Motif ID: CREB1.p2

Z-value: 2.151


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2081030680.194.7e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_158314963 2.253 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr7_-_140270749 2.169 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr18_+_2561509 1.972 NM_006101
NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr7_-_158314945 1.954 ESYT2
extended synaptotagmin-like protein 2
chr3_+_171558188 1.775 SKIL
SKI-like oncogene
chr3_+_171558215 1.758 SKIL
SKI-like oncogene
chr18_+_2561587 1.663 NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr12_+_97511596 1.586 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr15_+_74416156 1.536 NM_145805
ISL2
ISL LIM homeobox 2
chr12_+_97511585 1.530 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr18_-_2561422 1.513 NM_022840
METTL4
methyltransferase like 4
chr1_+_141560298 1.468


chr12_+_97511594 1.449 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr15_+_74416129 1.444 ISL2
ISL LIM homeobox 2
chr1_-_119484733 1.443 NM_015836
NM_201263
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr16_-_3008162 1.439 NM_021195
CLDN6
claudin 6
chr6_-_15356865 1.418


chr12_+_97511631 1.389 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr8_-_17148637 1.386 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr12_+_97511520 1.378 NM_002635
NM_005888
NM_213611
SLC25A3


solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3


chr16_-_87300233 1.345 NM_001171815
RNF166
ring finger protein 166
chr1_-_15723279 1.343 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr1_+_110328955 1.342 AHCYL1
adenosylhomocysteinase-like 1
chr12_+_97511569 1.341 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr9_+_132990834 1.309 NUP214
nucleoporin 214kDa
chr4_+_153676857 1.294 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr12_+_97511805 1.286 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr5_-_43349338 1.262 NM_001098272
NM_002130
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr6_+_35335278 1.261 ZNF76
zinc finger protein 76
chr5_-_43349249 1.259 HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr12_+_97511601 1.239 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr16_-_87300308 1.235 NM_178841
RNF166
ring finger protein 166
chr1_+_40399618 1.225 NM_012421
RLF
rearranged L-myc fusion
chr9_+_132990760 1.221 NM_005085
NUP214
nucleoporin 214kDa
chr7_-_44992729 1.216 C7orf40
chromosome 7 open reading frame 40
chr1_-_184611012 1.200 NM_003292
TPR
translocated promoter region (to activated MET oncogene)
chr22_+_18485145 1.181 RANBP1
RAN binding protein 1
chr1_+_169721260 1.176 NM_015172
PRRC2C
proline-rich coiled-coil 2C
chr4_+_113777568 1.175 NM_016648
LARP7
La ribonucleoprotein domain family, member 7
chr1_-_15723305 1.171 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr12_+_110764164 1.170 MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
chr11_+_18372687 1.168 LDHA
lactate dehydrogenase A
chr1_+_40399642 1.151 RLF
rearranged L-myc fusion
chr22_+_18485057 1.151 RANBP1
RAN binding protein 1
chr4_-_113777569 1.141 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr7_-_26206891 1.138 NM_002137
NM_031243
HNRNPA2B1

heterogeneous nuclear ribonucleoprotein A2/B1

chr12_+_46133 1.133 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr16_+_87300385 1.129 NM_001012759
NM_001012762
CTU2

cytosolic thiouridylase subunit 2 homolog (S. pombe)

chr11_+_18372682 1.128 LDHA
lactate dehydrogenase A
chr11_+_18372708 1.128 LDHA
lactate dehydrogenase A
chr8_+_17148755 1.125 NM_001145152
NM_152415
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr1_+_36462625 1.113 THRAP3
thyroid hormone receptor associated protein 3
chr13_+_113287048 1.110 NM_007111
TFDP1
transcription factor Dp-1
chr19_-_54618410 1.108 NM_178449
PTH2
parathyroid hormone 2
chr6_+_35335456 1.099 NM_003427
ZNF76
zinc finger protein 76
chr5_-_149809457 1.099 NM_001025070
NM_001025071
NM_005617
RPS14


