Motif ID: ATF5_CREB3.p2

Z-value: 2.579


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB3chr9_+_357222070.655.9e-03Click!
ATF5chr19_+_55123770-0.457.8e-02Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_32610161 5.516 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr5_-_138238877 3.191 LRRTM2
leucine rich repeat transmembrane neuronal 2
chr5_-_138238891 3.189 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr4_+_113777568 2.937 NM_016648
LARP7
La ribonucleoprotein domain family, member 7
chr4_-_113777470 2.901 C4orf21
chromosome 4 open reading frame 21
chr1_+_99502655 2.713 LPPR4
lipid phosphate phosphatase-related protein type 4
chr9_+_17568952 2.684 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr5_-_138238953 2.676 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr5_+_159276317 2.459 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr22_-_42589543 2.447 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr20_+_10147455 2.430 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr4_-_187884721 2.425


chr9_+_35528890 2.277 RUSC2
RUN and SH3 domain containing 2
chr6_+_89848229 2.187 PNRC1
proline-rich nuclear receptor coactivator 1
chr10_-_113933457 2.185 NM_020918
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr6_-_15356865 2.130


chr14_+_100362236 2.048 MEG3
maternally expressed 3 (non-protein coding)
chr1_-_79244948 2.011 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr3_+_62279707 2.000 C3orf14
chromosome 3 open reading frame 14
chr5_-_58607673 1.993 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_+_100362204 1.985 MEG3
maternally expressed 3 (non-protein coding)
chr18_+_29412538 1.983 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr4_-_113777569 1.974 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr7_+_38184444 1.954 NM_032016
STARD3NL
STARD3 N-terminal like
chr20_+_19903778 1.944 RIN2
Ras and Rab interactor 2
chr4_+_158216631 1.944 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr2_-_216944911 1.942 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr5_+_50714996 1.913 ISL1
ISL LIM homeobox 1
chr7_-_44992729 1.910 C7orf40
chromosome 7 open reading frame 40
chr9_-_124066838 1.908 RBM18
RNA binding motif protein 18
chr5_+_56505412 1.885 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr5_-_72896964 1.860 ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr4_-_186693574 1.847 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr9_+_35528628 1.847 NM_001135999
RUSC2
RUN and SH3 domain containing 2
chr7_+_97199206 1.845 NM_003182
NM_013996
NM_013997
NM_013998
TAC1



tachykinin, precursor 1



chr9_-_124066901 1.826 NM_033117
RBM18
RNA binding motif protein 18
chr5_+_72897323 1.818 NM_032175
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr14_-_22458199 1.811 RBM23
RNA binding motif protein 23
chr7_-_27120015 1.802 HOXA3
homeobox A3
chrX_-_83329562 1.799 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr2_-_198248828 1.772 NM_144629
RFTN2
raftlin family member 2
chr5_-_50714836 1.761 LOC642366
hypothetical LOC642366
chr5_-_72897132 1.758 NM_023039
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr12_-_81276285 1.746 NM_014167
CCDC59
coiled-coil domain containing 59
chr12_-_21818881 1.743 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr6_+_108593907 1.739 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr18_-_29412148 1.739


chr3_-_64186151 1.729 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr5_-_59100194 1.709 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_-_22458220 1.698 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr7_+_38184375 1.685 STARD3NL
STARD3 N-terminal like
chr4_-_111777584 1.681 PITX2
paired-like homeodomain 2
chr11_+_12652427 1.666 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr17_+_55051818 1.660 NM_004859
CLTC
clathrin, heavy chain (Hc)
chr12_+_97511805 1.653 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr3_+_101462375 1.645 NM_018309
TBC1D23
TBC1 domain family, member 23
chr4_-_111763655 1.639 NM_000325
PITX2
paired-like homeodomain 2
chr4_+_175441402 1.621 NM_001040157
KIAA1712
KIAA1712
chr14_-_22458134 1.603 RBM23
RNA binding motif protein 23
chr4_-_175441192 1.601 FBXO8
F-box protein 8
chr12_-_50871953 1.599 NM_001081492
NM_182507
KRT80

