Motif ID: FOXA2.p3

Z-value: 3.261


Transcription factors associated with FOXA2.p3:

Gene SymbolEntrez IDGene Name
FOXA2 3170 forkhead box A2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXA2chr20_-_225140920.741.1e-03Click!


Activity profile for motif FOXA2.p3.

activity profile for motif FOXA2.p3


Sorted Z-values histogram for motif FOXA2.p3

Sorted Z-values for motif FOXA2.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA2.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_69716298 9.253 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr6_+_131190237 9.114 NM_001195597
LOC285733
hypothetical LOC285733
chr3_-_71376919 9.059 FOXP1
forkhead box P1
chr6_-_41823056 8.106 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr5_+_147754467 7.551 FBXO38
F-box protein 38
chr2_+_113601616 7.370 IL1RN
interleukin 1 receptor antagonist
chr1_-_176205672 7.340 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr3_-_150422474 6.783 NM_000096
CP
ceruloplasmin (ferroxidase)
chr2_+_113601608 6.696 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr1_-_57204208 6.636 NM_000066
C8B
complement component 8, beta polypeptide
chr17_+_50699965 6.188 HLF
hepatic leukemia factor
chr12_+_27740694 6.131 NM_001029874
REP15
RAB15 effector protein
chr4_+_6746466 6.052 NM_005980
S100P
S100 calcium binding protein P
chr22_+_19458378 5.993 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr12_+_119900931 5.827 NM_000545
HNF1A
HNF1 homeobox A
chr2_-_165133239 5.817 GRB14
growth factor receptor-bound protein 14
chr22_+_33792125 5.718 NM_001008494
ISX
intestine-specific homeobox
chr17_-_43390108 5.702 NM_024320
PRR15L
proline rich 15-like
chr6_-_31953425 5.652 NM_001178045
SLC44A4
solute carrier family 44, member 4
chr1_-_229627412 5.643 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr2_-_233586164 5.640 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr12_+_119900677 5.403 HNF1A
HNF1 homeobox A
chr5_+_132237253 5.394 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr2_-_233586145 5.380 NGEF
neuronal guanine nucleotide exchange factor
chr11_-_34491878 5.273 NM_001422
ELF5
E74-like factor 5 (ets domain transcription factor)
chr15_+_64661560 5.238


chrX_-_55037235 5.208 NM_002625
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr10_+_102722275 5.189 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr17_-_23721351 4.828 VTN
vitronectin
chr17_-_23721430 4.796 VTN
vitronectin
chr14_-_22358752 4.720 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr16_-_86527608 4.541 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr20_+_31334601 4.482 NM_033197
C20orf114
chromosome 20 open reading frame 114
chr6_+_112481970 4.462 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr8_-_30121741 4.451 NM_001100916
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr6_-_26038817 4.392 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr4_+_187385618 4.390 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr10_-_54201400 4.292 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr7_+_94953148 4.281 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr3_+_152970904 4.279 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr7_+_116238309 4.202 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr12_-_51629874 4.194 KRT8
keratin 8
chr1_-_176205970 4.182 SEC16B
SEC16 homolog B (S. cerevisiae)
chr18_+_27425727 4.149 NM_000371
TTR
transthyretin
chr20_-_52120421 4.079 BCAS1
breast carcinoma amplified sequence 1
chr6_+_32003180 4.073 NM_000063
NM_001145903
C2

