Motif ID: CTCF.p2

Z-value: 3.031


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CTCFchr16_+_661538100.784.2e-04Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_21231421 6.826 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr1_-_200396354 4.833 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr19_-_6432765 4.577 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr1_+_246167115 4.316 NM_175911
OR2L13
olfactory receptor, family 2, subfamily L, member 13
chr7_-_38341697 3.451 TRGV7
T cell receptor gamma variable 7 pseudogene
chr1_-_36338436 3.300 NM_005202
COL8A2
collagen, type VIII, alpha 2
chr21_+_41663853 3.114 MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr17_+_16259636 2.971 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr22_+_20880159 2.936 IGLV6-57
immunoglobulin lambda variable 6-57
chr17_+_16259573 2.925 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr1_+_149395728 2.871 NM_024575
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr22_+_21393107 2.844 IGLJ3
immunoglobulin lambda joining 3
chr7_-_38355949 2.796


chr3_-_129694717 2.773 NM_032638
GATA2
GATA binding protein 2
chr7_-_38356100 2.742 TRGV5
T cell receptor gamma variable 5
chr1_-_32054164 2.730 NM_144569
SPOCD1
SPOC domain containing 1
chr18_+_586997 2.669 NM_014410
CLUL1
clusterin-like 1 (retinal)
chr19_-_11425568 2.588 ELAVL3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr3_-_198240969 2.565 MFI2
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr22_+_20880112 2.532


chr11_+_61276576 2.503 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr17_-_34014390 2.439 SRCIN1
SRC kinase signaling inhibitor 1
chr19_+_12810258 2.432 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr3_-_198241079 2.430 NM_033316
NM_005929
MFI2

antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5

chr3_-_48573556 2.370 PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr9_+_130005429 2.353 NM_001005336
NM_004408
DNM1

dynamin 1

chr17_-_59312892 2.331 NM_002059
NM_022556
NM_022557
NM_022558
GH2



growth hormone 2



chr9_-_111123017 2.328 EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr9_+_130005487 2.302 DNM1
dynamin 1
chr21_-_37284351 2.297 NM_000411
HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr9_+_138858687 2.284 NM_001080482
C9orf172
chromosome 9 open reading frame 172
chr22_+_21742727 2.255 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr17_-_69869552 2.252 NM_001080466
BTBD17
BTB (POZ) domain containing 17
chr14_+_30413393 2.251 NM_001135058
NM_004086
COCH

coagulation factor C homolog, cochlin (Limulus polyphemus)

chr22_+_21742364 2.236 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr11_-_64268126 2.187 NM_001098671
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chrX_-_134798808 2.177 NM_001017438
CT45A3
CT45A4
CT45A5
CT45A6
CT45A1
cancer/testis antigen family 45, member A3
cancer/testis antigen family 45, member A4
cancer/testis antigen family 45, member A5
cancer/testis antigen family 45, member A6
cancer/testis antigen family 45, member A1
chr19_+_54226941 2.162 NM_033378
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr22_+_18085891 2.150 SEPT5
septin 5
chr20_+_29492071 2.140 NM_153324
DEFB123
defensin, beta 123
chr2_+_171493870 2.137 NM_015530
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr22_+_18085990 2.120 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr19_+_10388448 2.111 PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_221966835 2.110 CAPN2
calpain 2, (m/II) large subunit
chr2_+_218929822 2.107 NM_198559
C2orf62
chromosome 2 open reading frame 62
chr20_+_48240705 2.091 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr19_-_15451203 2.081 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr9_+_130005489 2.076 DNM1
dynamin 1
chr16_+_2807228 2.033 PRSS21
protease, serine, 21 (testisin)
chr16_-_2330594 2.029 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr16_+_65870891 2.024 NM_001129729
NM_001129731
PLEKHG4

