Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.986


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
UBTFchr17_-_39651189-0.712.0e-03Click!
HMGB2chr4_-_1744912700.332.1e-01Click!
HBP1chr7_+_106596641-0.175.3e-01Click!
HMGB3chrX_+_1499024150.126.5e-01Click!
SSRP1chr11_-_568599000.107.1e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_23816062 14.433 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr6_+_21774624 10.797 FLJ22536
hypothetical locus LOC401237
chr17_-_46479127 10.521 SPAG9
sperm associated antigen 9
chr2_-_162808123 9.653 NM_004460
FAP
fibroblast activation protein, alpha
chr15_+_45797977 9.653 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr9_+_18464090 8.742 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr13_-_98428244 8.696 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr7_+_134114957 8.536 CALD1
caldesmon 1
chr9_+_18464138 8.385 ADAMTSL1
ADAMTS-like 1
chr7_+_134114912 8.378 CALD1
caldesmon 1
chr6_-_111995213 8.307 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr8_-_108579270 8.227 NM_001146
ANGPT1
angiopoietin 1
chr2_-_56266408 8.196 LOC100129434
hypothetical LOC100129434
chr12_-_16649211 8.175 LMO3
LIM domain only 3 (rhombotin-like 2)
chr15_-_53996597 8.163 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr11_-_85108030 8.157 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr16_+_85169615 7.860 NM_005250
FOXL1
forkhead box L1
chr8_-_72436519 7.849 EYA1
eyes absent homolog 1 (Drosophila)
chr6_+_12398514 7.674 NM_001168319
NM_001955
EDN1

endothelin 1

chr7_-_83662152 7.649 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_-_85107569 7.436 NM_206929
SYTL2
synaptotagmin-like 2
chr8_+_70567634 7.039 SULF1
sulfatase 1
chr8_+_70567581 6.803 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr7_-_27108826 6.795 NM_006735
HOXA2
homeobox A2
chr3_-_116272911 6.772 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_81544432 6.737 LPHN2
latrophilin 2
chr10_+_86174665 6.587 FAM190B
family with sequence similarity 190, member B
chr7_-_27186400 6.369 NM_153715
HOXA10
homeobox A10
chr6_-_56824672 6.337 DST
dystonin
chr6_-_139654807 6.218 NM_153235
TXLNB
taxilin beta
chrX_-_19598912 6.186 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr13_-_109757442 6.138 NM_001845
COL4A1
collagen, type IV, alpha 1
chr7_-_27153892 6.011 NM_024014
HOXA6
homeobox A6
chr21_-_27261276 5.987 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr5_-_44424423 5.978 NM_004465
FGF10
fibroblast growth factor 10
chr6_+_148705421 5.779 NM_015278
SASH1
SAM and SH3 domain containing 1
chr8_-_93144366 5.766 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_108665168 5.765 NM_021224
ZNF462
zinc finger protein 462
chr14_+_85066265 5.753 FLRT2
fibronectin leucine rich transmembrane protein 2
chr10_-_62002672 5.747 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_+_174598937 5.704 NM_014932
NLGN1
neuroligin 1
chr4_+_86918882 5.663 ARHGAP24
Rho GTPase activating protein 24
chr18_+_7936885 5.652 PTPRM
protein tyrosine phosphatase, receptor type, M
chr8_-_93144039 5.626


chr4_-_138673078 5.624 NM_019035
PCDH18
protocadherin 18
chr14_+_85066207 5.574 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chrX_-_33267646 5.534 NM_000109
DMD
dystrophin
chr7_-_41709191 5.531 NM_002192
INHBA
inhibin, beta A
chr13_-_73605914 5.502 NM_007249
KLF12
Kruppel-like factor 12
chr6_-_56824371 5.452 DST
dystonin
chr6_-_94185780 5.430 NM_004440
EPHA7
EPH receptor A7
chr7_-_11838260 5.361 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr21_-_31853160 5.360 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr5_-_83052606 5.337 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr8_-_72437020 5.334 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr14_-_91483325 5.328 FBLN5
fibulin 5
chrX_+_77889861 5.297 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr5_-_111119846 5.256 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr9_+_102380156 5.188 NM_001018116
MURC
muscle-related coiled-coil protein
chr20_+_11846536 5.182 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr5_+_15553736 5.162 FBXL7
F-box and leucine-rich repeat protein 7
chr3_-_145049853 5.070 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr2_+_33213111 4.962 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr1_-_191422346 4.956 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chrX_+_86659370 4.949 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chrX_-_99778340 4.938 NM_003270
TSPAN6
tetraspanin 6
chr9_-_72673753 4.936 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr3_+_148593911 4.936


