• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: EGR1..3.p2

Z-value: 2.105

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_-_152592450	3.413		PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr16_+_29725311	3.361	NM_001042539 NM_002383	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_+_29725597	2.443
chr16_-_53520208	2.340		CRNDE	colorectal neoplasia differentially expressed (non-protein coding)
chr2_+_104838177	2.268	NM_006236	POU3F3	POU class 3 homeobox 3
chr16_+_1143241	2.072	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr19_+_1704661	2.052	NM_001080488	ONECUT3	one cut homeobox 3
chr9_-_122679387	2.020	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr22_+_38183262	1.964	NM_002409	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr7_-_150283794	1.867	NM_172057	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr16_+_88305743	1.845		LOC100128881	hypothetical LOC100128881
chrX_-_152591936	1.748	NM_001135740	PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr6_-_13819622	1.683	NM_005493	RANBP9	RAN binding protein 9
chr1_+_224317062	1.654		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr1_+_224317030	1.636		H3F3A	H3 histone, family 3A
chr6_-_79844618	1.601		PHIP	pleckstrin homology domain interacting protein
chr3_-_24511456	1.585		THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr1_+_224317056	1.577		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr7_+_128257698	1.575	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr22_-_20551937	1.568		MAPK1	mitogen-activated protein kinase 1
chr16_+_29725665	1.525
chr1_+_224317036	1.501	NM_002107	H3F3A	H3 histone, family 3A
chr7_-_151763857	1.491		MLL3	myeloid/lymphoid or mixed-lineage leukemia 3
chr3_-_39170105	1.484	NM_033027	CSRNP1	cysteine-serine-rich nuclear protein 1
chr6_-_79844503	1.478		PHIP	pleckstrin homology domain interacting protein
chr1_+_32992131	1.473
chr17_-_44010543	1.469	NM_024015	HOXB4	homeobox B4
chr14_-_104705753	1.462		JAG2	jagged 2
chr9_-_122679283	1.461		PHF19	PHD finger protein 19
chr7_-_151764004	1.457	NM_170606	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3
chr22_-_20551722	1.457		MAPK1	mitogen-activated protein kinase 1
chr6_-_79844606	1.445		PHIP	pleckstrin homology domain interacting protein
chr14_+_106009489	1.439		NCRNA00221	non-protein coding RNA 221
chr1_+_224317044	1.400		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr19_+_40451720	1.362	NM_003367 NM_207291	USF2	upstream transcription factor 2, c-fos interacting
chrX_-_135161185	1.339	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr14_-_104706159	1.317	NM_002226 NM_145159	JAG2	jagged 2
chr1_-_31154023	1.307	NM_014654	SDC3	syndecan 3
chr1_+_210525885	1.295		PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr19_-_3737382	1.271	NM_139354 NM_139355	MATK	megakaryocyte-associated tyrosine kinase
chr3_-_39170038	1.268		CSRNP1	cysteine-serine-rich nuclear protein 1
chr22_+_18081968	1.266	NM_002688	SEPT5	septin 5
chr6_+_79844267	1.263		PHIP	pleckstrin homology domain interacting protein
chr17_+_77582774	1.259	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr1_+_210525792	1.251		PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr19_+_7834124	1.249		EVI5L	ecotropic viral integration site 5-like
chr9_-_139027435	1.230		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr11_-_63770716	1.228		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_-_187025501	1.225	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr22_+_20101661	1.215	NM_015094	HIC2	hypermethylated in cancer 2
