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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: EWSR1-FLI1.p2

Z-value: 1.100

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_93030538	3.273	NM_005665	EVI5	ecotropic viral integration site 5
chr3_-_50353209	2.041	NM_007182 NM_170714	RASSF1	Ras association (RalGDS/AF-6) domain family member 1
chrX_+_1361570	1.930	NM_001161530 NM_172247	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr1_+_165865953	1.440	NM_052862	RCSD1	RCSD domain containing 1
chr19_-_55763091	1.399	NM_001080457	LRRC4B	leucine rich repeat containing 4B
chr5_-_71838875	1.342	NM_152625	ZNF366	zinc finger protein 366
chr1_-_31003181	1.273		LAPTM5	lysosomal protein transmembrane 5
chr1_+_246087230	1.228		TRIM58	tripartite motif containing 58
chr8_-_38127489	1.173	NM_000349	STAR	steroidogenic acute regulatory protein
chr1_+_246087104	1.157	NM_015431	TRIM58	tripartite motif containing 58
chr10_+_83627422	1.137	NM_001165973	NRG3	neuregulin 3
chr1_-_31003260	1.069	NM_006762	LAPTM5	lysosomal protein transmembrane 5
chr12_+_84198015	1.042	NM_006982	ALX1	ALX homeobox 1
chr2_-_99284070	0.971	NM_174898	LYG1	lysozyme G-like 1
chrX_-_78509662	0.946	NM_001171581 NM_004867	ITM2A	integral membrane protein 2A
chr1_+_185064654	0.941	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr17_+_45706786	0.927	NM_153229	TMEM92	transmembrane protein 92
chr13_-_32678142	0.903	NM_052851	STARD13	StAR-related lipid transfer (START) domain containing 13
chr1_+_165866127	0.893		RCSD1	RCSD domain containing 1
chr11_+_73034870	0.825	NM_001130033 NM_021200	PLEKHB1	pleckstrin homology domain containing, family B (evectins) member 1
chr11_+_63730766	0.800		FERMT3	fermitin family member 3
chrX_-_78509367	0.794		ITM2A	integral membrane protein 2A
chr18_-_5620629	0.738		EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr18_+_41659542	0.731	NM_213602	SIGLEC15	sialic acid binding Ig-like lectin 15
chr8_-_93176819	0.719		RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_145671947	0.709		FOXH1	forkhead box H1
chr20_-_48741481	0.700
chr3_-_193609531	0.672	NM_021032	FGF12	fibroblast growth factor 12
chr11_+_10434056	0.653	NM_001025390	AMPD3	adenosine monophosphate deaminase 3
chr19_-_44060729	0.646	NM_001195833 NM_198445	RINL	Ras and Rab interactor-like
chrX_+_48529905	0.623	NM_002049	GATA1	GATA binding protein 1 (globin transcription factor 1)
chr8_-_93177057	0.611	NM_001198625 NM_001198626 NM_001198627 NM_001198631 NM_001198634 NM_001198679	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_231498081	0.566	NM_014801	PCNXL2	pecanex-like 2 (Drosophila)
chr7_-_75256999	0.562	NM_006072	CCL26	chemokine (C-C motif) ligand 26
chr8_-_145672525	0.551	NM_003923	FOXH1	forkhead box H1
chr19_-_9098625	0.547	NM_001001958	OR7G3	olfactory receptor, family 7, subfamily G, member 3
chr12_+_64869271	0.547		IRAK3	interleukin-1 receptor-associated kinase 3
chr12_+_10222823	0.545	NM_153022	C12orf59	chromosome 12 open reading frame 59
chr19_-_4867814	0.542
chrX_+_138060	0.536	NM_018390	PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1
chr11_+_10433241	0.531	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr12_+_64869296	0.524		IRAK3	interleukin-1 receptor-associated kinase 3
chr21_+_39099624	0.524		ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr4_-_57216816	0.506		HOPX	HOP homeobox
chr15_-_77085056	0.483	NM_153815	RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1
chr7_-_99604127	0.481		GAL3ST4	galactose-3-O-sulfotransferase 4
chr1_+_12627152	0.476	NM_001013630	AADACL4	arylacetamide deacetylase-like 4
chr7_-_127458231	0.474	NM_022143	LRRC4	leucine rich repeat containing 4
chr19_+_13066956	0.472		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr4_-_16509354	0.467		LDB2	LIM domain binding 2
chr1_-_171442937	0.465	NM_003326	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr4_-_16509126	0.463		LDB2	LIM domain binding 2
chr6_+_117044334	0.453	NM_001010892 NM_001161664	RSPH4A	radial spoke head 4 homolog A (Chlamydomonas)
