Motif ID: FOXL1.p2

Z-value: 1.569


Transcription factors associated with FOXL1.p2:

Gene SymbolEntrez IDGene Name
FOXL1 2300 forkhead box L1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXL1chr16_+_851696150.332.1e-01Click!


Activity profile for motif FOXL1.p2.

activity profile for motif FOXL1.p2


Sorted Z-values histogram for motif FOXL1.p2

Sorted Z-values for motif FOXL1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_77801480 4.226 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chrX_-_33139349 3.207 NM_004006
DMD
dystrophin
chr12_+_79625538 3.185 NM_002469
MYF6
myogenic factor 6 (herculin)
chr4_+_169654742 3.018 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr7_+_110518297 2.783 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr13_+_110653407 2.638 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr4_-_71751205 2.608 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_+_151922350 2.546 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr7_+_18502342 2.461 NM_058176
NM_178425
HDAC9

histone deacetylase 9

chr1_+_190811479 2.419 NM_002922
RGS1
regulator of G-protein signaling 1
chr5_-_88155360 2.262 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr4_+_113958652 2.089 NM_001127493
ANK2
ankyrin 2, neuronal
chr10_-_31328426 2.085 NM_001143769
ZNF438
zinc finger protein 438
chr10_-_14090459 2.069 FRMD4A
FERM domain containing 4A
chr6_-_139654807 2.023 NM_153235
TXLNB
taxilin beta
chr6_+_136214495 1.915 NM_018945
PDE7B
phosphodiesterase 7B
chr3_+_190831909 1.912 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr4_-_71751070 1.898 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr19_+_55614006 1.674 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr1_+_160868822 1.640 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chrX_-_11194015 1.619 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr15_-_78050515 1.615 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr10_-_69095362 1.610 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr1_+_194887630 1.582 NM_000186
NM_001014975
CFH

complement factor H

chr10_-_75080784 1.561 NM_024875
SYNPO2L
synaptopodin 2-like
chr1_+_160868932 1.507 DDR2
discoidin domain receptor tyrosine kinase 2
chr20_+_11846536 1.506 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr14_+_87541220 1.485 NM_003608
GPR65
G protein-coupled receptor 65
chr15_-_40537002 1.478 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr1_-_42157077 1.456 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr9_-_94338072 1.441 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr1_+_84540921 1.441 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr2_-_179623030 1.437 NM_173648
CCDC141
coiled-coil domain containing 141
chr4_+_86968069 1.421 ARHGAP24
Rho GTPase activating protein 24
chr12_-_101115677 1.395 NM_002674
PMCH
pro-melanin-concentrating hormone
chr18_+_64616296 1.363 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr2_-_55090759 1.363 NM_007008
RTN4
reticulon 4
chr1_+_242281199 1.347 ZNF238
zinc finger protein 238
chr9_+_102380156 1.342 NM_001018116
MURC
muscle-related coiled-coil protein
chr4_-_138673078 1.339 NM_019035
PCDH18
protocadherin 18
chr7_+_90176647 1.294 NM_012395
CDK14
cyclin-dependent kinase 14
chr6_-_76259976 1.284 NM_015687
FILIP1
filamin A interacting protein 1
chr10_+_69539255 1.278 NM_032578
MYPN
myopalladin
chr1_+_13903936 1.261 NM_012231
NM_015866
PRDM2

PR domain containing 2, with ZNF domain

chr13_-_98757634 1.250 NM_004951
GPR183
G protein-coupled receptor 183
chr1_+_11171967 1.236 NM_021146
ANGPTL7
angiopoietin-like 7
chrX_-_135691168 1.233 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr2_+_143603368 1.215 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr1_-_42156913 1.191


chr3_-_152585226 1.181 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr11_-_83071084 1.180 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr18_+_30544193 1.144 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr15_+_55298908 1.143 NM_207040
TCF12
transcription factor 12
chr1_-_93172119 1.136