keratin 80

chr8_-_93181091 1.580 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_151746589 1.567 SERP1
stress-associated endoplasmic reticulum protein 1
chr7_+_38184393 1.561 STARD3NL
STARD3 N-terminal like
chr8_-_17148637 1.560 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr5_-_59100091 1.552 PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_+_37748031 1.545 SSTR1
somatostatin receptor 1
chr3_+_185538998 1.544 FAM131A
family with sequence similarity 131, member A
chr4_-_111777651 1.536 PITX2
paired-like homeodomain 2
chr3_+_151608673 1.533 TSC22D2
TSC22 domain family, member 2
chr4_+_134289893 1.519 NM_020815
NM_032961
PCDH10

protocadherin 10

chr7_+_27191534 1.519 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr7_+_38184363 1.513 STARD3NL
STARD3 N-terminal like
chr9_+_124066973 1.505 MRRF
mitochondrial ribosome recycling factor
chr8_+_40130143 1.499 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr8_+_134272463 1.483 NM_003882
NM_080838
WISP1

WNT1 inducible signaling pathway protein 1

chr4_+_145786622 1.483 NM_022475
HHIP
hedgehog interacting protein
chr8_-_17148474 1.475 CNOT7
CCR4-NOT transcription complex, subunit 7
chr19_-_55671814 1.468 NM_138411
FAM71E1
family with sequence similarity 71, member E1
chr1_+_156229934 1.465 KIRREL
kin of IRRE like (Drosophila)
chr5_-_95794416 1.462 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr6_+_39868126 1.457 DAAM2
dishevelled associated activator of morphogenesis 2
chr8_+_64243741 1.453 YTHDF3
YTH domain family, member 3
chr1_-_243092581 1.449 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr8_-_117837240 1.442 NM_003756
EIF3H
eukaryotic translation initiation factor 3, subunit H
chr4_-_80079393 1.424 NM_001040202
PAQR3
progestin and adipoQ receptor family member III
chr4_-_170770111 1.419 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr8_-_24869945 1.413 NM_006158
NEFL
neurofilament, light polypeptide
chr5_+_50714714 1.409 NM_002202
ISL1
ISL LIM homeobox 1
chr13_+_47776026 1.408 RB1
retinoblastoma 1
chrX_-_83644054 1.404 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr6_+_39868116 1.404


chr3_+_189354167 1.369 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr8_-_117837224 1.357 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr1_+_156229686 1.354 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr8_+_17148755 1.353 NM_001145152
NM_152415
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr8_+_64243662 1.350 NM_152758
YTHDF3
YTH domain family, member 3
chr3_-_49105905 1.348 QRICH1
glutamine-rich 1
chr11_+_116575249 1.338 NM_001001522
NM_003186
TAGLN

transgelin

chrX_+_101910713 1.337 LOC100287765
hypothetical LOC100287765
chr8_-_117837202 1.332 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr5_-_168660293 1.325 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr12_+_81276406 1.320 NM_032230
C12orf26
chromosome 12 open reading frame 26
chr2_+_105320440 1.318 NM_024093
C2orf49
chromosome 2 open reading frame 49
chr16_+_85169615 1.316 NM_005250
FOXL1
forkhead box L1
chr9_+_111582317 1.289 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr3_-_192063158 1.286 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr5_-_89861048 1.278 NM_198273
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr6_-_106880300 1.264 NM_004849
ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr4_-_56948345 1.239 NM_181806
AASDH
aminoadipate-semialdehyde dehydrogenase
chr10_-_118022965 1.230 NM_005264
GFRA1
GDNF family receptor alpha 1
chr5_+_14493905 1.227 TRIO
triple functional domain (PTPRF interacting)
chr6_-_106880229 1.221 ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr1_-_148868535 1.218 ENSA
endosulfine alpha
chr3_+_44778284 1.211 KIF15
kinesin family member 15
chr4_+_160408447 1.210 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr7_-_45095017 1.209 NM_001146334
NACAD
NAC alpha domain containing
chr2_+_108637916 1.196 LIMS1
LIMS3
LIM and senescent cell antigen-like domains 1
LIM and senescent cell antigen-like domains 3
chr7_-_140270749 1.195 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chrX_-_13866565 1.191 NM_001001994
GPM6B
glycoprotein M6B
chr12_+_67290951 1.186 RAP1B
RAP1BL
RAP1B, member of RAS oncogene family
RAP1B, member of RAS oncogene family pseudogene
chr4_-_156517423 1.186 MAP9
microtubule-associated protein 9
chr1_+_84539876 1.185 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr6_+_148705817 1.183 SASH1
SAM and SH3 domain containing 1
chr7_-_156378382 1.180 LMBR1
limb region 1 homolog (mouse)
chr4_+_170778265 1.177 NM_001829
NM_173872
CLCN3