complement component 2

chr1_+_16203317 4.021 NM_178840
C1orf64
chromosome 1 open reading frame 64
chr2_-_32344192 3.970 NM_021209
NLRC4
NLR family, CARD domain containing 4
chr7_-_50596238 3.949 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr17_+_69939130 3.936 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr21_-_42608531 3.929 TFF3
trefoil factor 3 (intestinal)
chr17_-_23721420 3.924 VTN
vitronectin
chr9_-_14900992 3.919 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chr17_+_9686572 3.916 GLP2R
glucagon-like peptide 2 receptor
chr4_+_39084936 3.760 KLB
klotho beta
chr9_+_135277264 3.758 ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr12_+_99391681 3.756 NM_005123
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr9_+_135276940 3.754 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr3_+_187813553 3.740 AHSG
alpha-2-HS-glycoprotein
chr17_-_23721468 3.731 VTN
vitronectin
chr11_+_22652894 3.670 NM_005256
GAS2
growth arrest-specific 2
chr17_-_61655915 3.645 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr14_+_87560646 3.643 LOC283587
hypothetical protein LOC283587
chr14_+_20226762 3.635 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr12_+_99391870 3.594 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr1_-_177106702 3.581 NM_004673
ANGPTL1
angiopoietin-like 1
chr3_-_121884091 3.573 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr1_-_205272619 3.558 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr3_-_121883647 3.520 HGD
homogentisate 1,2-dioxygenase
chr11_-_6418705 3.494 NM_000613
HPX
hemopexin
chr14_-_106282128 3.478 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_+_139245197 3.478 NM_080877
SLC34A3
solute carrier family 34 (sodium phosphate), member 3
chr1_-_167822248 3.458 F5
coagulation factor V (proaccelerin, labile factor)
chr12_-_119249938 3.419 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr1_-_167822334 3.406 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chr2_+_132196533 3.310 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr17_-_23721485 3.309 NM_000638
VTN
vitronectin
chr11_-_116168316 3.292 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr3_+_173043832 3.261 NM_001164436
TMEM212
transmembrane protein 212
chr11_+_22652957 3.235 GAS2
growth arrest-specific 2
chr4_+_39084867 3.229 NM_175737
KLB
klotho beta
chr17_+_64922420 3.157 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr10_+_7785360 3.107 ITIH2
inter-alpha (globulin) inhibitor H2
chr1_-_1346465 3.082 NM_001145210
LOC441869
hypothetical protein LOC441869
chr17_-_6958695 3.031 ASGR2
asialoglycoprotein receptor 2
chr14_-_69333624 3.026 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr3_+_187813538 3.022 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr10_+_7785347 3.017 ITIH2
inter-alpha (globulin) inhibitor H2
chr12_-_69837831 3.008 TSPAN8
tetraspanin 8
chr5_+_27508139 2.987 LOC643401
hypothetical protein LOC643401
chr10_+_7785235 2.983 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr19_-_63715135 2.971 NM_012254
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr1_-_20179495 2.950 NM_000300
NM_001161727
NM_001161728
PLA2G2A


phospholipase A2, group IIA (platelets, synovial fluid)


chr12_-_101835026 2.923 PAH
phenylalanine hydroxylase
chr9_+_139245029 2.912 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr7_+_100037817 2.895 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr2_-_21084077 2.870 APOB
apolipoprotein B (including Ag(x) antigen)
chr10_+_7785290 2.848 ITIH2
inter-alpha (globulin) inhibitor H2
chr14_-_93859394 2.842 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr17_+_38259620 2.838 AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr10_+_101532544 2.751 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr10_+_114144512 2.749 ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_148496792 2.738 NM_012113
CA14
carbonic anhydrase XIV
chr8_+_18072250 2.726 NM_001160179
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr4_+_187424336 2.695 F11
coagulation factor XI
chr22_-_37044034 2.679 NM_001894
CSNK1E
casein kinase 1, epsilon
chr3_-_150569574 2.678 TM4SF1
transmembrane 4 L six family member 1
chr17_-_36418869 2.667 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr20_+_41621079 2.650 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr10_+_7785331 2.644 ITIH2
inter-alpha (globulin) inhibitor H2
chr12_-_9159742 2.638 A2M
alpha-2-macroglobulin
chr2_-_135498716 2.625 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr2_+_11591692 2.605 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr12_-_9159780 2.578 A2M
alpha-2-macroglobulin
chr20_-_52120710 2.564 NM_003657
BCAS1
breast carcinoma amplified sequence 1
chr12_-_9159707 2.552 A2M
alpha-2-macroglobulin
chr21_-_42659671 2.536 NM_003225
TFF1
trefoil factor 1
chr1_+_54132447 2.518 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr12_-_69838045 2.495 NM_004616
TSPAN8
tetraspanin 8
chr6_+_64414389 2.464 NM_015153
PHF3
PHD finger protein 3
chrX_+_49718954 2.462 NM_000084
CLCN5
chloride channel 5
chr11_-_117640078 2.446


chr11_+_62813947 2.423 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr7_+_113842470 2.390 FOXP2
forkhead box P2
chr3_-_49434874 2.368 AMT
aminomethyltransferase
chr2_-_21081694 2.367 APOB
apolipoprotein B (including Ag(x) antigen)
chr1_-_150070849 2.361 NM_005060
RORC
RAR-related orphan receptor C
chr1_-_109651140 2.357 NM_001010985
MYBPHL
myosin binding protein H-like
chr5_+_175908948 2.353 NM_017675
CDHR2
cadherin-related family member 2
chr22_-_35835548 2.330 TMPRSS6
transmembrane protease, serine 6
chr17_-_31332568 2.282 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr14_-_37134050 2.281 FOXA1
forkhead box A1
chr3_+_187813405 2.277 AHSG
alpha-2-HS-glycoprotein
chr14_+_20493467 2.276 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chrX_-_10761729 2.223 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr2_+_71016503 2.212 NM_001692
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr1_-_57057956 2.210 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr3_-_12175646 2.207 NM_003256
TIMP4
TIMP metallopeptidase inhibitor 4
chr1_+_40486159 2.197 NM_001008740
TMCO2
transmembrane and coiled-coil domains 2
chr17_-_15463742 2.182 NM_006382
CDRT1
CMT1A duplicated region transcript 1
chr21_-_42608774 2.172 NM_003226
TFF3
trefoil factor 3 (intestinal)
chrX_-_15198093 2.167 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr11_+_62893836 2.110 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr12_+_25096472 2.088 NM_006152
LRMP
lymphoid-restricted membrane protein
chr4_-_40211324 2.083 RBM47
RNA binding motif protein 47
chr2_-_200033445 2.067 SATB2
SATB homeobox 2
chr7_+_99263571 2.046 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr10_+_104525877 2.045 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr10_+_123738678 2.023 NM_206861
NM_206862
TACC2

