Motif ID: KLF12.p2

Z-value: 3.094


Transcription factors associated with KLF12.p2:

Gene SymbolEntrez IDGene Name
KLF12 11278 Kruppel-like factor 12

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF12chr13_-_73605914-0.175.2e-01Click!


Activity profile for motif KLF12.p2.

activity profile for motif KLF12.p2


Sorted Z-values histogram for motif KLF12.p2

Sorted Z-values for motif KLF12.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF12.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_1580504 2.523 WDR81
WD repeat domain 81
chr12_+_52665196 2.110 NM_017409
HOXC10
homeobox C10
chr1_+_109594163 1.731 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr11_+_65164767 1.713 SIPA1
signal-induced proliferation-associated 1
chr16_+_27320983 1.461 NM_181078
NM_181079
IL21R

interleukin 21 receptor

chr5_+_60663842 1.456 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr2_+_104837004 1.420


chr11_+_120966280 1.398 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr16_+_31132842 1.395 NM_001008274
TRIM72
tripartite motif containing 72
chr19_-_7840806 1.366 FLJ22184
hypothetical protein FLJ22184
chr5_-_176868483 1.320 DOK3
docking protein 3
chr2_+_219453487 1.313 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr11_+_65164963 1.268


chr1_+_157441824 1.261 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr17_-_34084682 1.253 NM_001130677
C17orf96
chromosome 17 open reading frame 96
chr16_-_30301357 1.239 SEPT1
septin 1
chr11_+_66381451 1.234 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr8_-_145609737 1.217 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr9_-_122728993 1.193 NM_005658
TRAF1
TNF receptor-associated factor 1
chr17_+_35853177 1.185 NM_001552
IGFBP4
insulin-like growth factor binding protein 4
chr5_-_176869943 1.174 NM_001144875
NM_001144876
DOK3

docking protein 3

chr1_-_38285033 1.136 NM_002699
POU3F1
POU class 3 homeobox 1
chr17_-_8474733 1.105 NM_005964
MYH10
myosin, heavy chain 10, non-muscle
chr5_-_176869463 1.100 NM_024872
DOK3
docking protein 3
chr1_-_200396328 1.099 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr15_-_72513311 1.094 NM_001146029
NM_003612
SEMA7A

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

chr12_+_56135353 1.090 NM_031479
INHBE
inhibin, beta E
chr5_-_169657395 1.083 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_-_35331435 1.069 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr6_+_31662454 1.043 NM_205837
LST1
leukocyte specific transcript 1
chr8_+_11388918 1.042 NM_001715
BLK
B lymphoid tyrosine kinase
chr15_-_81146188 1.039 AP3B2
adaptor-related protein complex 3, beta 2 subunit
chr22_-_28992787 1.028 NM_020530
OSM
oncostatin M
chr11_-_110755112 1.016 POU2AF1
POU class 2 associating factor 1
chr20_-_31771550 1.014 NM_007238
NM_183397
PXMP4

peroxisomal membrane protein 4, 24kDa

chr12_-_53064723 1.010 NM_015481
ZNF385A
zinc finger protein 385A
chr22_-_39189369 1.009 MKL1
megakaryoblastic leukemia (translocation) 1
chr21_-_46428728 1.009 C21orf56
chromosome 21 open reading frame 56
chr1_+_158636987 1.007 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr16_-_30301634 0.997 NM_052838
SEPT1
septin 1
chr12_+_79625538 0.994 NM_002469
MYF6
myogenic factor 6 (herculin)
chr1_-_200396354 0.993 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr17_+_23723220 0.987 SARM1
sterile alpha and TIR motif containing 1
chr22_+_18499354 0.984 NM_001185024
NM_013373
ZDHHC8

zinc finger, DHHC-type containing 8

chr22_+_20715340 0.965


chr7_-_132371208 0.958 EEF1G
eukaryotic translation elongation factor 1 gamma
chr7_+_100111712 0.957 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr16_-_66535923 0.956 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr1_+_63561632 0.956 FOXD3
forkhead box D3
chr11_+_118259684 0.948 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr21_-_46428788 0.942 NM_001142854
NM_032261
C21orf56

