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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HIC1.p2

Z-value: 7.893

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_48235148	10.766	NM_001194986	LOC388630	UPF0632 protein A
chr2_+_9532087	9.189	NM_001039613	IAH1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr2_-_96174502	8.634		DUSP2	dual specificity phosphatase 2
chr13_-_109757442	8.588	NM_001845	COL4A1	collagen, type IV, alpha 1
chr15_+_99237527	8.584	NM_000693	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr13_+_109757593	8.557	NM_001846	COL4A2	collagen, type IV, alpha 2
chr15_-_49174107	8.459		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr9_+_123501186	8.363		DAB2IP	DAB2 interacting protein
chr2_-_98919109	8.239	NM_207362	C2orf55	chromosome 2 open reading frame 55
chr20_-_17459973	8.140	NM_001195	BFSP1	beaded filament structural protein 1, filensin
chr2_-_96174865	8.123	NM_004418	DUSP2	dual specificity phosphatase 2
chr13_-_43259032	7.230	NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr3_+_53504070	7.121	NM_000720 NM_001128839 NM_001128840	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr9_+_17568952	7.007	NM_003026	SH3GL2	SH3-domain GRB2-like 2
chr2_+_238060602	6.663	NM_001042467 NM_024101	MLPH	melanophilin
chr2_+_29191711	6.554	NM_024692	CLIP4	CAP-GLY domain containing linker protein family, member 4
chr1_-_62557559	6.490		KANK4	KN motif and ankyrin repeat domains 4
chr18_+_19523402	6.188		LAMA3	laminin, alpha 3
chr17_-_10042579	5.979	NM_201433	GAS7	growth arrest-specific 7
chr13_-_100866839	5.953		NALCN	sodium leak channel, non-selective
chr17_+_8865547	5.948	NM_004822	NTN1	netrin 1
chr22_-_39964001	5.922		CHADL	chondroadherin-like
chr7_-_81910956	5.725	NM_000722	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr18_-_42590989	5.686	NM_013305	ST8SIA5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr4_+_19864332	5.651	NM_004787	SLIT2	slit homolog 2 (Drosophila)
chr3_-_126414252	5.597	NM_024628	SLC12A8	solute carrier family 12 (potassium/chloride transporters), member 8
chr15_+_99237555	5.572		ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr10_+_116843108	5.562	NM_207303	ATRNL1	attractin-like 1
chr12_-_94708477	5.523		NTN4	netrin 4
chr2_-_112907577	5.442	NM_001164463	RGPD8 RGPD5	RANBP2-like and GRIP domain containing 8 RANBP2-like and GRIP domain containing 5
chr15_+_92575767	5.346		MCTP2	multiple C2 domains, transmembrane 2
chr10_-_128066935	5.334		ADAM12	ADAM metallopeptidase domain 12
chr9_+_115958051	5.312	NM_032888	COL27A1	collagen, type XXVII, alpha 1
chr2_+_23461802	5.308	NM_052920	KLHL29	kelch-like 29 (Drosophila)
chr14_+_85069217	5.258
chr1_-_62557655	5.250	NM_181712	KANK4	KN motif and ankyrin repeat domains 4
chr7_-_27136876	5.247	NM_002141	HOXA4	homeobox A4
chr14_+_92049396	5.207	NM_024832	RIN3	Ras and Rab interactor 3
chr16_-_71639670	5.146	NM_006885	ZFHX3	zinc finger homeobox 3
chr12_+_119562737	5.145	NM_001033677	CABP1	calcium binding protein 1
chr11_+_101485946	5.138	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chrX_+_147389825	5.138	NM_001169122 NM_001169123 NM_001169124 NM_001169125 NM_002025	AFF2	AF4/FMR2 family, member 2
chr10_+_71232281	5.132		COL13A1	collagen, type XIII, alpha 1
