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Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 0.967

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_-_57209319	1.974	NM_003865	HESX1	HESX homeobox 1
chr6_-_49820030	1.517	NM_001190986 NM_006061	CRISP3	cysteine-rich secretory protein 3
chr8_-_86477585	1.459	NM_001128829 NM_001128830 NM_001128831 NM_001738	CA1	carbonic anhydrase I
chr22_-_34566367	1.396	NM_001031695 NM_001082576 NM_001082577 NM_014309	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_153698930	1.386		HMGN1P37	high-mobility group nucleosome binding domain 1 pseudogene 37
chr3_-_143230124	1.344	NM_001178141 NM_001178142 NM_006286	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr7_-_13992351	1.321	NM_001163150 NM_001163151 NM_001163152	ETV1	ets variant 1
chr1_+_166516901	1.311	NM_005149	TBX19	T-box 19
chr4_-_91979113	1.294	NM_183049	TMSL3	thymosin-like 3
chr9_-_14076901	1.287		NFIB	nuclear factor I/B
chr1_+_556968	1.262
chr9_-_99740243	1.172	NM_197978	HEMGN	hemogen
chr1_-_93030538	1.157	NM_005665	EVI5	ecotropic viral integration site 5
chr11_-_33870411	1.112	NM_005574	LMO2	LIM domain only 2 (rhombotin-like 1)
chr12_+_52696908	1.066	NM_014620 NM_153693	HOXC4 HOXC6	homeobox C4 homeobox C6
chr1_-_156923111	1.049	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr10_+_5126556	1.003	NM_003739	AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_5126589	0.981		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_5126613	0.950		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr12_+_52697160	0.937		HOXC5 HOXC6	homeobox C5 homeobox C6
chr2_+_157822355	0.921	NM_014568	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr7_-_107667728	0.917	NM_001037132	NRCAM	neuronal cell adhesion molecule
chr1_+_86707113	0.913	NM_001285	CLCA1	chloride channel accessory 1
chr7_-_92693716	0.907	NM_001039372	HEPACAM2	HEPACAM family member 2
chr4_-_79322295	0.902
chr17_-_44037332	0.899	NM_018952	HOXB6	homeobox B6
chr1_-_180822686	0.872	NM_021133	RNASEL	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr9_-_205892	0.856	NM_152569	C9orf66	chromosome 9 open reading frame 66
chr7_-_16471817	0.847	NM_015464	SOSTDC1	sclerostin domain containing 1
chrX_-_137649180	0.838	NM_033642	FGF13	fibroblast growth factor 13
chr7_+_106897737	0.819	NM_005295	GPR22	G protein-coupled receptor 22
chr11_+_123600553	0.812	NM_001007249	OR8G2	olfactory receptor, family 8, subfamily G, member 2
chr6_-_10523424	0.805	NM_003220	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr4_+_3285671	0.771	NM_002926 NM_198229	RGS12	regulator of G-protein signaling 12
chr15_+_91244563	0.758		CHD2	chromodomain helicase DNA binding protein 2
chr12_-_69434330	0.753		PTPRR	protein tyrosine phosphatase, receptor type, R
chr22_-_34566276	0.749		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr22_-_34566210	0.733		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_+_69895651	0.722	NM_006722	MITF	microphthalmia-associated transcription factor
chr12_+_103677388	0.719		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr7_+_129771865	0.716	NM_001127441 NM_001127442 NM_080385	CPA5	carboxypeptidase A5
chr8_-_72431274	0.713	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr7_-_142369519	0.706		KEL	Kell blood group, metallo-endopeptidase
chr1_+_61642287	0.694		NFIA	nuclear factor I/A
chr6_+_112775224	0.690	NM_001013734	RFPL4B	ret finger protein-like 4B
chr17_-_30909219	0.686	NM_001129820	SLFN14	schlafen family member 14
chr10_+_70745615	0.685	NM_033496	HK1	hexokinase 1
chr2_+_220087135	0.678	NM_018674 NM_182847	ACCN4	amiloride-sensitive cation channel 4, pituitary
chr7_-_135263737	0.678		MTPN LUZP6	myotrophin leucine zipper protein 6
chr21_-_14840506	0.671	NM_022136	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chrX_-_119593646	0.670	NM_003588	CUL4B	cullin 4B
