Motif ID: BACH2.p2

Z-value: 1.280


Transcription factors associated with BACH2.p2:

Gene SymbolEntrez IDGene Name
BACH2 60468 BTB and CNC homology 1, basic leucine zipper transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BACH2chr6_-_910633010.533.3e-02Click!


Activity profile for motif BACH2.p2.

activity profile for motif BACH2.p2


Sorted Z-values histogram for motif BACH2.p2

Sorted Z-values for motif BACH2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BACH2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_384238 3.732 PKP3
plakophilin 3
chr3_-_197549640 3.608 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr4_-_977163 3.143 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr11_+_384199 3.140 NM_007183
PKP3
plakophilin 3
chr3_-_197549588 3.108 TM4SF19
transmembrane 4 L six family member 19
chr17_-_40858775 3.101 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr12_-_51629874 2.776 KRT8
keratin 8
chr1_-_156923111 2.433 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr22_+_43451600 2.403 PRR5
proline rich 5 (renal)
chr6_-_31853027 2.402 NM_025258
C6orf27
chromosome 6 open reading frame 27
chrX_+_30143595 2.370 NM_002364
MAGEB2
melanoma antigen family B, 2
chr1_-_1679940 2.251 NM_001198995
NADK
NAD kinase
chr7_+_72883128 2.126 NM_001305
CLDN4
claudin 4
chr1_-_108032645 2.068 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr1_+_153232685 2.048 NM_018655
LENEP
lens epithelial protein
chr17_-_39700960 2.016 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr19_+_7859380 2.014 NM_025061
LRRC8E
leucine rich repeat containing 8 family, member E
chr1_-_160648429 1.926 NM_053282
SH2D1B
SH2 domain containing 1B
chr7_+_150319076 1.899 NM_000603
NOS3
nitric oxide synthase 3 (endothelial cell)
chr11_+_2881080 1.835 SLC22A18
solute carrier family 22, member 18
chr17_-_53764867 1.755


chr20_+_42463419 1.695 HNF4A
hepatocyte nuclear factor 4, alpha
chr19_+_43486640 1.680 NM_033520
C19orf33
chromosome 19 open reading frame 33
chr3_-_180460372 1.675 NM_171829
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr19_+_55398680 1.654 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr18_+_54039818 1.616 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr16_-_11918019 1.569 NM_001130007
GSPT1
G1 to S phase transition 1
chr11_+_116205830 1.559 NM_000040
APOC3
apolipoprotein C-III
chr22_+_19191884 1.532 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr22_+_21393107 1.522 IGLJ3
immunoglobulin lambda joining 3
chr5_+_76181581 1.513 NM_130772
S100Z
S100 calcium binding protein Z
chr18_+_54039779 1.505 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr22_+_19191898 1.504 MED15
mediator complex subunit 15
chr22_+_19191875 1.492 MED15
mediator complex subunit 15
chr22_+_19191886 1.484 MED15
mediator complex subunit 15
chr16_+_29984611 1.475 ALDOA
aldolase A, fructose-bisphosphate
chr15_+_57691272 1.471 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_-_119499188 1.466 TRIM29
tripartite motif containing 29
chr6_-_149847718 1.464 ZC3H12D
zinc finger CCCH-type containing 12D
chr22_+_19191859 1.406 MED15
mediator complex subunit 15
chr20_+_42463387 1.398 HNF4A
hepatocyte nuclear factor 4, alpha
chr6_+_47774247 1.395 NM_153838
GPR115
G protein-coupled receptor 115
chr14_-_93924873 1.390 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr18_+_54039730 1.387 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr19_-_56215084 1.386 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr20_+_42463350 1.374 HNF4A
hepatocyte nuclear factor 4, alpha
chr7_-_150352484 1.362 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr15_+_57691382 1.358 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr16_+_29984544 1.353 NM_184041
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_29984591 1.352 ALDOA
aldolase A, fructose-bisphosphate
chr16_+_29984621 1.329 ALDOA
aldolase A, fructose-bisphosphate
chr20_+_41621119 1.324 SGK2
serum/glucocorticoid regulated kinase 2
chr14_-_93924663 1.323 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr8_+_22266256 1.322 PIWIL2
piwi-like 2 (Drosophila)
chr9_+_137593420 1.319 NM_001018049
NM_002571
PAEP

progestagen-associated endometrial protein

chr22_+_19191964 1.316 MED15
mediator complex subunit 15
chr16_-_30032330 1.311 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr1_+_17507276 1.306 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr6_-_31812049 1.301 CLIC1
chloride intracellular channel 1
chr8_-_144887876 1.298 NM_198488
FAM83H
family with sequence similarity 83, member H
chr22_+_43451351 1.296 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr6_-_32121784 1.254 NM_032470
TNXB
tenascin XB
chr6_-_31812072 1.249 CLIC1
chloride intracellular channel 1
chr9_-_139042526 1.248 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr12_+_54910767 1.226 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr17_+_77910411 1.222 NM_207459
TEX19
testis expressed 19
chr16_+_29984647 1.213 ALDOA
aldolase A, fructose-bisphosphate
chr2_+_169634330 1.208 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr19_-_55156118 1.207 NM_001135163
NM_052884
SIGLEC11