chr2_-_224612177	5.126	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr7_-_32076985	5.110	NM_001191056 NM_001191057	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr1_+_17738863	5.091	NM_018125	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr3_+_61522310	5.072		PTPRG	protein tyrosine phosphatase, receptor type, G
chr18_+_19523526	5.036	NM_001127717 NM_198129	LAMA3	laminin, alpha 3
chr18_+_29412538	4.990	NM_030632	ASXL3	additional sex combs like 3 (Drosophila)
chr17_+_26322168	4.947		RNF135	ring finger protein 135
chr7_+_128365226	4.911	NM_001098629 NM_001098630	IRF5	interferon regulatory factor 5
chr10_-_128067001	4.901		ADAM12	ADAM metallopeptidase domain 12
chr6_+_160689355	4.830	NM_021977	SLC22A3	solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr7_-_32077504	4.830	NM_001191059 NM_005020	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr1_-_115682374	4.798	NM_002506	NGF	nerve growth factor (beta polypeptide)
chr1_+_199108705	4.783	NM_005298	GPR25	G protein-coupled receptor 25
chr5_-_58370693	4.782	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr13_-_100866706	4.745	NM_052867	NALCN	sodium leak channel, non-selective
chr9_+_86473273	4.715	NM_001018064 NM_006180	NTRK2	neurotrophic tyrosine kinase, receptor, type 2
chr15_+_66658626	4.672	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr3_+_11171213	4.664	NM_001098212	HRH1	histamine receptor H1
chr17_+_26322081	4.657	NM_001184992 NM_032322 NM_197939	RNF135	ring finger protein 135
chr11_-_45643711	4.655	NM_003654	CHST1	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr18_-_6404900	4.646	NM_173464	L3MBTL4	l(3)mbt-like 4 (Drosophila)
chr15_+_31390454	4.642	NM_001036	RYR3	ryanodine receptor 3
chr12_-_26166485	4.628		BHLHE41	basic helix-loop-helix family, member e41
chr15_-_91433165	4.604	NM_020211	RGMA	RGM domain family, member A
chr5_+_2805261	4.590	NM_178569	C5orf38	chromosome 5 open reading frame 38
chr18_-_7107757	4.588	NM_005559	LAMA1	laminin, alpha 1
chr3_+_141136691	4.577	NM_022131	CLSTN2	calsyntenin 2
chr2_+_238200922	4.538	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr4_+_95898098	4.483	NM_001203	BMPR1B	bone morphogenetic protein receptor, type IB
chr12_-_102413875	4.475	NM_198521 NM_001099336	C12orf42	chromosome 12 open reading frame 42
chr2_+_109112428	4.455	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr8_-_41286088	4.455	NM_003012	SFRP1	secreted frizzled-related protein 1
chr13_-_20193739	4.449
chr7_+_128365482	4.434	NM_032643	IRF5	interferon regulatory factor 5
chr4_-_141896920	4.425	NM_015130	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)
chr6_+_137285071	4.421	NM_001008783	SLC35D3	solute carrier family 35, member D3
chr15_-_81412354	4.379	NM_004839 NM_199330 NM_199331 NM_199332	HOMER2	homer homolog 2 (Drosophila)
chr3_+_53503626	4.371		CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr7_-_107089387	4.364		LOC286002	hypothetical LOC286002
chr9_-_21549696	4.352		LOC554202	hypothetical LOC554202
chr17_+_52026058	4.350	NM_005450	NOG	noggin
chr12_+_3056781	4.320	NM_001168320 NM_006675	TSPAN9	tetraspanin 9
chr4_-_122063118	4.270	NM_018699	PRDM5	PR domain containing 5
chr7_-_107883929	4.252	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr10_+_128583984	4.249	NM_001380	DOCK1	dedicator of cytokinesis 1
chr13_+_95541093	4.195	NM_153456	HS6ST3	heparan sulfate 6-O-sulfotransferase 3
chr20_+_60810610	4.195	NM_002531	NTSR1	neurotensin receptor 1 (high affinity)