chr9_+_130491668	1.212		SET	SET nuclear oncogene
chr18_+_12397894	1.202	NM_001142405 NM_006553	SLMO1	slowmo homolog 1 (Drosophila)
chr3_-_187025438	1.198		IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr16_+_82559600	1.195	NM_019065	NECAB2	N-terminal EF-hand calcium binding protein 2
chr1_-_51198328	1.193		FAF1	Fas (TNFRSF6) associated factor 1
chr11_+_2422747	1.176	NM_000218	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1
chr10_+_134893766	1.174	NM_003577	UTF1	undifferentiated embryonic cell transcription factor 1
chr1_-_21375939	1.165	NM_001198801 NM_001198802	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr12_-_123023312	1.161		CCDC92	coiled-coil domain containing 92
chr6_-_13819463	1.127		RANBP9	RAN binding protein 9
chrX_-_48699797	1.124	NM_001136157 NM_001136158 NM_017602	OTUD5	OTU domain containing 5
chr1_+_35507145	1.120	NM_005095	ZMYM4	zinc finger, MYM-type 4
chr1_-_51198506	1.111	NM_007051	FAF1	Fas (TNFRSF6) associated factor 1
chr12_+_19484044	1.109		AEBP2	AE binding protein 2
chr19_-_56260135	1.094	NM_015596	KLK13	kallikrein-related peptidase 13
chr7_+_154720547	1.087		INSIG1	insulin induced gene 1
chr21_-_39642935	1.086		HMGN1	high-mobility group nucleosome binding domain 1
chr6_-_85530617	1.085	NM_001080508	TBX18	T-box 18
chr1_-_1812353	1.084	NM_002074	GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1
chr9_+_95253732	1.082	NM_014612	FAM120A	family with sequence similarity 120A
chr14_-_60022487	1.081	NM_174978	C14orf39	chromosome 14 open reading frame 39
chr7_-_140270749	1.081	NM_004333	BRAF	v-raf murine sarcoma viral oncogene homolog B1
chr22_+_18091065	1.077	NM_000407	GP1BB	glycoprotein Ib (platelet), beta polypeptide
chr6_-_84197573	1.060	NM_002395	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr2_+_102602579	1.055	NM_003048	SLC9A2	solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr1_-_54644566	1.032	NM_018070 NM_145716	SSBP3	single stranded DNA binding protein 3
chr14_-_99016917	1.025		SETD3	SET domain containing 3
chr2_+_149119029	1.023	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr5_+_176493233	1.014	NM_022455	NSD1	nuclear receptor binding SET domain protein 1
chr4_-_74343320	1.013	NM_032217 NM_198889	ANKRD17	ankyrin repeat domain 17
chr22_+_38183480	1.012		MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr15_+_65145248	1.011	NM_005902	SMAD3	SMAD family member 3
chr4_+_129951877	1.010		PHF17	PHD finger protein 17
chr14_-_99016866	1.008		SETD3	SET domain containing 3
chr3_+_185515543	1.006	NM_182917	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr17_+_63252704	1.001		BPTF	bromodomain PHD finger transcription factor
chr1_+_65763978	0.998		LEPR	leptin receptor
chr1_+_246087230	0.989		TRIM58	tripartite motif containing 58
chr19_+_1200882	0.987		MIDN	midnolin
chr1_+_65763945	0.987	NM_001198687 NM_001198688 NM_001198689	LEPR	leptin receptor
chr9_-_100510657	0.982	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chr9_+_130491370	0.979		SET	SET nuclear oncogene
chr9_+_130491644	0.971		SET	SET nuclear oncogene
chr1_+_41022066	0.969	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr16_-_695719	0.968	NM_153350	FBXL16	F-box and leucine-rich repeat protein 16
chr22_-_20551953	0.963	NM_002745 NM_138957	MAPK1	mitogen-activated protein kinase 1
chr1_-_38243747	0.958	NM_004468	FHL3	four and a half LIM domains 3
chr11_-_32413486	0.954		WT1	Wilms tumor 1
chr10_+_45189617	0.953	NM_000698	ALOX5	arachidonate 5-lipoxygenase
chr6_+_157141565	0.952		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr1_-_51198417	0.939		FAF1	Fas (TNFRSF6) associated factor 1