chromosome 21 open reading frame 56

chr11_-_47356479 0.941 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr9_+_115367122 0.940 NM_134427
RGS3
regulator of G-protein signaling 3
chr19_+_54530512 0.938 CD37
CD37 molecule
chr21_-_46428768 0.928 C21orf56
chromosome 21 open reading frame 56
chr16_+_29728932 0.917 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_-_53064565 0.917 ZNF385A
zinc finger protein 385A
chr11_-_47356562 0.915 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr5_-_169657312 0.911 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_+_23723180 0.907 SARM1
sterile alpha and TIR motif containing 1
chr6_+_31661934 0.904 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr5_+_137829077 0.902 NM_001964
EGR1
early growth response 1
chrX_+_67965517 0.898 NM_004429
EFNB1
ephrin-B1
chr19_+_6723705 0.897 NM_005428
VAV1
vav 1 guanine nucleotide exchange factor
chr1_+_6767968 0.896 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr12_+_115481568 0.887 NM_001085481
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr5_+_131733252 0.885 NM_003060
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr7_-_99871981 0.876 NM_145030
C7orf47
chromosome 7 open reading frame 47
chr19_-_43608641 0.871 NM_001146202
NM_001146203
NM_001146204
NM_001146205
NM_001146206
NM_001146207
NM_170604
RASGRP4






RAS guanyl releasing protein 4






chr19_+_54530546 0.866 CD37
CD37 molecule
chr19_+_54530458 0.865 CD37
CD37 molecule
chr6_-_41781655 0.864 TFEB
transcription factor EB
chr19_+_54530497 0.863 CD37
CD37 molecule
chrX_-_152889815 0.863 NM_005334
HCFC1
host cell factor C1 (VP16-accessory protein)
chr17_+_1612092 0.860 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr20_-_3713509 0.860 CENPB
centromere protein B, 80kDa
chr16_+_2959342 0.860 NM_152341
PAQR4
progestin and adipoQ receptor family member IV
chr7_-_75461868 0.856 TMEM120A
transmembrane protein 120A
chr5_-_176869440 0.855 DOK3
docking protein 3
chr5_-_169657192 0.848 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_-_110755366 0.845 NM_006235
POU2AF1
POU class 2 associating factor 1
chr19_+_54530485 0.841 NM_001040031
NM_001774
CD37

CD37 molecule

chr12_+_6930815 0.828 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr17_-_59131210 0.825 NM_030576
LIMD2
LIM domain containing 2
chr16_+_2959362 0.824 PAQR4
progestin and adipoQ receptor family member IV
chr1_-_1840564 0.823 NM_178545
TMEM52
transmembrane protein 52
chr19_+_6723801 0.821


chr1_+_159943385 0.814 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr17_-_5078773 0.813 NM_207103
C17orf87
chromosome 17 open reading frame 87
chr16_+_28413421 0.812 NM_018690
APOBR
apolipoprotein B receptor
chr1_+_199108705 0.804 NM_005298
GPR25
G protein-coupled receptor 25
chr1_+_63561317 0.802 NM_012183
FOXD3
forkhead box D3
chr1_+_154386358 0.800 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_+_162845 0.799 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr6_-_11490487 0.796 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr17_+_1612031 0.796 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_+_6915698 0.791


chr1_+_157441133 0.790 NM_002036
DARC
Duffy blood group, chemokine receptor
chr2_-_73373956 0.787 NM_001965
EGR4
early growth response 4
chr9_+_138991775 0.783 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr11_-_47356642 0.781 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr11_-_57173823 0.779 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr17_+_1612056 0.778 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr1_+_25816545 0.777 NM_020379
MAN1C1
mannosidase, alpha, class 1C, member 1
chr2_-_220144254 0.774 OBSL1
obscurin-like 1
chr11_-_47356672 0.774 NM_001080547
NM_003120
SPI1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

chr7_+_149699185 0.773 NM_014374
REPIN1
replication initiator 1
chr11_+_59902530 0.773 NM_021201
NM_206938
NM_206939
NM_206940
MS4A7