chr8_+_17398940	4.181	NM_001008539	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr8_+_22492586	4.172		PDLIM2	PDZ and LIM domain 2 (mystique)
chr2_+_120820140	4.159	NM_002193	INHBB	inhibin, beta B
chr3_+_61522219	4.146	NM_002841	PTPRG	protein tyrosine phosphatase, receptor type, G
chr7_-_44331544	4.143	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr12_-_94708641	4.131	NM_021229	NTN4	netrin 4
chr5_-_2804768	4.119	NM_001134222 NM_033267	IRX2	iroquois homeobox 2
chr11_+_75056343	4.074
chr14_+_72773957	4.064	NM_173462	NDRG2 PAPLN	NDRG family member 2 papilin, proteoglycan-like sulfated glycoprotein
chr15_-_81744469	4.060	NM_001717	BNC1	basonuclin 1
chr13_+_97593711	4.048		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr16_-_17472238	4.045	NM_022166	XYLT1	xylosyltransferase I
chr20_-_24986501	4.044		ACSS1	acyl-CoA synthetase short-chain family member 1
chr6_+_147871477	4.043	NM_001030060	SAMD5	sterile alpha motif domain containing 5
chr14_+_105012106	4.029	NM_001312	CRIP2	cysteine-rich protein 2
chr14_+_58174489	4.026	NM_001079520 NM_016651	DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
chr7_-_81910740	4.020		CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr1_+_237616457	4.000		CHRM3	cholinergic receptor, muscarinic 3
chr12_+_20413445	3.970	NM_000921	PDE3A	phosphodiesterase 3A, cGMP-inhibited
chr6_-_170441493	3.961	NM_005618	DLL1	delta-like 1 (Drosophila)
chr7_+_48041632	3.957	NM_001100159	C7orf57	chromosome 7 open reading frame 57
chr6_+_170441715	3.943		FAM120B	family with sequence similarity 120B
chr10_-_62163083	3.941		ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr8_+_27547379	3.936	NM_016240 NM_182826	SCARA3	scavenger receptor class A, member 3
chr2_+_28887203	3.925	NM_001142634 NM_182756	SPDYA	speedy homolog A (Xenopus laevis)
chr5_-_146869613	3.923		DPYSL3	dihydropyrimidinase-like 3
chr11_-_112851051	3.911	NM_000795 NM_016574	DRD2	dopamine receptor D2
chr9_-_71476917	3.911	NM_001163	APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1
chr5_-_146869811	3.902	NM_001197294	DPYSL3	dihydropyrimidinase-like 3
chr21_-_43671355	3.891	NM_173354	SIK1	salt-inducible kinase 1
chr8_+_38733913	3.883		TACC1	transforming, acidic coiled-coil containing protein 1
chr18_+_42168180	3.848	NM_152470	C18orf23 RNF165	chromosome 18 open reading frame 23 ring finger protein 165
chr2_+_95376494	3.845	NM_001034914	KCNIP3	Kv channel interacting protein 3, calsenilin
chr10_-_128067052	3.840		ADAM12	ADAM metallopeptidase domain 12
chr11_-_44928803	3.827	NM_001076787 NM_006034	TP53I11	tumor protein p53 inducible protein 11
chr4_+_79197747	3.791	NM_001166133 NM_025074	FRAS1	Fraser syndrome 1
chr22_+_47263919	3.788	NM_001082967	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr21_+_25856311	3.788		MIR155HG	MIR155 host gene (non-protein coding)
chr18_-_5620629	3.786		EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr9_-_135847106	3.775	NM_001134398 NM_003371	VAV2	vav 2 guanine nucleotide exchange factor
chr6_+_1257674	3.757	NM_033260	FOXQ1	forkhead box Q1
chr8_+_32525269	3.751	NM_001160002 NM_001160004 NM_001160005 NM_001160007 NM_001160008 NM_004495 NM_013956 NM_013957 NM_013958 NM_013960 NM_013964	NRG1	neuregulin 1
chr5_+_129268352	3.751	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr9_-_88751923	3.750	NM_002048	GAS1	growth arrest-specific 1
chr13_-_109236897	3.750	NM_003749	IRS2	insulin receptor substrate 2