chr19_+_40451842	0.932		USF2	upstream transcription factor 2, c-fos interacting
chrX_-_48699702	0.930		OTUD5	OTU domain containing 5
chr1_-_38243716	0.927		FHL3	four and a half LIM domains 3
chr12_+_50586958	0.926		ACVRL1	activin A receptor type II-like 1
chr16_+_86193993	0.923	NM_020655	JPH3	junctophilin 3
chr1_+_32251988	0.918	NM_006559	KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1
chr19_-_15304307	0.915		BRD4	bromodomain containing 4
chr22_-_18384251	0.914	NM_001670	ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome
chr5_-_137117333	0.913		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr19_-_1518875	0.911	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr14_-_68515701	0.910		ACTN1	actinin, alpha 1
chr14_-_99016833	0.908		SETD3	SET domain containing 3
chr16_-_1862162	0.903	NM_001163560	C16orf73	chromosome 16 open reading frame 73
chr2_-_174537354	0.895		SP3	Sp3 transcription factor
chr7_+_116380790	0.894		ST7	suppression of tumorigenicity 7
chr12_-_53071285	0.892	NM_001130967 NM_001130968	ZNF385A	zinc finger protein 385A
chr21_-_39642712	0.891		HMGN1	high-mobility group nucleosome binding domain 1
chr19_-_15304304	0.889		BRD4	bromodomain containing 4
chr1_-_40027097	0.887		BMP8B	bone morphogenetic protein 8b
chr5_+_56147136	0.880		MAP3K1	mitogen-activated protein kinase kinase kinase 1
chr19_+_540849	0.880	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr8_-_102032852	0.878		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr12_-_107649383	0.872		CORO1C	coronin, actin binding protein, 1C
chr14_+_28306633	0.867		FOXG1	forkhead box G1
chr4_-_71924052	0.865	NM_001098477	GRSF1	G-rich RNA sequence binding factor 1
chr19_+_40325993	0.865	NM_022006	FXYD7	FXYD domain containing ion transport regulator 7
chr4_-_74343169	0.862
chr4_-_102487649	0.860	NM_000944 NM_001130691 NM_001130692	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_149698272	0.860		POGZ	pogo transposable element with ZNF domain
chr22_-_18807805	0.859		PI4KAP2 PI4KAP1	phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chrX_+_130019896	0.858	NM_144967	ARHGAP36	Rho GTPase activating protein 36
chr4_+_134292630	0.857		PCDH10	protocadherin 10
chr1_-_21375891	0.857		EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr19_+_40451626	0.856		USF2	upstream transcription factor 2, c-fos interacting
chr6_-_15356865	0.853
chr4_-_25473528	0.851	NM_015187	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr8_+_15442100	0.848	NM_006765 NM_178234	TUSC3	tumor suppressor candidate 3
chr14_-_68515525	0.846		ACTN1	actinin, alpha 1
chrX_+_9392980	0.844	NM_005647	TBL1X	transducin (beta)-like 1X-linked
chr19_-_1814425	0.841		KLF16	Kruppel-like factor 16
chr7_+_116289833	0.839		CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2
chr13_-_107317460	0.836	NM_001080396	FAM155A	family with sequence similarity 155, member A
chr1_-_1812418	0.834		GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1
chr5_+_149526533	0.828	NM_001804	CDX1	caudal type homeobox 1
chr1_-_51198052	0.826		FAF1	Fas (TNFRSF6) associated factor 1
chr19_+_40451807	0.823		USF2	upstream transcription factor 2, c-fos interacting
chr12_+_88626770	0.822		LOC338758	hypothetical LOC338758
chr14_-_99016959	0.822	NM_032233 NM_199123	SETD3	SET domain containing 3
chr3_-_15875932	0.821	NM_015199	ANKRD28	ankyrin repeat domain 28
chr1_+_39229474	0.820	NM_001136275 NM_024595	AKIRIN1	akirin 1
chr19_+_10843244	0.819	NM_199141	CARM1	coactivator-associated arginine methyltransferase 1
