Motif ID: EHF.p2

Z-value: 4.598


Transcription factors associated with EHF.p2:

Gene SymbolEntrez IDGene Name
EHF 26298 ets homologous factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EHFchr11_+_345992270.302.6e-01Click!


Activity profile for motif EHF.p2.

activity profile for motif EHF.p2


Sorted Z-values histogram for motif EHF.p2

Sorted Z-values for motif EHF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EHF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_21361901 5.629 MKRN3
makorin ring finger protein 3
chr13_-_113151453 5.461 NM_199162
ADPRHL1
ADP-ribosylhydrolase like 1
chr3_+_11242666 4.277 NM_001098211
HRH1
histamine receptor H1
chr8_+_15442123 3.397 TUSC3
tumor suppressor candidate 3
chr10_+_12278200 2.867 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr8_+_15442106 2.831 TUSC3
tumor suppressor candidate 3
chr10_+_12278185 2.716 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr1_+_202097346 2.658 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr10_+_12278213 2.584 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr12_+_11694172 2.577 ETV6
ets variant 6
chr17_+_55139793 2.574 VMP1
vacuole membrane protein 1
chr3_+_9809776 2.571 NM_001198780
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr1_+_202097355 2.504 NM_003094
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr8_+_15442100 2.495 NM_006765
NM_178234
TUSC3

tumor suppressor candidate 3

chr17_+_55139792 2.452 VMP1
vacuole membrane protein 1
chr10_-_12278026 2.424 NM_014142
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr6_+_33347776 2.391 NM_022551
RPS18
ribosomal protein S18
chr17_+_55139743 2.370 VMP1
vacuole membrane protein 1
chr10_-_12277846 2.359 NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr6_-_33347563 2.346 NM_022553
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr17_+_55139807 2.337 VMP1
vacuole membrane protein 1
chr6_+_33347833 2.307 RPS18
ribosomal protein S18
chr7_-_91713044 2.274 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr7_-_135312574 2.271 MTPN
myotrophin
chr2_+_174968701 2.238 NM_001193528
NM_024583
SCRN3

secernin 3

chr11_+_384238 2.207 PKP3
plakophilin 3
chr17_+_55139841 2.206 VMP1
vacuole membrane protein 1
chrX_-_131179598 2.174 NM_021183
RAP2C
RAP2C, member of RAS oncogene family
chr22_+_20350272 2.165 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr3_+_151747204 2.156 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr15_+_21361546 2.149 NM_005664
MKRN3
makorin ring finger protein 3
chr11_+_8660913 2.148 RPL27A
ribosomal protein L27a
chr1_-_167603623 2.111 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr1_+_171950684 2.084 NM_014458
KLHL20
kelch-like 20 (Drosophila)
chr10_+_12277935 2.081 NM_006023
CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr6_-_116488458 2.054 NM_002031
FRK
fyn-related kinase
chr15_-_31147376 2.045 NM_001103184
FMN1
formin 1
chr11_+_65526349 2.030 BANF1
barrier to autointegration factor 1
chr7_+_99451110 2.018 NM_003439
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr11_+_111294810 2.002 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr22_+_19543248 2.000 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chr11_+_384199 1.997 NM_007183
PKP3
plakophilin 3
chr1_-_164004730 1.988 NM_019026
TMCO1
transmembrane and coiled-coil domains 1
chr11_+_65526277 1.987 BANF1
barrier to autointegration factor 1
chr3_-_71262405 1.986 FOXP1
forkhead box P1
chr11_-_128399218 1.966 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr16_-_30993004 1.958 NM_024706
ZNF668
zinc finger protein 668
chr16_+_30993223 1.953 NM_014699
ZNF646
zinc finger protein 646
chr22_-_19543099 1.953 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr6_-_33347417 1.952 VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr2_+_174968751 1.944 SCRN3
secernin 3
chr11_+_65526462 1.940 BANF1
barrier to autointegration factor 1
chr11_+_111294868 1.933 C11orf52
chromosome 11 open reading frame 52
chr1_-_143706196 1.926 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_+_202097386 1.925 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr6_-_166676016 1.920 SFT2D1
SFT2 domain containing 1
chr1_+_40496317 1.911 NM_005857
ZMPSTE24
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr1_+_40279036 1.907 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr14_-_44500840 1.902 KLHL28
kelch-like 28 (Drosophila)
chr1_+_167603817 1.899 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr1_+_171950759 1.891 KLHL20
kelch-like 20 (Drosophila)
chr7_-_128482059 1.888 TNPO3
transportin 3
chr6_-_166675980 1.873 NM_145169
SFT2D1
SFT2 domain containing 1
chr2_-_174968595 1.865 NM_004882
CIR1
corepressor interacting with RBPJ, 1
chr16_+_30993252 1.862 ZNF646
zinc finger protein 646
chr1_-_164004611 1.855 TMCO1
transmembrane and coiled-coil domains 1
chr15_+_94676691 1.843 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr7_+_107171809 1.838 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr6_-_49538810 1.834 NM_000255
MUT
methylmalonyl CoA mutase
chr3_-_71262426 1.824 FOXP1
forkhead box P1
chr1_+_40279023 1.817 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr1_-_205272619 1.814 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr1_-_143706265 1.813 PDE4DIP
phosphodiesterase 4D interacting protein
chr11_-_46678736 1.813 ARHGAP1
Rho GTPase activating protein 1
chr7_+_91713347 1.780 NM_019004
ANKIB1
ankyrin repeat and IBR domain containing 1
chr16_+_67724023 1.780 CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr4_-_140224794 1.778 ELF2
E74-like factor 2 (ets domain transcription factor)
chr8_-_95634845 1.749 NM_015496
NM_183009
KIAA1429