ribosomal protein S14


chr7_-_106991572 1.094 COG5
component of oligomeric golgi complex 5
chr1_+_119484529 1.076


chr10_+_85889164 1.074 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr6_+_35335212 1.071 ZNF76
zinc finger protein 76
chr22_+_18485076 1.068 RANBP1
RAN binding protein 1
chr7_-_26206889 1.065 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr3_+_52694975 1.049 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr19_-_18253259 1.047


chr6_-_49712483 1.047 NM_000324
RHAG
Rh-associated glycoprotein
chr11_+_18372689 1.043 LDHA
lactate dehydrogenase A
chr15_-_53487748 1.040 NM_004748
NM_020739
CCPG1

cell cycle progression 1

chr2_-_128285136 1.035 WDR33
WD repeat domain 33
chr2_-_87906400 1.032 NM_001078170
RGPD2
RANBP2-like and GRIP domain containing 2
chr3_-_52694554 1.028 NM_018313
PBRM1
polybromo 1
chr3_-_158360576 1.018 CCNL1
cyclin L1
chr4_-_8493327 1.017 NM_001101667
NM_003501
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr12_+_110764427 1.017 MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
chr3_+_171558143 1.005 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr2_+_170149348 0.999 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr11_+_18372493 0.993 NM_001135239
NM_001165415
NM_001165416
NM_005566
LDHA



lactate dehydrogenase A



chr1_-_1812292 0.989 GNB1
CDK11B
guanine nucleotide binding protein (G protein), beta polypeptide 1
cyclin-dependent kinase 11B
chr22_+_18485095 0.986 RANBP1
RAN binding protein 1
chr7_+_106991638 0.986 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr16_+_665680 0.978 RHBDL1
rhomboid, veinlet-like 1 (Drosophila)
chr19_-_18253413 0.972 NM_005354
JUND
jun D proto-oncogene
chr4_+_8493396 0.966 NM_152544
METTL19
methyltransferase like 19
chr19_+_44524936 0.965 SAMD4B
sterile alpha motif domain containing 4B
chr9_-_124066838 0.964 RBM18
RNA binding motif protein 18
chr18_+_52965290 0.951 BOD1P
biorientation of chromosomes in cell division 1 pseudogene
chr5_-_149809424 0.946 RPS14
ribosomal protein S14
chr1_+_51474558 0.935 RNF11
ring finger protein 11
chr2_+_170149092 0.920 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr19_-_18253436 0.915 JUND
jun D proto-oncogene
chr4_-_103967389 0.913 NM_181892
UBE2D3
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr2_-_128285214 0.910 NM_001006622
NM_001006623
NM_018383
WDR33


WD repeat domain 33


chr22_-_18484695 0.898 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr3_+_10043139 0.897 FANCD2
Fanconi anemia, complementation group D2
chr6_+_135860631 0.896 NCRNA00271
non-protein coding RNA 271
chr1_-_1274618 0.891 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr16_+_18986417 0.890 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr1_-_184611424 0.888 TPR
translocated promoter region (to activated MET oncogene)
chr4_-_113777470 0.887 C4orf21
chromosome 4 open reading frame 21
chr1_+_110328830 0.887 NM_006621
AHCYL1
adenosylhomocysteinase-like 1
chr11_+_67984758 0.884 NM_001164160
NM_001164161
NM_001164162
NM_001164163
NM_001164164
NM_018312
PPP6R3





protein phosphatase 6, regulatory subunit 3





chr4_+_75529716 0.884 NM_001657
AREG
amphiregulin
chr3_+_142939725 0.881 NM_014245
NM_183237
RNF7