chr1_+_6767968	0.818	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr6_+_37245860	0.817	NM_002648	PIM1	pim-1 oncogene
chr7_+_64136078	0.810		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr17_-_44058612	0.809	NM_024017	HOXB9	homeobox B9
chr10_+_35665614	0.809	NM_145012	CCNY	cyclin Y
chr7_+_154720416	0.808	NM_005542 NM_198336 NM_198337	INSIG1	insulin induced gene 1
chr12_-_56526713	0.805		CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chrX_+_153339814	0.803	NM_017514	PLXNA3	plexin A3
chr1_+_6596331	0.801	NM_153812	PHF13	PHD finger protein 13
chr19_+_56506907	0.795	NM_001101372	IGLON5	IgLON family member 5
chr20_-_48980858	0.794	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr3_+_171558143	0.793	NM_001145098 NM_005414	SKIL	SKI-like oncogene
chr14_-_64416307	0.792		SPTB	spectrin, beta, erythrocytic
chr3_+_171558188	0.786		SKIL	SKI-like oncogene
chr5_+_56147109	0.785		MAP3K1	mitogen-activated protein kinase kinase kinase 1
chr2_-_100305626	0.784	NM_198461	LONRF2	LON peptidase N-terminal domain and ring finger 2
chr12_-_56526739	0.781		CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr2_+_181553783	0.779		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chrX_-_48700032	0.779		OTUD5	OTU domain containing 5
chr9_+_130491340	0.778		SET	SET nuclear oncogene
chr21_-_39642808	0.776		HMGN1	high-mobility group nucleosome binding domain 1
chr1_-_51198383	0.775		FAF1	Fas (TNFRSF6) associated factor 1
chr16_-_1862080	0.773	NM_152764	C16orf73	chromosome 16 open reading frame 73
chr20_-_61600834	0.771	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr1_+_210525490	0.769	NM_006243	PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr15_-_99847109	0.767		PCSK6	proprotein convertase subtilisin/kexin type 6
chr2_+_181553333	0.765	NM_182678 NM_006357	UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr22_+_17800018	0.764	NM_003776	MRPL40	mitochondrial ribosomal protein L40
chr1_+_35507197	0.761		ZMYM4	zinc finger, MYM-type 4
chr7_-_156125876	0.761		C7orf13	chromosome 7 open reading frame 13
chr17_-_39652449	0.760	NM_001076684	UBTF	upstream binding transcription factor, RNA polymerase I
chr1_+_177261627	0.759		FAM20B	family with sequence similarity 20, member B
chr5_+_176493488	0.758		NSD1	nuclear receptor binding SET domain protein 1
chr3_-_33456881	0.757	NM_001128161	UBP1	upstream binding protein 1 (LBP-1a)
chr11_-_64302440	0.757		SF1	splicing factor 1
chr8_-_8213270	0.756		SGK223	homolog of rat pragma of Rnd2
chr11_-_63770840	0.755		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_-_25680723	0.754	NM_001068	TOP2B	topoisomerase (DNA) II beta 180kDa
chr6_+_34312906	0.754		HMGA1	high mobility group AT-hook 1
chrX_-_47364173	0.753	NM_006950 NM_133499	SYN1	synapsin I
chr1_+_69806617	0.752		LRRC7	leucine rich repeat containing 7
chr1_-_1812389	0.750		GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1
chr1_+_69806543	0.746
chr1_-_149214063	0.746	NM_022075 NM_181746	LASS2	LAG1 homolog, ceramide synthase 2
chr1_-_153799186	0.744		ASH1L	ash1 (absent, small, or homeotic)-like (Drosophila)
chr19_-_3737279	0.741		MATK	megakaryocyte-associated tyrosine kinase
chr14_-_68515727	0.739		ACTN1	actinin, alpha 1
chr5_-_10814179	0.738		DAP	death-associated protein

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.35	9.05e-31	GO:0044260	cellular macromolecule metabolic process
1.25	5.28e-27	GO:0044237	cellular metabolic process
1.28	6.78e-23	GO:0043170	macromolecule metabolic process
1.12	2.97e-21	GO:0009987	cellular process
1.22	4.16e-21	GO:0044238	primary metabolic process
