Motif ID: CDC5L.p2

Z-value: 1.271


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CDC5Lchr6_+_444632650.234.0e-01Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_138238877 4.082 LRRTM2
leucine rich repeat transmembrane neuronal 2
chr7_-_13992351 3.837 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr5_-_138238891 3.650 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr5_-_138238953 2.577 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr14_+_38772870 2.535 NM_054024
MIA2
melanoma inhibitory activity 2
chr8_+_75899326 1.674 NM_015886
PI15
peptidase inhibitor 15
chr2_-_162808123 1.605 NM_004460
FAP
fibroblast activation protein, alpha
chr13_-_37070862 1.189 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr1_+_194887630 1.099 NM_000186
NM_001014975
CFH

complement factor H

chr12_+_18305740 1.063 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr13_-_85271329 1.057 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr3_-_139315011 0.926 NM_001170538
DZIP1L
DAZ interacting protein 1-like
chr1_-_20682541 0.888


chr6_-_112001590 0.887 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr4_+_120168002 0.774 SYNPO2
synaptopodin 2
chr4_-_159313167 0.751 NM_016613
FAM198B
family with sequence similarity 198, member B
chr18_+_59593591 0.745 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr6_-_116973465 0.725 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr9_+_129066576 0.716 NM_032293
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr14_-_80934523 0.692 NM_033104
STON2
stonin 2
chr11_+_27019084 0.666 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chrX_-_15312390 0.660 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr4_+_120167950 0.636 SYNPO2
synaptopodin 2
chr4_+_53986759 0.633 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr7_+_110518297 0.606 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr3_-_156876798 0.599 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr17_-_7434113 0.589 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr17_-_64649608 0.587 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr12_+_16391795 0.583 NM_020300
NM_145791
MGST1

microsomal glutathione S-transferase 1

chr2_+_151922350 0.581 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr10_+_111755715 0.573 NM_019903
ADD3
adducin 3 (gamma)
chr2_+_214984705 0.557 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr18_-_35634247 0.551 LOC647946
hypothetical LOC647946
chrX_-_15593074 0.550 NM_020665
TMEM27
transmembrane protein 27
chr9_-_94338072 0.540 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr4_+_41309482 0.539 LIMCH1
LIM and calponin homology domains 1
chr7_-_16471817 0.537 NM_015464
SOSTDC1
sclerostin domain containing 1
chr4_+_128773529 0.527 NM_015693
INTU
inturned planar cell polarity effector homolog (Drosophila)
chr4_-_186537145 0.521 NM_018409
LRP2BP
LRP2 binding protein
chr5_-_125956996 0.512 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr5_+_140494971 0.504 NM_015669
PCDHB5
protocadherin beta 5
chr5_+_140160966 0.502 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr1_+_19807168 0.498


chr11_+_101488380 0.487 NM_001195045
YAP1
Yes-associated protein 1
chr4_+_74825138 0.485 NM_000584
IL8
interleukin 8
chr21_-_35174742 0.478 RUNX1
runt-related transcription factor 1
chr22_-_43987010 0.478 NM_015264
KIAA0930
KIAA0930
chr5_+_140751666 0.475 NM_014004
NM_032088
PCDHGA8

protocadherin gamma subfamily A, 8

chr15_+_30721161 0.460 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr4_+_41309690 0.454 LIMCH1
LIM and calponin homology domains 1
chr5_+_156540425 0.453 NM_005546
ITK
IL2-inducible T-cell kinase
chr3_-_110155237 0.446 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr19_-_10558906 0.446 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr4_+_41309668 0.443 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr3_+_142175329 0.426 SLC25A36
solute carrier family 25, member 36
chr2_+_165858586 0.423 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr1_-_180624380 0.423 GLUL
glutamate-ammonia ligase
chr12_+_56802 0.419 NM_015232
IQSEC3
IQ motif and Sec7 domain 3
chr6_+_7347878 0.407 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr4_-_23500706 0.404 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr5_+_145297490 0.401 SH3RF2
SH3 domain containing ring finger 2
chr2_-_225078931 0.400 CUL3
cullin 3
chr12_-_15706340 0.389 EPS8
epidermal growth factor receptor pathway substrate 8
chr4_+_95595419 0.385 PDLIM5
PDZ and LIM domain 5
chr2_+_166034402 0.384 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr1_+_195503956 0.382 NM_001193640
NM_201253
CRB1

crumbs homolog 1 (Drosophila)