ring finger protein 7

chr1_+_31542413 0.879 NM_016505
ZCCHC17
zinc finger, CCHC domain containing 17
chr6_+_15357013 0.877 JARID2
jumonji, AT rich interactive domain 2
chr1_-_166171838 0.875 NM_015415
BRP44
brain protein 44
chr7_-_137337354 0.875 NM_194071
CREB3L2
cAMP responsive element binding protein 3-like 2
chr18_-_31901519 0.873 RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr20_-_60151835 0.871 NM_002792
PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
chr7_-_137337318 0.866 CREB3L2
cAMP responsive element binding protein 3-like 2
chr6_-_31779068 0.860 ABHD16A
abhydrolase domain containing 16A
chr22_-_17512174 0.859 NM_022719
DGCR14
DiGeorge syndrome critical region gene 14
chr22_-_17512097 0.858 DGCR14
DiGeorge syndrome critical region gene 14
chr7_-_129379947 0.850 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chrX_-_102828238 0.849 NM_001142418
NM_001142423
NM_001142424
NM_001142425
NM_001142426
NM_001142429
NM_001142430
NM_012286
MORF4L2







mortality factor 4 like 2







chr7_-_137337352 0.844 CREB3L2
cAMP responsive element binding protein 3-like 2
chr22_-_18484744 0.843 NM_022727
NM_182984
TRMT2A

TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)

chr1_+_110328941 0.843 AHCYL1
adenosylhomocysteinase-like 1
chr7_-_106991941 0.842 NM_001161520
NM_006348
NM_181733
COG5


component of oligomeric golgi complex 5


chr1_-_243092581 0.840 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr1_+_36462583 0.838 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr1_-_154665807 0.836 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr6_-_31779033 0.834 ABHD16A
abhydrolase domain containing 16A
chr2_+_108637916 0.834 LIMS1
LIMS3
LIM and senescent cell antigen-like domains 1
LIM and senescent cell antigen-like domains 3
chr11_-_28086263 0.831 KIF18A
kinesin family member 18A
chr9_-_124066901 0.828 NM_033117
RBM18
RNA binding motif protein 18
chr12_-_56111054 0.825 R3HDM2
R3H domain containing 2
chr1_-_1812336 0.825 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr5_-_133589450 0.824 PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chr4_+_144654005 0.823 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr7_+_38184375 0.821 STARD3NL
STARD3 N-terminal like
chr8_+_38973588 0.821 NM_003816
ADAM9
ADAM metallopeptidase domain 9
chr3_-_25680723 0.820 NM_001068
TOP2B
topoisomerase (DNA) II beta 180kDa
chr1_+_51474583 0.819 RNF11
ring finger protein 11
chr11_-_28086277 0.817 NM_031217
KIF18A
kinesin family member 18A
chr1_+_87567164 0.814 LMO4
LIM domain only 4
chr9_-_126743051 0.812 GOLGA1
golgin A1
chr16_+_79598016 0.812 CENPN
centromere protein N
chr1_+_51474531 0.809 NM_014372
RNF11
ring finger protein 11
chr9_+_124066973 0.809 MRRF
mitochondrial ribosome recycling factor
chr22_+_18485068 0.807 RANBP1
RAN binding protein 1
chr6_-_31779082 0.806 ABHD16A
abhydrolase domain containing 16A
chr9_+_124066702 0.805 NM_001173512
NM_138777
MRRF

mitochondrial ribosome recycling factor

chr5_+_44844724 0.800 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr2_+_86994416 0.799 NM_001078170
RGPD2
RANBP2-like and GRIP domain containing 2
chr3_+_11288975 0.794 NM_001136031
NM_001144912
NM_006395
ATG7


ATG7 autophagy related 7 homolog (S. cerevisiae)


chr6_-_74287506 0.794 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr1_+_51474502 0.793 RNF11
ring finger protein 11
chr11_+_69794487 0.789 PPFIA1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
chr7_+_38184393 0.789 STARD3NL
STARD3 N-terminal like
chr10_+_70385889 0.784 NM_004728
DDX21
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
chr6_-_31779099 0.782 NM_021160
ABHD16A
abhydrolase domain containing 16A
chr1_+_226741665 0.778 NM_001010858
RNF187
ring finger protein 187
chr6_-_135860479 0.776 AHI1
Abelson helper integration site 1
chr15_+_70553719 0.776 NM_005744
ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr1_-_39877928 0.775 NM_014571
HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr21_+_43903803 0.773 NM_015056
RRP1B
ribosomal RNA processing 1 homolog B (S. cerevisiae)
chr1_+_31542434 0.772 ZCCHC17
zinc finger, CCHC domain containing 17
chr9_-_122645006 0.769 NM_005047
PSMD5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
chr3_+_10043097 0.769 NM_001018115
NM_033084
FANCD2

