Motif ID: GFI1B.p2

Z-value: 2.539


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1Bchr9_+_134843918-0.901.9e-06Click!


Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_15080586 10.551 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr4_+_183302105 8.531 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr9_+_676640 8.186


chr2_-_142605010 7.448 LRP1B
low density lipoprotein receptor-related protein 1B
chr12_-_28016182 6.736 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chrX_-_43717864 6.694 NM_000266
NDP
Norrie disease (pseudoglioma)
chr2_+_219180821 6.208 PLCD4
phospholipase C, delta 4
chr2_+_219180862 6.091 PLCD4
phospholipase C, delta 4
chr2_+_219180875 6.043 NM_032726
PLCD4
phospholipase C, delta 4
chr4_-_23500706 5.853 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_+_66570683 5.648 PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_-_189752575 5.548 NM_000393
COL5A2
collagen, type V, alpha 2
chr1_-_197173159 5.496 LOC100131234
familial acute myelogenous leukemia related factor
chr15_-_81744469 5.360 NM_001717
BNC1
basonuclin 1
chr14_+_95792299 5.146 NM_000710
BDKRB1
bradykinin receptor B1
chr6_+_12398514 5.051 NM_001168319
NM_001955
EDN1

endothelin 1

chr5_-_59100091 4.853 PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_177378801 4.787 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr15_+_60146467 4.569 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr3_-_192063158 4.472 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr7_-_81910956 4.406 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr5_+_66160359 4.341 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_+_161305558 4.283 NM_001113381
RGS4
regulator of G-protein signaling 4
chr1_+_101475149 4.249 S1PR1
sphingosine-1-phosphate receptor 1
chr11_-_35503720 4.154 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr1_+_218768423 4.095 MARK1
MAP/microtubule affinity-regulating kinase 1
chr1_+_66570363 4.022 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_+_101474892 3.860 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr17_-_26672757 3.846 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr3_-_135231518 3.747 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr3_-_159872960 3.730 NM_020169
LXN
latexin
chr3_-_113842350 3.648 CCDC80
coiled-coil domain containing 80
chr3_-_64186151 3.481 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr5_-_137099602 3.387 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr8_-_19584373 3.384 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr12_+_83954229 3.372 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr18_-_33399997 3.365 NM_001025087
NM_001025088
NM_001025089
NM_020180
CELF4



CUGBP, Elav-like family member 4



chr6_-_26125939 3.262 NM_005325
HIST1H1A
histone cluster 1, H1a
chr12_-_22378833 3.218 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr14_+_20580224 3.213 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chr17_-_67628523 3.113 FLJ37644
hypothetical LOC400618
chr7_+_18515440 3.047 HDAC9
histone deacetylase 9
chr11_-_102100833 3.029 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr8_+_67946290 2.975 NM_001136160
C8orf45
chromosome 8 open reading frame 45
chrX_-_10548458 2.971 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr7_-_81910740 2.943 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr4_+_120167264 2.912 SYNPO2
synaptopodin 2
chr12_-_83954185 2.905 NM_001100917
TSPAN19
tetraspanin 19
chr7_+_18515488 2.904 HDAC9
histone deacetylase 9
chr4_+_86968069 2.903 ARHGAP24
Rho GTPase activating protein 24
chr6_+_152168500 2.814 NM_001122741
ESR1
estrogen receptor 1
chr3_-_113842255 2.785 CCDC80
coiled-coil domain containing 80
chr1_+_216585298 2.783 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr17_+_67628763 2.782 SOX9
SRY (sex determining region Y)-box 9
chrX_+_17303270 2.758 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr2_+_98070026 2.742 NM_144992
VWA3B
von Willebrand factor A domain containing 3B
chr2_+_61225710 2.696 NM_001143960
C2orf74
chromosome 2 open reading frame 74
chr5_-_22889487 2.672 NM_004061
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr4_+_113958652 2.663 NM_001127493
ANK2
ankyrin 2, neuronal
chr6_-_134540666 2.652 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr3_-_113842237 2.629 CCDC80
coiled-coil domain containing 80
chr5_+_102229425 2.537 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr18_+_30327341 2.527 DTNA
dystrobrevin, alpha
chr14_-_36121536 2.485 NM_014360
NKX2-8
NK2 homeobox 8
chr17_+_67628772 2.467 SOX9
SRY (sex determining region Y)-box 9
chr10_-_91001542 2.456 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr5_-_20024050 2.455 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr4_+_41234944 2.425 LIMCH1
LIM and calponin homology domains 1
chr3_-_188936941 2.420 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr3_-_113842553 2.380 CCDC80
coiled-coil domain containing 80
chr10_-_91001531 2.347 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr10_-_91001496 2.306 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr5_-_22889192 2.286 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr1_+_161305188 2.273 NM_005613
RGS4
regulator of G-protein signaling 4
chr16_+_70117523 2.269 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr21_+_29439768 2.192 C21orf7
chromosome 21 open reading frame 7
chr3_-_113842652 2.182 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chrX_+_17303727 2.174 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chrX_+_17303458 2.151 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr9_-_90983501 2.141 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr18_+_53863865 2.128 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr11_-_40272239 2.090 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr3_+_161040343 2.060 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr2_-_164300758 2.045 NM_018086
FIGN
fidgetin
chr12_-_14929991 1.990 NM_000900
NM_001190839
MGP