sialic acid binding Ig-like lectin 11

chrX_-_154216929 1.195 NM_001289
CLIC2
chloride intracellular channel 2
chr10_+_70745615 1.190 NM_033496
HK1
hexokinase 1
chr20_+_42463279 1.178 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr1_+_221966951 1.160 CAPN2
calpain 2, (m/II) large subunit
chr5_-_141041982 1.147 NM_022481
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr7_+_142788569 1.138 ZYX
zyxin
chr6_-_149847809 1.128 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr22_+_21464980 1.116


chr3_+_38363299 1.110 XYLB
xylulokinase homolog (H. influenzae)
chr9_-_139042416 1.101 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr22_-_22304486 1.091 NM_016449
C22orf43
chromosome 22 open reading frame 43
chr6_-_31812251 1.084 CLIC1
chloride intracellular channel 1
chr16_-_28515195 1.082 NM_177528
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr16_-_1369613 1.081 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr19_-_40696393 1.078 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr17_+_71229110 1.066 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr7_+_142788566 1.062 ZYX
zyxin
chrX_-_48787876 1.057 NM_006521
TFE3
transcription factor binding to IGHM enhancer 3
chr6_-_31812260 1.047 CLIC1
chloride intracellular channel 1
chr22_+_21495273 1.042


chr4_-_80548378 1.038 NM_033214
GK2
glycerol kinase 2
chrX_-_129072152 1.033 NM_001421
ELF4
E74-like factor 4 (ets domain transcription factor)
chr5_-_141041933 1.026 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr7_+_142788517 1.024 ZYX
zyxin
chr7_+_128219307 1.017 NM_022742
CCDC136
coiled-coil domain containing 136
chr7_+_142788579 1.004 ZYX
zyxin
chr7_+_142788521 1.001 ZYX
zyxin
chr6_-_31812266 0.997 CLIC1
chloride intracellular channel 1
chr17_+_69941430 0.997 NM_018653
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr19_+_43971689 0.991 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr19_+_61039755 0.989 NM_134444
NLRP4
NLR family, pyrin domain containing 4
chr16_+_28413421 0.985 NM_018690
APOBR
apolipoprotein B receptor
chr3_+_38363292 0.985 XYLB
xylulokinase homolog (H. influenzae)
chr2_+_68726457 0.984 NM_138964
PROKR1
prokineticin receptor 1
chr1_+_36394338 0.978 NM_018067
MAP7D1
MAP7 domain containing 1
chr6_+_32229278 0.975 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr1_+_17719405 0.973 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr16_-_31068882 0.971 NM_173502
PRSS36
protease, serine, 36
chr6_-_31812283 0.968 CLIC1
chloride intracellular channel 1
chr6_-_31812214 0.966 CLIC1
chloride intracellular channel 1
chr6_+_150112537 0.958 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chrX_-_76824726 0.956 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr19_-_61039939 0.955 NM_145007
NLRP11
NLR family, pyrin domain containing 11
chr1_-_6585268 0.950 KLHL21
kelch-like 21 (Drosophila)
chr11_-_102331643 0.948 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr17_+_71229151 0.947 ITGB4
integrin, beta 4
chr6_-_31812297 0.944 NM_001288
CLIC1
chloride intracellular channel 1
chr14_-_23847000 0.943 CIDEB
cell death-inducing DFFA-like effector b
chr18_+_9875722 0.938 NM_001098529
NM_032243
TXNDC2

thioredoxin domain containing 2 (spermatozoa)

chr3_-_9895633 0.928 NM_022094
CIDEC
cell death-inducing DFFA-like effector c
chr3_+_38363226 0.924 NM_005108
XYLB
xylulokinase homolog (H. influenzae)
chr19_-_54350457 0.922 NM_002152
HRC
histidine rich calcium binding protein
chrX_-_15198093 0.922 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr17_-_70480385 0.914 NM_030630
C17orf28
chromosome 17 open reading frame 28
chr1_+_221966849 0.906 CAPN2
calpain 2, (m/II) large subunit
chr1_+_221966835 0.901 CAPN2
calpain 2, (m/II) large subunit
chr1_+_221966684 0.894 NM_001748
CAPN2
calpain 2, (m/II) large subunit
chr2_+_28469275 0.890 NM_005253
FOSL2
FOS-like antigen 2
chr7_+_149696263 0.889 REPIN1
replication initiator 1
chr7_+_142788480 0.887 NM_001010972
NM_003461
ZYX

