Motif ID: FOS_FOS{B,L1}_JUN{B,D}.p2

Z-value: 5.101


Transcription factors associated with FOS_FOS{B,L1}_JUN{B,D}.p2:

Gene SymbolEntrez IDGene Name
FOS 2353 v-fos FBJ murine osteosarcoma viral oncogene homolog
FOSB 2354 FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 8061 FOS-like antigen 1
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOSL1chr11_-_65424434-0.837.6e-05Click!
JUNDchr19_-_18253436-0.562.5e-02Click!
JUNBchr19_+_12763295-0.514.3e-02Click!
FOSBchr19_+_506630890.185.1e-01Click!
FOSchr14_+_748152330.039.1e-01Click!


Activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2.

activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2


Sorted Z-values histogram for motif FOS_FOS{B,L1}_JUN{B,D}.p2

Sorted Z-values for motif FOS_FOS{B,L1}_JUN{B,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOS_FOS{B,L1}_JUN{B,D}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_221955876 30.697 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr18_+_19706979 22.081 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr1_-_177378801 21.255 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr1_-_115682374 20.028 NM_002506
NGF
nerve growth factor (beta polypeptide)
chr18_+_59593591 19.433 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr21_+_29439768 18.760 C21orf7
chromosome 21 open reading frame 7
chr3_+_11153778 18.222 NM_001098213
HRH1
histamine receptor H1
chr17_-_37022465 17.887 NM_005557
KRT16
keratin 16
chr9_-_90456824 15.123 NM_001100111
LOC286238
hypothetical protein LOC286238
chr10_-_88720908 14.991 LOC100133190
hypothetical LOC100133190
chr20_-_17487480 14.718 NM_001161705
BFSP1
beaded filament structural protein 1, filensin
chr15_-_53996597 14.276 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr5_+_150000394 14.102 NM_001109974
NM_007286
SYNPO

synaptopodin

chr13_+_77007809 13.551 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr5_+_145297490 13.173 SH3RF2
SH3 domain containing ring finger 2
chr12_-_51173238 12.735 NM_005554
KRT6A
keratin 6A
chr17_-_36996611 12.729 NM_000526
KRT14
keratin 14
chr1_-_36589744 12.542


chr10_+_24795465 12.263 KIAA1217
KIAA1217
chr14_-_104507862 12.107 AHNAK2
AHNAK nucleoprotein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
9.05 5.71e-03 GO:0031581 hemidesmosome assembly
8.13 3.20e-03 GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein
2.40 9.24e-03 GO:0008544 epidermis development
2.32 3.57e-02 GO:0007517 muscle organ development
2.20 5.76e-03 GO:0061061 muscle structure development
1.78 5.26e-05 GO:0009888 tissue development
1.60 1.14e-02 GO:0009611 response to wounding
1.59 8.68e-03 GO:0042127 regulation of cell proliferation
1.40 9.11e-03 GO:0048513 organ development
1.36 5.01e-04 GO:0048731 system development
1.35 1.62e-04 GO:0048856 anatomical structure development
1.30 1.81e-03 GO:0007165 signal transduction
1.30 1.90e-03 GO:0007275 multicellular organismal development
1.29 8.60e-04 GO:0032502 developmental process
1.27 6.23e-03 GO:0023052 signaling

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
5.42 2.00e-02 GO:0001533 cornified envelope
1.87 4.02e-02 GO:0005578 proteinaceous extracellular matrix
1.52 4.75e-03 GO:0044421 extracellular region part
1.38 9.55e-04 GO:0005576 extracellular region
1.38 1.59e-02 GO:0005856 cytoskeleton
1.31 2.03e-02 GO:0044459 plasma membrane part
1.24 1.76e-03 GO:0005886 plasma membrane
1.23 3.55e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.14 2.16e-02 GO:0005515 protein binding