chr17_-_6400470	3.739	NM_001165966 NM_031220	PITPNM3	PITPNM family member 3
chr4_+_4439705	3.729		D4S234E	DNA segment on chromosome 4 (unique) 234 expressed sequence
chr1_+_234372454	3.725	NM_003272	GPR137B	G protein-coupled receptor 137B
chr2_-_127580975	3.720	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chr19_-_1188840	3.715	NM_152769	C19orf26	chromosome 19 open reading frame 26
chr1_-_85235210	3.705	NM_153259	MCOLN2	mucolipin 2
chr13_-_94162249	3.698	NM_007084	SOX21	SRY (sex determining region Y)-box 21
chr4_-_24523605	3.675	NM_001130726	CCDC149	coiled-coil domain containing 149
chr3_+_44878380	3.667	NM_144638	TMEM42	transmembrane protein 42
chr11_-_61104866	3.650	NM_004200	SYT7	synaptotagmin VII
chr11_+_126378507	3.648		NCRNA00288	non-protein coding RNA 288
chr8_-_70909754	3.646	NM_030958	SLCO5A1	solute carrier organic anion transporter family, member 5A1
chr16_-_84342129	3.619	NM_206967	C16orf74	chromosome 16 open reading frame 74
chr18_-_29412148	3.619
chr4_+_15388985	3.617	NM_001775	CD38	CD38 molecule
chr18_+_42167904	3.600		RNF165	ring finger protein 165
chr15_+_82113813	3.596	NM_207517	ADAMTSL3	ADAMTS-like 3
chr18_+_10444625	3.594		APCDD1	adenomatosis polyposis coli down-regulated 1
chr12_-_29827952	3.562	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr6_-_18230829	3.561	NM_198586	NHLRC1	NHL repeat containing 1
chr7_-_27162688	3.552	NM_006896	HOXA7	homeobox A7
chr15_-_64333048	3.544	NM_032445	MEGF11	multiple EGF-like-domains 11
chr2_+_10779191	3.543	NM_001039362 NM_144583	ATP6V1C2	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
chr2_+_100802923	3.534	NM_002518	NPAS2	neuronal PAS domain protein 2
chr6_+_72055197	3.529	NM_024576	OGFRL1	opioid growth factor receptor-like 1
chr1_-_234294997	3.517		NID1	nidogen 1
chr4_+_4439618	3.506		D4S234E	DNA segment on chromosome 4 (unique) 234 expressed sequence
chr11_-_9069668	3.505	NM_001170690 NM_020974	SCUBE2	signal peptide, CUB domain, EGF-like 2
chr3_-_191522886	3.489	NM_021101	CLDN1	claudin 1
chr19_-_5291700	3.487	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr20_+_56701224	3.486	NM_024663	NPEPL1	aminopeptidase-like 1
chr4_+_77829634	3.464		SHROOM3	shroom family member 3
chr6_-_166641860	3.455	NM_175922	PRR18	proline rich 18
chr5_+_76542461	3.451	NM_001029851 NM_001029852 NM_001029853 NM_001029854 NM_003719	PDE8B	phosphodiesterase 8B
chr2_-_101370355	3.443	NM_153836	CREG2	cellular repressor of E1A-stimulated genes 2
chr3_+_9826643	3.425	NM_001025930	TTLL3	tubulin tyrosine ligase-like family, member 3
chr20_-_4177519	3.415	NM_000678	ADRA1D	adrenergic, alpha-1D-, receptor
chr6_-_89884324	3.407	NM_080743	SRSF12	serine/arginine-rich splicing factor 12
chr13_+_32488477	3.399	NM_004795	KL	klotho
chr3_+_71885890	3.396	NM_018971	GPR27	G protein-coupled receptor 27
chr4_+_4439750	3.393		D4S234E	DNA segment on chromosome 4 (unique) 234 expressed sequence
chr15_+_77511912	3.381	NM_015206	KIAA1024	KIAA1024
chr18_-_68361742	3.369		CBLN2	cerebellin 2 precursor
chr9_+_128128913	3.364	NM_001011703 NM_033446	FAM125B	family with sequence similarity 125, member B
chr10_-_118022707	3.354	NM_001145453	GFRA1	GDNF family receptor alpha 1
chr15_+_38923914	3.354	NM_001032367	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr14_+_89597860	3.350	NM_022054	KCNK13	potassium channel, subfamily K, member 13