Fanconi anemia, complementation group D2

chr19_+_54067450 0.766 NM_014330
PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr3_-_25681394 0.765 TOP2B
topoisomerase (DNA) II beta 180kDa
chr19_+_54067489 0.762 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr1_+_87567136 0.759 LMO4
LIM domain only 4
chr18_-_31901334 0.759 NM_018170
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr6_-_135860561 0.758 NM_001134830
NM_001134831
NM_001134832
NM_017651
AHI1



Abelson helper integration site 1



chr11_-_118740069 0.756 NM_171997
USP2
ubiquitin specific peptidase 2
chr1_-_1812361 0.756 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr1_-_172060077 0.750 CENPL
centromere protein L
chr3_+_10043123 0.747 FANCD2
Fanconi anemia, complementation group D2
chr4_+_144654526 0.746


chr16_+_18986459 0.738 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_+_43303005 0.738 NM_001100594
NM_017719
SNRK

SNF related kinase

chr1_-_1812418 0.736 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr22_-_18484428 0.734 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr18_-_31901517 0.734 RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr15_+_70553743 0.733 ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr19_+_44524939 0.733 NM_018028
SAMD4B
sterile alpha motif domain containing 4B
chr3_+_5204403 0.731 EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr1_-_43005312 0.731 NM_001146289
NM_022356
LEPRE1