KIAA1429

chr11_-_46678691 1.745 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr16_-_70400232 1.741 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr5_+_140719773 1.740 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr16_-_70400040 1.722 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr19_-_56214765 1.722 NM_145888
KLK10
kallikrein-related peptidase 10
chr11_-_46678715 1.721 ARHGAP1
Rho GTPase activating protein 1
chr22_-_19543069 1.712 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr6_-_11887265 1.694 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chrX_-_119578899 1.689 CUL4B
cullin 4B
chr2_+_138438277 1.684 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr1_+_43628186 1.683 C1orf84
chromosome 1 open reading frame 84
chr8_+_100094669 1.672 NM_015243
NM_017890
NM_152564
NM_181661
VPS13B



vacuolar protein sorting 13 homolog B (yeast)



chr5_+_140051404 1.663 HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr1_-_71319265 1.662 ZRANB2
zinc finger, RAN-binding domain containing 2
chr17_+_55139644 1.655 NM_030938
VMP1
vacuole membrane protein 1
chr17_+_24013359 1.643 NM_003170
SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chr7_-_91713232 1.642 NM_194455
NM_194456
KRIT1

KRIT1, ankyrin repeat containing

chr4_+_144325502 1.641 NM_032557
USP38
ubiquitin specific peptidase 38
chr5_+_87600485 1.638 LOC100505894
hypothetical LOC100505894
chr7_-_128482354 1.629 TNPO3
transportin 3
chr1_+_167604056 1.624 BLZF1
basic leucine zipper nuclear factor 1
chr1_+_40279010 1.622 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr1_-_52642646 1.618 NM_001190818
NM_001190819
NM_004153
ORC1


origin recognition complex, subunit 1


chr12_+_49080858 1.610 NM_001170803
NM_001170804
NM_001170808
NM_052879
NM_199188
NM_199190
LARP4





La ribonucleoprotein domain family, member 4





chr2_+_169367345 1.607 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr18_+_3443771 1.605 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr19_+_61624 1.602 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chrX_-_67569894 1.598 NM_002547
OPHN1
oligophrenin 1
chr1_-_158579680 1.588 COPA
coatomer protein complex, subunit alpha
chr3_+_15444056 1.587 NM_033083
EAF1
ELL associated factor 1
chr11_+_46678892 1.586 NM_024741
ZNF408
zinc finger protein 408
chr1_-_40496161 1.585


chr7_+_98844586 1.583 BUD31
BUD31 homolog (S. cerevisiae)
chr2_+_157822355 1.576 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr17_+_24013320 1.576 SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chrX_+_11039326 1.576 NM_001122608
NM_001171991
NM_005333
HCCS


