Motif ID: ELF1,2,4.p2

Z-value: 3.292


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF1chr13_-_404543600.674.1e-03Click!
ELF2chr4_-_1402247940.621.0e-02Click!
ELF4chrX_-_129072333-0.504.8e-02Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_110653407 3.252 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr1_+_26358097 2.875 NM_024869
GRRP1
glycine/arginine rich protein 1
chr5_+_61910318 2.849 NM_181506
LRRC70
leucine rich repeat containing 70
chr13_-_30089509 2.399 HMGB1
high-mobility group box 1
chr18_+_3252184 2.315 MYL12B
myosin, light chain 12B, regulatory
chr19_-_53935648 2.252 NM_017805
RASIP1
Ras interacting protein 1
chr18_+_3252110 2.155 NM_033546
MYL12B
myosin, light chain 12B, regulatory
chr8_+_38153514 1.983 BAG4
BCL2-associated athanogene 4
chr9_+_115303527 1.982 NM_130795
RGS3
regulator of G-protein signaling 3
chr14_-_37795290 1.911 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr12_-_52939636 1.877 NM_001127321
CBX5
chromobox homolog 5
chr12_+_12829807 1.867 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr1_-_21478571 1.859 NM_001113347
ECE1
endothelin converting enzyme 1
chr17_-_44010543 1.849 NM_024015
HOXB4
homeobox B4
chr3_-_184756101 1.840 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr1_+_155130146 1.809 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr8_+_38153453 1.809 BAG4
BCL2-associated athanogene 4
chr8_+_38153223 1.793 NM_004874
BAG4
BCL2-associated athanogene 4
chr2_+_33514896 1.785 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr22_-_17892859 1.753 NM_001130861
NM_003277
CLDN5

claudin 5

chr14_-_37795001 1.727 CLEC14A
C-type lectin domain family 14, member A
chr6_-_46997579 1.721 NM_001098518
GPR116
G protein-coupled receptor 116
chr10_-_116434364 1.679 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr22_-_34566210 1.654 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_+_150044530 1.594 NM_130759
GIMAP1
GTPase, IMAP family member 1
chr14_+_62740878 1.556 NM_020663
RHOJ
ras homolog gene family, member J
chrX_-_50403412 1.551 SHROOM4
shroom family member 4
chr1_-_203867402 1.519 ELK4
ELK4, ETS-domain protein (SRF accessory protein 1)
chr3_-_50335113 1.508 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr22_-_34566276 1.501 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr8_-_6407882 1.486 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr17_+_29606408 1.484 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr4_+_91035025 1.466 NM_007351
MMRN1
multimerin 1
chr3_+_151747204 1.465 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr1_+_167604056 1.453 BLZF1
basic leucine zipper nuclear factor 1
chr14_-_56805118 1.437


chr8_-_38152985 1.408 NM_014462
LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chrX_-_131179598 1.392 NM_021183
RAP2C
RAP2C, member of RAS oncogene family
chr2_-_189752575 1.381 NM_000393
COL5A2
collagen, type V, alpha 2
chr17_+_24013320 1.378 SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chrX_+_15428820 1.372 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr5_-_102483680 1.367 NM_017676
GIN1
gypsy retrotransposon integrase 1
chr5_-_82409009 1.361 NM_174909
TMEM167A
transmembrane protein 167A
chr10_-_12278026 1.359 NM_014142
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr10_+_12278185 1.357 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr11_-_60953848 1.357 NM_024811
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr8_-_103735194 1.350 NM_001032282
KLF10
Kruppel-like factor 10
chrX_-_10504852 1.333 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr5_-_124108672 1.329 NM_020747
ZNF608
zinc finger protein 608
chr6_-_153365532 1.329 MTRF1L
mitochondrial translational release factor 1-like
chr22_-_34566367 1.328 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr1_+_118273869 1.317 WDR3
WD repeat domain 3
chr13_+_30089829 1.297 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr1_+_39229474 1.294 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr10_+_12278213 1.293 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr6_-_153365542 1.288 MTRF1L
mitochondrial translational release factor 1-like
chr18_-_51219880 1.287 TCF4
transcription factor 4
chr17_+_24013359 1.287 NM_003170
SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chr1_-_118273701 1.274 GDAP2
ganglioside induced differentiation associated protein 2
chr17_-_43288137 1.259 NM_199262
SP6
Sp6 transcription factor
chr9_-_35744271 1.255 NM_001044264
MSMP
microseminoprotein, prostate associated
chr9_-_88159076 1.252 ZCCHC6
zinc finger, CCHC domain containing 6
chr5_-_82408917 1.251 TMEM167A
transmembrane protein 167A
chr1_+_220953278 1.251 BROX
BRO1 domain and CAAX motif containing
chr1_+_220953351 1.251 BROX
BRO1 domain and CAAX motif containing
chr2_-_128138435 1.250 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr7_+_120416680 1.250 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr12_-_368517 1.242 KDM5A
lysine (K)-specific demethylase 5A
chr10_-_112668892 1.241 NM_001195304
NM_001195305
NM_001195307
BBIP1