chr4_-_74307637	0.660		ANKRD17	ankyrin repeat domain 17
chr6_+_105511615	0.659	NM_001004317	LIN28B	lin-28 homolog B (C. elegans)
chr5_+_140751666	0.653	NM_014004 NM_032088	PCDHGA8	protocadherin gamma subfamily A, 8
chr11_-_128399218	0.650	NM_014715	ARHGAP32	Rho GTPase activating protein 32
chr5_-_1935764	0.643	NM_016358	IRX4	iroquois homeobox 4
chrX_-_102828238	0.641	NM_001142418 NM_001142423 NM_001142424 NM_001142425 NM_001142426 NM_001142429 NM_001142430 NM_012286	MORF4L2	mortality factor 4 like 2
chr16_+_7322751	0.633	NM_145891 NM_145892 NM_145893	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_+_178893216	0.625	NM_145739	OSBPL6	oxysterol binding protein-like 6
chr12_-_51200347	0.623	NM_000424	KRT5	keratin 5
chr15_-_74091817	0.619	NM_138573	NRG4	neuregulin 4
chr16_+_33112480	0.615	NM_016212	TP53TG3	TP53 target 3
chr11_+_113671744	0.606	NM_006169	NNMT	nicotinamide N-methyltransferase
chr4_-_54152480	0.597	NM_001126328	LNX1	ligand of numb-protein X 1
chrX_-_15593074	0.596	NM_020665	TMEM27	transmembrane protein 27
chr11_+_113672407	0.594		NNMT	nicotinamide N-methyltransferase
chr14_-_80934523	0.591	NM_033104	STON2	stonin 2
chr16_+_33169015	0.590	NM_016212	TP53TG3	TP53 target 3
chr1_-_42738535	0.588		TMSB4XP1	thymosin beta 4, X-linked pseudogene 1
chr12_+_52680143	0.586	NM_006897	HOXC9	homeobox C9
chr7_-_112514990	0.585		GPR85	G protein-coupled receptor 85
chr17_-_36877002	0.584	NM_002278	KRT32	keratin 32
chr11_+_113672378	0.583		NNMT	nicotinamide N-methyltransferase
chr8_-_10550026	0.577	NM_178857	RP1L1	retinitis pigmentosa 1-like 1
chr1_+_165564904	0.576	NM_001198783	POU2F1	POU class 2 homeobox 1
chr21_+_38550739	0.568	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr12_+_56802	0.567	NM_015232	IQSEC3	IQ motif and Sec7 domain 3
chr1_+_165565006	0.566		POU2F1	POU class 2 homeobox 1
chr18_+_31488530	0.564	NM_020474	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr18_+_27210737	0.563	NM_001134453 NM_177986	DSG4	desmoglein 4
chr15_+_91244422	0.556	NM_001042572 NM_001271	CHD2	chromodomain helicase DNA binding protein 2
chr7_-_13996166	0.555	NM_001163147 NM_004956	ETV1	ets variant 1
chr7_-_100262971	0.549	NM_004444	EPHB4	EPH receptor B4
chr1_-_157950898	0.546	NM_000567	CRP	C-reactive protein, pentraxin-related
chr3_-_197726587	0.545	NM_001077657	C3orf43	chromosome 3 open reading frame 43
chr14_-_68424653	0.543		ACTN1	actinin, alpha 1
chr1_+_203503214	0.542		TMCC2	transmembrane and coiled-coil domain family 2
chr7_-_112515068	0.534	NM_001146265 NM_018970	GPR85	G protein-coupled receptor 85
chr16_+_2593351	0.530		LOC652276	hypothetical LOC652276
chr3_-_147696411	0.524	NM_020359	PLSCR2	phospholipid scramblase 2
chr11_-_123353607	0.521	NM_001004474	OR10S1	olfactory receptor, family 10, subfamily S, member 1
chr12_+_28301399	0.519	NM_018318	CCDC91	coiled-coil domain containing 91
chr1_+_22107137	0.517		RPL21	ribosomal protein L21
chr9_-_122679283	0.516		PHF19	PHD finger protein 19
chr10_+_83627422	0.514	NM_001165973	NRG3	neuregulin 3
chr4_+_22608252	0.510
chr12_-_69434650	0.509		PTPRR	protein tyrosine phosphatase, receptor type, R
chr1_+_557269	0.507
chr4_-_54152385	0.503		LNX1	ligand of numb-protein X 1
chr3_+_11242666	0.499	NM_001098211	HRH1	histamine receptor H1
chr9_+_129900637	0.491	NM_052901 NM_001006643	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr2_+_28892366	0.491	NM_001008779	SPDYA	speedy homolog A (Xenopus laevis)
chr15_-_64108718	0.490
chr9_+_95886625	0.487		PTPDC1	protein tyrosine phosphatase domain containing 1
chr2_+_225973845	0.486	NM_020864	KIAA1486	KIAA1486
chr5_-_75044001	0.483	NM_152408	POC5	POC5 centriolar protein homolog (Chlamydomonas)
chr11_+_93940121	0.481	NM_152431	PIWIL4	piwi-like 4 (Drosophila)