chr3_-_52688768 1.133 NM_018165
NM_181042
PBRM1

polybromo 1

chr3_+_44665220 1.132 NM_003420
ZNF35
zinc finger protein 35
chr3_-_195670256 1.131 NM_024524
ATP13A3
ATPase type 13A3
chr4_+_86918870 1.124 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr2_+_24660849 1.123 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr5_+_140772691 1.121 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr1_-_181540631 1.107 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr10_-_69125932 1.102 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr15_-_42756377 1.095 NM_001145112
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr4_+_86918882 1.091 ARHGAP24
Rho GTPase activating protein 24
chr7_+_93862137 1.091 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr5_+_76470829 1.059


chr16_+_14187965 1.053 MKL2
MKL/myocardin-like 2
chr2_-_207291364 1.044 NM_001093730
DYTN
dystrotelin
chr12_+_9713472 1.042 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr14_+_20319049 1.042 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr5_+_53787187 1.041 NM_006308
HSPB3
heat shock 27kDa protein 3
chr7_-_81237162 1.036 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr16_+_31132842 1.008 NM_001008274
TRIM72
tripartite motif containing 72
chr1_-_154727014 1.006 MEF2D
myocyte enhancer factor 2D
chr1_-_153107084 0.999


chr2_-_55053398 0.986


chrX_-_138742050 0.982 NM_001010986
NM_173694
ATP11C

ATPase, class VI, type 11C

chr4_-_44348414 0.982 NM_182592
YIPF7
Yip1 domain family, member 7
chr2_+_189547323 0.979 NM_000090
COL3A1
collagen, type III, alpha 1
chr1_+_100957883 0.973 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr8_+_70567634 0.970 SULF1
sulfatase 1
chr9_-_21472311 0.967 NM_176891
IFNE
interferon, epsilon
chr4_-_177427252 0.965 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr10_+_94584449 0.959 NM_001013848
EXOC6
exocyst complex component 6
chr11_-_17147863 0.958 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr7_+_143263191 0.958 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr13_+_45174446 0.954 NM_152719
SPERT
spermatid associated
chr2_-_63518589 0.951 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chr5_+_156628929 0.950 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_-_72057755 0.948 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr8_-_93099040 0.917 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_35658852 0.915 NM_016300
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr11_-_71424614 0.913


chr8_-_102872372 0.913 NCALD
neurocalcin delta
chr8_-_102872614 0.906 NM_032041
NCALD
neurocalcin delta
chr4_-_153523113 0.895 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr2_+_37282516 0.887 LOC100505876
hypothetical LOC100505876
chr7_+_80105858 0.877 CD36
CD36 molecule (thrombospondin receptor)
chr2_-_162808123 0.874 NM_004460
FAP
fibroblast activation protein, alpha
chr2_+_143603439 0.874 ARHGAP15
Rho GTPase activating protein 15
chr13_-_98708549 0.871 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr4_+_3341521 0.868 NM_198227
RGS12
regulator of G-protein signaling 12
chr7_-_113346284 0.856 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr3_-_143230124 0.856 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr17_-_60439764 0.854 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr5_-_94442941 0.848 MCTP1
multiple C2 domains, transmembrane 1
chr8_-_102872354 0.846 NCALD
neurocalcin delta
chr1_+_242281175 0.844 NM_205768
ZNF238
zinc finger protein 238
chr17_-_1211263 0.841 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr12_+_119572753 0.837 NM_004276
NM_031205
CABP1