chloride channel 3

chr4_-_156517394 1.177 MAP9
microtubule-associated protein 9
chr1_+_85300580 1.175 NM_145172
WDR63
WD repeat domain 63
chr16_+_1524162 1.172 NM_024600
TMEM204
transmembrane protein 204
chr4_-_104860277 1.171 NM_001059
TACR3
tachykinin receptor 3
chr12_-_21985433 1.168 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr7_+_22733626 1.168 IL6
interleukin 6 (interferon, beta 2)
chr22_+_29886224 1.163 RNF185
ring finger protein 185
chr11_-_62233552 1.158 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr9_-_78710698 1.147 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr12_+_70435176 1.143 RAB21
RAB21, member RAS oncogene family
chr1_-_16355013 1.142 NM_004431
EPHA2
EPH receptor A2
chr7_+_22733290 1.141 NM_000600
IL6
interleukin 6 (interferon, beta 2)
chr6_-_90119008 1.140 UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr4_-_163304567 1.138 NM_001128427
NM_001128428
NM_020116
FSTL5


follistatin-like 5


chrX_+_100692071 1.134 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr6_-_166321516 1.133 C6orf176
chromosome 6 open reading frame 176
chr3_-_8518327 1.123 LOC100288428
hypothetical LOC100288428
chr7_-_27191287 1.105 NM_005523
HOXA11
homeobox A11
chr3_-_189354510 1.095 LOC339929
hypothetical LOC339929
chr14_-_49122813 1.095 NM_001030001
NM_001032
RPS29

ribosomal protein S29

chr6_+_136214495 1.093 NM_018945
PDE7B
phosphodiesterase 7B
chr4_+_8493396 1.092 NM_152544
METTL19
methyltransferase like 19
chr19_+_43572679 1.090 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chr4_+_75529716 1.086 NM_001657
AREG
amphiregulin
chr4_-_156517544 1.085 NM_001039580
MAP9
microtubule-associated protein 9
chr1_+_36462583 1.084 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr6_-_166321393 1.083 C6orf176
chromosome 6 open reading frame 176
chr4_+_170778303 1.083 CLCN3
chloride channel 3
chr4_+_81337663 1.082 NM_001099403
PRDM8
PR domain containing 8
chr14_-_44500840 1.080 KLHL28
kelch-like 28 (Drosophila)
chr1_-_31883051 1.080 PEF1
penta-EF-hand domain containing 1
chr1_+_99502435 1.079 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr8_-_74953626 1.078 UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr12_-_113330574 1.077 NM_000192
NM_080717
TBX5

T-box 5

chr5_+_99899133 1.068 FAM174A
family with sequence similarity 174, member A
chr7_-_156378636 1.067 NM_022458
LMBR1
limb region 1 homolog (mouse)
chr8_+_118602134 1.063 NM_080651
MED30
mediator complex subunit 30
chr12_+_67290975 1.062 RAP1B
RAP1B, member of RAS oncogene family
chr17_-_46553083 1.060 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr11_-_62233600 1.060 NM_001130702
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_+_178867796 1.058 XPR1
xenotropic and polytropic retrovirus receptor 1
chr14_-_79748273 1.057 NM_000793
NM_013989
DIO2