holocytochrome c synthase


chr19_+_57648570 1.575 NM_001099694
ZNF578
zinc finger protein 578
chr6_-_31617704 1.574 DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr6_-_43592670 1.574 YIPF3
Yip1 domain family, member 3
chr1_-_43410235 1.574 EBNA1BP2
EBNA1 binding protein 2
chr4_-_84031294 1.564 SEC31A
SEC31 homolog A (S. cerevisiae)
chrX_+_131179886 1.563


chr1_+_112963979 1.556 CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr1_-_158579653 1.546 COPA
coatomer protein complex, subunit alpha
chr5_-_87600371 1.545 NM_153354
TMEM161B
transmembrane protein 161B
chr6_+_10663934 1.536 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr18_+_3252110 1.534 NM_033546
MYL12B
myosin, light chain 12B, regulatory
chr1_-_158579583 1.526


chr5_+_158622843 1.523 UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr6_-_31728447 1.520 NM_004639
NM_080702
NM_080703
BAG6


BCL2-associated athanogene 6


chr4_-_84031358 1.520 NM_001191049
SEC31A
SEC31 homolog A (S. cerevisiae)
chr1_+_39229474 1.515 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr11_+_57192132 1.514 ZDHHC5
zinc finger, DHHC-type containing 5
chr18_+_3252184 1.511 MYL12B
myosin, light chain 12B, regulatory
chr7_-_135312387 1.511 MTPN
myotrophin
chr16_+_67723988 1.509 NM_032830
CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr1_+_40496425 1.509 ZMPSTE24
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr7_-_135312734 1.507 NM_145808
NM_001128619
MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr6_+_43592812 1.503 POLR1C
polymerase (RNA) I polypeptide C, 30kDa
chr6_-_85529884 1.499 TBX18
T-box 18
chr5_+_10303281 1.490 NM_012073
CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr1_-_9925908 1.489 LZIC
leucine zipper and CTNNBIP1 domain containing
chr17_-_55139538 1.485 NM_016077
PTRH2
peptidyl-tRNA hydrolase 2
chr15_+_72620570 1.481 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr2_+_17798605 1.474 NM_182625
LOC284952
GEN1
hypothetical protein LOC284952
Gen homolog 1, endonuclease (Drosophila)
chr22_+_19191964 1.467 MED15
mediator complex subunit 15
chr14_-_56805118 1.466


chr17_-_24013303 1.463 SDF2
stromal cell-derived factor 2
chr7_+_86619580 1.460 NM_001142326
NM_001142327
DMTF1

cyclin D binding myb-like transcription factor 1

chr1_+_112963972 1.451 CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr1_+_43628136 1.441 NM_001012961
C1orf84
chromosome 1 open reading frame 84
chr4_+_144325533 1.441 USP38
ubiquitin specific peptidase 38
chr5_+_140051325 1.437 HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr1_+_164004789 1.436 LOC100147773
hypothetical LOC100147773
chr8_+_100094677 1.434 VPS13B
vacuolar protein sorting 13 homolog B (yeast)
chr20_+_61374581 1.433 ARFGAP1
ADP-ribosylation factor GTPase activating protein 1
chr7_-_107997132 1.432 NM_182529
NM_001130475
THAP5

THAP domain containing 5

chr4_-_84031362 1.431 SEC31A
SEC31 homolog A (S. cerevisiae)
chr1_+_154964894 1.430 RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr4_-_84031329 1.427 SEC31A
SEC31 homolog A (S. cerevisiae)
chr2_+_33213111 1.427 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr4_-_103968104 1.426 NM_003340
NM_181886
NM_181888
NM_181889
UBE2D3



ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)



chr4_+_43185 1.425 NM_182524
ZNF595
ZNF718
zinc finger protein 595
zinc finger protein 718
chr2_-_119322228 1.425 NM_001426
EN1
engrailed homeobox 1
chrX_+_11039380 1.416 HCCS
holocytochrome c synthase
chr21_-_37561495 1.414 NM_006052
DSCR3
Down syndrome critical region gene 3
chr12_-_32940931 1.413 NM_001005242
NM_004572
PKP2

plakophilin 2

chr6_+_43592758 1.410 NM_004875
NM_203290
POLR1C

polymerase (RNA) I polypeptide C, 30kDa

chr4_-_84031349 1.402 SEC31A
SEC31 homolog A (S. cerevisiae)
chr7_+_107997527 1.397 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr17_-_10541548 1.387 NM_004589
SCO1
SCO cytochrome oxidase deficient homolog 1 (yeast)
chr6_-_29081015 1.379 NM_001010877
ZNF311
zinc finger protein 311
chr15_-_40236061 1.375 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr7_+_75515355 1.373 MDH2
malate dehydrogenase 2, NAD (mitochondrial)
chr2_+_65308332 1.371 NM_001005386
NM_005722
ACTR2

ARP2 actin-related protein 2 homolog (yeast)

chr6_-_31728121 1.366 NM_001098534
BAG6
BCL2-associated athanogene 6
chr21_+_36614347 1.366 NM_015358
MORC3
MORC family CW-type zinc finger 3
chr5_+_10303377 1.364 CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr7_+_98844480 1.364 NM_003910
BUD31
BUD31 homolog (S. cerevisiae)
chr1_+_158579796 1.362 NCSTN
nicastrin
chr2_-_9613336 1.357 NM_003183
ADAM17
ADAM metallopeptidase domain 17
chr5_+_7449030 1.352 NM_020546
ADCY2
adenylate cyclase 2 (brain)
chr7_+_98994129 1.346 ZNF655
zinc finger protein 655
chr11_-_65526153 1.343 NM_032325
EIF1AD
eukaryotic translation initiation factor 1A domain containing
chr1_-_43410556 1.341 NM_006824
NM_001159936
EBNA1BP2

EBNA1 binding protein 2

chr8_+_38153223 1.331 NM_004874
BAG4
BCL2-associated athanogene 4
chr6_-_31728405 1.331 BAG6
BCL2-associated athanogene 6
chr1_+_40496494 1.330 ZMPSTE24
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr11_+_111450177 1.329 NM_001082969
NM_001082970
NM_018195
C11orf57


chromosome 11 open reading frame 57


chr16_+_67724039 1.329 CIRH1A
cirrhosis, autosomal recessive 1A (cirhin)
chr11_-_60954031 1.327 NM_001136040
NM_001142565
CPSF7

cleavage and polyadenylation specific factor 7, 59kDa

chr15_-_32181363 1.324 C15orf24
chromosome 15 open reading frame 24
chr4_-_84031396 1.323 NM_001077206
NM_001077207
NM_001077208
NM_016211
NM_014933
SEC31A




SEC31 homolog A (S. cerevisiae)




chr18_+_54039818 1.319 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chrX_-_153428621 1.315 G6PD
glucose-6-phosphate dehydrogenase
chr1_-_54291378 1.313 TMEM59
transmembrane protein 59
chr1_-_43628060 1.310 NM_052877
NM_201542
MED8

mediator complex subunit 8

chr22_+_19543350 1.306 SNAP29
synaptosomal-associated protein, 29kDa
chr14_-_76993641 1.306 NM_001193314
NM_001193315
NM_001193316
NM_001193317
NM_022067
VIPAR