calcium binding protein 1

chr12_-_18134319 0.837 NM_024730
RERGL
RERG/RAS-like
chr17_-_24491521 0.836 MYO18A
myosin XVIIIA
chr4_-_74307637 0.832 ANKRD17
ankyrin repeat domain 17
chr6_-_32665409 0.831 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chrX_+_77889861 0.828 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr20_+_43764068 0.827 NM_172005
WFDC13
WAP four-disulfide core domain 13
chr12_+_79362256 0.819 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr8_-_108579270 0.816 NM_001146
ANGPT1
angiopoietin 1
chr3_+_46423682 0.815 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr8_-_52884456 0.805 NM_144651
PXDNL
peroxidasin homolog (Drosophila)-like
chr2_-_105421661 0.801 NM_201557
FHL2
four and a half LIM domains 2
chr7_+_116447527 0.799 ST7
suppression of tumorigenicity 7
chr5_+_152850276 0.797 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr8_+_107807415 0.794 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr4_+_68107039 0.789 NM_012108
STAP1
signal transducing adaptor family member 1
chr1_+_200775864 0.786 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr10_+_90511142 0.770 NM_001102469
LIPN
lipase, family member N
chr11_+_10433241 0.769 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr1_-_199613427 0.768 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr1_-_246869181 0.767 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr12_-_52281050 0.762 NM_001130059
ATF7
activating transcription factor 7
chr17_-_36436979 0.762 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr17_-_34603577 0.759 CACNB1
calcium channel, voltage-dependent, beta 1 subunit
chr5_-_169657192 0.752 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_-_199613406 0.752 TNNT2
troponin T type 2 (cardiac)
chr8_-_102005697 0.752 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr9_-_116732403 0.751 NM_001244
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr1_+_149395728 0.750 NM_024575
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr1_-_115039614 0.748 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr10_+_50177192 0.740 NM_001135196
NM_199459
C10orf71

chromosome 10 open reading frame 71

chr1_+_207926172 0.740 NM_181755
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr10_-_98021144 0.737 NM_001114094
NM_013314
BLNK

B-cell linker

chr3_-_13032130 0.735


chr18_+_28023984 0.735 NM_005925
MEP1B
meprin A, beta
chr5_-_83052606 0.722 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr19_-_43608641 0.720 NM_001146202
NM_001146203
NM_001146204
NM_001146205
NM_001146206
NM_001146207
NM_170604
RASGRP4






RAS guanyl releasing protein 4






chr3_-_116272911 0.717 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr5_-_169657312 0.706 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_-_195601283 0.701 NM_004488
GP5
glycoprotein V (platelet)
chr4_+_38740246 0.699 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr10_-_97190885 0.695 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr4_+_114190233 0.694 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr14_-_30927931 0.692 NM_015473
HEATR5A
HEAT repeat containing 5A
chr11_+_5431213 0.691 NM_001004754
OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr4_+_72321113 0.689 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr5_-_169657395 0.689 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr18_-_65766068 0.687 CD226
CD226 molecule
chr1_-_27604656 0.685 WASF2
WAS protein family, member 2
chr1_-_239865724 0.683 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr15_-_68781662 0.681 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_+_63510481 0.675


chr13_-_45640679 0.675 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_113534604 0.672 NM_001004196
NM_005944
CD200

CD200 molecule

chr2_+_170074457 0.666 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr14_-_19252330 0.665 NM_001197287
OR11H2
olfactory receptor, family 11, subfamily H, member 2
chr14_+_22059212 0.660


chr17_-_10362583 0.659 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr1_-_51660328 0.657 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr17_-_26672757 0.655 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr9_-_99740243 0.653 NM_197978
HEMGN
hemogen
chr1_+_246682699 0.651 NM_001004136
OR2T2
olfactory receptor, family 2, subfamily T, member 2
chr12_-_110378240 0.651


chr13_+_49487390 0.649 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr4_+_120276386 0.647 NM_016599
MYOZ2
myozenin 2
chr5_+_140757787 0.645 NM_018925
NM_032099
PCDHGB5

protocadherin gamma subfamily B, 5

chr1_+_84539876 0.643 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr11_-_5212168 0.641 NM_000519
HBD
hemoglobin, delta
chr12_-_90097384 0.640 NM_133503
DCN
decorin
chr20_+_58146916 0.640 LOC284757
hypothetical protein LOC284757
chr22_-_37211467 0.634 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr12_-_122400937 0.633 NM_001167856
NM_018183
SBNO1

strawberry notch homolog 1 (Drosophila)

chr1_+_40635058 0.623 NM_001198980
SMAP2
small ArfGAP2
chr1_+_78888064 0.623 NM_006417
IFI44
interferon-induced protein 44
chr8_-_142333339 0.619 SLC45A4
solute carrier family 45, member 4
chr14_+_22059174 0.616