1.33	5.91e-19	GO:0060255	regulation of macromolecule metabolic process
1.19	3.62e-18	GO:0008152	metabolic process
1.19	5.86e-18	GO:0050794	regulation of cellular process
1.29	6.12e-18	GO:0019222	regulation of metabolic process
1.38	7.11e-18	GO:0010468	regulation of gene expression
1.31	8.29e-18	GO:0031323	regulation of cellular metabolic process
1.18	1.23e-17	GO:0050789	regulation of biological process
1.36	6.07e-17	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16	5.44e-16	GO:0065007	biological regulation
1.30	6.43e-16	GO:0080090	regulation of primary metabolic process
1.36	1.75e-15	GO:0044267	cellular protein metabolic process
1.38	2.69e-15	GO:0051252	regulation of RNA metabolic process
1.36	3.19e-15	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.36	4.10e-15	GO:0010556	regulation of macromolecule biosynthetic process
1.42	1.67e-14	GO:0006464	protein modification process
2.00	3.43e-14	GO:0016568	chromatin modification
1.43	6.22e-14	GO:0016070	RNA metabolic process
1.33	1.15e-13	GO:0009889	regulation of biosynthetic process
1.39	1.43e-13	GO:0043412	macromolecule modification
1.32	3.87e-13	GO:0031326	regulation of cellular biosynthetic process
1.36	1.41e-12	GO:0006355	regulation of transcription, DNA-dependent
1.56	1.78e-12	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.28	3.48e-12	GO:0034641	cellular nitrogen compound metabolic process
1.27	5.71e-12	GO:0006807	nitrogen compound metabolic process
1.34	8.44e-12	GO:0090304	nucleic acid metabolic process
1.30	2.57e-11	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27	2.18e-10	GO:0019538	protein metabolic process
1.28	2.37e-10	GO:0051171	regulation of nitrogen compound metabolic process
1.38	4.94e-10	GO:0006996	organelle organization
1.53	8.79e-10	GO:0006351	transcription, DNA-dependent
1.45	1.04e-09	GO:0010604	positive regulation of macromolecule metabolic process
1.32	1.40e-09	GO:0048523	negative regulation of cellular process
1.65	1.42e-09	GO:0010629	negative regulation of gene expression
1.43	2.75e-09	GO:0009893	positive regulation of metabolic process
1.30	3.35e-09	GO:0048519	negative regulation of biological process
2.16	5.05e-09	GO:0016569	covalent chromatin modification
2.17	5.44e-09	GO:0016570	histone modification
1.59	8.52e-09	GO:0051254	positive regulation of RNA metabolic process
1.42	1.86e-08	GO:0031325	positive regulation of cellular metabolic process
1.69	1.87e-08	GO:0006325	chromatin organization
1.33	2.74e-08	GO:0010467	gene expression
1.28	3.42e-08	GO:0048522	positive regulation of cellular process
1.56	8.24e-08	GO:0010628	positive regulation of gene expression
1.51	2.65e-07	GO:0010557	positive regulation of macromolecule biosynthetic process
1.56	2.89e-07	GO:0051276	chromosome organization
1.48	2.90e-07	GO:0009891	positive regulation of biosynthetic process
1.25	2.97e-07	GO:0048518	positive regulation of biological process
1.25	4.65e-07	GO:0071842	cellular component organization at cellular level
1.50	4.75e-07	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.74	5.36e-07	GO:0018193	peptidyl-amino acid modification
1.55	5.42e-07	GO:0045893	positive regulation of transcription, DNA-dependent
1.49	5.43e-07	GO:0051173	positive regulation of nitrogen compound metabolic process
1.47	7.73e-07	GO:0031328	positive regulation of cellular biosynthetic process
1.52	8.20e-07	GO:0031327	negative regulation of cellular biosynthetic process
1.52	9.63e-07	GO:0009890	negative regulation of biosynthetic process
1.83	9.93e-07	GO:0032446	protein modification by small protein conjugation