VPS33B interacting protein, apical-basolateral polarity regulator




chr1_+_148747110 1.306 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr3_+_151747266 1.305 EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr1_+_40278993 1.304 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 1.41e-40 GO:0044260 cellular macromolecule metabolic process
1.37 7.96e-34 GO:0043170 macromolecule metabolic process
1.60 1.68e-31 GO:0090304 nucleic acid metabolic process
1.51 3.89e-30 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.63 2.37e-28 GO:0010467 gene expression
1.65 1.00e-27 GO:0016070 RNA metabolic process
2.16 1.96e-23 GO:0016071 mRNA metabolic process
2.03 8.12e-23 GO:0006396 RNA processing
1.25 1.59e-22 GO:0044237 cellular metabolic process
1.39 2.20e-20 GO:0034641 cellular nitrogen compound metabolic process
1.24 3.14e-20 GO:0044238 primary metabolic process
1.37 6.45e-19 GO:0006807 nitrogen compound metabolic process
1.43 1.75e-18 GO:0044267 cellular protein metabolic process
2.22 1.86e-18 GO:0006397 mRNA processing
2.71 3.70e-18 GO:0000375 RNA splicing, via transesterification reactions
2.72 7.26e-18 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.72 7.26e-18 GO:0000398 nuclear mRNA splicing, via spliceosome
2.34 3.17e-17 GO:0008380 RNA splicing
2.14 4.36e-17 GO:0016032 viral reproduction
1.20 1.17e-16 GO:0008152 metabolic process
1.49 1.24e-14 GO:0034645 cellular macromolecule biosynthetic process
1.48 1.95e-14 GO:0009059 macromolecule biosynthetic process
1.31 6.25e-14 GO:0071840 cellular component organization or biogenesis
2.48 5.09e-13 GO:0022613 ribonucleoprotein complex biogenesis
1.32 1.31e-12 GO:0019538 protein metabolic process
1.34 2.41e-12 GO:0071841 cellular component organization or biogenesis at cellular level
1.86 2.48e-12 GO:0044265 cellular macromolecule catabolic process
1.66 2.94e-12 GO:0015031 protein transport
1.63 1.28e-11 GO:0045184 establishment of protein localization
1.56 1.29e-11 GO:0008104 protein localization
2.10 1.54e-11 GO:0006412 translation
1.76 1.66e-11 GO:0009057 macromolecule catabolic process
2.35 1.87e-11 GO:0071843 cellular component biogenesis at cellular level
1.28 1.66e-10 GO:0016043 cellular component organization
1.99 3.58e-10 GO:0044257 cellular protein catabolic process
1.79 4.74e-10 GO:0006974 response to DNA damage stimulus
1.99 5.67e-10 GO:0051603 proteolysis involved in cellular protein catabolic process
1.95 5.85e-10 GO:0030163 protein catabolic process
2.01 8.73e-10 GO:0006511 ubiquitin-dependent protein catabolic process
1.62 9.53e-10 GO:0046907 intracellular transport
1.99 1.44e-09 GO:0019941 modification-dependent protein catabolic process
1.98 2.32e-09 GO:0043632 modification-dependent macromolecule catabolic process
1.30 8.94e-09 GO:0071842 cellular component organization at cellular level
1.44 1.59e-08 GO:0033036 macromolecule localization
1.38 8.81e-08 GO:0006996 organelle organization
1.53 2.75e-07 GO:0033554 cellular response to stress
2.39 9.88e-07 GO:0042254 ribosome biogenesis
1.45 2.07e-06 GO:0007049 cell cycle
1.42 2.28e-06 GO:0044248 cellular catabolic process
2.19 2.58e-06 GO:0010498 proteasomal protein catabolic process
2.19 2.58e-06 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
2.78 2.78e-06 GO:0006353 transcription termination, DNA-dependent
1.08 3.29e-06 GO:0009987 cellular process
1.52 5.10e-06 GO:0016192 vesicle-mediated transport
1.87 6.65e-06 GO:0010608 posttranscriptional regulation of gene expression
1.40 7.03e-06 GO:0044085 cellular component biogenesis
1.78 8.22e-06 GO:0070647 protein modification by small protein conjugation or removal
1.44 9.83e-06 GO:0032774 RNA biosynthetic process
1.26 1.33e-05 GO:0044249 cellular biosynthetic process
1.38 1.44e-05 GO:0051641 cellular localization
1.47 1.44e-05 GO:0043933 macromolecular complex subunit organization
1.84 1.90e-05 GO:0032446 protein modification by small protein conjugation
2.56 1.93e-05 GO:0071826 ribonucleoprotein complex subunit organization
1.62 2.67e-05 GO:0034621 cellular macromolecular complex subunit organization
2.63 2.97e-05 GO:0006354 transcription elongation, DNA-dependent
1.86 3.26e-05 GO:0016567 protein ubiquitination
2.57 3.92e-05 GO:0022618 ribonucleoprotein complex assembly
2.77 4.72e-05 GO:0071158 positive regulation of cell cycle arrest