chr7_+_91762227 0.613


chr17_-_9870292 0.613 NM_001130831
GAS7
growth arrest-specific 7
chr6_-_133120587 0.608 NM_004665
VNN2
vanin 2
chr7_+_111908143 0.606 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr7_-_143213296 0.604 FAM115A
family with sequence similarity 115, member A
chr5_+_65408500 0.602 ERBB2IP
erbb2 interacting protein
chr5_-_169657360 0.601 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr12_-_90100679 0.600 DCN
decorin
chr5_-_111119846 0.600 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr7_+_136203938 0.599 NM_001006627
NM_001006630
CHRM2

cholinergic receptor, muscarinic 2

chr8_-_82557956 0.598 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr2_-_198248828 0.593 NM_144629
RFTN2
raftlin family member 2
chr2_-_99412694 0.589 REV1
REV1 homolog (S. cerevisiae)
chr2_-_88946767 0.589


chr5_-_150501393 0.586 NM_001193544
ANXA6
annexin A6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.92 1.21e-13 GO:0007608 sensory perception of smell
2.65 1.82e-11 GO:0007606 sensory perception of chemical stimulus
1.75 1.28e-10 GO:0003008 system process
1.35 8.09e-10 GO:0032501 multicellular organismal process
1.30 3.28e-09 GO:0050896 response to stimulus
3.44 5.65e-09 GO:0007517 muscle organ development
2.03 1.92e-08 GO:0007600 sensory perception
1.77 3.11e-08 GO:0050877 neurological system process
2.62 1.01e-05 GO:0061061 muscle structure development
4.23 6.63e-04 GO:0007519 skeletal muscle tissue development
1.45 8.36e-04 GO:0030154 cell differentiation
3.97 1.76e-03 GO:0060538 skeletal muscle organ development
1.36 1.80e-03 GO:0048731 system development
2.99 1.85e-03 GO:0060537 muscle tissue development
1.42 2.07e-03 GO:0048869 cellular developmental process
1.68 2.39e-03 GO:0009611 response to wounding
1.29 3.94e-03 GO:0023052 signaling
3.01 4.56e-03 GO:0014706 striated muscle tissue development
1.55 5.25e-03 GO:0002376 immune system process
1.72 5.31e-03 GO:0006955 immune response
1.43 6.40e-03 GO:0048513 organ development
6.04 1.76e-02 GO:0071248 cellular response to metal ion
1.41 1.83e-02 GO:0048583 regulation of response to stimulus
1.91 1.93e-02 GO:0050776 regulation of immune response
1.30 1.96e-02 GO:0048856 anatomical structure development
1.63 2.28e-02 GO:0009888 tissue development
1.40 4.02e-02 GO:0007166 cell surface receptor linked signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.43 2.36e-12 GO:0071944 cell periphery
1.43 3.79e-12 GO:0005886 plasma membrane
2.38 9.97e-06 GO:0005578 proteinaceous extracellular matrix
1.69 1.89e-05 GO:0044421 extracellular region part
1.43 1.44e-04 GO:0005576 extracellular region
2.09 2.70e-04 GO:0031012 extracellular matrix
1.60 9.90e-03 GO:0005615 extracellular space
2.66 1.86e-02 GO:0030016 myofibril
2.59 4.00e-02 GO:0044449 contractile fiber part
2.51 4.32e-02 GO:0043292 contractile fiber

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.06 1.73e-15 GO:0004984 olfactory receptor activity
2.22 3.92e-13 GO:0004930 G-protein coupled receptor activity
1.83 7.36e-10 GO:0004888 transmembrane receptor activity
1.57 2.98e-08 GO:0004871 signal transducer activity
1.57 2.98e-08 GO:0060089 molecular transducer activity
1.62 7.93e-08 GO:0004872 receptor activity
2.00 1.02e-02 GO:0003779 actin binding
9.64 2.95e-02 GO:0005132 interferon-alpha/beta receptor binding