chr6_+_155579788	0.477	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr10_+_4995453	0.474	NM_001353	AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr10_+_70517823	0.469	NM_002727	SRGN	serglycin
chr13_+_107753764	0.466
chr1_+_84646621	0.463	NM_058248	DNASE2B	deoxyribonuclease II beta
chr1_-_205272619	0.455	NM_001083924 NM_023938	C1orf116	chromosome 1 open reading frame 116
chr17_-_16038607	0.454	NM_001190438 NM_001190440	NCOR1	nuclear receptor corepressor 1
chr10_+_70517863	0.453		SRGN	serglycin
chr5_+_140698537	0.451	NM_018915 NM_032009	PCDHGA2	protocadherin gamma subfamily A, 2
chr9_+_129900590	0.450		SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr12_+_43972732	0.448	NM_001142678	ANO6	anoctamin 6
chr9_+_134843918	0.446	NM_001135031 NM_004188	GFI1B	growth factor independent 1B transcription repressor
chr4_-_69218909	0.445	NM_001076	UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15
chr10_+_63331401	0.445		ARID5B	AT rich interactive domain 5B (MRF1-like)
chr3_+_35697432	0.444	NM_198399	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr7_-_112515035	0.443		GPR85	G protein-coupled receptor 85
chr11_+_120478584	0.443	NM_005422	TECTA	tectorin alpha
chr9_+_95886558	0.442	NM_152422	PTPDC1	protein tyrosine phosphatase domain containing 1
chr7_+_113853790	0.441	NM_001172767 NM_148899	FOXP2	forkhead box P2
chr16_+_33168191	0.441	NM_001099687	TP53TG3B	TP53 target 3B
chr21_+_37713076	0.439	NM_130436	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr9_-_27287106	0.439	NM_001161585 NM_020641	C9orf11	chromosome 9 open reading frame 11
chr4_-_68793928	0.439	NM_182502	TMPRSS11B	transmembrane protease, serine 11B
chr1_+_152560179	0.438	NM_080429	AQP10	aquaporin 10
chr9_-_122679387	0.432	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr5_-_134291882	0.429
chr15_+_38319326	0.426	NM_020168	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr15_+_71522551	0.425	NM_001042367	C15orf60	chromosome 15 open reading frame 60
chr17_-_74361620	0.422		TIMP2	TIMP metallopeptidase inhibitor 2
chr5_+_140605100	0.422		PCDHB15	protocadherin beta 15
chr13_+_52114565	0.421		HNRNPA1L2	heterogeneous nuclear ribonucleoprotein A1-like 2
chr11_-_16454493	0.419	NM_033326	SOX6	SRY (sex determining region Y)-box 6
chr17_-_10393664	0.418	NM_001100112 NM_017534	MYH2	myosin, heavy chain 2, skeletal muscle, adult
chrX_-_55074125	0.417	NM_000032 NM_001037967 NM_001037968	ALAS2	aminolevulinate, delta-, synthase 2
chr5_-_134290789	0.416
chr2_-_160838397	0.414		RBMS1	RNA binding motif, single stranded interacting protein 1
chr4_+_74825138	0.414	NM_000584	IL8	interleukin 8
chr4_+_140806536	0.414		MGST2	microsomal glutathione S-transferase 2
chr6_-_28429950	0.411	NM_145909	ZNF323	zinc finger protein 323
chr18_-_59480082	0.410	NM_006919	SERPINB3 SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 3 serpin peptidase inhibitor, clade B (ovalbumin), member 4
chrX_+_99726445	0.410	NM_022144	TNMD	tenomodulin
chr2_-_200030412	0.406		SATB2	SATB homeobox 2
chr10_-_5035967	0.406	NM_001135241	AKR1C1 AKR1C2	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr12_-_69434598	0.405	NM_130846	PTPRR	protein tyrosine phosphatase, receptor type, R
chr7_-_13995811	0.400		ETV1	ets variant 1
chr19_+_61039755	0.396	NM_134444	NLRP4	NLR family, pyrin domain containing 4
chr7_+_129634935	0.394	NM_145268	C7orf45	chromosome 7 open reading frame 45
chr7_-_75794919	0.389		YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr1_+_51855133	0.388	NM_024586 NM_148906 NM_148908 NM_148909	OSBPL9	oxysterol binding protein-like 9
chrX_+_44588192	0.387	NM_022076	DUSP21	dual specificity phosphatase 21
chr5_+_38481392	0.385	NM_182801	EGFLAM	EGF-like, fibronectin type III and laminin G domains
chr12_-_51476047	0.384	NM_057088	KRT3	keratin 3