1.42	1.17e-06	GO:0009892	negative regulation of metabolic process
1.43	1.38e-06	GO:0032774	RNA biosynthetic process
1.24	1.48e-06	GO:0071841	cellular component organization or biogenesis at cellular level
1.54	1.59e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.36	1.86e-06	GO:0051641	cellular localization
1.74	1.95e-06	GO:0070647	protein modification by small protein conjugation or removal
1.58	2.01e-06	GO:0051253	negative regulation of RNA metabolic process
1.58	2.65e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.43	2.79e-06	GO:0010605	negative regulation of macromolecule metabolic process
1.31	2.82e-06	GO:0034645	cellular macromolecule biosynthetic process
1.51	4.05e-06	GO:0010558	negative regulation of macromolecule biosynthetic process
1.30	4.42e-06	GO:0009059	macromolecule biosynthetic process
1.82	5.35e-06	GO:0016567	protein ubiquitination
1.38	8.27e-06	GO:0051649	establishment of localization in cell
1.50	3.48e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.62	4.08e-05	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.44	4.28e-05	GO:0016192	vesicle-mediated transport
2.26	4.63e-05	GO:0040029	regulation of gene expression, epigenetic
1.23	5.42e-05	GO:0044249	cellular biosynthetic process
1.35	5.88e-05	GO:0044248	cellular catabolic process
1.40	7.06e-05	GO:0031324	negative regulation of cellular metabolic process
1.37	7.17e-05	GO:0032268	regulation of cellular protein metabolic process
1.82	7.27e-05	GO:0048011	nerve growth factor receptor signaling pathway
1.52	7.90e-05	GO:0044265	cellular macromolecule catabolic process
1.28	8.39e-05	GO:0023051	regulation of signaling
1.22	8.84e-05	GO:0009058	biosynthetic process
1.48	9.26e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.19	9.46e-05	GO:0016043	cellular component organization
1.18	1.16e-04	GO:0071840	cellular component organization or biogenesis
1.51	1.24e-04	GO:0016071	mRNA metabolic process
1.41	1.73e-04	GO:0046907	intracellular transport
1.31	2.52e-04	GO:0033036	macromolecule localization
1.51	3.35e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.45	4.66e-04	GO:0009057	macromolecule catabolic process
2.33	7.79e-04	GO:0000209	protein polyubiquitination
1.33	7.96e-04	GO:0051246	regulation of protein metabolic process
1.28	9.91e-04	GO:0007399	nervous system development
1.66	1.01e-03	GO:0010608	posttranscriptional regulation of gene expression
1.42	1.36e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.28	1.78e-03	GO:0009966	regulation of signal transduction
1.97	1.86e-03	GO:0006403	RNA localization
1.32	1.86e-03	GO:0008104	protein localization
2.38	1.99e-03	GO:0016458	gene silencing
1.54	2.61e-03	GO:0006397	mRNA processing
1.27	3.05e-03	GO:0009056	catabolic process
1.59	3.19e-03	GO:0006511	ubiquitin-dependent protein catabolic process
1.35	3.54e-03	GO:0045184	establishment of protein localization
1.58	4.56e-03	GO:0019941	modification-dependent protein catabolic process
1.39	4.85e-03	GO:0009790	embryo development
2.70	5.97e-03	GO:0031047	gene silencing by RNA
1.57	6.34e-03	GO:0043632	modification-dependent macromolecule catabolic process
1.56	6.55e-03	GO:0009259	ribonucleotide metabolic process
1.17	6.67e-03	GO:0051234	establishment of localization
2.13	7.19e-03	GO:0018205	peptidyl-lysine modification
1.34	7.21e-03	GO:0015031	protein transport
1.57	7.33e-03	GO:0009150	purine ribonucleotide metabolic process
1.85	8.49e-03	GO:0006184	GTP catabolic process
1.17	8.71e-03	GO:0006810	transport
1.55	8.88e-03	GO:0051603	proteolysis involved in cellular protein catabolic process