2.17 7.73e-05 GO:0048193 Golgi vesicle transport
1.24 1.20e-04 GO:0009058 biosynthetic process
1.38 1.30e-04 GO:0051649 establishment of localization in cell
1.33 1.44e-04 GO:0009056 catabolic process
2.76 1.47e-04 GO:0006368 transcription elongation from RNA polymerase II promoter
2.50 1.51e-04 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.56 2.00e-04 GO:0034613 cellular protein localization
2.72 2.33e-04 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.72 2.33e-04 GO:0072395 signal transduction involved in cell cycle checkpoint
2.72 2.33e-04 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.72 2.33e-04 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.72 2.33e-04 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.72 2.33e-04 GO:0072422 signal transduction involved in DNA damage checkpoint
2.72 2.33e-04 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.72 2.33e-04 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
2.58 2.42e-04 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.44 2.42e-04 GO:0022402 cell cycle process
2.49 2.62e-04 GO:0000216 M/G1 transition of mitotic cell cycle
2.49 2.62e-04 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.49 2.62e-04 GO:0071779 G1/S transition checkpoint
2.61 2.80e-04 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
1.52 2.94e-04 GO:0000278 mitotic cell cycle
1.55 2.98e-04 GO:0070727 cellular macromolecule localization
2.44 3.22e-04 GO:0051351 positive regulation of ligase activity
1.63 3.70e-04 GO:0006886 intracellular protein transport
1.76 6.11e-04 GO:0034660 ncRNA metabolic process
2.45 6.63e-04 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.18 7.82e-04 GO:0051320 S phase
2.42 9.56e-04 GO:0051443 positive regulation of ubiquitin-protein ligase activity
3.00 1.06e-03 GO:0006369 termination of RNA polymerase II transcription
3.00 1.06e-03 GO:0051650 establishment of vesicle localization
1.57 1.09e-03 GO:0016044 cellular membrane organization
1.49 1.09e-03 GO:0071822 protein complex subunit organization
2.37 1.13e-03 GO:2000045 regulation of G1/S transition of mitotic cell cycle
1.71 1.19e-03 GO:0006366 transcription from RNA polymerase II promoter
4.00 1.21e-03 GO:0048199 vesicle targeting, to, from or within Golgi
1.83 1.22e-03 GO:0033365 protein localization to organelle
2.17 1.30e-03 GO:0000084 S phase of mitotic cell cycle
2.33 1.31e-03 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.56 1.42e-03 GO:0061024 membrane organization
1.25 1.51e-03 GO:0043412 macromolecule modification
1.45 1.68e-03 GO:0022403 cell cycle phase
1.48 2.01e-03 GO:0006259 DNA metabolic process
2.70 2.25e-03 GO:0006521 regulation of cellular amino acid metabolic process
2.48 2.81e-03 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.78 3.08e-03 GO:0009261 ribonucleotide catabolic process
1.62 3.53e-03 GO:0006281 DNA repair
1.25 3.63e-03 GO:0006464 protein modification process
2.44 4.09e-03 GO:0072594 establishment of protein localization to organelle
2.26 4.27e-03 GO:0006415 translational termination
1.99 4.57e-03 GO:0019058 viral infectious cycle
1.78 4.85e-03 GO:0009203 ribonucleoside triphosphate catabolic process
1.78 4.85e-03 GO:0009207 purine ribonucleoside triphosphate catabolic process
2.19 5.15e-03 GO:0051340 regulation of ligase activity
2.08 5.20e-03 GO:0031570 DNA integrity checkpoint
2.27 5.25e-03 GO:0019080 viral genome expression
2.27 5.25e-03 GO:0019083 viral transcription
3.24 5.59e-03 GO:0006903 vesicle targeting
1.77 5.83e-03 GO:0009146 purine nucleoside triphosphate catabolic process
1.37 6.11e-03 GO:0016265 death
2.10 6.23e-03 GO:0000077 DNA damage checkpoint
1.37 6.60e-03 GO:0008219 cell death
2.35 6.89e-03 GO:0007173 epidermal growth factor receptor signaling pathway
2.17 6.90e-03 GO:0043241 protein complex disassembly
2.17 6.90e-03 GO:0043624 cellular protein complex disassembly
2.14 7.37e-03 GO:0006414 translational elongation
2.08 8.16e-03 GO:0032984 macromolecular complex disassembly
2.08 8.16e-03 GO:0034623 cellular macromolecular complex disassembly
2.08 8.16e-03 GO:0042770 signal transduction in response to DNA damage
2.37 8.37e-03 GO:0051352 negative regulation of ligase activity
2.37 8.37e-03 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.93 9.27e-03 GO:0000082 G1/S transition of mitotic cell cycle