pleckstrin homology domain containing, family G (with RhoGef domain) member 4

chr9_-_139262009 2.018 NM_001001710
FAM166A
family with sequence similarity 166, member A
chr18_-_17434811 2.017 ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr1_-_200396328 2.016 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr19_-_53841064 2.015 NM_001217
CA11
carbonic anhydrase XI
chr17_+_71508581 2.000 NM_001258
CDK3
cyclin-dependent kinase 3
chr1_+_221966849 1.996 CAPN2
calpain 2, (m/II) large subunit
chr7_+_128367961 1.991 NM_001098627
IRF5
interferon regulatory factor 5
chr22_-_20637188 1.990 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr1_+_93070186 1.984 RPL5
ribosomal protein L5
chr17_-_40858775 1.968 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr22_-_20637212 1.965 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr1_+_153232685 1.944 NM_018655
LENEP
lens epithelial protein
chr16_+_73590419 1.915 ZNRF1
zinc and ring finger 1
chr1_+_93070120 1.896 NM_000969
RPL5
ribosomal protein L5
chr7_+_148475373 1.883 NM_170686
ZNF398
zinc finger protein 398
chr16_-_2330712 1.860 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr12_-_112057650 1.853 NM_001193521
RASAL1
RAS protein activator like 1 (GAP1 like)
chr1_+_93070202 1.816 RPL5
ribosomal protein L5
chr2_-_39310176 1.809 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr2_+_228045053 1.786 AGFG1
ArfGAP with FG repeats 1
chr19_-_4351470 1.783 NM_003025
SH3GL1
SH3-domain GRB2-like 1
chr17_-_70430839 1.776 NM_173477
USH1G
Usher syndrome 1G (autosomal recessive)
chr17_-_45829863 1.776 LRRC59
leucine rich repeat containing 59
chr19_-_53515143 1.773 NM_144577
CCDC114
coiled-coil domain containing 114
chr17_-_45829869 1.757 LRRC59
leucine rich repeat containing 59
chr10_+_26263163 1.750 MYO3A
myosin IIIA
chr20_+_48240772 1.743 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr6_-_47385605 1.740 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr9_-_111122826 1.740 NM_018424
NM_019114
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr1_+_221966951 1.736 CAPN2
calpain 2, (m/II) large subunit
chr16_+_73590375 1.728 NM_032268
ZNRF1
zinc and ring finger 1
chr3_-_110319598 1.719 NM_014429
MORC1
MORC family CW-type zinc finger 1
chr14_-_23847000 1.714 CIDEB
cell death-inducing DFFA-like effector b
chr20_+_48240867 1.704 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr15_-_38387164 1.703 PLCB2
phospholipase C, beta 2
chr19_-_46551670 1.698 NM_000660
TGFB1
transforming growth factor, beta 1
chr10_+_6284845 1.686 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr3_+_50272648 1.683


chr16_-_23476138 1.667 NM_001083614
EARS2
glutamyl-tRNA synthetase 2, mitochondrial (putative)
chr16_+_73590470 1.650 ZNRF1
zinc and ring finger 1
chr19_-_4351357 1.640 SH3GL1
SH3-domain GRB2-like 1
chr6_-_41114905 1.637 NM_173561
UNC5CL
unc-5 homolog C (C. elegans)-like
chr22_+_21027538 1.636


chr1_+_36121382 1.631 NM_012199
EIF2C1
eukaryotic translation initiation factor 2C, 1
chr19_+_60505205 1.619 BRSK1
BR serine/threonine kinase 1
chr9_-_38059207 1.611 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr1_+_36121400 1.607 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr11_+_915795 1.606 NM_012305
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr6_+_87703742 1.603 NM_000865
HTR1E
5-hydroxytryptamine (serotonin) receptor 1E
chr14_-_106352471 1.602


chr1_+_108765634 1.601 LOC400768
hypothetical LOC400768
chr21_+_44549486 1.598 PFKL
phosphofructokinase, liver
chr2_+_182464713 1.573 NM_001130445
NM_006751
SSFA2

sperm specific antigen 2

chr6_+_35544155 1.572 NM_007104
RPL10A
ribosomal protein L10a
chr6_-_139351084 1.563 NM_001128617
NM_031922
REPS1