chr9_-_16717887 4.839 BNC2
basonuclin 2
chr1_-_68470585 4.833 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chrX_-_62891066 4.802 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr18_-_29412148 4.701


chr3_-_188936941 4.642 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr11_+_101488380 4.614 NM_001195045
YAP1
Yes-associated protein 1
chr11_+_129496792 4.569 APLP2
amyloid beta (A4) precursor-like protein 2
chr7_-_27149750 4.564 NM_019102
HOXA5
homeobox A5
chr13_-_47885018 4.549 LPAR6
lysophosphatidic acid receptor 6
chr3_+_100840129 4.535 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr12_-_24606616 4.504 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr8_-_72436832 4.489 EYA1
eyes absent homolog 1 (Drosophila)
chr4_-_111777651 4.476 PITX2
paired-like homeodomain 2
chr1_-_197173159 4.451 LOC100131234
familial acute myelogenous leukemia related factor
chr15_+_47502666 4.437 NM_002009
FGF7
fibroblast growth factor 7
chr14_+_76298693 4.410 VASH1
vasohibin 1
chr5_+_15553539 4.408 FBXL7
F-box and leucine-rich repeat protein 7
chr3_-_115960807 4.281 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr11_+_131285747 4.257 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr5_+_15553288 4.238 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr5_-_83716346 4.226 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr6_+_148705817 4.222 SASH1
SAM and SH3 domain containing 1
chr15_-_68781662 4.216 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_-_224993498 4.160 NM_002221
ITPKB
inositol 1,4,5-trisphosphate 3-kinase B
chr12_+_83954229 4.152 NM_001079910
NM_032165
LRRIQ1

leucine-rich repeats and IQ motif containing 1

chr3_-_55496370 4.116 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr8_-_6407882 4.109 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr1_+_161305188 4.040 NM_005613
RGS4
regulator of G-protein signaling 4
chr3_-_11585264 4.032 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr14_-_91483757 3.991 NM_006329
FBLN5
fibulin 5
chr6_+_31190505 3.981 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr20_+_19818209 3.976 NM_018993
RIN2
Ras and Rab interactor 2
chr19_+_12996368 3.954 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_+_131286513 3.921 NTM
neurotrimin
chr2_-_188021117 3.901 NM_005795
CALCRL
calcitonin receptor-like
chr7_+_102340579 3.855 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr3_+_182900081 3.842 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr4_-_101658094 3.837 NM_001159694
NM_016242
EMCN

endomucin

chr6_+_148705646 3.836 SASH1
SAM and SH3 domain containing 1
chr5_-_83715947 3.777 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr10_+_75343352 3.768 PLAU
plasminogen activator, urokinase
chr4_-_152368492 3.707 SH3D19
SH3 domain containing 19
chr4_+_146623405 3.696 NM_001003688
SMAD1
SMAD family member 1
chr17_-_76985538 3.670


chr9_+_123501186 3.659 DAB2IP
DAB2 interacting protein
chr13_-_47885248 3.657 LPAR6
lysophosphatidic acid receptor 6
chr2_-_164300758 3.656 NM_018086
FIGN
fidgetin
chr12_-_83954185 3.651 NM_001100917
TSPAN19
tetraspanin 19
chr2_-_213723298 3.640 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr3_+_89239494 3.610 EPHA3
EPH receptor A3
chr4_-_152366970 3.607 NM_001009555
NM_001128923
SH3D19