2.32 9.66e-03 GO:0000209 protein polyubiquitination
1.74 1.00e-02 GO:0009143 nucleoside triphosphate catabolic process
1.74 1.00e-02 GO:0009154 purine ribonucleotide catabolic process
1.36 1.11e-02 GO:0006351 transcription, DNA-dependent
2.41 1.22e-02 GO:0033238 regulation of cellular amine metabolic process
2.29 1.34e-02 GO:0031123 RNA 3'-end processing
2.16 1.43e-02 GO:0051438 regulation of ubiquitin-protein ligase activity
1.40 1.59e-02 GO:0065003 macromolecular complex assembly
1.57 1.66e-02 GO:0051301 cell division
1.39 1.68e-02 GO:0012501 programmed cell death
1.32 1.72e-02 GO:0042981 regulation of apoptosis
1.61 1.79e-02 GO:0051325 interphase
1.78 2.06e-02 GO:0022411 cellular component disassembly
1.78 2.06e-02 GO:0071845 cellular component disassembly at cellular level
2.50 2.08e-02 GO:0046782 regulation of viral transcription
1.61 2.21e-02 GO:0009141 nucleoside triphosphate metabolic process
5.08 2.40e-02 GO:0048194 Golgi vesicle budding
5.08 2.40e-02 GO:0048200 Golgi transport vesicle coating
5.08 2.40e-02 GO:0048205 COPI coating of Golgi vesicle
1.39 2.56e-02 GO:0006915 apoptosis
2.01 2.87e-02 GO:0016197 endosome transport
2.01 2.87e-02 GO:0031398 positive regulation of protein ubiquitination
2.57 2.89e-02 GO:0050434 positive regulation of viral transcription
1.94 2.94e-02 GO:0007093 mitotic cell cycle checkpoint
2.36 2.99e-02 GO:0031124 mRNA 3'-end processing
3.34 3.01e-02 GO:0006901 vesicle coating
1.60 3.14e-02 GO:0051329 interphase of mitotic cell cycle
1.31 3.15e-02 GO:0043067 regulation of programmed cell death
1.41 3.15e-02 GO:0051726 regulation of cell cycle
1.64 3.68e-02 GO:0009166 nucleotide catabolic process
1.82 3.92e-02 GO:0022415 viral reproductive process
1.66 4.05e-02 GO:0006195 purine nucleotide catabolic process
1.60 4.15e-02 GO:0009199 ribonucleoside triphosphate metabolic process
1.30 4.53e-02 GO:0010941 regulation of cell death
1.35 4.63e-02 GO:0006508 proteolysis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 8.75e-55 GO:0044424 intracellular part
1.19 1.52e-53 GO:0005622 intracellular
1.23 1.30e-50 GO:0043229 intracellular organelle
1.23 2.03e-50 GO:0043226 organelle
1.26 5.56e-48 GO:0043231 intracellular membrane-bounded organelle
1.26 7.82e-48 GO:0043227 membrane-bounded organelle
1.35 7.66e-38 GO:0044446 intracellular organelle part
1.34 2.23e-37 GO:0005634 nucleus
1.33 2.45e-36 GO:0044422 organelle part
1.61 3.89e-34 GO:0044428 nuclear part
1.54 7.66e-29 GO:0031974 membrane-enclosed lumen
2.25 2.37e-28 GO:0030529 ribonucleoprotein complex
1.54 8.22e-28 GO:0070013 intracellular organelle lumen
1.61 8.71e-28 GO:0031981 nuclear lumen
1.40 1.98e-27 GO:0032991 macromolecular complex
1.53 2.79e-27 GO:0043233 organelle lumen
1.18 2.22e-21 GO:0005737 cytoplasm
1.57 7.31e-17 GO:0005654 nucleoplasm
1.21 9.59e-16 GO:0044444 cytoplasmic part
1.35 6.89e-15 GO:0043228 non-membrane-bounded organelle
1.35 6.89e-15 GO:0043232 intracellular non-membrane-bounded organelle
1.31 1.01e-12 GO:0043234 protein complex
2.62 2.09e-11 GO:0005681 spliceosomal complex
1.36 3.13e-11 GO:0005829 cytosol
1.78 9.04e-11 GO:0005730 nucleolus
2.97 2.22e-09 GO:0071013 catalytic step 2 spliceosome
1.58 8.41e-09 GO:0044451 nucleoplasm part
2.13 1.11e-07 GO:0005840 ribosome
2.39 1.70e-07 GO:0016607 nuclear speck
1.98 5.06e-07 GO:0016604 nuclear body
3.52 6.62e-07 GO:0030120 vesicle coat
2.77 4.61e-06 GO:0030117 membrane coat
2.77 4.61e-06 GO:0048475 coated membrane
1.04 4.79e-06 GO:0044464 cell part
2.81 5.03e-06 GO:0000502 proteasome complex
1.04 5.07e-06 GO:0005623 cell
1.25 3.26e-05 GO:0031090 organelle membrane
2.75 1.39e-04 GO:0005798 Golgi-associated vesicle
1.34 1.25e-03 GO:0005794 Golgi apparatus
3.14 1.78e-03 GO:0030532 small nuclear ribonucleoprotein complex
3.04 3.18e-03 GO:0030660 Golgi-associated vesicle membrane
2.24 5.37e-03 GO:0022626 cytosolic ribosome
1.41 7.55e-03 GO:0044431 Golgi apparatus part
4.09 8.34e-03 GO:0030663 COPI coated vesicle membrane
1.85 9.26e-03 GO:0000151 ubiquitin ligase complex
1.41 1.19e-02 GO:0005694 chromosome
4.29 1.25e-02 GO:0030126 COPI vesicle coat
2.14 2.18e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
1.77 2.29e-02 GO:0044445 cytosolic part
1.44 2.46e-02 GO:0005768 endosome
2.25 2.90e-02 GO:0015934 large ribosomal subunit
1.33 4.03e-02 GO:0031967 organelle envelope