chr11_+_63730720	0.440	NM_031471 NM_178443	FERMT3	fermitin family member 3
chrX_-_49851743	0.435	NM_139289	AKAP4	A kinase (PRKA) anchor protein 4
chrX_+_107569671	0.431	NM_000495 NM_033380	COL4A5	collagen, type IV, alpha 5
chr7_+_24290331	0.422	NM_000905	NPY	neuropeptide Y
chr10_+_114700775	0.418		TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr4_-_16509446	0.418	NM_001130834 NM_001290	LDB2	LIM domain binding 2
chr1_-_21478571	0.401	NM_001113347	ECE1	endothelin converting enzyme 1
chr12_+_64869181	0.393	NM_001142523 NM_007199	IRAK3	interleukin-1 receptor-associated kinase 3
chr9_+_134843918	0.393	NM_001135031 NM_004188	GFI1B	growth factor independent 1B transcription repressor
chr16_-_79811475	0.389	NM_001076780 NM_052892	PKD1L2	polycystic kidney disease 1-like 2
chrX_-_131918905	0.380		HS6ST2	heparan sulfate 6-O-sulfotransferase 2
chrX_-_109447970	0.377	NM_001025580 NM_015365	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr7_-_99604171	0.376	NM_024637	GAL3ST4	galactose-3-O-sulfotransferase 4
chr19_-_18220009	0.374	NM_000923	PDE4C	phosphodiesterase 4C, cAMP-specific
chr19_-_44518465	0.361		GMFG	glia maturation factor, gamma
chr11_-_76800525	0.361		PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr12_-_92489652	0.359		LOC144481	hypothetical protein LOC144481
chr14_-_63079492	0.358		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr14_-_63079299	0.355		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr21_+_39099717	0.354	NM_005239	ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr16_-_74126568	0.353	NM_024533	CHST5	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr3_+_77171938	0.352	NM_002942	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr15_-_56829069	0.342		ADAM10	ADAM metallopeptidase domain 10
chr5_+_175041069	0.336	NM_022304	HRH2	histamine receptor H2
chr1_-_87152596	0.334	NM_004261 NM_203341	SEP15	15 kDa selenoprotein
chr17_+_27288253	0.334		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr1_+_109969571	0.323	NM_203404	AMPD2	adenosine monophosphate deaminase 2
chr5_-_64100176	0.319		SREK1IP1	SREK1-interacting protein 1
chr4_-_57217226	0.316	NM_001145459 NM_139211	HOPX	HOP homeobox
chr11_+_58668827	0.315	NM_022074 NM_198847	FAM111A	family with sequence similarity 111, member A
chr1_-_6468600	0.310	NM_001042665	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr10_-_103864651	0.307	NM_003893	LDB1	LIM domain binding 1
chr19_-_44518516	0.307	NM_004877	GMFG	glia maturation factor, gamma
chr3_-_15875932	0.302	NM_015199	ANKRD28	ankyrin repeat domain 28
chr1_+_221955876	0.302	NM_001146068	CAPN2	calpain 2, (m/II) large subunit
chr5_-_64100239	0.301	NM_173829	SREK1IP1	SREK1-interacting protein 1
chrX_-_109447954	0.301		AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_+_26895108	0.295	NM_006015 NM_139135	ARID1A	AT rich interactive domain 1A (SWI-like)
chr10_+_104211134	0.291		TMEM180	transmembrane protein 180
chr2_-_96167900	0.290	NM_001002036	ASTL	astacin-like metallo-endopeptidase (M12 family)
chr7_-_106991941	0.285	NM_001161520 NM_006348 NM_181733	COG5	component of oligomeric golgi complex 5
chr19_+_54621499	0.282	NM_001195256	LOC645971	hypothetical protein LOC645971
chr11_-_62231358	0.279		BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_-_68071635	0.275	NM_018841	GNG12	guanine nucleotide binding protein (G protein), gamma 12
chr10_+_104211148	0.274	NM_024789	TMEM180	transmembrane protein 180
chr5_-_81082699	0.274	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr3_+_171558215	0.273		SKIL	SKI-like oncogene
chr3_+_171558188	0.270		SKIL	SKI-like oncogene
chr4_+_120029426	0.267	NM_001128933 NM_001128934 NM_133477	SYNPO2	synaptopodin 2
chr12_-_47637396	0.267		ARF3	ADP-ribosylation factor 3
chr8_-_93176618	0.261	NM_001198629 NM_001198630 NM_001198632 NM_175635	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_+_71605466	0.258	NM_000803 NM_001113534 NM_001113535 NM_001113536	FOLR2	folate receptor 2 (fetal)