leucine proline-enriched proteoglycan (leprecan) 1

chr1_+_110328850 0.730 AHCYL1
adenosylhomocysteinase-like 1
chr1_-_201194033 0.728 ADIPOR1
adiponectin receptor 1
chr9_+_122645164 0.728 LOC253039
hypothetical LOC253039
chr3_+_142939800 0.728 RNF7
ring finger protein 7
chr7_-_19715127 0.728 NM_001002926
TWISTNB
TWIST neighbor
chr9_+_133154896 0.726 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr3_+_184898234 0.722 NM_018023
YEATS2
YEATS domain containing 2
chr9_-_126743115 0.722 NM_002077
GOLGA1
golgin A1
chr3_+_10003579 0.721 LOC442075
hypothetical LOC442075
chr3_+_12573513 0.720 NM_014160
MKRN2
makorin ring finger protein 2
chr22_-_27526452 0.720 XBP1
X-box binding protein 1
chr19_+_13124889 0.714 IER2
immediate early response 2
chr9_+_130684189 0.710 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr1_+_170768635 0.706 NM_014283
C1orf9
chromosome 1 open reading frame 9
chr3_+_44992733 0.706 NM_015004
EXOSC7
exosome component 7
chr5_-_133589644 0.700 PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chr4_+_55956877 0.694 TMEM165
transmembrane protein 165
chr4_-_110574363 0.692 1/2-SBSRNA4
lncRNA_BC009800
chr1_-_1812376 0.691 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chrX_-_128805400 0.691 NM_016032
ZDHHC9
zinc finger, DHHC-type containing 9
chr11_-_118757477 0.690 USP2
ubiquitin specific peptidase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.53 5.43e-22 GO:0044260 cellular macromolecule metabolic process
1.37 3.15e-18 GO:0044237 cellular metabolic process
1.65 2.16e-17 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 3.40e-17 GO:0043170 macromolecule metabolic process
1.74 7.71e-17 GO:0090304 nucleic acid metabolic process
2.53 1.13e-16 GO:0006396 RNA processing
1.34 7.01e-16 GO:0044238 primary metabolic process
1.81 4.44e-15 GO:0016070 RNA metabolic process
1.53 3.27e-14 GO:0006807 nitrogen compound metabolic process
1.54 3.75e-14 GO:0034641 cellular nitrogen compound metabolic process
1.76 4.64e-14 GO:0010467 gene expression
1.29 7.39e-14 GO:0008152 metabolic process
2.28 2.30e-09 GO:0016071 mRNA metabolic process
3.84 4.48e-09 GO:0006403 RNA localization
2.51 4.59e-09 GO:0006397 mRNA processing
3.86 8.10e-09 GO:0050657 nucleic acid transport
3.86 8.10e-09 GO:0050658 RNA transport
3.86 8.10e-09 GO:0051236 establishment of RNA localization
3.97 1.53e-08 GO:0051028 mRNA transport
2.60 1.01e-07 GO:0008380 RNA splicing
3.42 1.66e-07 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.14 3.20e-07 GO:0044265 cellular macromolecule catabolic process
1.89 6.43e-07 GO:0046907 intracellular transport
1.57 1.70e-06 GO:0006996 organelle organization
1.44 2.44e-06 GO:0044267 cellular protein metabolic process
1.68 4.39e-06 GO:0044248 cellular catabolic process
1.82 6.69e-06 GO:0022402 cell cycle process
1.94 1.24e-05 GO:0009057 macromolecule catabolic process
1.70 1.39e-05 GO:0007049 cell cycle
2.72 1.88e-05 GO:0000375 RNA splicing, via transesterification reactions
1.60 2.19e-05 GO:0033036 macromolecule localization
1.86 2.55e-05 GO:0022403 cell cycle phase
1.12 2.71e-05 GO:0009987 cellular process
2.72 2.89e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.72 2.89e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
1.75 3.31e-05 GO:0045184 establishment of protein localization
1.51 3.92e-05 GO:0009059 macromolecule biosynthetic process
1.51 4.75e-05 GO:0034645 cellular macromolecule biosynthetic process
1.75 5.02e-05 GO:0015031 protein transport
1.92 6.31e-05 GO:0000278 mitotic cell cycle
2.27 6.68e-05 GO:0043632 modification-dependent macromolecule catabolic process
1.32 8.73e-05 GO:0071840 cellular component organization or biogenesis
1.37 9.97e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.63 1.07e-04 GO:0051649 establishment of localization in cell
2.22 1.29e-04 GO:0051603 proteolysis involved in cellular protein catabolic process
2.24 1.40e-04 GO:0019941 modification-dependent protein catabolic process
2.24 1.90e-04 GO:0006511 ubiquitin-dependent protein catabolic process
2.18 2.44e-04 GO:0044257 cellular protein catabolic process
2.00 4.26e-04 GO:0000279 M phase
1.37 6.15e-04 GO:0044249 cellular biosynthetic process