chr3_+_198214173	3.349		LOC100507057 MFI2	hypothetical LOC100507057 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr9_-_38414422	3.342	NM_001007563	IGFBPL1	insulin-like growth factor binding protein-like 1
chr11_+_120828058	3.337	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr14_+_95575319	3.335		C14orf132	chromosome 14 open reading frame 132
chr8_-_125809559	3.325		MTSS1	metastasis suppressor 1
chr17_-_74432671	3.319		TIMP2	TIMP metallopeptidase inhibitor 2
chr6_-_170442090	3.317
chr4_+_156899575	3.317	NM_000857	GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr19_-_11234117	3.315	NM_020812	DOCK6	dedicator of cytokinesis 6
chr11_+_131285747	3.312	NM_001144058 NM_001144059 NM_016522	NTM	neurotrimin
chr10_-_30065760	3.308		SVIL	supervillin
chr14_-_87859284	3.302	NM_138317	KCNK10	potassium channel, subfamily K, member 10
chr11_+_65815940	3.297	NM_153266	TMEM151A	transmembrane protein 151A
chr12_-_62348506	3.285	NM_173812	DPY19L2	dpy-19-like 2 (C. elegans)
chr4_+_151218862	3.281	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr1_-_111548440	3.280		DENND2D	DENN/MADD domain containing 2D
chr11_-_78829342	3.266	NM_001098816	ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)
chr13_+_97593469	3.236		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.51	3.81e-26	GO:0007399	nervous system development
1.65	1.45e-23	GO:0048699	generation of neurons
1.63	2.43e-23	GO:0022008	neurogenesis
1.29	2.93e-22	GO:0007275	multicellular organismal development
1.26	5.61e-21	GO:0032502	developmental process
1.37	7.24e-20	GO:0030154	cell differentiation
1.36	9.33e-20	GO:0048869	cellular developmental process
1.80	1.08e-19	GO:0000904	cell morphogenesis involved in differentiation
1.44	1.73e-19	GO:0009653	anatomical structure morphogenesis
1.66	6.43e-19	GO:0030182	neuron differentiation
1.71	8.09e-19	GO:0000902	cell morphogenesis
1.30	9.24e-19	GO:0048731	system development
1.28	3.62e-18	GO:0048856	anatomical structure development
1.40	1.13e-17	GO:0023051	regulation of signaling
1.80	1.93e-17	GO:0048812	neuron projection morphogenesis
1.80	2.75e-17	GO:0048667	cell morphogenesis involved in neuron differentiation
1.69	8.59e-17	GO:0048666	neuron development
1.65	1.12e-16	GO:0032989	cellular component morphogenesis
1.73	1.22e-16	GO:0048858	cell projection morphogenesis
1.53	1.59e-16	GO:0048468	cell development
1.73	1.85e-16	GO:0032990	cell part morphogenesis
1.73	2.26e-16	GO:0031175	neuron projection development
1.79	3.90e-16	GO:0007409	axonogenesis
1.63	1.10e-15	GO:0030030	cell projection organization
1.40	4.03e-15	GO:0009966	regulation of signal transduction
1.14	8.07e-13	GO:0050794	regulation of cellular process
1.78	4.35e-12	GO:0007411	axon guidance
1.19	3.67e-10	GO:0023052	signaling
1.74	5.19e-10	GO:0060284	regulation of cell development
1.58	5.55e-10	GO:0007417	central nervous system development
1.11	1.23e-09	GO:0065007	biological regulation
1.12	1.70e-09	GO:0050789	regulation of biological process
1.72	8.30e-09	GO:0048729	tissue morphogenesis
1.66	1.64e-08	GO:0007389	pattern specification process
1.27	2.33e-08	GO:0048513	organ development
1.64	2.34e-08	GO:0007420	brain development
1.44	2.71e-08	GO:2000026	regulation of multicellular organismal development
1.36	5.54e-08	GO:0010646	regulation of cell communication
1.07	6.40e-08	GO:0009987	cellular process
1.18	9.51e-08	GO:0007165	signal transduction
1.26	1.30e-07	GO:0048583	regulation of response to stimulus