chr7_-_122126422 0.380 NM_139175
RNF133
ring finger protein 133
chr3_-_113495763 0.377 NM_183061
SLC9A10
solute carrier family 9, member 10
chr2_-_162717159 0.375 NM_002054
GCG
glucagon
chr5_+_147775652 0.369 FBXO38
F-box protein 38
chr3_-_64647325 0.367 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr7_+_143043871 0.367 NM_001130026
FAM115C
family with sequence similarity 115, member C
chr16_-_45562840 0.365 DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr13_+_51496679 0.354 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr12_+_97513644 0.354 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr1_+_151270301 0.352 NM_003125
SPRR1B
small proline-rich protein 1B
chr1_+_43063817 0.351 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr6_+_132000134 0.345 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr22_-_34564611 0.342 RPL41P5
ribosomal protein L41 pseudogene 5
chr4_-_110942576 0.342 CFI
complement factor I
chr9_+_35663852 0.337 NM_001216
CA9
carbonic anhydrase IX
chr4_-_87247829 0.332 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr11_+_111552298 0.332 NM_001037290
BCO2
beta-carotene oxygenase 2
chr10_+_5126589 0.330 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_-_203592538 0.328 NM_018203
KLHDC8A
kelch domain containing 8A
chr9_+_5880801 0.328 NM_005511
MLANA
melan-A
chr7_-_113346284 0.315 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr6_+_125346208 0.315 NM_152553
RNF217
ring finger protein 217
chr3_+_85858321 0.314 NM_153184
CADM2
cell adhesion molecule 2
chrX_-_19598912 0.314 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr3_+_137224266 0.309 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr3_-_124822113 0.307 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr10_+_5126556 0.307 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr12_+_16397617 0.306 NM_145764
MGST1
microsomal glutathione S-transferase 1
chr1_+_227506751 0.304 NM_006542
SPHAR
S-phase response (cyclin related)
chr9_+_674193 0.301


chr13_-_98428244 0.296 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr2_-_61098867 0.295 NM_144709
PUS10
pseudouridylate synthase 10
chr22_-_37044034 0.294 NM_001894
CSNK1E
casein kinase 1, epsilon
chr11_-_83706027 0.293 DLG2
discs, large homolog 2 (Drosophila)
chr1_-_180624494 0.291 GLUL
glutamate-ammonia ligase
chr4_+_69465107 0.290 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr5_+_140200995 0.288 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr5_+_140568451 0.288 NM_018932
PCDHB12
protocadherin beta 12
chr10_+_49279647 0.286 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr10_+_5126613 0.282 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr8_-_15140162 0.281 NM_139167
SGCZ
sarcoglycan, zeta
chr6_-_119137923 0.280 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr5_+_145296313 0.280 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr21_+_29439768 0.279 C21orf7
chromosome 21 open reading frame 7
chr8_+_50987149 0.278 NM_018967
SNTG1
syntrophin, gamma 1
chr22_-_34566367 0.275 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr21_-_30774502 0.274 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr17_-_57023322 0.271 NM_199290
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr21_-_30460841 0.271 NM_012131
CLDN17
claudin 17
chr4_-_70760381 0.269 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr1_-_202402043 0.268 NM_000537
REN
renin
chr1_+_10432362 0.267 NM_001302
CORT
cortistatin
chr20_-_9767406 0.266 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr3_-_131081910 0.265 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr10_-_69267774 0.265 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr2_+_73973640 0.262 ACTG2
actin, gamma 2, smooth muscle, enteric
chr4_-_186969041 0.259 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr11_+_110631916 0.256 NM_198498
C11orf53
chromosome 11 open reading frame 53
chr7_+_80145461 0.256 CD36
CD36 molecule (thrombospondin receptor)
chr2_-_21106291 0.255 APOB
apolipoprotein B (including Ag(x) antigen)
chr4_-_15549047 0.254 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr6_+_12825818 0.254 NM_030948
PHACTR1
phosphatase and actin regulator 1
chr4_+_86968069 0.251 ARHGAP24
Rho GTPase activating protein 24
chr4_-_186814852 0.250 SORBS2
sorbin and SH3 domain containing 2
chr3_+_50281582 0.248 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr14_+_69307914 0.244 SRSF5
serine/arginine-rich splicing factor 5
chr1_+_84382575 0.244 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chrX_-_114703273 0.242