BBSome interacting protein 1


chr12_-_52939584 1.237 NM_001127322
CBX5
chromobox homolog 5
chr1_+_118273887 1.232 NM_006784
WDR3
WD repeat domain 3
chr8_-_38153325 1.229 LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_-_40496161 1.221


chr1_+_143807876 1.215 SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr17_-_24013303 1.211 SDF2
stromal cell-derived factor 2
chr10_+_12278200 1.209 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr11_-_85457469 1.209 PICALM
phosphatidylinositol binding clathrin assembly protein
chr6_-_153365564 1.198 NM_001114184
NM_019041
MTRF1L

mitochondrial translational release factor 1-like

chr5_+_34951538 1.198 NM_018321
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr6_-_153365480 1.191 MTRF1L
mitochondrial translational release factor 1-like
chr5_+_82409072 1.181 NM_003401
NM_022406
NM_022550
XRCC4


X-ray repair complementing defective repair in Chinese hamster cells 4


chr4_-_48477038 1.168 NM_015030
FRYL
FRY-like
chr8_+_42515873 1.162 NM_138436
NM_001135674
NM_001135675
C8orf40


chromosome 8 open reading frame 40


chr4_-_48477021 1.160 FRYL
FRY-like
chr11_+_60954096 1.148 SDHAF2
succinate dehydrogenase complex assembly factor 2
chr14_-_74249492 1.147 NM_001039479
KIAA0317
KIAA0317
chr5_-_34951346 1.138 RAD1
RAD1 homolog (S. pombe)
chr5_-_102926349 1.127 NM_031438
NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr11_-_60954031 1.122 NM_001136040
NM_001142565
CPSF7

cleavage and polyadenylation specific factor 7, 59kDa

chr14_+_77244177 1.110 NM_031210
C14orf156
chromosome 14 open reading frame 156
chr6_-_47030492 1.108 NM_015234
GPR116
G protein-coupled receptor 116
chr21_+_44256630 1.105 NM_003274
TRAPPC10
trafficking protein particle complex 10
chrX_-_153908408 1.104 F8
coagulation factor VIII, procoagulant component
chr19_-_4510713 1.098 SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr3_+_9809776 1.097 NM_001198780
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr3_-_151746821 1.096 SERP1
stress-associated endoplasmic reticulum protein 1
chr17_-_24013259 1.095 SDF2
stromal cell-derived factor 2
chr3_+_185515543 1.093 NM_182917
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr10_-_51293220 1.077 NM_006327
TIMM23
TIMM23B
translocase of inner mitochondrial membrane 23 homolog (yeast)
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr12_+_8958397 1.075 NM_004426
PHC1
polyhomeotic homolog 1 (Drosophila)
chr10_+_114196698 1.073 NM_145206
VTI1A
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
chr1_+_202647097 1.071


chrX_-_79951838 1.069 NM_153252
BRWD3
bromodomain and WD repeat domain containing 3
chr11_-_72111027 1.064 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr5_-_34951470 1.064 NM_002853
RAD1
RAD1 homolog (S. pombe)
chr1_+_167603817 1.064 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr4_+_57028536 1.063 SRP72
signal recognition particle 72kDa
chr10_-_116434102 1.062 ABLIM1
actin binding LIM protein 1
chrX_+_114734074 1.061 NM_001136025
NM_001172335
PLS3