transforming, acidic coiled-coil containing protein 2

chrX_-_106033202 2.018 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr8_+_21967008 1.975 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr9_+_34643911 1.974 NM_004512
NM_147162
IL11RA

interleukin 11 receptor, alpha

chr10_+_51219558 1.963 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr4_+_74496575 1.944 ALB
albumin
chr16_-_4778317 1.937 NM_001154458
NM_144605
SEPT12

septin 12

chr20_-_49612574 1.930 NM_001136021
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr10_-_69267774 1.929 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr19_+_17723285 1.925 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr2_-_152538694 1.917 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr1_+_205344200 1.912 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr17_-_19231049 1.906 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr2_-_21084911 1.905 APOB
apolipoprotein B (including Ag(x) antigen)
chr2_+_3683660 1.883 NM_018436
ALLC
allantoicase
chr5_+_145296313 1.870 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr8_-_142307854 1.853 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr5_+_140583098 1.850 NM_018934
PCDHB14
protocadherin beta 14
chr4_+_155703581 1.850 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr10_+_89257569 1.843 NM_001178118
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr18_-_50777634 1.834 NM_025214
CCDC68
coiled-coil domain containing 68
chr22_+_22907443 1.823 NM_019601
SUSD2
sushi domain containing 2
chr17_+_7423704 1.816 CD68
CD68 molecule
chr19_-_10074332 1.814 NM_031917
ANGPTL6
angiopoietin-like 6
chr4_+_187424111 1.807 NM_000128
F11
coagulation factor XI
chr9_-_115880494 1.790 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr2_+_108271526 1.774 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr11_+_70954256 1.768 NM_001012710
KRTAP5-10
keratin associated protein 5-10
chr1_-_20682541 1.765


chr2_-_21120314 1.761 APOB
apolipoprotein B (including Ag(x) antigen)
chr1_-_159459999 1.753 NM_001643
APOA2
apolipoprotein A-II
chr10_+_101532450 1.749 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr9_-_116305273 1.733 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr6_+_31731647 1.726 NM_019101
APOM
apolipoprotein M
chr17_-_6958773 1.724 NM_001181
NM_080912
NM_080913
ASGR2


asialoglycoprotein receptor 2


chr14_+_38772870 1.715 NM_054024
MIA2
melanoma inhibitory activity 2
chr2_-_192419896 1.708 SDPR
serum deprivation response
chr11_-_10546654 1.707 NM_006691
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr11_+_22646229 1.689 NM_177553
GAS2
growth arrest-specific 2
chr4_-_70396167 1.666 NM_021139
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr17_+_7423685 1.657 CD68
CD68 molecule
chr2_+_241776596 1.656 NM_001001666
NM_001001891
ANO7

anoctamin 7

chr17_+_7423662 1.654 CD68
CD68 molecule
chr6_-_32227695 1.650 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr7_-_25234582 1.645 NM_022150
NPVF
neuropeptide VF precursor
chr12_-_9159789 1.641 NM_000014
A2M
alpha-2-macroglobulin
chr2_-_192420168 1.611 NM_004657
SDPR
serum deprivation response
chr6_+_64403668 1.608 PHF3
PHD finger protein 3
chr17_+_3324096 1.605 NM_001128085
ASPA
aspartoacylase
chr20_-_49612745 1.596 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr1_+_26376611 1.592 CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr7_+_94377145 1.581 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.16 1.27e-04 GO:0007606 sensory perception of chemical stimulus
5.02 5.13e-03 GO:0031214 biomineral tissue development
2.02 9.95e-03 GO:0007608 sensory perception of smell
1.22 1.44e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.58 5.76e-08 GO:0005576 extracellular region
1.69 8.57e-05 GO:0044421 extracellular region part
1.73 6.18e-04 GO:0005615 extracellular space

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.07 1.62e-03 GO:0004984 olfactory receptor activity
1.66 5.24e-03 GO:0004930 G-protein coupled receptor activity
2.68 7.56e-03 GO:0004866 endopeptidase inhibitor activity
2.58 1.46e-02 GO:0061135 endopeptidase regulator activity
2.55 1.81e-02 GO:0030414 peptidase inhibitor activity
3.12 2.36e-02 GO:0004867 serine-type endopeptidase inhibitor activity
2.32 4.11e-02 GO:0061134 peptidase regulator activity