1.54 6.64e-04 GO:0051641 cellular localization
1.50 7.82e-04 GO:0009056 catabolic process
2.27 8.28e-04 GO:0034660 ncRNA metabolic process
2.08 8.85e-04 GO:0030163 protein catabolic process
1.35 1.56e-03 GO:0009058 biosynthetic process
1.78 1.57e-03 GO:0051276 chromosome organization
1.29 2.28e-03 GO:0016043 cellular component organization
1.31 2.70e-03 GO:0019538 protein metabolic process
2.13 2.72e-03 GO:0000087 M phase of mitotic cell cycle
1.56 2.79e-03 GO:0008104 protein localization
3.39 4.18e-03 GO:0031123 RNA 3'-end processing
1.33 4.76e-03 GO:0071842 cellular component organization at cellular level
3.61 5.67e-03 GO:0031124 mRNA 3'-end processing
2.09 7.32e-03 GO:0000280 nuclear division
2.09 7.32e-03 GO:0007067 mitosis
1.90 8.66e-03 GO:0016032 viral reproduction
3.45 1.14e-02 GO:0006405 RNA export from nucleus
1.98 1.55e-02 GO:0070647 protein modification by small protein conjugation or removal
2.03 1.70e-02 GO:0048285 organelle fission
3.10 1.74e-02 GO:0051168 nuclear export
1.92 1.77e-02 GO:0034622 cellular macromolecular complex assembly
1.77 2.45e-02 GO:0034621 cellular macromolecular complex subunit organization
2.28 3.05e-02 GO:0034470 ncRNA processing
2.54 3.21e-02 GO:0048193 Golgi vesicle transport
3.40 4.83e-02 GO:0006406 mRNA export from nucleus
1.76 4.85e-02 GO:0006325 chromatin organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.35 4.86e-34 GO:0043231 intracellular membrane-bounded organelle
1.34 7.97e-34 GO:0043227 membrane-bounded organelle
1.24 5.58e-33 GO:0044424 intracellular part
1.23 1.56e-31 GO:0005622 intracellular
1.28 2.85e-28 GO:0043229 intracellular organelle
1.28 6.33e-28 GO:0043226 organelle
1.90 1.59e-26 GO:0044428 nuclear part
1.45 2.34e-24 GO:0044446 intracellular organelle part
1.95 6.28e-24 GO:0031981 nuclear lumen
1.44 9.32e-24 GO:0044422 organelle part
1.44 9.66e-23 GO:0005634 nucleus
1.80 4.66e-22 GO:0070013 intracellular organelle lumen
1.77 1.08e-20 GO:0043233 organelle lumen
1.75 2.99e-20 GO:0031974 membrane-enclosed lumen
1.25 1.82e-15 GO:0005737 cytoplasm
1.92 1.88e-15 GO:0005654 nucleoplasm
1.43 2.01e-11 GO:0032991 macromolecular complex
2.32 1.51e-10 GO:0005730 nucleolus
1.28 3.27e-10 GO:0044444 cytoplasmic part
1.52 2.51e-08 GO:0005829 cytosol
2.05 8.21e-07 GO:0030529 ribonucleoprotein complex
1.35 1.15e-05 GO:0043234 protein complex
1.36 2.71e-05 GO:0043228 non-membrane-bounded organelle
1.36 2.71e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.74 7.03e-05 GO:0044451 nucleoplasm part
1.80 4.05e-04 GO:0005694 chromosome
2.31 4.34e-04 GO:0016604 nuclear body
2.72 6.82e-04 GO:0005681 spliceosomal complex
2.62 9.34e-04 GO:0000775 chromosome, centromeric region
1.05 4.37e-03 GO:0044464 cell part
1.05 4.49e-03 GO:0005623 cell
3.05 7.08e-03 GO:0071013 catalytic step 2 spliceosome
1.32 1.06e-02 GO:0031090 organelle membrane
2.52 1.39e-02 GO:0016607 nuclear speck
1.72 1.72e-02 GO:0044427 chromosomal part
1.46 3.33e-02 GO:0005794 Golgi apparatus
2.30 4.63e-02 GO:0000793 condensed chromosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.27 7.59e-14 GO:0005515 protein binding
2.14 1.05e-13 GO:0003723 RNA binding
1.42 1.07e-09 GO:0003676 nucleic acid binding
1.12 1.03e-07 GO:0005488 binding
1.46 2.30e-07 GO:0000166 nucleotide binding
1.42 2.61e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.46 5.03e-04 GO:0005524 ATP binding
1.39 7.43e-04 GO:0017076 purine nucleotide binding
1.39 7.86e-04 GO:0032553 ribonucleotide binding
1.39 7.86e-04 GO:0032555 purine ribonucleotide binding
1.44 1.09e-03 GO:0030554 adenyl nucleotide binding
1.43 1.24e-03 GO:0032559 adenyl ribonucleotide binding
1.85 1.27e-03 GO:0016874 ligase activity
1.20 1.49e-03 GO:0003824 catalytic activity
2.02 3.45e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.56 1.17e-02 GO:0016462 pyrophosphatase activity
1.56 1.36e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.55 1.57e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.99 1.65e-02 GO:0016881 acid-amino acid ligase activity
1.55 2.60e-02 GO:0017111 nucleoside-triphosphatase activity
2.04 2.63e-02 GO:0019787 small conjugating protein ligase activity
3.23 4.20e-02 GO:0004221 ubiquitin thiolesterase activity