plastin 3

chr3_+_44665220 1.060 NM_003420
ZNF35
zinc finger protein 35
chr3_-_71262405 1.058 FOXP1
forkhead box P1
chr6_+_147567200 1.056 NM_001127715
NM_139244
STXBP5

syntaxin binding protein 5 (tomosyn)

chr5_+_102483856 1.049 PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chrX_+_153908426 1.047 FUNDC2
FUN14 domain containing 2
chr3_-_32519240 1.045 CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr3_-_71262426 1.039 FOXP1
forkhead box P1
chr10_-_27483144 1.039 YME1L1
YME1-like 1 (S. cerevisiae)
chr3_-_130362563 1.038 NM_020701
ISY1
ISY1 splicing factor homolog (S. cerevisiae)
chr3_-_193928038 1.034 NM_004113
FGF12
fibroblast growth factor 12
chr12_-_6103945 1.030 NM_000552
VWF
von Willebrand factor
chr15_+_21361901 1.029 MKRN3
makorin ring finger protein 3
chr1_+_143807748 1.026 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr1_+_84382562 1.025 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr14_+_74249599 1.025 NM_015962
FCF1
FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chr7_+_106293112 1.020 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr12_+_99185334 1.019 NM_017988
SCYL2
SCY1-like 2 (S. cerevisiae)
chr1_-_159369041 1.011 DEDD
death effector domain containing
chr2_-_144994349 1.008 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr9_+_76893232 1.005 OSTF1
osteoclast stimulating factor 1
chr10_+_12277935 1.004 NM_006023
CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr7_+_149842850 1.003 NM_153236
GIMAP7
GTPase, IMAP family member 7
chr7_+_44207131 1.000 YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr12_-_47774837 0.999 NM_021044
DHH
desert hedgehog
chr1_+_84382575 0.997 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_+_11694172 0.996 ETV6
ets variant 6
chr14_+_77244191 0.992 C14orf156
chromosome 14 open reading frame 156
chr15_-_40352765 0.986 NM_001110503
NM_015497
TMEM87A

transmembrane protein 87A

chr3_-_120878910 0.984 NM_005694
COX17
COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr10_+_114196977 0.980 VTI1A
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
chr8_+_125620523 0.979 NM_005005
NDUFB9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
chr12_+_120840829 0.974 NM_001178003
NM_144668
WDR66

WD repeat domain 66

chr1_+_84382529 0.972 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_-_60493985 0.969 NM_001048249
C5orf43
chromosome 5 open reading frame 43
chr8_-_42515774 0.969 SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr8_-_38153369 0.968 LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_-_159369081 0.968 NM_001039711
NM_032998
DEDD

death effector domain containing

chr7_-_91713044 0.967 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr5_+_78944151 0.963 PAPD4
PAP associated domain containing 4
chr6_+_43592812 0.959 POLR1C
polymerase (RNA) I polypeptide C, 30kDa
chr10_-_27483285 0.959 YME1L1
YME1-like 1 (S. cerevisiae)
chr7_+_44207094 0.954 NM_006555
YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr16_+_66131247 0.953 FAM65A
family with sequence similarity 65, member A
chr5_+_87600485 0.953 LOC100505894
hypothetical LOC100505894
chr4_+_2783743 0.951 NM_001145855
SH3BP2
SH3-domain binding protein 2
chr1_+_9926072 0.948 NM_022787
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr3_-_113763049 0.942 NM_022488
ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chr3_-_151746924 0.939 SERP1
stress-associated endoplasmic reticulum protein 1
chr6_-_76050837 0.937


chr3_-_32519323 0.937 CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr12_-_3732614 0.935 NM_001144958
NM_001144959
NM_032680
EFCAB4B


EF-hand calcium binding domain 4B


chr1_+_168030798 0.934 C1orf112
chromosome 1 open reading frame 112
chr9_+_123003549 0.934 GSN
gelsolin
chr7_-_27158726 0.933


chr8_+_56848552 0.931 TGS1
trimethylguanosine synthase 1
chr10_-_27483315 0.929 NM_014263
NM_139312
YME1L1