zyxin

chr11_+_44026106 0.886 NM_001031854
ACCSL
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like
chr6_+_131190237 0.885 NM_001195597
LOC285733
hypothetical LOC285733
chr3_-_127258299 0.881 NM_001008487
SLC41A3
solute carrier family 41, member 3
chr22_-_41672990 0.880 NM_007229
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr6_+_150112511 0.878 NM_005389
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr6_+_44302973 0.871 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr2_-_238164042 0.869 RAB17
RAB17, member RAS oncogene family
chr19_-_56260135 0.867 NM_015596
KLK13
kallikrein-related peptidase 13
chr2_+_113591940 0.865 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chrX_-_129072103 0.862 ELF4
E74-like factor 4 (ets domain transcription factor)
chr1_+_36394044 0.861 MAP7D1
MAP7 domain containing 1
chr10_-_88844666 0.856 NM_005271
GLUD1
glutamate dehydrogenase 1
chr14_-_23846904 0.844 CIDEB
cell death-inducing DFFA-like effector b
chr14_-_23847024 0.842 CIDEB
cell death-inducing DFFA-like effector b
chr14_-_23846993 0.842 CIDEB
cell death-inducing DFFA-like effector b
chr7_-_107430566 0.838 NM_002291
LAMB1
laminin, beta 1
chr22_+_21552897 0.833 LOC100290481
immunoglobulin lambda light chain-like
chr1_+_173111306 0.832 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr11_+_123600553 0.832 NM_001007249
OR8G2
olfactory receptor, family 8, subfamily G, member 2
chr19_+_63386603 0.829 ZNF274
zinc finger protein 274
chr1_+_154351082 0.824 NM_005572
NM_170707
NM_170708
LMNA


lamin A/C


chrX_-_48787696 0.820 TFE3
transcription factor binding to IGHM enhancer 3
chr5_+_179180517 0.816 SQSTM1
sequestosome 1
chr2_+_47449951 0.810 EPCAM
epithelial cell adhesion molecule
chr16_-_4604781 0.809 FAM100A
family with sequence similarity 100, member A
chr22_+_21079355 0.796


chr6_+_43705254 0.794 NM_001003690
MAD2L1BP
MAD2L1 binding protein
chr5_+_179180509 0.792 SQSTM1
sequestosome 1
chr1_-_93030538 0.788 NM_005665
EVI5
ecotropic viral integration site 5
chr5_-_137117873 0.787 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr5_-_179040580 0.785 NM_001164444
CBY3
chibby homolog 3 (Drosophila)
chr6_+_25760352 0.785 NM_006998
SCGN
secretagogin, EF-hand calcium binding protein
chr4_+_76700281 0.785 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr5_-_137117770 0.777 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr19_-_48977247 0.777 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_-_6585485 0.777 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chr9_+_139041736 0.775 NM_207511
C9orf139
chromosome 9 open reading frame 139
chr17_+_71229191 0.773 ITGB4
integrin, beta 4
chr10_-_21503025 0.772 NM_001173484
NM_213569
NEBL

nebulette

chr16_+_88515917 0.772 NM_001197181
TUBB3
tubulin, beta 3
chr17_+_71109734 0.771 MYO15B
myosin XVB pseudogene
chr19_-_48976852 0.765 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr2_-_85494639 0.758 CAPG
capping protein (actin filament), gelsolin-like
chr5_-_137117539 0.758 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr5_-_137117936 0.753 NM_006805
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr5_-_137117932 0.752 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr3_-_9895471 0.752 CIDEC
cell death-inducing DFFA-like effector c
chr1_-_28392966 0.747 NM_001164722
NM_001164721
PTAFR

platelet-activating factor receptor

chr11_+_74548472 0.745 NM_001145211
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr17_-_57023322 0.742 NM_199290
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr10_-_42507180 0.735


chr8_-_26780665 0.735 ADRA1A
adrenergic, alpha-1A-, receptor
chr11_-_118571793 0.731 NM_001145018
CCDC153
coiled-coil domain containing 153
chr22_+_21116283 0.730


chr5_+_179180447 0.728 NM_003900
SQSTM1
sequestosome 1
chr2_-_55131176 0.726 RTN4
reticulon 4
chr19_+_45564549 0.725 PLD3
phospholipase D family, member 3
chr7_+_102078007 0.715 NM_001166339
NM_001031618
SPDYE2L
SPDYE2
WBSCR19-like protein 3
speedy homolog E2 (Xenopus laevis)
chr12_+_50981915 0.712 NM_002284
KRT86
keratin 86
chrX_-_129072333 0.710 NM_001127197
ELF4
E74-like factor 4 (ets domain transcription factor)
chrX_+_65299157 0.709 NM_138737
HEPH
hephaestin
chr19_+_55164668 0.708 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr17_-_36165050 0.708 NM_181534
KRT25
keratin 25
chr7_+_30927439 0.707 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr2_+_47449790 0.703 NM_002354
EPCAM
epithelial cell adhesion molecule
chr13_-_40491405 0.702 ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_-_11841476 0.700 NM_002521
NPPB
natriuretic peptide B
chr5_-_137117948 0.699


chr11_+_5916033 0.697


chr10_-_21502993 0.697 NEBL
nebulette
chr22_+_20715340 0.689



Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
8.16 2.32e-02 GO:0004198 calcium-dependent cysteine-type endopeptidase activity