membrane-spanning 4-domains, subfamily A, member 7



chr14_-_105245959 0.772 IGHA1
immunoglobulin heavy constant alpha 1
chr17_+_23723113 0.766 NM_015077
SARM1
sterile alpha and TIR motif containing 1
chr17_-_40839082 0.765 NM_001159330
ARHGAP27
Rho GTPase activating protein 27
chr19_-_51081147 0.764 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr9_-_138387903 0.762 CARD9
caspase recruitment domain family, member 9
chrX_-_154146930 0.762 NM_171998
RAB39B
RAB39B, member RAS oncogene family
chr17_-_35975227 0.760 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr11_+_63864263 0.760 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr7_-_75461814 0.753 TMEM120A
transmembrane protein 120A
chr1_-_201321711 0.752 MYOG
myogenin (myogenic factor 4)
chr6_-_166641860 0.746 NM_175922
PRR18
proline rich 18
chr2_-_25390266 0.745 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr1_+_159817752 0.745 NM_201563
FCGR2C
Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr17_-_45617899 0.745 COL1A1
collagen, type I, alpha 1
chr17_-_71352090 0.743 UNC13D
unc-13 homolog D (C. elegans)
chr16_-_10183244 0.739 NM_001134408
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr7_+_101715137 0.737 SH2B2
SH2B adaptor protein 2
chr5_+_155686333 0.736 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr21_-_46849413 0.732 NM_006272
S100B
S100 calcium binding protein B
chr10_-_105410840 0.730


chr17_-_1029758 0.723 NM_021962
ABR
active BCR-related gene
chr22_+_23153529 0.718 NM_000675
ADORA2A
adenosine A2a receptor
chr16_+_2450081 0.716 NM_025108
C16orf59
chromosome 16 open reading frame 59
chr17_-_34607257 0.714 NM_000723
NM_199247
NM_199248
CACNB1


calcium channel, voltage-dependent, beta 1 subunit


chrX_+_49013424 0.710 PPP1R3F
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr2_+_232281491 0.708 PTMA
prothymosin, alpha
chr7_+_149657810 0.708 NM_138434
C7orf29
chromosome 7 open reading frame 29
chr1_+_199259664 0.708


chr19_-_50975121 0.705


chr17_-_59131194 0.705 LIMD2
LIM domain containing 2
chr6_-_166716353 0.704 BRP44L
brain protein 44-like
chr11_-_64269501 0.702 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr1_+_159959072 0.700 NM_001002901
FCRLB
Fc receptor-like B
chr19_-_60557875 0.698 NM_144613
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr16_-_66535457 0.698 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr10_+_50177192 0.697 NM_001135196
NM_199459
C10orf71

chromosome 10 open reading frame 71

chr8_-_145132582 0.694 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chr11_+_59902598 0.694 MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr8_-_145119627 0.693 NM_201378
PLEC
plectin
chr9_+_138991835 0.692 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr9_+_92629525 0.689 NM_001174167
SYK
spleen tyrosine kinase
chr5_-_149515331 0.689 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr1_+_1157485 0.688 NM_080605
B3GALT6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr1_+_202000906 0.681 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr5_-_39238818 0.677 FYB
FYN binding protein
chr5_+_137829065 0.677 EGR1
early growth response 1
chr15_+_38437703 0.676 NM_033510
DISP2
dispatched homolog 2 (Drosophila)
chr17_+_43127628 0.675 NM_014726
TBKBP1
TBK1 binding protein 1
chr6_+_152168500 0.673 NM_001122741
ESR1
estrogen receptor 1
chr6_+_137285071 0.673 NM_001008783
SLC35D3
solute carrier family 35, member D3
chr11_+_64737886 0.672 NM_001004326
SLC22A20
solute carrier family 22, member 20
chr15_+_38550451 0.669 NM_130468
CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr3_-_185461768 0.661 NM_033259
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr3_-_130761967 0.659 PLXND1
plexin D1
chr15_+_39573363 0.658 NM_002220
ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chr17_-_44026042 0.657 NM_002147
HOXB5
homeobox B5
chr19_+_1223475 0.656 CIRBP
cold inducible RNA binding protein
chr6_-_130578110 0.656 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr16_+_2747491 0.655


chr7_+_101715110 0.654 NM_020979
SH2B2
SH2B adaptor protein 2
chr16_+_66433882 0.652 THAP11
THAP domain containing 11
chr15_+_49421004 0.650 NM_181789
GLDN
gliomedin
chr19_+_43616167 0.650 NM_000540
NM_001042723
RYR1

