Motif ID: CRX.p2

Z-value: 1.959


Transcription factors associated with CRX.p2:

Gene SymbolEntrez IDGene Name
CRX 1406 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CRXchr19_+_530169100.155.7e-01Click!


Activity profile for motif CRX.p2.

activity profile for motif CRX.p2


Sorted Z-values histogram for motif CRX.p2

Sorted Z-values for motif CRX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CRX.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_559618 3.084


chr1_+_559129 2.966


chr11_+_61473931 2.910 NM_001139443
NM_004183
BEST1

bestrophin 1

chr5_-_134290789 2.466


chr20_-_48686832 2.205 NM_080829
FAM65C
family with sequence similarity 65, member C
chr12_+_56114724 2.055 NM_005538
INHBC
inhibin, beta C
chr11_+_61279436 2.046 NM_013279
C11orf9
chromosome 11 open reading frame 9
chrX_-_24600661 2.030 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr10_-_76538859 2.001 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr22_+_48927610 1.957 NM_001164106
MOV10L1
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr7_-_99115454 1.944 NM_000777
NM_001190484
CYP3A5

cytochrome P450, family 3, subfamily A, polypeptide 5

chr3_-_19950675 1.919 NM_144715
EFHB
EF-hand domain family, member B
chr6_-_149847809 1.907 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr12_+_130004404 1.894 NM_198827
GPR133
G protein-coupled receptor 133
chr12_-_69434330 1.800 PTPRR
protein tyrosine phosphatase, receptor type, R
chr16_+_56567839 1.791 NM_199046
NM_199456
TEPP

testis, prostate and placenta expressed

chr3_+_186529376 1.786 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr11_-_5110383 1.635 NM_001005160
OR52A5
olfactory receptor, family 52, subfamily A, member 5
chr17_+_35718948 1.621 NM_000964
RARA
retinoic acid receptor, alpha
chr9_+_4829763 1.595 RCL1
RNA terminal phosphate cyclase-like 1
chr15_+_21361546 1.520 NM_005664
MKRN3
makorin ring finger protein 3
chr3_+_82117978 1.519


chr6_+_132000134 1.507 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr9_-_99740243 1.502 NM_197978
HEMGN
hemogen
chr1_+_226399026 1.439 NM_001159391
GUK1
guanylate kinase 1
chr16_+_56286212 1.431 NM_032269
CCDC135
coiled-coil domain containing 135
chr11_-_118405288 1.420 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr20_+_42417752 1.407 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr18_+_53865455 1.395 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr15_+_57691272 1.356 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_-_12858956 1.343 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr4_+_17125885 1.336 NM_001079827
CLRN2
clarin 2
chr6_-_49712483 1.267 NM_000324
RHAG
Rh-associated glycoprotein
chrX_-_129347101 1.254 NM_178471
GPR119
G protein-coupled receptor 119
chr2_-_73723001 1.247 NM_003960
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr7_+_111850367 1.243 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr7_+_128367961 1.238 NM_001098627
IRF5
interferon regulatory factor 5
chr11_-_116168316 1.204 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr12_+_108038774 1.202 ACACB
acetyl-CoA carboxylase beta
chr20_+_41621119 1.202 SGK2
serum/glucocorticoid regulated kinase 2
chr1_+_149877955 1.191 SNX27
sorting nexin family member 27
chrX_-_70248022 1.163 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr2_-_73781974 1.156 NM_016347
NAT8B
N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
chr1_+_179164195 1.150


chr16_-_3362283 1.147 NM_001190476
MTRNR2L4
MT-RNR2-like 4
chr12_-_1898063 1.145 NM_172364
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr10_-_82039158 1.141 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr20_+_41621079 1.139 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr8_+_77928372 1.131 ZFHX4
zinc finger homeobox 4
chr17_-_43390108 1.113 NM_024320
PRR15L
proline rich 15-like
chr20_-_43972061 1.106 PLTP
phospholipid transfer protein
chr21_+_44729875 1.097