chrX_-_109448083	0.256		AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr10_-_35143900	0.253	NM_001184785 NM_001184786 NM_001184787 NM_001184788 NM_001184789 NM_001184790 NM_001184791 NM_001184792 NM_001184793 NM_001184794 NM_019619	PARD3	par-3 partitioning defective 3 homolog (C. elegans)
chr1_-_150276064	0.252		S100A11	S100 calcium binding protein A11
chr20_+_10147455	0.247	NM_003081 NM_130811	SNAP25	synaptosomal-associated protein, 25kDa
chr15_+_39310757	0.246		CHP	calcium binding protein P22
chrX_-_152844880	0.246		ARHGAP4	Rho GTPase activating protein 4
chr4_+_151218862	0.244	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr1_-_224563461	0.241		LIN9	lin-9 homolog (C. elegans)
chrX_-_108611940	0.238	NM_001522	GUCY2F	guanylate cyclase 2F, retinal
chr12_-_107238568	0.237	NM_001142345	CMKLR1	chemokine-like receptor 1
chr15_-_56829104	0.237		ADAM10	ADAM metallopeptidase domain 10
chr14_-_99016833	0.235		SETD3	SET domain containing 3
chr5_+_137701855	0.234		FAM53C	family with sequence similarity 53, member C
chr5_-_38631263	0.233	NM_002310	LIFR	leukemia inhibitory factor receptor alpha
chr12_-_54869511	0.230		SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr19_-_51820133	0.229	NM_000960	PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)
chr1_+_242691295	0.227	NM_001130957 NM_173807	C1orf101	chromosome 1 open reading frame 101
chr15_+_39310693	0.227	NM_007236	CHP	calcium binding protein P22
chr1_-_109957195	0.223	NM_005272	GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr17_+_27288152	0.222	NM_015355	SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr7_+_128142661	0.222	NM_032599	FAM71F1	family with sequence similarity 71, member F1
chr11_+_2279932	0.221		TSPAN32	tetraspanin 32
chr1_-_150276114	0.221	NM_005620	S100A11	S100 calcium binding protein A11
chr14_+_59782222	0.219	NM_177952	PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr7_+_21434818	0.219
chr15_+_89248423	0.218	NM_006122	MAN2A2	mannosidase, alpha, class 2A, member 2
chr12_-_47637530	0.214
chr14_-_63079724	0.212		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr1_-_150276091	0.212		S100A11	S100 calcium binding protein A11
chr15_-_66285427	0.212	NM_001031733 NM_033429	CALML4	calmodulin-like 4
chr1_+_87153025	0.208		HS2ST1	heparan sulfate 2-O-sulfotransferase 1
chr1_+_160868932	0.208		DDR2	discoidin domain receptor tyrosine kinase 2
chr5_+_137701852	0.208		FAM53C	family with sequence similarity 53, member C
chr14_-_63079816	0.207	NM_006246	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr12_-_47637564	0.203		ARF3	ADP-ribosylation factor 3
chr3_-_129852345	0.201		RPN1	ribophorin I
chr1_+_157441133	0.201	NM_002036	DARC	Duffy blood group, chemokine receptor
chr1_+_160868822	0.195	NM_001014796 NM_006182	DDR2	discoidin domain receptor tyrosine kinase 2
chr12_-_47637507	0.193		ARF3	ADP-ribosylation factor 3
chr17_-_8004671	0.193		VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr10_-_103864579	0.193		LDB1	LIM domain binding 1
chr19_-_57592778	0.191		LOC284373	hypothetical protein LOC284373
chr17_+_2443652	0.188	NM_000430	PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr3_-_129852400	0.187	NM_002950	RPN1	ribophorin I
chr12_-_47637518	0.185	NM_001659	ARF3	ADP-ribosylation factor 3
chr12_-_47637512	0.184		ARF3	ADP-ribosylation factor 3
chr11_-_62231445	0.183		BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr8_-_37943143	0.182	NM_000025	ADRB3	adrenergic, beta-3-, receptor
chr11_+_10480891	0.182		AMPD3	adenosine monophosphate deaminase 3
chr5_+_137701601	0.181	NM_016605	FAM53C	family with sequence similarity 53, member C
chr11_+_2279812	0.180	NM_139022	TSPAN32	tetraspanin 32
chr12_+_105501161	0.180	NM_213594	RFX4	regulatory factor X, 4 (influences HLA class II expression)
chrX_-_102870207	0.178	NM_001024452 NM_001172285	GLRA4	glycine receptor, alpha 4