matrix Gla protein

chr13_-_77391525 1.975


chr8_-_93099040 1.960 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_116184846 1.960 NM_001111061
NHLH2
nescient helix loop helix 2
chr11_+_18244383 1.908 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr13_-_85271329 1.902 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr1_+_154520693 1.888 NM_032323
TMEM79
transmembrane protein 79
chr1_-_116185215 1.849 NM_005599
NHLH2
nescient helix loop helix 2
chr2_-_113259441 1.842 NM_000575
IL1A
interleukin 1, alpha
chr10_+_104525877 1.804 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr2_+_176695658 1.800 NM_014213
HOXD9
homeobox D9
chr6_+_26128656 1.740 NM_003529
HIST1H3A
histone cluster 1, H3a
chr4_+_42094612 1.740 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr11_+_5667494 1.733 NM_006074
TRIM22
tripartite motif containing 22
chr18_+_30327243 1.724 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr11_-_102219450 1.717 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr5_-_137099361 1.656 KLHL3
kelch-like 3 (Drosophila)
chr7_-_27171673 1.654 NM_152739
HOXA9
homeobox A9
chr11_-_8849485 1.641 ST5
suppression of tumorigenicity 5
chr2_+_162908828 1.612 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr6_-_152744143 1.595 SYNE1
spectrin repeat containing, nuclear envelope 1
chrX_+_17303798 1.579 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr2_-_113310796 1.567 NM_000576
IL1B
interleukin 1, beta
chr11_+_111551417 1.557 NM_031938
BCO2
beta-carotene oxygenase 2
chr6_-_31756119 1.553 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr1_-_214963279 1.548 NM_001438
ESRRG
estrogen-related receptor gamma
chr1_-_7998265 1.546 ERRFI1
ERBB receptor feedback inhibitor 1
chr3_+_190372456 1.544 NM_198485
TPRG1
tumor protein p63 regulated 1
chr15_-_74091817 1.541 NM_138573
NRG4
neuregulin 4
chr12_-_113328271 1.539 NM_181486
TBX5
T-box 5
chr1_-_188713324 1.537 NM_199051
FAM5C
family with sequence similarity 5, member C
chr17_+_56884560 1.531 TBX4
T-box 4
chr17_+_71232370 1.521 NM_001005619
ITGB4
integrin, beta 4
chrX_-_57953578 1.517 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr16_-_73859451 1.506 NM_001170715
BCAR1
breast cancer anti-estrogen resistance 1
chr13_-_47885248 1.500 LPAR6
lysophosphatidic acid receptor 6
chr2_+_166034402 1.482 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr6_-_138862271 1.462 NM_001144060
NHSL1
NHS-like 1
chr1_+_46151845 1.439 MAST2
microtubule associated serine/threonine kinase 2
chr3_-_191522886 1.391 NM_021101
CLDN1
claudin 1
chr1_-_79244948 1.377 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr3_+_113200696 1.375 NM_001008273
TAGLN3
transgelin 3
chr1_+_107485071 1.368 NTNG1
netrin G1
chr8_+_26206648 1.354 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_+_218768146 1.349 MARK1
MAP/microtubule affinity-regulating kinase 1
chr17_-_70901303 1.342 GRB2
growth factor receptor-bound protein 2
chr14_-_49652944 1.334 NM_001040662
NM_024558
METTL21D

methyltransferase like 21D

chr17_+_67628749 1.330 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr1_-_17180659 1.330 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr7_-_27171648 1.326 HOXA9
homeobox A9
chr6_-_166960649 1.319 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr11_-_85074848 1.315 NM_152723
CCDC89
coiled-coil domain containing 89
chr2_-_53940571 1.308 NM_001164165
NM_006794
GPR75-ASB3
GPR75
GPR75-ASB3 read-through transcript
G protein-coupled receptor 75
chr2_+_28887203 1.300 NM_001142634
NM_182756
SPDYA