1.53	9.57e-03	GO:0044419	interspecies interaction between organisms
2.95	9.94e-03	GO:0070936	protein K48-linked ubiquitination
1.46	1.08e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.92	1.10e-02	GO:0050657	nucleic acid transport
1.92	1.10e-02	GO:0050658	RNA transport
1.92	1.10e-02	GO:0051236	establishment of RNA localization
1.48	1.13e-02	GO:0043066	negative regulation of apoptosis
1.70	1.20e-02	GO:0006457	protein folding
1.57	1.46e-02	GO:0006366	transcription from RNA polymerase II promoter
1.75	1.64e-02	GO:0043687	post-translational protein modification
1.79	1.70e-02	GO:0046039	GTP metabolic process
1.51	1.72e-02	GO:0030163	protein catabolic process
1.30	1.75e-02	GO:0042981	regulation of apoptosis
1.46	1.94e-02	GO:0043069	negative regulation of programmed cell death
4.42	2.02e-02	GO:0045815	positive regulation of gene expression, epigenetic
1.52	2.24e-02	GO:0044257	cellular protein catabolic process
1.15	2.28e-02	GO:0051179	localization
2.23	2.50e-02	GO:0018394	peptidyl-lysine acetylation
1.60	3.05e-02	GO:0072523	purine-containing compound catabolic process
1.14	3.12e-02	GO:0032502	developmental process
1.35	3.19e-02	GO:0019220	regulation of phosphate metabolic process
1.35	3.19e-02	GO:0051174	regulation of phosphorus metabolic process
1.44	3.20e-02	GO:0060548	negative regulation of cell death
1.28	3.40e-02	GO:0043067	regulation of programmed cell death
2.19	3.64e-02	GO:0006475	internal protein amino acid acetylation
1.33	3.80e-02	GO:0031399	regulation of protein modification process
2.22	3.90e-02	GO:0016573	histone acetylation
1.14	4.01e-02	GO:0007275	multicellular organismal development
1.60	4.08e-02	GO:0006195	purine nucleotide catabolic process
1.29	4.27e-02	GO:0006793	phosphorus metabolic process
1.29	4.27e-02	GO:0006796	phosphate metabolic process
1.62	4.32e-02	GO:0009261	ribonucleotide catabolic process
2.12	4.42e-02	GO:0006473	protein acetylation
1.51	4.60e-02	GO:0033043	regulation of organelle organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.19	8.96e-64	GO:0044424	intracellular part
1.18	2.13e-62	GO:0005622	intracellular
1.20	5.08e-46	GO:0043226	organelle
1.20	4.61e-45	GO:0043229	intracellular organelle
1.23	2.45e-44	GO:0043227	membrane-bounded organelle
1.22	1.42e-43	GO:0043231	intracellular membrane-bounded organelle
1.32	4.18e-38	GO:0005634	nucleus
1.19	2.39e-28	GO:0005737	cytoplasm
1.43	1.78e-20	GO:0044428	nuclear part
1.47	7.02e-20	GO:0031981	nuclear lumen
1.22	2.29e-17	GO:0044446	intracellular organelle part
1.21	1.50e-16	GO:0044422	organelle part
1.49	7.57e-15	GO:0005654	nucleoplasm
1.19	1.48e-14	GO:0044444	cytoplasmic part
1.35	2.36e-14	GO:0070013	intracellular organelle lumen
1.34	5.61e-14	GO:0031974	membrane-enclosed lumen
1.05	6.14e-14	GO:0044464	cell part
1.05	6.71e-14	GO:0005623	cell
1.34	8.33e-14	GO:0043233	organelle lumen
1.36	1.57e-13	GO:0005829	cytosol
1.28	4.01e-12	GO:0043234	protein complex
1.24	1.60e-11	GO:0032991	macromolecular complex
1.52	1.71e-08	GO:0044451	nucleoplasm part
2.46	2.34e-07	GO:0016585	chromatin remodeling complex
3.82	1.77e-04	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.36	3.16e-04	GO:0031982	vesicle
1.18	4.89e-04	GO:0043228	non-membrane-bounded organelle
1.18	4.89e-04	GO:0043232	intracellular non-membrane-bounded organelle
1.25	5.83e-04	GO:0012505	endomembrane system
1.36	8.61e-04	GO:0031410	cytoplasmic vesicle
1.19	2.68e-03	GO:0031090	organelle membrane
1.35	2.87e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.34	2.95e-03	GO:0031988	membrane-bounded vesicle
1.39	3.29e-03	GO:0044431	Golgi apparatus part