ryanodine receptor 1 (skeletal)

chrX_-_62921937 0.646 NM_001173479
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr2_+_98070026 0.645 NM_144992
VWA3B
von Willebrand factor A domain containing 3B
chr9_-_138387926 0.644 NM_052813
NM_052814
CARD9

caspase recruitment domain family, member 9

chr1_-_46853380 0.644 NM_145279
MOBKL2C
MOB1, Mps One Binder kinase activator-like 2C (yeast)
chr7_+_90177082 0.644 CDK14
cyclin-dependent kinase 14
chr2_+_68445936 0.643 PLEK
pleckstrin
chr15_-_72513053 0.640 NM_001146030
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr5_+_140871107 0.639


chr1_+_26671488 0.638 NM_005517
HMGN2
high-mobility group nucleosomal binding domain 2
chr17_-_38081967 0.637 NM_024927
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr9_-_21375258 0.636 NM_000605
IFNA2
interferon, alpha 2
chr1_-_150862202 0.635 NM_178431
LCE3A
late cornified envelope 3A
chr5_+_31675181 0.635 PDZD2
PDZ domain containing 2
chr19_-_17217022 0.634 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr10_+_94439658 0.634 NM_002729
HHEX
hematopoietically expressed homeobox
chr7_+_100113664 0.633 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr11_-_117589283 0.632 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr6_-_31853027 0.630 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr1_-_219977424 0.630 NM_144728
DUSP10
dual specificity phosphatase 10
chr7_+_37926943 0.628 EPDR1
ependymin related protein 1 (zebrafish)
chr19_+_59777049 0.627 NM_001130917
NM_006866
LILRA2

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2

chr20_-_2769120 0.626 FAM113A
family with sequence similarity 113, member A
chr5_-_169657360 0.626 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_-_39630951 0.623 NM_001098833
NM_020218
ATXN7L3