1.44	1.40e-07	GO:0045595	regulation of cell differentiation
1.31	1.52e-07	GO:0035556	intracellular signal transduction
1.60	2.70e-07	GO:0051056	regulation of small GTPase mediated signal transduction
1.69	2.78e-07	GO:0035295	tube development
1.37	3.55e-07	GO:0050793	regulation of developmental process
1.58	7.05e-07	GO:0048598	embryonic morphogenesis
1.35	8.75e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.71	9.46e-07	GO:0050767	regulation of neurogenesis
1.79	1.10e-06	GO:0045664	regulation of neuron differentiation
1.51	1.32e-06	GO:0048646	anatomical structure formation involved in morphogenesis
1.66	1.47e-06	GO:0051960	regulation of nervous system development
1.45	1.56e-06	GO:0009887	organ morphogenesis
1.63	1.86e-06	GO:0022603	regulation of anatomical structure morphogenesis
1.72	2.55e-06	GO:0002009	morphogenesis of an epithelium
1.21	4.14e-06	GO:0048519	negative regulation of biological process
1.40	4.51e-06	GO:0009790	embryo development
1.94	4.52e-06	GO:0030111	regulation of Wnt receptor signaling pathway
1.36	5.41e-06	GO:0009888	tissue development
1.78	7.30e-06	GO:0035239	tube morphogenesis
1.21	7.32e-06	GO:0048523	negative regulation of cellular process
1.52	9.41e-06	GO:0009968	negative regulation of signal transduction
1.28	9.57e-06	GO:0051239	regulation of multicellular organismal process
1.68	1.32e-05	GO:0003002	regionalization
2.02	1.41e-05	GO:0010720	positive regulation of cell development
1.49	1.61e-05	GO:0023057	negative regulation of signaling
1.49	1.99e-05	GO:0010648	negative regulation of cell communication
1.41	2.39e-05	GO:0045893	positive regulation of transcription, DNA-dependent
1.84	2.50e-05	GO:0060562	epithelial tube morphogenesis
1.23	2.87e-05	GO:0007166	cell surface receptor linked signaling pathway
2.17	3.84e-05	GO:0016331	morphogenesis of embryonic epithelium
1.46	5.59e-05	GO:0072358	cardiovascular system development
1.46	5.59e-05	GO:0072359	circulatory system development
1.88	6.39e-05	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.33	7.31e-05	GO:0040011	locomotion
1.38	7.59e-05	GO:0010628	positive regulation of gene expression
2.10	7.73e-05	GO:0060485	mesenchyme development
1.13	9.11e-05	GO:0051716	cellular response to stimulus
1.87	9.60e-05	GO:0022604	regulation of cell morphogenesis
1.62	1.04e-04	GO:0046578	regulation of Ras protein signal transduction
1.43	1.41e-04	GO:0048585	negative regulation of response to stimulus
2.25	1.51e-04	GO:0072175	epithelial tube formation
1.37	1.67e-04	GO:0007167	enzyme linked receptor protein signaling pathway
2.08	2.04e-04	GO:0021953	central nervous system neuron differentiation
1.53	2.07e-04	GO:0001501	skeletal system development
1.49	2.52e-04	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.36	3.40e-04	GO:0051254	positive regulation of RNA metabolic process
2.23	3.43e-04	GO:0001838	embryonic epithelial tube formation
2.11	4.85e-04	GO:0050770	regulation of axonogenesis
1.46	4.87e-04	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.73	6.15e-04	GO:0006813	potassium ion transport
1.82	6.32e-04	GO:0010975	regulation of neuron projection development
1.42	6.52e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.65	7.70e-04	GO:0032582	negative regulation of gene-specific transcription
2.14	9.18e-04	GO:0035148	tube formation
1.40	9.78e-04	GO:0006935	chemotaxis
1.40	9.78e-04	GO:0042330	taxis
1.68	1.17e-03	GO:0030900	forebrain development