RALBP1 associated Eps domain containing 1

chr2_+_27163114 1.561 NM_000221
NM_006488
KHK

ketohexokinase (fructokinase)

chr9_+_139437624 1.558 NM_006647
NOXA1
NADPH oxidase activator 1
chr16_-_2330738 1.555 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr1_-_243093833 1.545 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr17_-_45829909 1.540 NM_018509
LRRC59
leucine rich repeat containing 59
chr14_-_23846993 1.537 CIDEB
cell death-inducing DFFA-like effector b
chr2_-_232103352 1.537 NM_006056
NMUR1
neuromedin U receptor 1
chr12_-_112058403 1.534 NM_001193520
NM_004658
RASAL1

RAS protein activator like 1 (GAP1 like)

chr1_+_110328830 1.532 NM_006621
AHCYL1
adenosylhomocysteinase-like 1
chr19_-_12028126 1.528 NM_001080404
ZNF878
zinc finger protein 878
chr14_-_23847024 1.527 CIDEB
cell death-inducing DFFA-like effector b
chr3_+_5138929 1.526 NM_018184
ARL8B
ADP-ribosylation factor-like 8B
chr6_-_47385599 1.525 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr17_-_38087366 1.516 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr20_-_1395529 1.514 NSFL1C
NSFL1 (p97) cofactor (p47)
chr19_-_54231884 1.505 NM_033377
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr18_-_17434655 1.494 NM_052911
ESCO1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr6_+_35544174 1.491 RPL10A
ribosomal protein L10a
chr19_+_5774817 1.484 NM_004558
NRTN
neurturin
chr18_-_45975163 1.475 NM_001080467
MYO5B
myosin VB
chr19_-_4509471 1.456 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr19_+_60505413 1.436 BRSK1
BR serine/threonine kinase 1
chr19_+_18560494 1.435 NM_001100418
NM_001100419
C19orf60

chromosome 19 open reading frame 60

chr16_+_66236512 1.431 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr16_+_30903963 1.428 NM_001142777
NM_001142778
NM_025193
HSD3B7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chrX_+_148770598 1.423 NM_001166400
NM_001166401
NM_005364
MAGEA8


melanoma antigen family A, 8


chr6_-_47385604 1.418 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr1_+_28935719 1.412 NM_001173128
NM_016258
YTHDF2

YTH domain family, member 2

chr6_+_33467290 1.407 NM_002263
KIFC1
kinesin family member C1
chr6_+_34590624 1.404 PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr6_-_139351032 1.398 REPS1
RALBP1 associated Eps domain containing 1
chr10_+_35455806 1.394 NM_001881
NM_182850
NM_182853
NM_183013
CREM



cAMP responsive element modulator



chr6_-_41781655 1.384 TFEB
transcription factor EB
chr11_+_66790517 1.381 ADRBK1
adrenergic, beta, receptor kinase 1
chr22_-_49311722 1.378 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr17_-_45829677 1.372 LRRC59
leucine rich repeat containing 59
chr7_-_100009205 1.366 NM_001168682
SAP25
sin3A-binding protein 25
chr11_-_64267037 1.358 RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr22_+_21079355 1.343