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.89 5.57e-24 GO:0003723 RNA binding
1.22 1.50e-22 GO:0005515 protein binding
1.35 1.05e-18 GO:0003676 nucleic acid binding
1.10 1.76e-14 GO:0005488 binding
2.16 2.99e-06 GO:0003735 structural constituent of ribosome
1.87 3.41e-05 GO:0004842 ubiquitin-protein ligase activity
1.82 8.89e-05 GO:0019787 small conjugating protein ligase activity
1.24 1.02e-04 GO:0000166 nucleotide binding
2.23 1.34e-04 GO:0008026 ATP-dependent helicase activity
2.23 1.34e-04 GO:0070035 purine NTP-dependent helicase activity
3.07 1.52e-04 GO:0043021 ribonucleoprotein binding
1.43 2.02e-04 GO:0017111 nucleoside-triphosphatase activity
1.41 2.71e-04 GO:0016462 pyrophosphatase activity
1.72 2.97e-04 GO:0016881 acid-amino acid ligase activity
1.41 3.63e-04 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.40 4.83e-04 GO:0016817 hydrolase activity, acting on acid anhydrides
1.99 7.30e-04 GO:0004386 helicase activity
1.60 1.05e-03 GO:0016887 ATPase activity
1.50 1.88e-03 GO:0016874 ligase activity
2.26 2.24e-03 GO:0008135 translation factor activity, nucleic acid binding
1.61 3.65e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.22 6.64e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.22 1.01e-02 GO:0017076 purine nucleotide binding
3.61 1.10e-02 GO:0043022 ribosome binding
1.21 1.37e-02 GO:0032553 ribonucleotide binding
1.21 1.37e-02 GO:0032555 purine ribonucleotide binding
1.57 2.96e-02 GO:0042623 ATPase activity, coupled