speedy homolog A (Xenopus laevis)

chr4_+_41235077 1.282 LIMCH1
LIM and calponin homology domains 1
chr18_+_42780784 1.282 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr12_-_111114908 1.274 C12orf51
chromosome 12 open reading frame 51
chr2_-_133895795 1.237 NCKAP5
NCK-associated protein 5
chr7_-_27171600 1.233 HOXA9
homeobox A9
chr11_-_128279670 1.230 C11orf45
chromosome 11 open reading frame 45
chr5_+_15553288 1.217 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr10_-_91393610 1.212 NM_138316
NM_148978
PANK1

pantothenate kinase 1

chr4_-_87247829 1.186 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr2_+_183290912 1.183 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr1_-_68470585 1.168 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr2_+_204440753 1.137 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr1_-_21373816 1.127 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr3_+_48482213 1.123 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr1_+_219026661 1.120 NM_022746
MOSC1
MOCO sulphurase C-terminal domain containing 1
chr7_+_28415495 1.118 LOC401317
hypothetical LOC401317
chr3_+_187840842 1.118 NM_014375
FETUB
fetuin B
chr3_-_155630197 1.117 NM_001038705
GPR149
G protein-coupled receptor 149
chr10_+_118177371 1.113 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr20_-_51633042 1.101 NM_006526
ZNF217
zinc finger protein 217
chr5_-_171643247 1.100 UBTD2
ubiquitin domain containing 2
chr1_+_157246305 1.099 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr12_-_8706746 1.091 MFAP5
microfibrillar associated protein 5
chr11_+_111294810 1.088 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr4_-_77147625 1.086 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr6_-_161614962 1.076 NM_020133
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr4_-_186537145 1.076 NM_018409
LRP2BP
LRP2 binding protein
chr14_+_69021149 1.072 NM_001161498
UPF0639
UPF0639 protein
chr19_+_51190535 1.062 CCDC61
coiled-coil domain containing 61
chr1_+_162795538 1.060 PBX1
pre-B-cell leukemia homeobox 1
chr22_-_34564611 1.047 RPL41P5
ribosomal protein L41 pseudogene 5
chr20_-_56859352 1.046 GNAS-AS1
GNAS antisense RNA 1 (non-protein coding)
chr6_-_138862273 1.044


chr2_+_162908869 1.038 GCA
grancalcin, EF-hand calcium binding protein
chr9_+_1040367 1.028 DMRT2
doublesex and mab-3 related transcription factor 2
chr3_-_159932965 1.027 NM_002888
NM_206963
RARRES1

retinoic acid receptor responder (tazarotene induced) 1

chr10_-_90702490 1.027 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chrX_-_21586337 1.026 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr9_+_91123204 1.026 NM_024077
SECISBP2
SECIS binding protein 2
chr9_-_16860719 1.014 NM_017637
BNC2
basonuclin 2
chr3_+_120904555 1.013 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr11_+_27019084 0.987 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr3_+_173951163 0.985 ECT2
epithelial cell transforming sequence 2 oncogene
chr9_+_136673464 0.980 NM_000093
COL5A1
collagen, type V, alpha 1
chr5_-_146813343 0.975 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr11_+_5667392 0.965 TRIM22
tripartite motif containing 22
chr19_-_15252261 0.950 NM_014299
NM_058243
BRD4

bromodomain containing 4

chr5_+_102229612 0.941 PAM
peptidylglycine alpha-amidating monooxygenase
chr9_-_90983195 0.941 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chrX_+_100692071 0.938 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr11_-_117305277 0.931 NM_001077263
TMPRSS13
transmembrane protease, serine 13
chr3_-_150578023 0.927 TM4SF1
transmembrane 4 L six family member 1
chr18_+_19706979 0.926 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr5_-_58607673 0.925 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_-_106401514 0.921 NM_001004482
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr22_+_36533845 0.918 NM_001171690
NM_014291
GCAT

glycine C-acetyltransferase

chr8_+_67945537 0.909 NM_001136161
NM_173518
C8orf45

chromosome 8 open reading frame 45

chr6_-_166960690 0.908 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr13_-_35327798 0.888 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr14_-_72430545 0.886 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr3_-_152517204 0.886 NM_023915
GPR87
G protein-coupled receptor 87
chr8_+_32698892 0.886 NM_001159996
NRG1
neuregulin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.41 1.79e-02 GO:0002757 immune response-activating signal transduction
3.33 2.43e-02 GO:0002764 immune response-regulating signaling pathway

Nothing significant found in compartment category.

Nothing significant found in function category.