled-coil domain containing 80
chr2_-_192419896 1.910 SDPR
serum deprivation response
chr7_+_134114957 1.890 CALD1
caldesmon 1
chr1_-_207892296 1.890 NM_001127641
LAMB3
laminin, beta 3
chr11_-_46896484 1.878 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr19_+_58239802 1.871 NM_001191055
HERV-V2
envelope glycoprotein ENVV2
chr22_+_22907417 1.862 SUSD2
sushi domain containing 2
chr2_-_160972606 1.857 RBMS1
RNA binding motif, single stranded interacting protein 1
chr10_+_123862430 1.842 TACC2
transforming, acidic coiled-coil containing protein 2
chr7_+_115952279 1.833 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr2_-_215955206 1.830 FN1
fibronectin 1
chr12_-_47464143 1.812 NM_015270
ADCY6
adenylate cyclase 6
chr11_-_85107569 1.810 NM_206929
SYTL2
synaptotagmin-like 2
chr5_-_58918031 1.801 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_7136147 1.780 NM_001733
C1R
complement component 1, r subcomponent
chr9_+_115970599 1.778 COL27A1
collagen, type XXVII, alpha 1
chrX_-_10548458 1.764 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr19_+_50041424 1.744 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr9_+_34980715 1.717 DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr3_+_148609841 1.700 NM_003412
ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr15_+_61122139 1.675 TPM1
tropomyosin 1 (alpha)
chr17_+_71229191 1.670 ITGB4
integrin, beta 4
chr12_-_13044448 1.656 HEBP1
heme binding protein 1
chr5_+_34723420 1.644 NM_001145523
RAI14
retinoic acid induced 14
chr12_-_7136189 1.642 C1R
complement component 1, r subcomponent
chr6_-_134538762 1.638 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr12_+_27568311 1.631 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr11_-_2127368 1.628 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_95303947 1.626 PROM2
prominin 2
chr5_-_148422799 1.621 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr1_-_148175383 1.616 NM_001145862
MTMR11
myotubularin related protein 11
chr12_-_53099277 1.615 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chrX_-_53327473 1.610 NM_015075
IQSEC2
IQ motif and Sec7 domain 2
chr16_-_62573 1.594 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr1_-_153272859 1.583 NM_144622
DCST2
DC-STAMP domain containing 2
chr6_+_83129641 1.575 NM_006670
TPBG
trophoblast glycoprotein
chr2_-_217248967 1.568 IGFBP5
insulin-like growth factor binding protein 5
chr3_-_10522267 1.562 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr3_-_129023850 1.553 NM_007283
MGLL
monoglyceride lipase
chr1_+_216585298 1.552 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr10_-_17699309 1.516 PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr20_+_34603311 1.488 MYL9
myosin, light chain 9, regulatory
chr5_+_176446425 1.464 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr12_-_53099269 1.460 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr9_+_112470871 1.457 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chrX_+_106050261 1.454 NM_020384
CLDN2
claudin 2
chr14_+_54102518 1.449 LOC644925
hypothetical LOC644925
chr2_-_220116062 1.441 NM_001195731
CHPF
chondroitin polymerizing factor
chrX_-_152794592 1.427 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chr12_-_15706340 1.410 EPS8
epidermal growth factor receptor pathway substrate 8
chr3_-_115825742 1.406 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_53099203 1.385 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr14_-_22521544 1.376 NM_032876
JUB
jub, ajuba homolog (Xenopus laevis)
chr12_-_94708641 1.363 NM_021229
NTN4
netrin 4
chr3_+_125586241 1.362 KALRN
kalirin, RhoGEF kinase
chr1_+_238321794 1.335 NM_020066
FMN2
formin 2
chr3_-_150533948 1.330 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr4_-_89837951 1.328 NM_153757
NAP1L5
nucleosome assembly protein 1-like 5
chr11_+_46323495 1.316 DGKZ
diacylglycerol kinase, zeta
chr1_-_151848039 1.282 S100A16
S100 calcium binding protein A16
chr17_+_3486510 1.273 NM_001031681
NM_004937
CTNS

cystinosis, nephropathic

chr17_+_71229110 1.272 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr3_+_50281309 1.265 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr20_+_34603290 1.263 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory

chrX_-_83644054 1.258 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr7_+_115952074 1.256 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr2_+_95303922 1.243 NM_001165977
NM_001165978
NM_144707
PROM2


prominin 2


chr11_+_19328846 1.241 NM_001111018
NAV2
neuron navigator 2
chr11_+_124294355 1.241 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr6_+_131508153 1.228 NM_016377
AKAP7
A kinase (PRKA) anchor protein 7
chr18_-_19496590 1.226 NM_173505
ANKRD29
ankyrin repeat domain 29
chr12_-_13044314 1.222 HEBP1
heme binding protein 1
chr8_-_38444398 1.216 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chr19_-_41514390 1.212