YME1-like 1 (S. cerevisiae)

chr1_+_40279036 0.928 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr14_-_77244073 0.923 NM_006020
ALKBH1
alkB, alkylation repair homolog 1 (E. coli)
chr13_-_51878235 0.922 THSD1
thrombospondin, type I, domain containing 1
chr11_+_10786137 0.918 LOC144017
hypothetical protein LOC144017
chr7_+_134114701 0.917 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr9_+_99435900 0.912 NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr3_+_29297806 0.912 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr5_-_87600371 0.905 NM_153354
TMEM161B
transmembrane protein 161B
chr18_+_64616296 0.904 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr19_-_20011013 0.903 NM_001077349
ZNF682
zinc finger protein 682
chrX_+_119622570 0.901 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr19_-_55008172 0.901 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr1_-_112963247 0.896 NM_017744
NM_138727
NM_138728
NM_138729
ST7L



suppression of tumorigenicity 7 like



chr5_-_60493903 0.895 C5orf43
chromosome 5 open reading frame 43
chr7_+_44207080 0.892 YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr6_+_151815298 0.890 C6orf211
chromosome 6 open reading frame 211
chr1_+_9926113 0.889 NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr8_-_68136881 0.886 COPS5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chr15_+_46271158 0.885 NM_001145668
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr7_+_106292975 0.884 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr15_+_75500284 0.884 NM_018200
HMG20A
high-mobility group 20A
chr9_-_26937165 0.884 PLAA
phospholipase A2-activating protein
chr8_-_68136700 0.884 COPS5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chrX_+_102518764 0.884 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr8_+_56848733 0.882