chr11_-_62231636	0.178	NM_001122955	BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_-_62231386	0.177		BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr18_+_75388522	0.177		NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr17_+_27288167	0.176		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr12_+_52060191	0.175	NM_138473	SP1	Sp1 transcription factor
chr2_+_113533155	0.172	NM_012275	IL1F5	interleukin 1 family, member 5 (delta)
chr19_+_57592913	0.169	NM_032423	ZNF528	zinc finger protein 528
chrX_+_24077649	0.168	NM_001178086 NM_001178095 NM_001178084 NM_001178085 NM_003410	ZFX	zinc finger protein, X-linked
chr17_+_27288178	0.167		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr7_+_49783774	0.165	NM_198570	VWC2	von Willebrand factor C domain containing 2
chr1_+_28936030	0.164	NM_001172828	YTHDF2	YTH domain family, member 2
chr11_-_67163600	0.162	NM_005995	TBX10	T-box 10
chr11_-_2279642	0.161	NM_001142946	C11orf21	chromosome 11 open reading frame 21
chr1_+_157441824	0.161	NM_001122951	DARC	Duffy blood group, chemokine receptor
chr1_-_184684478	0.159	NM_022576	PDC	phosducin
chr3_-_193928038	0.159	NM_004113	FGF12	fibroblast growth factor 12
chr18_+_54682261	0.159		ZNF532	zinc finger protein 532
chrX_+_56606686	0.158	NM_013444	UBQLN2	ubiquilin 2
chr5_+_150020595	0.156	NM_001122853 NM_133371	MYOZ3	myozenin 3
chr17_+_24598000	0.156	NM_005208	CRYBA1	crystallin, beta A1
chrX_+_67635348	0.156	NM_001195214 NM_173834	YIPF6	Yip1 domain family, member 6
chr8_-_133562185	0.156	NM_004519	KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3
chr17_+_27288374	0.155
chr9_-_138701721	0.154	NM_001012727 NM_006412	AGPAT2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr4_-_96689137	0.154		UNC5C	unc-5 homolog C (C. elegans)
chr11_-_117628211	0.153	NM_198275	MPZL3	myelin protein zero-like 3
chr15_+_81906983	0.152	NM_003027	SH3GL3	SH3-domain GRB2-like 3
chr9_+_35528628	0.151	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr6_-_130578110	0.149	NM_152552	SAMD3	sterile alpha motif domain containing 3
chr1_+_153241665	0.148	NM_015872	ZBTB7B	zinc finger and BTB domain containing 7B
chr7_+_128218685	0.147		CCDC136	coiled-coil domain containing 136
chr5_+_156819782	0.146		NIPAL4	NIPA-like domain containing 4
chr1_-_155936904	0.146	NM_052939	FCRL3	Fc receptor-like 3
chr9_+_35528890	0.144		RUSC2	RUN and SH3 domain containing 2
chr12_+_88627601	0.144		LOC338758	hypothetical LOC338758
chr21_+_38550533	0.144	NM_002243	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_44185005	0.143	NM_014652	IPO13	importin 13
chr14_-_63079840	0.142		PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr19_+_54883732	0.142	NM_001101340	C19orf76	chromosome 19 open reading frame 76
chr12_-_40824699	0.142	NM_001099650 NM_173601	GXYLT1	glucoside xylosyltransferase 1
chr1_+_87152905	0.139	NM_001134492 NM_012262	HS2ST1	heparan sulfate 2-O-sulfotransferase 1
chr2_+_182464910	0.137		SSFA2	sperm specific antigen 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.73	9.54e-04	GO:0048518	positive regulation of biological process
1.59	1.27e-03	GO:0023052	signaling
2.62	1.04e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.70	1.12e-02	GO:0048522	positive regulation of cellular process
2.79	1.25e-02	GO:0048858	cell projection morphogenesis
2.59	1.30e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
2.77	1.44e-02	GO:0032990	cell part morphogenesis
2.57	1.47e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.93	1.73e-02	GO:0007399	nervous system development
2.87	2.03e-02	GO:0048812	neuron projection morphogenesis
1.91	2.30e-02	GO:0009653	anatomical structure morphogenesis
1.78	2.79e-02	GO:0048583	regulation of response to stimulus
2.73	2.85e-02	GO:0031175	neuron projection development
2.64	3.01e-02	GO:0045892	negative regulation of transcription, DNA-dependent
2.88	3.04e-02	GO:0007409	axonogenesis
2.28	3.05e-02	GO:0048584	positive regulation of response to stimulus
2.46	3.19e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
2.59	4.15e-02	GO:0051253	negative regulation of RNA metabolic process

Nothing significant found in compartment category.

Nothing significant found in function category.