ataxin 7-like 3

chr7_-_38356100 0.622 TRGV5
T cell receptor gamma variable 5
chr15_-_75259714 0.622 PEAK1
NKF3 kinase family member
chr11_-_67174684 0.622 NM_080658
ACY3
aspartoacylase (aminocyclase) 3
chr17_-_71352017 0.621 UNC13D
unc-13 homolog D (C. elegans)
chr7_+_50318801 0.619 IKZF1
IKAROS family zinc finger 1 (Ikaros)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.30 2.59e-10 GO:0030154 cell differentiation
1.28 1.54e-09 GO:0048869 cellular developmental process
1.42 1.92e-08 GO:0050793 regulation of developmental process
1.11 3.08e-08 GO:0065007 biological regulation
1.32 4.55e-08 GO:0007399 nervous system development
1.48 6.13e-08 GO:0045595 regulation of cell differentiation
1.18 6.28e-08 GO:0032502 developmental process
1.40 6.35e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.34 7.65e-08 GO:0051239 regulation of multicellular organismal process
1.19 8.47e-08 GO:0007275 multicellular organismal development
1.22 2.58e-07 GO:0048518 positive regulation of biological process
1.11 2.99e-07 GO:0050794 regulation of cellular process
1.21 3.34e-07 GO:0048731 system development
1.39 1.04e-06 GO:0022008 neurogenesis
1.19 1.05e-06 GO:0048856 anatomical structure development
1.45 1.68e-06 GO:0031327 negative regulation of cellular biosynthetic process
1.13 1.85e-06 GO:0032501 multicellular organismal process
1.42 1.92e-06 GO:2000026 regulation of multicellular organismal development
1.39 2.03e-06 GO:0048699 generation of neurons
1.44 2.70e-06 GO:0009890 negative regulation of biosynthetic process
1.50 2.86e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.50 2.92e-06 GO:0051253 negative regulation of RNA metabolic process
1.47 3.68e-06 GO:0010629 negative regulation of gene expression
1.10 3.69e-06 GO:0050789 regulation of biological process
1.46 4.12e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.46 4.60e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.21 5.43e-06 GO:0048522 positive regulation of cellular process
1.44 6.99e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.16 8.25e-06 GO:0023052 signaling
1.25 1.63e-05 GO:0007166 cell surface receptor linked signaling pathway
1.44 2.12e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41 4.51e-05 GO:0010628 positive regulation of gene expression
1.50 8.12e-05 GO:0032583 regulation of gene-specific transcription
1.37 1.80e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 1.84e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.39 2.33e-04 GO:0051254 positive regulation of RNA metabolic process
1.19 2.62e-04 GO:0048519 negative regulation of biological process
1.46 2.63e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.20 3.25e-04 GO:0048523 negative regulation of cellular process
1.40 3.92e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.37 6.00e-04 GO:0030182 neuron differentiation
1.15 6.75e-04 GO:0007165 signal transduction
1.24 1.36e-03 GO:0009653 anatomical structure morphogenesis
1.32 1.39e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.56 1.61e-03 GO:0030029 actin filament-based process
1.53 1.73e-03 GO:0060284 regulation of cell development
1.05 1.85e-03 GO:0009987 cellular process
1.32 1.85e-03 GO:0009891 positive regulation of biosynthetic process
1.49 1.88e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.47 2.06e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.44 2.66e-03 GO:0051094 positive regulation of developmental process
1.18 2.71e-03 GO:0051252 regulation of RNA metabolic process
1.16 3.09e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18 3.36e-03 GO:0006355 regulation of transcription, DNA-dependent
1.33 3.48e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.16 5.30e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.55 5.82e-03 GO:0045596 negative regulation of cell differentiation
1.29 6.26e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.18 6.42e-03 GO:0065008 regulation of biological quality
1.21 8.23e-03 GO:0023051 regulation of signaling
1.28 8.47e-03 GO:0048468 cell development
1.19 9.53e-03 GO:0048513 organ development
1.49 1.00e-02 GO:0051093 negative regulation of developmental process
1.16 1.05e-02 GO:0031326 regulation of cellular biosynthetic process
1.39 1.14e-02 GO:0001775 cell activation
1.27 1.16e-02 GO:0009892 negative regulation of metabolic process
1.13 1.34e-02 GO:0031323 regulation of cellular metabolic process
1.15 1.35e-02 GO:0009889 regulation of biosynthetic process
1.28 1.45e-02 GO:0031324 negative regulation of cellular metabolic process
1.54 1.67e-02 GO:0030036 actin cytoskeleton organization
1.62 1.70e-02 GO:0032582 negative regulation of gene-specific transcription
1.46 2.29e-02 GO:0045597 positive regulation of cell differentiation
1.15 2.39e-02 GO:0010468 regulation of gene expression
1.27 3.57e-02 GO:0006351 transcription, DNA-dependent
1.12 4.26e-02 GO:0080090 regulation of primary metabolic process
1.46 4.30e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.18 4.57e-02 GO:0048583 regulation of response to stimulus
1.49 4.71e-02 GO:0051960 regulation of nervous system development
1.15 4.72e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.15 4.96e-02 GO:0010556 regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 7.82e-06 GO:0044459 plasma membrane part
1.52 8.11e-06 GO:0043005 neuron projection
1.13 3.55e-05 GO:0071944 cell periphery
1.74 4.75e-05 GO:0030424 axon
1.13 7.91e-05 GO:0005886 plasma membrane
2.08 3.32e-04 GO:0033267 axon part
1.45 4.90e-04 GO:0045202 synapse
1.25 1.79e-02 GO:0042995 cell projection
1.80 2.14e-02 GO:0016585 chromatin remodeling complex
1.52 3.51e-02 GO:0030425 dendrite

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.37 1.70e-07 GO:0001071 nucleic acid binding transcription factor activity
1.37 1.70e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.40 7.87e-06 GO:0043565 sequence-specific DNA binding
1.31 2.40e-05 GO:0030528 transcription regulator activity
1.08 2.58e-04 GO:0005515 protein binding
1.34 1.05e-02 GO:0008092 cytoskeletal protein binding
1.58 1.15e-02 GO:0005244 voltage-gated ion channel activity
1.58 1.15e-02 GO:0022832 voltage-gated channel activity
1.42 2.33e-02 GO:0003779 actin binding