deiodinase, iodothyronine, type II

chr8_+_118602151 1.054 MED30
mediator complex subunit 30
chr1_-_184916044 1.051 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr8_-_74953604 1.047 UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr11_+_66367458 1.046 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr14_-_44500871 1.046 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr10_+_93673544 1.043 NM_003972
BTAF1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)
chr1_+_161305558 1.042 NM_001113381
RGS4
regulator of G-protein signaling 4
chr3_-_102878301 1.041 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr8_-_74953632 1.038 UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr2_+_108637698 1.036 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr12_+_61147083 1.034 MON2
MON2 homolog (S. cerevisiae)
chr1_+_184611512 1.034 NM_001164245
NM_001164246
NM_017847
C1orf27


chromosome 1 open reading frame 27


chr4_-_111763356 1.033 PITX2
paired-like homeodomain 2
chr1_+_36462625 1.032 THRAP3
thyroid hormone receptor associated protein 3
chr14_+_99017485 1.029 NM_001099402
CCNK
cyclin K
chr6_-_106880222 1.020 ATG5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr3_+_130081187 1.011 ACAD9
acyl-CoA dehydrogenase family, member 9
chr8_+_26204997 1.007 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr12_-_14847675 1.005 WBP11
WW domain binding protein 11
chr12_+_67291016 0.996 RAP1B
RAP1B, member of RAS oncogene family
chr11_-_88864061 0.989 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr12_+_67290977 0.987 RAP1B
RAP1BL
RAP1B, member of RAS oncogene family
RAP1B, member of RAS oncogene family pseudogene
chr5_+_174084137 0.987 NM_002449
MSX2
msh homeobox 2
chr10_+_35524835 0.981 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chrX_-_131918905 0.973 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr11_-_35503720 0.972 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr1_-_152394215 0.970 NM_001159484
NM_207308
NUP210L

nucleoporin 210kDa-like

chr11_-_111255020 0.969 FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr4_-_24523605 0.969 NM_001130726
CCDC149
coiled-coil domain containing 149
chr2_+_238200922 0.962 NM_001137550
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr3_+_130081161 0.961 ACAD9
acyl-CoA dehydrogenase family, member 9
chr17_+_7096545 0.960 C17orf81
chromosome 17 open reading frame 81