SH3 domain containing 19

chr9_-_94338072 3.605 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr10_-_118887801 3.559 NM_001112704
NM_199131
VAX1

ventral anterior homeobox 1

chr3_+_89239363 3.530 NM_005233
NM_182644
EPHA3

EPH receptor A3

chr1_+_84540921 3.525 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr1_+_176577228 3.485 NM_004841
RASAL2
RAS protein activator like 2
chr3_-_55496607 3.455 WNT5A
wingless-type MMTV integration site family, member 5A
chr12_+_13240983 3.444 EMP1
epithelial membrane protein 1
chr2_-_72228427 3.438 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chrX_-_33139349 3.428 NM_004006
DMD
dystrophin
chr3_-_115825742 3.371 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_129023850 3.364 NM_007283
MGLL
monoglyceride lipase
chr12_+_13240987 3.353 EMP1
epithelial membrane protein 1
chr2_-_133144094 3.345 LYPD1
LY6/PLAUR domain containing 1
chr3_-_150533948 3.305 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr1_+_15145001 3.275 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr1_-_50661716 3.247 NM_032110
DMRTA2
DMRT-like family A2
chr18_+_29412538 3.242 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr4_+_183302105 3.171 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr6_-_134680888 3.170 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr4_-_111777584 3.167 PITX2
paired-like homeodomain 2
chr13_-_32678142 3.164 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr3_+_114414064 3.153 NM_033254
BOC
Boc homolog (mouse)
chr8_-_93099040 3.152 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_125956996 3.143 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chrX_+_100220491 3.142 NM_021637
TMEM35
transmembrane protein 35
chr9_-_8723893 3.105 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr3_-_194118321 3.102 MB21D2
Mab-21 domain containing 2
chr7_+_28692122 3.100 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr7_+_27190688 3.094


chr5_-_16989371 3.090 NM_012334
MYO10
myosin X
chr12_-_88270375 3.069 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr13_+_110653407 3.037 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr4_-_138673014 3.015 PCDH18
protocadherin 18
chr19_+_12996830 3.008 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr4_+_86918870 3.004 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr6_-_138935359 3.001 NM_020464
NHSL1
NHS-like 1
chr21_+_38550739 3.001 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_-_152999678 3.001 NM_033071
SYNE1
spectrin repeat containing, nuclear envelope 1
chr11_+_57547928 2.987 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr5_+_98132898 2.975 NM_001012761
RGMB
RGM domain family, member B
chr7_-_27171673 2.971 NM_152739
HOXA9
homeobox A9
chr3_-_65999548 2.956 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr8_-_29262240 2.952 NM_057158
DUSP4
dual specificity phosphatase 4
chr6_-_134540666 2.949 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr1_+_66570363 2.931 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_+_104525877 2.919 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr12_-_8706533 2.914 MFAP5
microfibrillar associated protein 5
chr1_-_242073094 2.912 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr16_-_71639670 2.902 NM_006885
ZFHX3
zinc finger homeobox 3
chr4_+_141397889 2.892 NM_032547
SCOC
short coiled-coil protein
chrX_-_50573759 2.885 NM_020717
SHROOM4
shroom family member 4
chr12_-_16650687 2.870 LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_207668787 2.861 NM_001104548
LOC642587
NPC-A-5
chr14_+_76297885 2.857 NM_014909
VASH1
vasohibin 1
chr19_+_12996745 2.832 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr7_+_18501876 2.791 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr9_+_676640 2.783