1.50	1.21e-03	GO:0051093	negative regulation of developmental process
1.55	1.40e-03	GO:0045596	negative regulation of cell differentiation
1.38	1.52e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.42	2.13e-03	GO:0032583	regulation of gene-specific transcription
1.16	2.69e-03	GO:0071842	cellular component organization at cellular level
1.37	2.80e-03	GO:0051253	negative regulation of RNA metabolic process
2.32	2.83e-03	GO:0001704	formation of primary germ layer
1.96	2.99e-03	GO:0021915	neural tube development
1.30	3.52e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.96	3.78e-03	GO:0050769	positive regulation of neurogenesis
2.23	3.79e-03	GO:0001841	neural tube formation
1.68	4.37e-03	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.27	5.14e-03	GO:0042127	regulation of cell proliferation
1.10	5.39e-03	GO:0032501	multicellular organismal process
1.91	5.72e-03	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.69	5.99e-03	GO:0001655	urogenital system development
1.26	6.06e-03	GO:0007154	cell communication
1.15	6.07e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37	6.22e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.16	7.66e-03	GO:0048522	positive regulation of cellular process
2.31	7.91e-03	GO:0014020	primary neural tube formation
1.86	8.14e-03	GO:0021537	telencephalon development
1.33	8.21e-03	GO:0010629	negative regulation of gene expression
1.67	8.75e-03	GO:0031344	regulation of cell projection organization
1.48	9.01e-03	GO:0001944	vasculature development
2.34	9.38e-03	GO:0001843	neural tube closure
1.98	9.61e-03	GO:0048762	mesenchymal cell differentiation
1.30	1.05e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.48	1.10e-02	GO:0007423	sensory organ development
1.38	1.18e-02	GO:0051094	positive regulation of developmental process
1.31	1.19e-02	GO:0009890	negative regulation of biosynthetic process
1.84	1.21e-02	GO:0051216	cartilage development
1.32	1.22e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.15	1.23e-02	GO:0048518	positive regulation of biological process
1.16	1.25e-02	GO:0006355	regulation of transcription, DNA-dependent
1.42	1.27e-02	GO:0009792	embryo development ending in birth or egg hatching
1.14	1.29e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.32	1.41e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25	1.50e-02	GO:0009605	response to external stimulus
1.64	1.67e-02	GO:0048562	embryonic organ morphogenesis
1.16	1.72e-02	GO:0051252	regulation of RNA metabolic process
1.32	1.72e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.09	1.75e-02	GO:0043407	negative regulation of MAP kinase activity
1.41	1.84e-02	GO:0043009	chordate embryonic development
2.28	1.85e-02	GO:0060606	tube closure
1.12	1.93e-02	GO:0016043	cellular component organization
1.43	1.99e-02	GO:0045597	positive regulation of cell differentiation
1.28	2.09e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12	2.21e-02	GO:0051179	localization
1.76	2.28e-02	GO:0072001	renal system development
1.31	2.37e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.30	2.62e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.51	2.74e-02	GO:0048568	embryonic organ development
1.40	3.06e-02	GO:0060429	epithelium development
1.96	3.08e-02	GO:0014031	mesenchymal cell development
1.87	3.41e-02	GO:0030178	negative regulation of Wnt receptor signaling pathway