chr12_-_54387934 1.212 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chr11_+_113671744 1.211 NM_006169
NNMT
nicotinamide N-methyltransferase
chr6_-_134538526 1.210 SGK1
serum/glucocorticoid regulated kinase 1
chr12_-_54387732 1.208 ITGA7
integrin, alpha 7
chr18_+_13815542 1.177 NM_005913
MC5R
melanocortin 5 receptor
chr12_-_13044467 1.175 NM_015987
HEBP1
heme binding protein 1
chr15_-_93671314 1.175 LOC400456
hypothetical LOC400456
chr1_-_201411533 1.170 NM_004997
MYBPH
myosin binding protein H
chr3_+_113061218 1.156 NM_001134439
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr11_-_124311512 1.153 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr19_+_41980248 1.151 LOC284408
hypothetical LOC284408
chr5_+_140848905 1.148 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr2_-_75641587 1.121 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr2_-_75641535 1.118 FAM176A
family with sequence similarity 176, member A
chr12_+_77782579 1.108 NM_005639
SYT1
synaptotagmin I
chr1_-_17179694 1.105 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr6_-_167491305 1.102 NM_005299
GPR31
G protein-coupled receptor 31
chr11_+_66580861 1.094 NM_014578
RHOD
ras homolog gene family, member D
chr5_+_38882017 1.089 OSMR
oncostatin M receptor
chr5_+_76150637 1.086 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr5_+_150138489 1.082 C5orf62
chromosome 5 open reading frame 62
chr6_+_158322875 1.080 NM_003898
SYNJ2
synaptojanin 2
chr19_-_54063522 1.075 NM_001161354
NM_020904
PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr9_+_88953378 1.069 NM_001001709
C9orf170
chromosome 9 open reading frame 170
chr11_+_66580884 1.061 RHOD
ras homolog gene family, member D
chr14_-_22974707 1.058 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr12_+_77782648 1.048 SYT1
synaptotagmin I
chr1_-_148175345 1.045 MTMR11
myotubularin related protein 11
chr9_+_111927601 1.036 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr5_-_38631263 1.022 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr19_-_13909877 1.014 PODNL1
podocan-like 1
chr1_-_24311212 1.013 NM_152372
MYOM3
myomesin family, member 3
chr11_+_57123927 1.011 SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr8_-_146173531 1.011 ZNF252
zinc finger protein 252
chr8_-_38444675 1.011 FGFR1
fibroblast growth factor receptor 1
chr12_+_2938703 1.007 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr6_-_3102690 1.005 NM_001069
TUBB2A
tubulin, beta 2A
chr3_-_48446405 1.003 NM_001130082
PLXNB1
plexin B1
chr9_+_90339835 0.996 NM_001161625
NM_145283
NXNL2

nucleoredoxin-like 2

chr9_-_106705780 0.987 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr1_-_158098962 0.980 NM_001013661
VSIG8
V-set and immunoglobulin domain containing 8
chr11_-_10630408 0.980 NM_001098579
MRVI1
murine retrovirus integration site 1 homolog
chr9_-_16717887 0.979 BNC2
basonuclin 2
chr4_-_171247757 0.978 NM_016228
AADAT
aminoadipate aminotransferase
chr4_-_184480572 0.977 NM_001185149
CLDN24
claudin 24
chr11_-_126375895 0.969 NM_001161707
NM_032531
KIRREL3

kin of IRRE like 3 (Drosophila)

chr16_+_2461500 0.965 NM_006181
NTN3
netrin 3
chr7_+_115952325 0.963 CAV1
caveolin 1, caveolae protein, 22kDa
chr1_+_114323552 0.956 NM_020190
OLFML3
olfactomedin-like 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.97 6.53e-05 GO:0007155 cell adhesion
1.97 6.53e-05 GO:0022610 biological adhesion
1.77 1.63e-03 GO:0048468 cell development
1.34 2.79e-03 GO:0007275 multicellular organismal development
1.31 4.05e-03 GO:0032502 developmental process
1.38 4.84e-03 GO:0048731 system development
1.55 5.61e-03 GO:0009653 anatomical structure morphogenesis
1.35 5.65e-03 GO:0048856 anatomical structure development
2.03 8.62e-03 GO:0072358 cardiovascular system development
2.03 8.62e-03 GO:0072359 circulatory system development
2.35 1.05e-02 GO:0001944 vasculature development
1.24 1.20e-02 GO:0032501 multicellular organismal process
2.37 1.61e-02 GO:0001568 blood vessel development
1.45 1.83e-02 GO:0048513 organ development
2.52 2.01e-02 GO:0048514 blood vessel morphogenesis
3.07 2.65e-02 GO:0014706 striated muscle tissue development
2.25 3.46e-02 GO:0030029 actin filament-based process
2.28 3.57e-02 GO:0061061 muscle structure development
2.21 3.85e-02 GO:0022603 regulation of anatomical structure morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.54 5.52e-06 GO:0005576 extracellular region
3.71 2.78e-05 GO:0044420 extracellular matrix part
2.32 5.66e-05 GO:0031012 extracellular matrix
1.31 1.02e-04 GO:0071944 cell periphery
1.46 1.27e-04 GO:0044459 plasma membrane part
1.30 3.04e-04 GO:0005886 plasma membrane
2.40 3.46e-04 GO:0015629 actin cytoskeleton
1.68 4.64e-04 GO:0044421 extracellular region part
2.31 6.04e-04 GO:0005578 proteinaceous extracellular matrix
4.08 8.98e-04 GO:0005604 basement membrane
2.45 2.17e-02 GO:0031252 cell leading edge
5.44 2.25e-02 GO:0001725 stress fiber
12.70 3.45e-02 GO:0001527 microfibril
5.08 3.86e-02 GO:0032432 actin filament bundle

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.41 1.17e-04 GO:0003779 actin binding
3.38 1.39e-03 GO:0019838 growth factor binding
3.81 1.70e-03 GO:0005201 extracellular matrix structural constituent
2.83 4.87e-03 GO:0005539 glycosaminoglycan binding
2.74 5.42e-03 GO:0001871 pattern binding
2.74 5.42e-03 GO:0030247 polysaccharide binding
1.88 5.68e-03 GO:0008092 cytoskeletal protein binding
1.76 9.92e-03 GO:0005509 calcium ion binding
6.10 1.39e-02 GO:0050840 extracellular matrix binding
4.43 3.05e-02 GO:0008307 structural constituent of muscle
7.62 3.50e-02 GO:0043236 laminin binding
2.89 3.74e-02 GO:0008201 heparin binding