chr6_-_2696152	0.384	NM_001012418	MYLK4	myosin light chain kinase family, member 4
chr1_-_120189301	0.384	NM_001047980	NBPF7	neuroblastoma breakpoint family, member 7
chr2_-_87906400	0.384	NM_001078170	RGPD2	RANBP2-like and GRIP domain containing 2
chr4_+_109033868	0.383	NM_001136257 NM_152621	SGMS2	sphingomyelin synthase 2
chr5_+_42792676	0.381	NM_001134848	CCDC152	coiled-coil domain containing 152
chr2_+_108571177	0.378	NM_004987	LIMS1	LIM and senescent cell antigen-like domains 1
chr4_-_45820686	0.376	NM_173536	GABRG1	gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr1_+_234624266	0.376	NM_145861	EDARADD	EDAR-associated death domain
chr21_-_30460841	0.375	NM_012131	CLDN17	claudin 17
chr9_+_74956614	0.374		ANXA1	annexin A1
chr3_-_71262426	0.371		FOXP1	forkhead box P1
chr5_-_39430180	0.368		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr7_+_104539548	0.368		MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr4_+_96980261	0.367	NM_005390	PDHA2	pyruvate dehydrogenase (lipoamide) alpha 2
chr2_+_102401580	0.366	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr16_-_47872973	0.365		CBLN1	cerebellin 1 precursor
chr21_+_29439768	0.360		C21orf7	chromosome 21 open reading frame 7
chr19_+_56956264	0.359	NM_001005738	FPR2	formyl peptide receptor 2
chr17_-_51155073	0.359	NM_018286	TMEM100	transmembrane protein 100
chr10_+_4995685	0.358		AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr21_-_26175068	0.356		APP	amyloid beta (A4) precursor protein
chr10_+_44726635	0.354	NM_001123376	TMEM72	transmembrane protein 72
chr16_-_47873183	0.354	NM_004352	CBLN1	cerebellin 1 precursor
chr5_+_34723420	0.353	NM_001145523	RAI14	retinoic acid induced 14
chr13_-_40454188	0.351		ELF1	E74-like factor 1 (ets domain transcription factor)
chr11_-_64484184	0.350	NM_001037225	C11orf85	chromosome 11 open reading frame 85
chr2_-_61618165	0.350		XPO1	exportin 1 (CRM1 homolog, yeast)
chr11_+_59564323	0.348	NM_173801	PLAC1L	placenta-specific 1-like
chr1_-_160613203	0.347	NM_182581	C1orf111	chromosome 1 open reading frame 111
chr10_-_32707549	0.347		EPC1	enhancer of polycomb homolog 1 (Drosophila)
chr2_+_108571336	0.345	NM_001193488	LIMS1	LIM and senescent cell antigen-like domains 1
chr6_-_101018271	0.341	NM_005068	SIM1	single-minded homolog 1 (Drosophila)
chr1_+_51208499	0.340		CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr3_-_196792059	0.340		APOD	apolipoprotein D
chr7_-_25234582	0.339	NM_022150	NPVF	neuropeptide VF precursor
chr3_+_69895310	0.338	NM_001184967	MITF	microphthalmia-associated transcription factor
chr3_-_71262405	0.337		FOXP1	forkhead box P1
chr17_-_64462976	0.336	NM_007168	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr1_+_86662356	0.336	NM_006536	CLCA2	chloride channel accessory 2
chr2_-_68952006	0.335	NM_014482	BMP10	bone morphogenetic protein 10
chr5_+_60969392	0.333	NM_173667	FLJ37543	hypothetical protein FLJ37543

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.57	1.15e-15	GO:0007606	sensory perception of chemical stimulus
2.61	1.50e-14	GO:0007608	sensory perception of smell
2.06	1.76e-13	GO:0007600	sensory perception
1.66	5.43e-09	GO:0050877	neurological system process
1.57	1.21e-08	GO:0003008	system process
1.25	1.79e-06	GO:0032501	multicellular organismal process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.21	8.10e-04	GO:0071944	cell periphery
1.21	1.32e-03	GO:0005886	plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.68	1.57e-15	GO:0004984	olfactory receptor activity
1.97	2.21e-12	GO:0004930	G-protein coupled receptor activity
1.69	5.09e-10	GO:0004888	transmembrane receptor activity
1.51	9.00e-08	GO:0004872	receptor activity
1.38	3.10e-05	GO:0004871	signal transducer activity
1.38	3.10e-05	GO:0060089	molecular transducer activity