chr5_-_16989290 2.781 MYO10
myosin X
chr3_-_113842133 2.776 CCDC80
coiled-coil domain containing 80
chr5_+_15553768 2.769 FBXL7
F-box and leucine-rich repeat protein 7
chr3_-_113842255 2.737 CCDC80
coiled-coil domain containing 80
chr13_-_37341859 2.729 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr3_+_62280435 2.726 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr1_+_168898898 2.716 PRRX1
paired related homeobox 1
chr7_+_134226727 2.705 CALD1
caldesmon 1
chr3_-_113842237 2.700 CCDC80
coiled-coil domain containing 80
chrX_+_135079461 2.698 NM_001167819
FHL1
four and a half LIM domains 1
chr7_-_27190882 2.697 HOXA11
homeobox A11
chr12_-_16650697 2.690 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_-_113841967 2.689 CCDC80
coiled-coil domain containing 80
chr5_+_170668892 2.675 NM_021025
TLX3
T-cell leukemia homeobox 3
chr10_-_116434364 2.671 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr3_+_190990142 2.662 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr10_-_14090459 2.661 FRMD4A
FERM domain containing 4A
chr5_-_147266257 2.644 NM_206966
C5orf46
chromosome 5 open reading frame 46
chr2_+_36777336 2.641 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr8_-_70908130 2.629 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr14_+_62740878 2.625 NM_020663
RHOJ
ras homolog gene family, member J
chr7_+_134114701 2.610 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr10_+_80672842 2.610 ZMIZ1
zinc finger, MIZ-type containing 1
chr4_-_186814852 2.608 SORBS2
sorbin and SH3 domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 8.54e-19 GO:0032502 developmental process
1.43 1.31e-18 GO:0007275 multicellular organismal development
1.45 4.94e-18 GO:0048856 anatomical structure development
1.48 5.00e-18 GO:0048731 system development
1.65 4.25e-15 GO:0007399 nervous system development
1.63 4.08e-14 GO:0009653 anatomical structure morphogenesis
1.27 2.32e-12 GO:0032501 multicellular organismal process
1.44 1.83e-09 GO:0030154 cell differentiation
1.43 2.78e-09 GO:0048869 cellular developmental process
1.92 6.21e-08 GO:0072358 cardiovascular system development
1.92 6.21e-08 GO:0072359 circulatory system development
1.61 3.54e-07 GO:0022008 neurogenesis
1.63 4.28e-07 GO:0048699 generation of neurons
1.69 1.36e-06 GO:0030182 neuron differentiation
1.65 1.69e-06 GO:2000026 regulation of multicellular organismal development
2.01 5.00e-06 GO:0001501 skeletal system development
1.38 5.24e-06 GO:0048513 organ development
1.79 6.28e-06 GO:0000904 cell morphogenesis involved in differentiation
1.68 1.20e-05 GO:0032989 cellular component morphogenesis
1.64 1.63e-05 GO:0009790 embryo development
1.69 2.28e-05 GO:0000902 cell morphogenesis
2.01 2.91e-05 GO:0001944 vasculature development
1.32 2.95e-05 GO:0048519 negative regulation of biological process
1.82 3.10e-05 GO:0007409 axonogenesis
1.87 3.67e-05 GO:0048598 embryonic morphogenesis
1.33 3.75e-05 GO:0048523 negative regulation of cellular process
1.80 4.35e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
2.67 4.91e-05 GO:0048736 appendage development
2.67 4.91e-05 GO:0060173 limb development
1.67 5.48e-05 GO:0009887 organ morphogenesis
2.70 5.67e-05 GO:0035107 appendage morphogenesis
2.70 5.67e-05 GO:0035108 limb morphogenesis
1.53 7.01e-05 GO:0050793 regulation of developmental process
1.52 8.09e-05 GO:0048468 cell development
2.44 1.00e-04 GO:0007156 homophilic cell adhesion
2.82 1.99e-04 GO:0051271 negative regulation of cellular component movement
1.75 2.15e-04 GO:0048812 neuron projection morphogenesis
1.65 2.21e-04 GO:0048666 neuron development
1.96 2.22e-04 GO:0061061 muscle structure development
2.86 2.23e-04 GO:0048706 embryonic skeletal system development
1.56 2.30e-04 GO:0007155 cell adhesion
1.56 2.30e-04 GO:0022610 biological adhesion
1.61 2.49e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.97 2.56e-04 GO:0001568 blood vessel development
1.51 3.87e-04 GO:0040011 locomotion
1.69 4.65e-04 GO:0031175 neuron projection development
2.83 4.71e-04 GO:0030336 negative regulation of cell migration
2.83 4.71e-04 GO:2000146 negative regulation of cell motility
2.00 6.20e-04 GO:0003002 regionalization
1.86 8.87e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.65 9.96e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.65 1.23e-03 GO:0048858 cell projection morphogenesis
1.68 1.37e-03 GO:0048646 anatomical structure formation involved in morphogenesis