chr3_+_191588354 0.242 NM_006580
CLDN16
claudin 16
chr8_-_7710547 0.241 NM_001037668
NM_001040705
DEFB107A
DEFB107B
defensin, beta 107A
defensin, beta 107B
chr5_+_140719773 0.238 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr5_+_92944680 0.237 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_-_120112989 0.235 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr1_+_66230977 0.235 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_-_152431175 0.235 NM_152263
TPM3
tropomyosin 3
chr20_-_33706532 0.235 RBM12
RNA binding motif protein 12
chr11_-_5964790 0.233 NM_001005173
OR52L1
olfactory receptor, family 52, subfamily L, member 1
chr9_+_22436783 0.228 NM_022160
DMRTA1
DMRT-like family A1
chr12_-_52939636 0.227 NM_001127321
CBX5
chromobox homolog 5
chr1_+_246178701 0.227 NM_001001963
OR2L8
olfactory receptor, family 2, subfamily L, member 8
chr1_+_150902495 0.225 NM_178430
LCE2D
late cornified envelope 2D
chr14_+_19365447 0.225 NM_001004723
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr17_-_19231049 0.225 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr4_-_152368492 0.225 SH3D19
SH3 domain containing 19
chr2_-_75650355 0.223 NM_032181
FAM176A
family with sequence similarity 176, member A
chr11_+_129496792 0.223 APLP2
amyloid beta (A4) precursor-like protein 2
chr4_+_73116384 0.222 NM_004885
NPFFR2
neuropeptide FF receptor 2
chrX_+_36163971 0.221 NM_001098843
CXorf30
chromosome X open reading frame 30
chrX_-_118610880 0.219 NM_001173488
NKRF
NFKB repressing factor
chr6_-_71069347 0.218 NM_001851
COL9A1
collagen, type IX, alpha 1
chr7_-_26202626 0.218 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr20_+_31613800 0.217 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chrX_+_77052834 0.214 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chrX_+_102471769 0.214 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chr4_+_109033868 0.213 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr7_-_13996166 0.212 NM_001163147
NM_004956
ETV1

ets variant 1

chr6_-_155818728 0.212 NM_015718
NOX3
NADPH oxidase 3
chr6_+_55147029 0.211 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr8_-_122722674 0.210 NM_005328
HAS2
hyaluronan synthase 2
chr9_+_74956614 0.209 ANXA1
annexin A1
chr13_-_109600709 0.209 COL4A1
collagen, type IV, alpha 1
chr3_-_116272911 0.209 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr9_+_74956601 0.205 ANXA1
annexin A1
chr12_-_52939584 0.201 NM_001127322
CBX5
chromobox homolog 5
chr10_-_64698831 0.199 NM_004241
JMJD1C
jumonji domain containing 1C
chr2_-_160765008 0.199 ITGB6
integrin, beta 6
chr4_-_68793928 0.197 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr1_+_84382562 0.197 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_-_160764819 0.196 NM_000888
ITGB6
integrin, beta 6
chr2_+_33213111 0.196 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr11_+_111551417 0.195 NM_031938
BCO2
beta-carotene oxygenase 2
chr1_-_214963279 0.194 NM_001438
ESRRG
estrogen-related receptor gamma
chr3_+_187840842 0.193 NM_014375
FETUB
fetuin B
chr4_+_15080586 0.192 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr18_+_54039818 0.191 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr18_+_59405513 0.190 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr21_-_30796278 0.190 NM_181611
KRTAP19-5
keratin associated protein 19-5
chr7_-_88262966 0.189 NM_152706
C7orf62
chromosome 7 open reading frame 62
chr11_-_85107569 0.188 NM_206929
SYTL2
synaptotagmin-like 2
chr12_+_28301399 0.187 NM_018318
CCDC91
coiled-coil domain containing 91
chr17_-_36451189 0.186 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr3_+_115099007 0.186 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr12_-_21379098 0.185 NM_021094
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr3_-_95230143 0.185 NM_001001850
STX19
syntaxin 19
chr6_+_121798443 0.184 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr12_-_66905802 0.184 NM_018402
IL26
interleukin 26
chr2_+_73973600 0.184 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr2_-_192419896 0.183 SDPR
serum deprivation response
chr12_+_54011750 0.181 NM_054104
OR6C3
olfactory receptor, family 6, subfamily C, member 3
chr8_+_67568044 0.179 NM_152765
C8orf46
chromosome 8 open reading frame 46
chr1_-_242073094 0.179 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr1_+_40977092 0.178 NFYC
nuclear transcription factor Y, gamma
chr4_-_90197140 0.176 NM_014883
FAM13A
family with sequence similarity 13, member A
chr2_-_73781974 0.175 NM_016347
NAT8B
N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.36 5.28e-04 GO:0007608 sensory perception of smell
2.21 1.55e-03 GO:0007606 sensory perception of chemical stimulus
1.84 4.38e-03 GO:0007600 sensory perception
1.26 9.90e-03 GO:0032501 multicellular organismal process
1.53 1.12e-02 GO:0003008 system process
6.92 1.90e-02 GO:0018149 peptide cross-linking

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.54 6.53e-05 GO:0005576 extracellular region
1.21 3.78e-02 GO:0016021 integral to membrane
1.25 3.98e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.41 1.06e-04 GO:0004984 olfactory receptor activity
1.83 1.01e-02 GO:0005509 calcium ion binding
1.69 2.52e-02 GO:0004930 G-protein coupled receptor activity