chr15_+_40353076 0.875 GANC
glucosidase, alpha; neutral C
chr12_-_70343656 0.875


chr1_-_158579583 0.873


chr1_-_118273728 0.866 NM_001135589
NM_017686
GDAP2

ganglioside induced differentiation associated protein 2

chr8_-_95634845 0.866 NM_015496
NM_183009
KIAA1429

KIAA1429

chr14_+_73423260 0.864 NM_021188
ZNF410
zinc finger protein 410
chr7_+_44207163 0.860 YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr3_-_151746970 0.860 NM_014445
SERP1
stress-associated endoplasmic reticulum protein 1
chr10_-_69504956 0.858 HERC4
hect domain and RLD 4
chr12_+_99185289 0.857 SCYL2
SCY1-like 2 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.30 3.63e-34 GO:0044260 cellular macromolecule metabolic process
1.26 2.67e-29 GO:0043170 macromolecule metabolic process
1.45 9.61e-26 GO:0010467 gene expression
1.39 9.30e-24 GO:0090304 nucleic acid metabolic process
1.34 1.51e-23 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19 2.36e-21 GO:0044237 cellular metabolic process
1.42 3.22e-21 GO:0016070 RNA metabolic process
1.17 1.33e-17 GO:0044238 primary metabolic process
1.15 7.18e-17 GO:0008152 metabolic process
1.64 2.53e-16 GO:0006396 RNA processing
1.30 5.40e-16 GO:0044267 cellular protein metabolic process
1.26 8.15e-16 GO:0034641 cellular nitrogen compound metabolic process
1.37 2.19e-15 GO:0009059 macromolecule biosynthetic process
1.37 4.28e-15 GO:0034645 cellular macromolecule biosynthetic process
1.25 5.07e-15 GO:0006807 nitrogen compound metabolic process
1.23 6.44e-14 GO:0071840 cellular component organization or biogenesis
1.62 1.10e-13 GO:0000278 mitotic cell cycle
1.65 1.27e-13 GO:0016071 mRNA metabolic process
1.26 1.57e-13 GO:0071841 cellular component organization or biogenesis at cellular level
1.35 1.65e-13 GO:0006996 organelle organization
1.84 3.80e-13 GO:0006412 translation
1.24 3.77e-12 GO:0019538 protein metabolic process
1.72 4.74e-12 GO:0006397 mRNA processing
1.51 1.06e-10 GO:0022403 cell cycle phase
1.21 1.23e-10 GO:0016043 cellular component organization
1.66 1.35e-10 GO:0016032 viral reproduction
1.46 3.00e-10 GO:0022402 cell cycle process
1.57 4.00e-10 GO:0044265 cellular macromolecule catabolic process
1.53 5.06e-10 GO:0009057 macromolecule catabolic process
1.24 6.23e-10 GO:0071842 cellular component organization at cellular level
1.38 4.07e-09 GO:0007049 cell cycle
1.07 5.82e-09 GO:0009987 cellular process
1.23 3.20e-08 GO:0044249 cellular biosynthetic process
1.67 3.44e-08 GO:0043632 modification-dependent macromolecule catabolic process
1.63 3.72e-08 GO:0030163 protein catabolic process
1.22 4.37e-08 GO:0009058 biosynthetic process
1.68 7.25e-08 GO:0048285 organelle fission
1.65 8.72e-08 GO:0051603 proteolysis involved in cellular protein catabolic process
1.67 8.76e-08 GO:0006511 ubiquitin-dependent protein catabolic process
1.41 9.71e-08 GO:0046907 intracellular transport
1.66 9.84e-08 GO:0019941 modification-dependent protein catabolic process
1.67 1.23e-07 GO:0000087 M phase of mitotic cell cycle
1.31 1.69e-07 GO:0033036 macromolecule localization
1.39 2.02e-07 GO:0015031 protein transport
1.63 2.13e-07 GO:0044257 cellular protein catabolic process
1.67 3.14e-07 GO:0000280 nuclear division
1.67 3.14e-07 GO:0007067 mitosis
1.38 4.33e-07 GO:0045184 establishment of protein localization
1.62 5.80e-07 GO:0070647 protein modification by small protein conjugation or removal
1.65 6.28e-07 GO:0008380 RNA splicing
1.99 1.60e-06 GO:0042254 ribosome biogenesis
1.34 2.90e-06 GO:0032774 RNA biosynthetic process
2.08 3.68e-06 GO:0006414 translational elongation
1.77 4.18e-06 GO:0022613 ribonucleoprotein complex biogenesis
1.66 5.75e-06 GO:0016567 protein ubiquitination
1.31 7.55e-06 GO:0008104 protein localization
1.63 7.90e-06 GO:0032446 protein modification by small protein conjugation
1.30 8.60e-06 GO:0044248 cellular catabolic process
1.59 1.13e-05 GO:0051325 interphase
1.16 1.42e-05 GO:0060255 regulation of macromolecule metabolic process
1.45 1.66e-05 GO:0006974 response to DNA damage stimulus
1.71 1.89e-05 GO:0071843 cellular component biogenesis at cellular level
1.72 2.20e-05 GO:0000375 RNA splicing, via transesterification reactions
1.37 2.43e-05 GO:0016192 vesicle-mediated transport
1.73 2.57e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.73 2.57e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
1.58 2.86e-05 GO:0051329 interphase of mitotic cell cycle
1.19 3.08e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.96 5.27e-05 GO:0032984 macromolecular complex disassembly
1.96 5.27e-05 GO:0034623 cellular macromolecular complex disassembly
1.34 5.92e-05 GO:0033554 cellular response to stress
1.66 6.21e-05 GO:0071156 regulation of cell cycle arrest
1.27 7.21e-05 GO:0051641 cellular localization
1.29 8.44e-05 GO:0051649 establishment of localization in cell
2.05 1.05e-04 GO:0006415 translational termination
1.18 1.30e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.76 1.37e-04 GO:0010498 proteasomal protein catabolic process
1.76 1.37e-04 GO:0022415 viral reproductive process
1.76 1.37e-04 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.66 1.57e-04 GO:0000075 cell cycle checkpoint
1.97 2.19e-04 GO:0043241 protein complex disassembly
1.97 2.19e-04 GO:0043624 cellular protein complex disassembly
1.81 2.90e-04 GO:0019058 viral infectious cycle
1.27 2.94e-04 GO:0044085 cellular component biogenesis
1.47 2.95e-04 GO:0006886 intracellular protein transport
1.45 3.44e-04 GO:0000279 M phase
1.67 4.99e-04 GO:0022411 cellular component disassembly
1.67 4.99e-04 GO:0071845 cellular component disassembly at cellular level
1.40 6.51e-04 GO:0070727 cellular macromolecule localization
1.99 9.03e-04 GO:0019080 viral genome expression
1.99 9.03e-04 GO:0019083 viral transcription
1.48 9.94e-04 GO:0051301 cell division
1.40 1.03e-03 GO:0034621 cellular macromolecular complex subunit organization
1.52 1.10e-03 GO:0006366 transcription from RNA polymerase II promoter
1.39 1.11e-03 GO:0034613 cellular protein localization
1.16 1.37e-03 GO:0010468 regulation of gene expression
2.03 1.43e-03 GO:0006353 transcription termination, DNA-dependent
1.13 1.54e-03 GO:0031323 regulation of cellular metabolic process
1.35 1.57e-03 GO:0051726 regulation of cell cycle
1.13 1.68e-03 GO:0080090 regulation of primary metabolic process
1.78 1.99e-03 GO:0007093 mitotic cell cycle checkpoint
1.29 2.93e-03 GO:0043933 macromolecular complex subunit organization
1.72 3.19e-03 GO:0000082 G1/S transition of mitotic cell cycle
1.51 3.87e-03 GO:0010608 posttranscriptional regulation of gene expression
1.45 4.03e-03 GO:0010564 regulation of cell cycle process
1.17 4.90e-03 GO:0051252 regulation of RNA metabolic process
1.77 5.21e-03 GO:0031018 endocrine pancreas development
1.31 6.35e-03 GO:0006915 apoptosis
1.74 6.37e-03 GO:0006403 RNA localization
1.12 7.12e-03 GO:0019222 regulation of metabolic process
1.28 7.27e-03 GO:0016265 death
1.34 7.68e-03 GO:0071822 protein complex subunit organization
1.80 8.57e-03 GO:0007059 chromosome segregation
1.27 9.74e-03 GO:0008219 cell death
1.15 9.86e-03 GO:0009889 regulation of biosynthetic process
1.30 1.00e-02 GO:0012501 programmed cell death
1.74 1.03e-02 GO:0050657 nucleic acid transport
1.74 1.03e-02 GO:0050658 RNA transport
1.74 1.03e-02 GO:0051236 establishment of RNA localization
1.14 1.05e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.77 1.07e-02 GO:0051320 S phase
1.21 1.14e-02 GO:0009056 catabolic process
1.15 1.30e-02 GO:0031326 regulation of cellular biosynthetic process
1.88 1.65e-02 GO:0051168 nuclear export
1.33 1.66e-02 GO:0006259 DNA metabolic process
1.37 1.96e-02 GO:0016044 cellular membrane organization
1.88 2.11e-02 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.84 2.23e-02 GO:0006364 rRNA processing
1.91 2.26e-02 GO:0031123 RNA 3'-end processing
1.86 2.46e-02 GO:0000236 mitotic prometaphase
1.16 2.67e-02 GO:0006355 regulation of transcription, DNA-dependent
1.37 2.68e-02 GO:0061024 membrane organization
1.88 2.69e-02 GO:0031575 mitotic cell cycle G1/S transition checkpoint
1.88 2.69e-02 GO:0071779 G1/S transition checkpoint
1.26 2.77e-02 GO:0006351 transcription, DNA-dependent
1.98 3.12e-02 GO:0031124 mRNA 3'-end processing
1.73 3.42e-02 GO:0000084 S phase of mitotic cell cycle
1.73 3.42e-02 GO:0051028 mRNA transport
1.88 4.37e-02 GO:0000209 protein polyubiquitination
1.46 4.61e-02 GO:0034660 ncRNA metabolic process
1.84 4.64e-02 GO:0051351 positive regulation of ligase activity
1.84 4.64e-02 GO:2000045 regulation of G1/S transition of mitotic cell cycle