chr2_+_171494026 1.341 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr19_+_1892157 1.329 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr3_+_5139009 1.326 ARL8B
ADP-ribosylation factor-like 8B
chr16_+_170334 1.322 NM_005331
HBQ1
hemoglobin, theta 1
chr11_+_915874 1.321 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr14_+_104261578 1.312 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr16_-_10183244 1.312 NM_001134408
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr2_+_182464910 1.310 SSFA2
sperm specific antigen 2
chr20_-_32924219 1.305 NM_178026
GGT7
gamma-glutamyltransferase 7
chr6_-_47385470 1.304 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr1_-_6537171 1.293 NM_024654
NOL9
nucleolar protein 9
chr8_+_145568526 1.289 NM_174922
ADCK5
aarF domain containing kinase 5
chr2_+_73864823 1.257 NM_001080474
C2orf78
chromosome 2 open reading frame 78
chr22_+_18388633 1.250 C22orf25
chromosome 22 open reading frame 25
chr2_+_6974922 1.248 NM_014746
RNF144A
ring finger protein 144A
chrX_+_134693879 1.246 NM_001017436
NM_152582
CT45A3
CT45A4
CT45A2
cancer/testis antigen family 45, member A3
cancer/testis antigen family 45, member A4
cancer/testis antigen family 45, member A2
chr1_+_191357680 1.244 NM_024529
CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_-_6537139 1.241 NOL9
nucleolar protein 9
chr3_+_5139028 1.237 ARL8B
ADP-ribosylation factor-like 8B
chr19_+_1892184 1.232 CSNK1G2
casein kinase 1, gamma 2
chr22_-_17512174 1.222 NM_022719
DGCR14
DiGeorge syndrome critical region gene 14
chr19_+_51059357 1.215 NM_004497
FOXA3
forkhead box A3
chr1_-_17638797 1.211 NM_018715
RCC2
regulator of chromosome condensation 2
chr20_+_31783426 1.210 NM_032819
ZNF341
zinc finger protein 341
chrX_+_119268713 1.208


chr9_+_126655516 1.206 NM_001045476
WDR38
WD repeat domain 38
chr22_-_17512097 1.205 DGCR14
DiGeorge syndrome critical region gene 14
chr19_+_59618416 1.205 NM_001005367
NM_020659
TTYH1

tweety homolog 1 (Drosophila)

chr19_-_2002222 1.205 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr20_+_35964962 1.192 VSTM2L
V-set and transmembrane domain containing 2 like
chr7_+_99919485 1.192 NM_173564
C7orf51
chromosome 7 open reading frame 51
chr20_+_35964912 1.190 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr10_+_35455986 1.184 CREM
cAMP responsive element modulator
chr6_+_151228383 1.181 NM_015440
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr11_-_72182291 1.177 NM_006645
STARD10
StAR-related lipid transfer (START) domain containing 10
chr1_+_109090789 1.177 NM_007269
STXBP3
syntaxin binding protein 3
chr1_+_16639753 1.174 NM_001145277
NM_001145278
NM_018090
NECAP2


NECAP endocytosis associated 2


chr19_-_19233370 1.166 HAPLN4
hyaluronan and proteoglycan link protein 4
chr19_-_46551607 1.164 TGFB1
transforming growth factor, beta 1
chr22_-_23665312 1.163 NM_001001663
TMEM211
transmembrane protein 211
chr17_-_31104009 1.157 NM_139285
GAS2L2
growth arrest-specific 2 like 2
chr17_-_8809656 1.150 NM_001142633
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr17_-_23244499 1.149 NM_001076680
C17orf108
chromosome 17 open reading frame 108
chr14_-_106154332 1.144 LOC100126583
IGHG1
hypothetical LOC100126583
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_-_52393364 1.144 NM_004645
COIL
coilin
chr1_+_20081424 1.135 NM_015207
OTUD3
OTU domain containing 3
chr2_-_131966416 1.135 MZT2A
mitotic spindle organizing protein 2A
chr11_-_57275828 1.134 NM_001145101
BTBD18
BTB (POZ) domain containing 18
chr5_-_179568730 1.133 NM_175062
RASGEF1C
RasGEF domain family, member 1C
chr17_+_24394043 1.132 NM_016518
PIPOX
pipecolic acid oxidase
chr19_-_14085979 1.131 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr11_+_63775572 1.126 PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr16_-_65422365 1.125 NM_001018159
NM_001018160
NM_003905
NAE1


NEDD8 activating enzyme E1 subunit 1


chr17_-_24253821 1.120 NM_144683
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr20_+_60311334 1.117 ADRM1
adhesion regulating molecule 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 9.82e-04 GO:0005622 intracellular
1.13 2.75e-03 GO:0044424 intracellular part
1.17 9.72e-03 GO:0005737 cytoplasm
1.22 1.65e-02 GO:0044444 cytoplasmic part
1.43 2.41e-02 GO:0005829 cytosol

Nothing significant found in function category.