Motif ID: GATA1..3.p2

Z-value: 2.007


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA3chr10_+_81366390.611.2e-02Click!
GATA2chr3_-_129690056-0.582.0e-02Click!
GATA1chrX_+_48529905-0.019.8e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_93176819 2.249 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_30799130 2.222 TUBB
tubulin, beta
chr3_-_129023850 2.199 NM_007283
 MGLL
monoglyceride lipase
chr5_+_140870881 2.141


chr7_-_81237162 2.006 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
 HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr8_-_93176618 1.878 NM_001198629
NM_001198630
NM_001198632
NM_175635
 RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr5_+_140871107 1.878


chr8_-_93099040 1.859 NM_175636
 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_105427898 1.834 SH3PXD2A
SH3 and PX domains 2A
chr17_-_45629401 1.796


chr9_+_112470871 1.788 NM_001166280
NM_001166281
NM_005592
 MUSK


muscle, skeletal, receptor tyrosine kinase


chrX_-_154216929 1.786 NM_001289
 CLIC2
chloride intracellular channel 2
chrX_-_57953578 1.735 NM_007156
 ZXDA
zinc finger, X-linked, duplicated A
chr18_-_51219880 1.720 TCF4
transcription factor 4
chr7_+_18501876 1.717 NM_014707
NM_178423
 HDAC9

histone deacetylase 9

chr12_+_79625538 1.704 NM_002469
 MYF6
myogenic factor 6 (herculin)
chr17_-_45626364 1.668


chr11_-_35503720 1.631 NM_001001991
NM_015430
 PAMR1

peptidase domain containing associated with muscle regeneration 1

chr1_-_26517342 1.611 NM_145345
 UBXN11
UBX domain protein 11
chr8_-_108579270 1.609 NM_001146
 ANGPT1
angiopoietin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
1.73 3.44e-02 GO:0042391 regulation of membrane potential
1.40 8.35e-03 GO:0019226 transmission of nerve impulse
1.40 8.35e-03 GO:0035637 multicellular organismal signaling
1.40 3.19e-02 GO:0007268 synaptic transmission
1.32 3.69e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.31 1.34e-02 GO:0007267 cell-cell signaling
1.28 1.48e-02 GO:0022008 neurogenesis
1.27 4.01e-05 GO:0007399 nervous system development
1.27 1.32e-04 GO:0050877 neurological system process
1.27 1.37e-02 GO:0007154 cell communication
1.26 4.75e-06 GO:0003008 system process
1.23 9.89e-03 GO:0009966 regulation of signal transduction
1.21 3.32e-07 GO:0048731 system development
1.21 1.10e-02 GO:0023051 regulation of signaling
1.19 1.87e-06 GO:0048856 anatomical structure development
1.19 7.95e-05 GO:0048518 positive regulation of biological process
1.19 1.80e-03 GO:0048523 negative regulation of cellular process
1.18 3.03e-07 GO:0023052 signaling
1.18 2.77e-06 GO:0007275 multicellular organismal development
1.18 8.51e-06 GO:0007165 signal transduction

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.78 6.75e-04 GO:0034703 cation channel complex
1.50 3.23e-02 GO:0034702 ion channel complex
1.15 1.07e-03 GO:0043234 protein complex
1.15 4.49e-02 GO:0005829 cytosol
1.13 1.13e-03 GO:0032991 macromolecular complex
1.06 9.49e-03 GO:0005737 cytoplasm
1.05 8.00e-03 GO:0044424 intracellular part
1.03 1.17e-06 GO:0005623 cell
1.03 1.51e-06 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
3.05 3.85e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
2.61 1.24e-02 GO:0008066 glutamate receptor activity
1.63 3.92e-02 GO:0022843 voltage-gated cation channel activity
1.55 1.72e-02 GO:0000975 regulatory region DNA binding
1.55 1.72e-02 GO:0001067 regulatory region nucleic acid binding
1.55 1.72e-02 GO:0044212 transcription regulatory region DNA binding
1.55 2.44e-02 GO:0010843 promoter binding
1.54 4.23e-02 GO:0005244 voltage-gated ion channel activity
1.54 4.23e-02 GO:0022832 voltage-gated channel activity
1.47 5.57e-03 GO:0022836 gated channel activity
1.44 2.53e-02 GO:0016564 transcription repressor activity
1.30 1.70e-04 GO:0030528 transcription regulator activity
1.29 2.27e-02 GO:0043565 sequence-specific DNA binding
1.11 8.14e-09 GO:0005515 protein binding