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 2.02e-49 GO:0044424 intracellular part
1.14 3.96e-48 GO:0005622 intracellular
1.19 1.11e-45 GO:0043231 intracellular membrane-bounded organelle
1.19 1.40e-45 GO:0043227 membrane-bounded organelle
1.17 9.32e-45 GO:0043229 intracellular organelle
1.17 1.78e-44 GO:0043226 organelle
1.27 3.00e-40 GO:0005634 nucleus
1.39 2.47e-27 GO:0031974 membrane-enclosed lumen
1.39 1.29e-26 GO:0043233 organelle lumen
1.38 1.03e-25 GO:0070013 intracellular organelle lumen
1.39 3.06e-25 GO:0044428 nuclear part
1.20 2.49e-23 GO:0044446 intracellular organelle part
1.20 6.69e-23 GO:0044422 organelle part
1.39 3.53e-21 GO:0031981 nuclear lumen
1.13 3.44e-19 GO:0005737 cytoplasm
1.72 8.13e-18 GO:0030529 ribonucleoprotein complex
1.27 1.31e-15 GO:0043228 non-membrane-bounded organelle
1.27 1.31e-15 GO:0043232 intracellular non-membrane-bounded organelle
1.16 6.55e-15 GO:0044444 cytoplasmic part
1.64 8.79e-14 GO:0005730 nucleolus
1.22 1.32e-13 GO:0032991 macromolecular complex
1.28 4.24e-12 GO:0005829 cytosol
1.33 3.27e-10 GO:0005654 nucleoplasm
1.03 2.66e-07 GO:0044464 cell part
1.03 2.89e-07 GO:0005623 cell
1.91 2.90e-07 GO:0000793 condensed chromosome
1.74 2.73e-06 GO:0005840 ribosome
1.43 2.76e-06 GO:0005694 chromosome
1.88 3.33e-06 GO:0005681 spliceosomal complex
2.13 1.81e-05 GO:0022626 cytosolic ribosome
1.15 7.77e-05 GO:0043234 protein complex
1.74 2.12e-04 GO:0000151 ubiquitin ligase complex
1.94 2.25e-04 GO:0000776 kinetochore
1.69 4.04e-04 GO:0044445 cytosolic part
1.98 4.74e-04 GO:0000779 condensed chromosome, centromeric region
2.01 4.75e-04 GO:0000777 condensed chromosome kinetochore
1.95 7.45e-04 GO:0071013 catalytic step 2 spliceosome
1.69 7.63e-04 GO:0000775 chromosome, centromeric region
2.48 7.97e-04 GO:0022627 cytosolic small ribosomal subunit
1.38 1.15e-03 GO:0044427 chromosomal part
2.15 1.32e-03 GO:0015935 small ribosomal subunit
1.48 1.12e-02 GO:0016604 nuclear body
1.65 1.36e-02 GO:0016607 nuclear speck
1.26 1.47e-02 GO:0044451 nucleoplasm part
1.89 1.88e-02 GO:0030117 membrane coat
1.89 1.88e-02 GO:0048475 coated membrane
2.16 2.35e-02 GO:0030120 vesicle coat
1.37 3.88e-02 GO:0005815 microtubule organizing center