1.39	3.49e-02	GO:0007264	small GTPase mediated signal transduction
1.75	3.67e-02	GO:0001822	kidney development
1.12	3.73e-02	GO:0031323	regulation of cellular metabolic process
1.93	3.81e-02	GO:0001657	ureteric bud development
1.85	4.00e-02	GO:0007369	gastrulation
1.55	4.19e-02	GO:0048732	gland development
1.90	4.62e-02	GO:0010721	negative regulation of cell development
1.90	4.62e-02	GO:2000027	regulation of organ morphogenesis
2.48	4.80e-02	GO:0021954	central nervous system neuron development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.23	3.15e-08	GO:0044459	plasma membrane part
1.44	1.96e-07	GO:0030054	cell junction
1.53	3.48e-07	GO:0045202	synapse
1.56	8.00e-06	GO:0044456	synapse part
1.71	1.78e-04	GO:0005912	adherens junction
1.45	2.06e-04	GO:0031012	extracellular matrix
1.07	5.14e-04	GO:0016020	membrane
1.64	7.83e-04	GO:0070161	anchoring junction
1.68	2.14e-03	GO:0034703	cation channel complex
1.48	6.96e-03	GO:0016323	basolateral plasma membrane
1.22	1.28e-02	GO:0005794	Golgi apparatus
1.54	1.60e-02	GO:0043025	neuronal cell body
1.58	1.65e-02	GO:0045211	postsynaptic membrane
1.35	1.71e-02	GO:0043005	neuron projection
1.76	1.80e-02	GO:0008076	voltage-gated potassium channel complex
1.76	1.80e-02	GO:0034705	potassium channel complex
1.39	2.26e-02	GO:0005578	proteinaceous extracellular matrix
1.51	2.58e-02	GO:0044297	cell body
1.70	2.61e-02	GO:0005925	focal adhesion
1.18	4.21e-02	GO:0031226	intrinsic to plasma membrane
1.75	4.69e-02	GO:0014069	postsynaptic density

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.57	1.11e-09	GO:0030695	GTPase regulator activity
1.56	1.25e-09	GO:0060589	nucleoside-triphosphatase regulator activity
1.37	3.42e-09	GO:0001071	nucleic acid binding transcription factor activity
1.37	3.42e-09	GO:0003700	sequence-specific DNA binding transcription factor activity
1.32	1.34e-06	GO:0030528	transcription regulator activity
1.36	2.32e-05	GO:0043565	sequence-specific DNA binding
1.85	3.11e-05	GO:0005267	potassium channel activity
1.54	8.37e-05	GO:0005083	small GTPase regulator activity
1.72	5.48e-04	GO:0022843	voltage-gated cation channel activity
1.62	6.55e-04	GO:0005244	voltage-gated ion channel activity
1.62	6.55e-04	GO:0022832	voltage-gated channel activity
1.86	8.65e-04	GO:0005249	voltage-gated potassium channel activity
1.88	1.18e-03	GO:0005088	Ras guanyl-nucleotide exchange factor activity
1.46	1.42e-03	GO:0016563	transcription activator activity
1.65	1.47e-03	GO:0005085	guanyl-nucleotide exchange factor activity
1.41	2.19e-03	GO:0008047	enzyme activator activity
1.43	2.49e-03	GO:0042578	phosphoric ester hydrolase activity
1.55	3.43e-03	GO:0000975	regulatory region DNA binding
1.55	3.43e-03	GO:0001067	regulatory region nucleic acid binding
1.55	3.43e-03	GO:0044212	transcription regulatory region DNA binding
1.49	3.58e-03	GO:0005096	GTPase activator activity
1.48	3.72e-03	GO:0005261	cation channel activity
1.11	4.24e-03	GO:0046872	metal ion binding
1.11	5.87e-03	GO:0043169	cation binding
1.11	6.54e-03	GO:0043167	ion binding
1.54	8.09e-03	GO:0010843	promoter binding
1.42	1.40e-02	GO:0022836	gated channel activity
1.85	2.88e-02	GO:0005089	Rho guanyl-nucleotide exchange factor activity
1.73	2.88e-02	GO:0016566	specific transcriptional repressor activity
1.56	3.06e-02	GO:0004721	phosphoprotein phosphatase activity
1.22	3.38e-02	GO:0030234	enzyme regulator activity
1.04	3.99e-02	GO:0005488	binding