chr3_+_63928459 1.097 NM_001128149
ATXN7
ataxin 7
chr6_-_24597717 1.086 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr20_-_33793591 1.067 RBM39
RNA binding motif protein 39
chr6_-_25940247 1.063 NM_005074
SLC17A1
solute carrier family 17 (sodium phosphate), member 1
chr3_+_50281582 1.057 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr1_-_109651140 1.054 NM_001010985
MYBPHL
myosin binding protein H-like
chr3_-_195553297 1.048 NM_001080513
CPN2
carboxypeptidase N, polypeptide 2
chr10_-_101831579 1.048 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr1_+_61319976 1.040 NM_001145512
NFIA
nuclear factor I/A
chr1_-_36338436 1.023 NM_005202
COL8A2
collagen, type VIII, alpha 2
chr20_-_33793593 1.015 NM_004902
NM_184234
RBM39

RNA binding motif protein 39

chr14_-_22516271 1.012 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr1_-_153537362 0.998 NM_181871
PKLR
pyruvate kinase, liver and RBC
chr17_+_50333021 0.997 NM_005486
TOM1L1
target of myb1 (chicken)-like 1
chr2_+_3683660 0.993 NM_018436
ALLC
allantoicase
chr7_+_142692165 0.981 NM_153345
TMEM139
transmembrane protein 139
chr19_-_60360768 0.962 NM_000363
TNNI3
troponin I type 3 (cardiac)
chr1_+_205344200 0.961 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr1_+_152560179 0.961 NM_080429
AQP10
aquaporin 10
chr6_-_149847718 0.949 ZC3H12D
zinc finger CCCH-type containing 12D
chr10_+_5396975 0.945 NM_053049
UCN3
urocortin 3 (stresscopin)
chr6_-_31953425 0.936 NM_001178045
SLC44A4
solute carrier family 44, member 4
chr12_+_77963563 0.935 NM_001135806
SYT1
synaptotagmin I
chrX_-_135783496 0.920


chr1_-_93030538 0.916 NM_005665
EVI5
ecotropic viral integration site 5
chr6_+_105511615 0.907 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr1_-_53380709 0.901 NM_006671
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr6_-_2696152 0.900 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chr20_-_33793507 0.894 RBM39
RNA binding motif protein 39
chr5_+_140454382 0.889 NM_018936
PCDHB2
protocadherin beta 2
chr11_-_117589283 0.881 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr11_+_62813947 0.876 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr19_-_56585603 0.874 NM_001193623
LOC147646
hypothetical protein LOC147646
chr17_+_38306339 0.859 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr2_-_88208650 0.857 NM_001443
FABP1
fatty acid binding protein 1, liver
chr1_-_26266571 0.852 NM_032588
TRIM63
tripartite motif containing 63
chr2_-_75650355 0.847 NM_032181
FAM176A
family with sequence similarity 176, member A
chr2_+_108360798 0.845 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr12_-_55730125 0.843 NM_005379
MYO1A
myosin IA
chr10_+_4995685 0.841 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr19_-_5789740 0.839 FUT6
fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr16_-_54424517 0.829 NM_001025194
NM_001025195
NM_001266
CES1


carboxylesterase 1


chr10_-_74384485 0.822 NM_032562
PLA2G12B
phospholipase A2, group XIIB
chr21_+_39745649 0.819 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr5_-_34020445 0.817 NM_001012509
NM_016180
SLC45A2

solute carrier family 45, member 2

chr1_+_116744992 0.814 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr19_-_53914768 0.806 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr17_-_36346240 0.803 KRT23
keratin 23 (histone deacetylase inducible)
chr18_-_13905534 0.799 NM_000529
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr6_-_66473790 0.797 NM_001142800
NM_001142801
EYS

eyes shut homolog (Drosophila)

chr2_+_128009782 0.796 NM_001080527
MYO7B
myosin VIIB
chr14_+_87560646 0.794 LOC283587
hypothetical protein LOC283587
chr3_-_57209319 0.794 NM_003865
HESX1
HESX homeobox 1
chr2_-_190635566 0.787 NM_005259
MSTN
myostatin
chr7_-_142369519 0.782 KEL
Kell blood group, metallo-endopeptidase
chr6_+_7052798 0.780 NM_001168344
RREB1
ras responsive element binding protein 1
chr21_+_37377116 0.776 NM_003316
TTC3
tetratricopeptide repeat domain 3
chr12_-_52975823 0.770 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr9_-_14076901 0.769 NFIB
nuclear factor I/B
chr17_-_39500512 0.765 NM_152344
LSM12
LSM12 homolog (S. cerevisiae)
chr16_-_20246309 0.762 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr4_+_74496575 0.750 ALB
albumin
chr1_-_27871287 0.749 IFI6
interferon, alpha-inducible protein 6
chr11_-_34491878 0.747 NM_001422
ELF5
E74-like factor 5 (ets domain transcription factor)
chr19_+_43616167 0.746 NM_000540
NM_001042723
RYR1

ryanodine receptor 1 (skeletal)

chr22_-_36305883 0.740 NM_006498
LGALS2
lectin, galactoside-binding, soluble, 2
chr17_+_1586034 0.735 WDR81
WD repeat domain 81
chr14_-_23847000 0.732 CIDEB
cell death-inducing DFFA-like effector b
chr2_-_180580024 0.723 NM_020943
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr21_-_38415273 0.709 NM_005867
DSCR4
Down syndrome critical region gene 4
chr14_-_23846993 0.709 CIDEB
cell death-inducing DFFA-like effector b
chr5_+_76181581 0.707 NM_130772
S100Z
S100 calcium binding protein Z
chr8_-_110730183 0.704 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chrX_+_64625339 0.704 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr11_-_85074848 0.702 NM_152723
CCDC89
coiled-coil domain containing 89
chr14_+_20226762 0.701 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr20_-_33793286 0.701 RBM39
RNA binding motif protein 39
chr6_-_11887265 0.698 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr1_+_35507145 0.697 NM_005095
ZMYM4
zinc finger, MYM-type 4
chr3_+_50281309 0.694 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr14_-_22610572 0.688 ACIN1
apoptotic chromatin condensation inducer 1
chr14_-_22610610 0.684 NM_001164816
NM_001164817
ACIN1

apoptotic chromatin condensation inducer 1

chr10_+_70745615 0.680 NM_033496
HK1
hexokinase 1
chr19_-_49725387 0.677 NM_001102597
NM_001102598
NM_001102599
NM_001102600
CEACAM20



carcinoembryonic antigen-related cell adhesion molecule 20



chr9_+_132990760 0.677 NM_005085
NUP214
nucleoporin 214kDa
chr2_+_201806410 0.671 NM_001080124
NM_001228
NM_033355
NM_033358
CASP8



caspase 8, apoptosis-related cysteine peptidase



chr2_+_113601608 0.669 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr7_-_18033970 0.668 NM_175886
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr7_-_122130201 0.664 NM_198085
RNF148
ring finger protein 148
chr16_-_46823682 0.662 NM_033151
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr4_-_184480572 0.658 NM_001185149
CLDN24
claudin 24
chr1_-_172153087 0.656 NM_000488
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr19_-_12802206 0.647 NM_001080997
RTBDN
retbindin
chr3_-_49812257 0.647 NM_001007540
CDHR4
cadherin-related family member 4
chr6_+_47732181 0.641 NM_153839
GPR111
G protein-coupled receptor 111
chrX_-_11194015 0.641 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr4_-_155753249 0.640 FGG
fibrinogen gamma chain
chr6_-_31812251 0.639 CLIC1
chloride intracellular channel 1
chr1_-_180621272 0.638 GLUL
glutamate-ammonia ligase
chr7_+_29486010 0.638 NM_001039936
CHN2
chimerin (chimaerin) 2
chr20_-_43163021 0.633 NM_002251
KCNS1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr1_+_144152864 0.630 TXNIP
thioredoxin interacting protein
chr16_+_29597965 0.629 QPRT
quinolinate phosphoribosyltransferase
chr2_+_211050653 0.626 NM_001122633
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr2_-_200033445 0.624 SATB2
SATB homeobox 2
chr17_-_36528113 0.623 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr3_-_52712639 0.622 NM_152932
GLT8D1
glycosyltransferase 8 domain containing 1
chr1_+_32512298 0.621 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr2_+_113601616 0.620 IL1RN
interleukin 1 receptor antagonist
chr1_-_156923111 0.619 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_-_142369534 0.616 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr18_-_41923571 0.615 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr9_-_33385265 0.611 AQP7
aquaporin 7
chr16_+_29597829 0.610 NM_014298
QPRT
quinolinate phosphoribosyltransferase
chr19_-_4253389 0.609 NM_001169126
NM_144615
TMIGD2

transmembrane and immunoglobulin domain containing 2

chr1_+_31655607 0.599 NM_001199037
SERINC2
serine incorporator 2
chr20_-_48165886 0.598 NM_022442
NM_021988
NM_199144
UBE2V1


ubiquitin-conjugating enzyme E2 variant 1


chr6_-_31812260 0.594 CLIC1
chloride intracellular channel 1
chr9_-_85773899 0.593 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr22_+_23329113 0.590 NM_001032364
NM_005265
GGT1

gamma-glutamyltransferase 1

chr14_-_23847024 0.589 CIDEB
cell death-inducing DFFA-like effector b
chr4_-_155753272 0.581 FGG
fibrinogen gamma chain
chr1_+_205329206 0.580 NM_000716
NM_001017364
NM_001017367
C4BPB


complement component 4 binding protein, beta


chr7_-_150352484 0.580 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr18_+_31488530 0.579 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr20_-_3097070 0.572 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr17_+_53670785 0.571 NM_001160102
NM_006151
LPO

lactoperoxidase

chr5_+_140605100 0.569 PCDHB15
protocadherin beta 15
chr1_+_114323552 0.565 NM_020190
OLFML3
olfactomedin-like 3
chr3_+_185300660 0.564 NM_182589
HTR3E
5-hydroxytryptamine (serotonin) receptor 3, family member E
chr4_+_74496660 0.564 ALB
albumin
chr6_-_31812214 0.563 CLIC1
chloride intracellular channel 1
chr12_+_12115668 0.560 NM_030766
NM_138722
BCL2L14

BCL2-like 14 (apoptosis facilitator)

chr5_-_74568458 0.559 NM_001164443
ANKRD31
ankyrin repeat domain 31
chr11_+_76561471 0.556 MYO7A
myosin VIIA
chr14_-_23846904 0.556 CIDEB
cell death-inducing DFFA-like effector b
chr17_-_54124374 0.553 NM_031272
NM_198393
TEX14

testis expressed 14

chr10_-_5035967 0.553 NM_001135241
AKR1C1
AKR1C2
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr17_+_35484204 0.553 THRA
thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
chrX_+_123307812 0.550 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr16_+_24765052 0.549 NM_052944
SLC5A11
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr19_-_56018815 0.548 NM_002257
KLK1
kallikrein 1
chr6_-_31812297 0.545 NM_001288
CLIC1
chloride intracellular channel 1
chr7_-_128203079 0.544 NM_001708
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr5_-_150264696 0.539 NM_001172831
NM_001172832
NM_052860
ZNF300


zinc finger protein 300


chr8_+_124154079 0.537 NM_001145088
NM_145647
WDR67

WD repeat domain 67

chr12_-_52975777 0.536 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr5_-_39255335 0.536 NM_001465
NM_199335
FYB

FYN binding protein


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.53 2.52e-02 GO:0007600 sensory perception

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.00 3.29e-02 GO:0045111 intermediate filament cytoskeleton

Nothing significant found in function category.