2.23	3.88e-03	GO:0000123	histone acetyltransferase complex
1.49	4.75e-03	GO:0048471	perinuclear region of cytoplasm
2.32	7.04e-03	GO:0035770	RNA granule
1.99	7.68e-03	GO:0042470	melanosome
1.99	7.68e-03	GO:0048770	pigment granule
1.39	1.49e-02	GO:0005730	nucleolus
1.98	1.97e-02	GO:0000790	nuclear chromatin
1.39	2.07e-02	GO:0000139	Golgi membrane
2.40	2.88e-02	GO:0008287	protein serine/threonine phosphatase complex
1.62	3.37e-02	GO:0031252	cell leading edge
2.53	4.45e-02	GO:0042641	actomyosin
3.69	4.60e-02	GO:0010494	stress granule

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.26	1.70e-41	GO:0005515	protein binding
1.13	8.39e-33	GO:0005488	binding
1.34	7.03e-21	GO:0003676	nucleic acid binding
1.38	3.64e-17	GO:0000166	nucleotide binding
1.58	9.03e-16	GO:0030528	transcription regulator activity
1.34	2.25e-13	GO:0003677	DNA binding
1.52	7.87e-10	GO:0003723	RNA binding
1.32	4.49e-09	GO:0017076	purine nucleotide binding
1.32	5.95e-09	GO:0032553	ribonucleotide binding
1.32	5.95e-09	GO:0032555	purine ribonucleotide binding
1.32	1.01e-08	GO:0035639	purine ribonucleoside triphosphate binding
1.73	2.74e-08	GO:0000988	protein binding transcription factor activity
1.73	2.74e-08	GO:0000989	transcription factor binding transcription factor activity
1.44	3.46e-08	GO:0001071	nucleic acid binding transcription factor activity
1.44	3.46e-08	GO:0003700	sequence-specific DNA binding transcription factor activity
1.72	4.83e-08	GO:0003712	transcription cofactor activity
1.78	8.47e-08	GO:0016563	transcription activator activity
1.79	1.57e-07	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.50	3.52e-07	GO:0043565	sequence-specific DNA binding
1.86	8.09e-07	GO:0019787	small conjugating protein ligase activity
1.78	1.85e-06	GO:0016881	acid-amino acid ligase activity
1.72	2.54e-06	GO:0016564	transcription repressor activity
1.30	4.06e-06	GO:0030554	adenyl nucleotide binding
1.30	6.32e-06	GO:0032559	adenyl ribonucleotide binding
1.25	8.48e-06	GO:0008270	zinc ion binding
1.42	1.40e-05	GO:0016301	kinase activity
1.29	1.90e-05	GO:0005524	ATP binding
1.38	2.68e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.26	3.30e-05	GO:0016740	transferase activity
1.84	5.85e-05	GO:0003682	chromatin binding
1.13	6.16e-05	GO:0003824	catalytic activity
1.53	6.57e-05	GO:0016874	ligase activity
1.41	7.42e-05	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.77	7.89e-05	GO:0004842	ubiquitin-protein ligase activity
1.54	9.78e-05	GO:0004674	protein serine/threonine kinase activity
1.65	1.07e-04	GO:0008134	transcription factor binding
1.74	2.19e-04	GO:0003713	transcription coactivator activity
1.37	6.98e-04	GO:0019899	enzyme binding
1.41	7.96e-04	GO:0004672	protein kinase activity
1.70	1.28e-03	GO:0003924	GTPase activity
1.70	1.71e-03	GO:0000975	regulatory region DNA binding
1.70	1.71e-03	GO:0001067	regulatory region nucleic acid binding
1.70	1.71e-03	GO:0044212	transcription regulatory region DNA binding
1.70	3.24e-03	GO:0010843	promoter binding
2.83	3.36e-03	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
1.19	3.47e-03	GO:0046914	transition metal ion binding
1.13	5.03e-03	GO:0046872	metal ion binding
1.78	6.67e-03	GO:0003714	transcription corepressor activity
1.44	7.41e-03	GO:0019904	protein domain specific binding
1.58	1.05e-02	GO:0003702	RNA polymerase II transcription factor activity
1.13	1.09e-02	GO:0043169	cation binding
1.13	1.31e-02	GO:0043167	ion binding
2.09	1.67e-02	GO:0042393	histone binding
1.98	2.02e-02	GO:0035257	nuclear hormone receptor binding
1.99	3.87e-02	GO:0031625	ubiquitin protein ligase binding