Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 0.967


Transcription factors associated with ADNP_IRX_SIX_ZHX.p2:

Gene SymbolEntrez IDGene Name
ADNP 23394 activity-dependent neuroprotector homeobox
IRX4 50805 iroquois homeobox 4
IRX5 10265 iroquois homeobox 5
SIX2 10736 SIX homeobox 2
SIX5 147912 SIX homeobox 5
ZHX1 11244 zinc fingers and homeoboxes 1
ZHX2 22882 zinc fingers and homeoboxes 2
ZHX3 23051 zinc fingers and homeoboxes 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZHX2chr8_+_123863075-0.683.4e-03Click!
ZHX1chr8_-_1243556700.621.0e-02Click!
ADNPchr20_-_489808580.449.1e-02Click!
IRX5chr16_+_535226110.431.0e-01Click!
ZHX3chr20_-_39379533-0.381.4e-01Click!
SIX5chr19_-_50964336-0.332.1e-01Click!
IRX4chr5_-_19357640.185.0e-01Click!
SIX2chr2_-_45090025-0.175.3e-01Click!


Activity profile for motif ADNP_IRX_SIX_ZHX.p2.

activity profile for motif ADNP_IRX_SIX_ZHX.p2


Sorted Z-values histogram for motif ADNP_IRX_SIX_ZHX.p2

Sorted Z-values for motif ADNP_IRX_SIX_ZHX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ADNP_IRX_SIX_ZHX.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_57209319 1.974 NM_003865
HESX1
HESX homeobox 1
chr6_-_49820030 1.517 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr8_-_86477585 1.459 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr22_-_34566367 1.396 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chrX_-_153698930 1.386 HMGN1P37
high-mobility group nucleosome binding domain 1 pseudogene 37
chr3_-_143230124 1.344 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr7_-_13992351 1.321 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr1_+_166516901 1.311 NM_005149
TBX19
T-box 19
chr4_-_91979113 1.294 NM_183049
TMSL3
thymosin-like 3
chr9_-_14076901 1.287 NFIB
nuclear factor I/B
chr1_+_556968 1.262


chr9_-_99740243 1.172 NM_197978
HEMGN
hemogen
chr1_-_93030538 1.157 NM_005665
EVI5
ecotropic viral integration site 5
chr11_-_33870411 1.112 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_+_52696908 1.066 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr1_-_156923111 1.049 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr10_+_5126556 1.003 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_5126589 0.981 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_5126613 0.950 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr12_+_52697160 0.937 HOXC5
HOXC6
homeobox C5
homeobox C6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.61 1.50e-14 GO:0007608 sensory perception of smell
2.57 1.15e-15 GO:0007606 sensory perception of chemical stimulus
2.06 1.76e-13 GO:0007600 sensory perception
1.66 5.43e-09 GO:0050877 neurological system process
1.57 1.21e-08 GO:0003008 system process
1.25 1.79e-06 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.21 8.10e-04 GO:0071944 cell periphery
1.21 1.32e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.68 1.57e-15 GO:0004984 olfactory receptor activity
1.97 2.21e-12 GO:0004930 G-protein coupled receptor activity
1.69 5.09e-10 GO:0004888 transmembrane receptor activity
1.51 9.00e-08 GO:0004872 receptor activity
1.38 3.10e-05 GO:0004871 signal transducer activity
1.38 3.10e-05 GO:0060089 molecular transducer activity