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 5.95e-18 GO:0044260 cellular macromolecule metabolic process
1.33 1.37e-15 GO:0043170 macromolecule metabolic process
1.25 6.13e-13 GO:0044237 cellular metabolic process
1.23 5.50e-11 GO:0044238 primary metabolic process
1.43 2.98e-10 GO:0044267 cellular protein metabolic process
1.20 4.34e-09 GO:0008152 metabolic process
1.12 2.60e-08 GO:0009987 cellular process
1.34 1.19e-07 GO:0019538 protein metabolic process
1.39 3.67e-07 GO:0090304 nucleic acid metabolic process
1.43 6.15e-07 GO:0010467 gene expression
1.34 9.41e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 1.70e-06 GO:0051649 establishment of localization in cell
1.51 3.33e-06 GO:0051641 cellular localization
1.29 1.13e-05 GO:0034641 cellular nitrogen compound metabolic process
1.64 1.51e-05 GO:0046907 intracellular transport
1.42 1.52e-05 GO:0009059 macromolecule biosynthetic process
1.28 2.92e-05 GO:0006807 nitrogen compound metabolic process
1.41 3.06e-05 GO:0034645 cellular macromolecule biosynthetic process
1.24 2.62e-04 GO:0031323 regulation of cellular metabolic process
1.37 2.99e-04 GO:0016070 RNA metabolic process
1.25 3.59e-04 GO:0060255 regulation of macromolecule metabolic process
1.53 7.29e-04 GO:0045184 establishment of protein localization
1.27 8.47e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.54 9.10e-04 GO:0022402 cell cycle process
1.23 1.04e-03 GO:0080090 regulation of primary metabolic process
1.29 1.32e-03 GO:0044249 cellular biosynthetic process
1.21 1.76e-03 GO:0019222 regulation of metabolic process
1.46 1.76e-03 GO:0007049 cell cycle
1.51 2.09e-03 GO:0015031 protein transport
1.23 2.11e-03 GO:0071840 cellular component organization or biogenesis
1.33 2.68e-03 GO:0006464 protein modification process
1.35 3.68e-03 GO:0006996 organelle organization
1.28 3.98e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.27 4.27e-03 GO:0009058 biosynthetic process
1.31 5.00e-03 GO:0043412 macromolecule modification
1.27 6.41e-03 GO:0010556 regulation of macromolecule biosynthetic process
3.55 9.06e-03 GO:0006888 ER to Golgi vesicle-mediated transport
1.42 9.66e-03 GO:0008104 protein localization
1.58 1.02e-02 GO:0000278 mitotic cell cycle
1.25 1.07e-02 GO:0071842 cellular component organization at cellular level
1.25 1.44e-02 GO:0031326 regulation of cellular biosynthetic process
2.88 1.45e-02 GO:0034138 toll-like receptor 3 signaling pathway
1.52 1.51e-02 GO:0022403 cell cycle phase
2.73 1.54e-02 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
1.24 1.64e-02 GO:0009889 regulation of biosynthetic process
2.23 1.66e-02 GO:0048193 Golgi vesicle transport
1.21 1.80e-02 GO:0016043 cellular component organization
1.69 2.32e-02 GO:0006886 intracellular protein transport
2.80 2.53e-02 GO:0002756 MyD88-independent toll-like receptor signaling pathway
1.45 3.61e-02 GO:0033554 cellular response to stress
1.24 3.71e-02 GO:0010468 regulation of gene expression
1.35 4.30e-02 GO:0033036 macromolecule localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 1.91e-22 GO:0044424 intracellular part
1.15 4.59e-21 GO:0005622 intracellular
1.21 5.07e-19 GO:0043231 intracellular membrane-bounded organelle
1.21 5.15e-19 GO:0043227 membrane-bounded organelle
1.19 8.30e-19 GO:0043229 intracellular organelle
1.19 1.93e-18 GO:0043226 organelle
1.20 9.08e-15 GO:0005737 cytoplasm
1.27 1.81e-13 GO:0005634 nucleus
1.25 2.13e-11 GO:0044422 organelle part
1.25 4.18e-11 GO:0044446 intracellular organelle part
1.44 2.46e-10 GO:0044428 nuclear part
1.20 6.40e-08 GO:0044444 cytoplasmic part
1.42 1.22e-07 GO:0031981 nuclear lumen
1.28 4.55e-07 GO:0032991 macromolecular complex
1.36 6.18e-07 GO:0070013 intracellular organelle lumen
1.35 7.80e-07 GO:0043233 organelle lumen
1.34 1.50e-06 GO:0031974 membrane-enclosed lumen
1.36 3.27e-06 GO:0005829 cytosol
1.27 3.67e-05 GO:0043234 protein complex
1.40 1.80e-04 GO:0005654 nucleoplasm
7.57 1.06e-03 GO:0030127 COPII vesicle coat
3.55 1.48e-03 GO:0030120 vesicle coat
1.23 6.34e-03 GO:0043228 non-membrane-bounded organelle
1.23 6.34e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.45 2.88e-02 GO:0015630 microtubule cytoskeleton
1.42 4.78e-02 GO:0044451 nucleoplasm part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.23 4.89e-15 GO:0005515 protein binding
1.11 2.12e-11 GO:0005488 binding
1.72 6.13e-09 GO:0003723 RNA binding
1.39 1.11e-08 GO:0000166 nucleotide binding
1.41 3.25e-07 GO:0032553 ribonucleotide binding
1.41 3.25e-07 GO:0032555 purine ribonucleotide binding
1.41 3.36e-07 GO:0035639 purine ribonucleoside triphosphate binding
1.40 3.81e-07 GO:0017076 purine nucleotide binding
1.42 7.98e-06 GO:0032559 adenyl ribonucleotide binding
1.42 8.31e-06 GO:0030554 adenyl nucleotide binding
1.42 1.26e-05 GO:0005524 ATP binding
1.24 2.36e-04 GO:0003676 nucleic acid binding
2.07 5.74e-03 GO:0000287 magnesium ion binding
1.46 5.79e-03 GO:0016462 pyrophosphatase activity
1.46 7.07e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.45 8.61e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.43 2.64e-02 GO:0017111 nucleoside-triphosphatase activity
2.18 2.91e-02 GO:0051082 unfolded protein binding