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.61 5.83e-21 GO:0003723 RNA binding
1.15 3.60e-20 GO:0005515 protein binding
1.08 9.33e-18 GO:0005488 binding
1.25 3.30e-17 GO:0003676 nucleic acid binding
1.81 1.14e-05 GO:0003735 structural constituent of ribosome
1.99 3.10e-04 GO:0008135 translation factor activity, nucleic acid binding
1.17 4.66e-04 GO:0000166 nucleotide binding
1.38 1.16e-02 GO:0000988 protein binding transcription factor activity
1.38 1.16e-02 GO:0000989 transcription factor binding transcription factor activity
1.50 1.23e-02 GO:0003713 transcription coactivator activity
1.15 1.50e-02 GO:0008270 zinc ion binding
1.37 1.62e-02 GO:0003712 transcription cofactor activity
1.62 1.76e-02 GO:0004386 helicase activity
1.49 1.87e-02 GO:0004842 ubiquitin-protein ligase activity
1.47 2.31e-02 GO:0019787 small conjugating protein ligase activity
1.14 3.27e-02 GO:0003677 DNA binding
1.08 4.38e-02 GO:0003824 catalytic activity
1.68 4.88e-02 GO:0008026 ATP-dependent helicase activity
1.68 4.88e-02 GO:0070035 purine NTP-dependent helicase activity