6.37 1.43e-03 GO:0001953 negative regulation of cell-matrix adhesion
1.45 1.66e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.39 1.66e-03 GO:0051239 regulation of multicellular organismal process
2.18 1.72e-03 GO:0009952 anterior/posterior pattern formation
1.84 1.84e-03 GO:0016337 cell-cell adhesion
1.64 1.88e-03 GO:0032990 cell part morphogenesis
2.31 2.22e-03 GO:0048705 skeletal system morphogenesis
1.45 2.48e-03 GO:0042127 regulation of cell proliferation
1.13 2.49e-03 GO:0050794 regulation of cellular process
1.26 2.60e-03 GO:0048522 positive regulation of cellular process
1.74 2.61e-03 GO:0009792 embryo development ending in birth or egg hatching
1.99 2.68e-03 GO:0048514 blood vessel morphogenesis
1.79 3.09e-03 GO:0051093 negative regulation of developmental process
1.69 3.19e-03 GO:0008285 negative regulation of cell proliferation
1.74 3.26e-03 GO:0043009 chordate embryonic development
1.55 3.46e-03 GO:0030030 cell projection organization
1.35 4.07e-03 GO:0009966 regulation of signal transduction
2.54 4.07e-03 GO:0030326 embryonic limb morphogenesis
2.54 4.07e-03 GO:0035113 embryonic appendage morphogenesis
1.33 4.11e-03 GO:0023051 regulation of signaling
1.82 4.76e-03 GO:0051270 regulation of cellular component movement
1.55 4.82e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.24 4.87e-03 GO:0048518 positive regulation of biological process
2.51 5.27e-03 GO:0040013 negative regulation of locomotion
1.87 5.64e-03 GO:0030334 regulation of cell migration
1.21 6.81e-03 GO:0016043 cellular component organization
2.43 7.20e-03 GO:0030323 respiratory tube development
1.84 8.57e-03 GO:2000145 regulation of cell motility
1.51 8.81e-03 GO:0045595 regulation of cell differentiation
2.14 8.94e-03 GO:0045165 cell fate commitment
2.92 9.56e-03 GO:0016202 regulation of striated muscle tissue development
1.51 1.07e-02 GO:0010628 positive regulation of gene expression
2.43 1.11e-02 GO:0030324 lung development
1.19 1.22e-02 GO:0023052 signaling
1.12 1.25e-02 GO:0050789 regulation of biological process
1.73 1.50e-02 GO:0007411 axon guidance
1.43 1.73e-02 GO:0009888 tissue development
2.82 1.83e-02 GO:0048634 regulation of muscle organ development
1.77 1.85e-02 GO:0040012 regulation of locomotion
1.64 1.97e-02 GO:0016477 cell migration
1.95 1.99e-02 GO:0007517 muscle organ development
1.70 2.15e-02 GO:0007389 pattern specification process
1.77 2.55e-02 GO:0035295 tube development
1.72 2.57e-02 GO:0060284 regulation of cell development
1.75 2.69e-02 GO:0030029 actin filament-based process
1.19 2.99e-02 GO:0007165 signal transduction
1.19 3.21e-02 GO:0071840 cellular component organization or biogenesis
2.11 3.83e-02 GO:0060537 muscle tissue development
1.78 3.88e-02 GO:0045596 negative regulation of cell differentiation
1.63 4.12e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.45 4.36e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
2.08 4.39e-02 GO:0050678 regulation of epithelial cell proliferation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.70 7.65e-07 GO:0030054 cell junction
1.92 7.85e-06 GO:0005578 proteinaceous extracellular matrix
1.81 1.67e-05 GO:0031012 extracellular matrix
2.25 8.72e-05 GO:0005912 adherens junction
2.34 5.71e-04 GO:0044420 extracellular matrix part
2.08 7.00e-04 GO:0070161 anchoring junction
1.18 8.24e-04 GO:0005886 plasma membrane
1.18 1.25e-03 GO:0071944 cell periphery
2.31 1.68e-03 GO:0030055 cell-substrate junction
2.28 6.04e-03 GO:0005925 focal adhesion
1.77 1.32e-02 GO:0016323 basolateral plasma membrane
2.17 1.68e-02 GO:0005924 cell-substrate adherens junction
2.32 1.74e-02 GO:0030027 lamellipodium
1.82 1.80e-02 GO:0005911 cell-cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.44 2.80e-04 GO:0001071 nucleic acid binding transcription factor activity
1.44 2.80e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.41 9.89e-04 GO:0030528 transcription regulator activity
1.75 1.26e-03 GO:0003779 actin binding
1.57 1.58e-03 GO:0008092 cytoskeletal protein binding
1.48 4.08e-03 GO:0043565 sequence-specific DNA binding
2.56 6.51e-03 GO:0005089 Rho guanyl-nucleotide exchange factor activity
2.94 1.75e-02 GO:0008013 beta-catenin binding
1.66 1.86e-02 GO:0016563 transcription activator activity
1.10 2.39e-02 GO:0005515 protein binding
1.44 2.48e-02 GO:0005509 calcium ion binding
2.23 4.48e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity