Motif ID: MAZ.p2

Z-value: 2.333


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297261950.721.8e-03Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_809879 2.744 NM_006651
CPLX1
complexin 1
chrX_+_138060 2.731 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr8_+_144706699 2.528 NM_001166237
GSDMD
gasdermin D
chr20_+_61841662 2.505 SLC2A4RG
SLC2A4 regulator
chr22_+_48927610 2.374 NM_001164106
MOV10L1
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr18_-_28606839 2.330 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr2_+_232281491 2.311 PTMA
prothymosin, alpha
chr2_+_42128521 2.160 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr2_-_25328452 2.147 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr20_-_34635091 2.094


chr2_+_220116986 2.084 NM_001005209
TMEM198
transmembrane protein 198
chr14_-_21064182 2.064 SALL2
sal-like 2 (Drosophila)
chr17_-_39652449 2.027 NM_001076684
UBTF
upstream binding transcription factor, RNA polymerase I
chr2_+_220117009 2.012 TMEM198
transmembrane protein 198
chr4_-_6253152 2.008 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr20_-_61755145 1.962 NM_015894
STMN3
stathmin-like 3
chr20_-_30534848 1.930 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr20_+_61841553 1.922 NM_020062
SLC2A4RG
SLC2A4 regulator
chr3_-_10522221 1.838 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr20_-_3097070 1.807 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr3_-_10522267 1.800 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr17_-_34014390 1.779 SRCIN1
SRC kinase signaling inhibitor 1
chr20_+_44083667 1.761 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr15_-_62854749 1.737 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr3_-_10522340 1.735 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr7_+_5289079 1.729 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr4_-_1156362 1.713 SPON2
spondin 2, extracellular matrix protein
chr2_-_74634569 1.709 NM_032603
LOXL3
lysyl oxidase-like 3
chr12_+_93066370 1.703 NM_005761
PLXNC1
plexin C1
chr7_-_158073121 1.698 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr14_+_31615922 1.694 ARHGAP5
Rho GTPase activating protein 5
chr12_+_56291484 1.684 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr17_-_34157962 1.676 NM_007144
PCGF2
polycomb group ring finger 2
chr4_-_1156533 1.659 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr4_-_1156378 1.654 SPON2
spondin 2, extracellular matrix protein
chr2_+_232281470 1.641 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr4_-_1156458 1.641 SPON2
spondin 2, extracellular matrix protein
chr10_-_135021502 1.634 NM_001098483
NM_198472
C10orf125

chromosome 10 open reading frame 125

chr9_-_139564656 1.632 NM_001098537
NM_152286
PNPLA7

patatin-like phospholipase domain containing 7

chrX_+_9392980 1.614 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr7_-_102044374 1.603 RASA4
RAS p21 protein activator 4
chr6_+_7052798 1.590 NM_001168344
RREB1
ras responsive element binding protein 1
chr16_-_265868 1.578 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr14_+_31615959 1.578 ARHGAP5
Rho GTPase activating protein 5
chr19_-_2672337 1.578 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr17_-_39652391 1.559 UBTF
upstream binding transcription factor, RNA polymerase I
chr13_-_113066202 1.525 GRTP1
growth hormone regulated TBC protein 1
chr20_-_60963390 1.523 NM_006602
TCFL5
transcription factor-like 5 (basic helix-loop-helix)
chr11_+_47236072 1.514 NM_001130101
NM_005693
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr1_-_27802688 1.511 NM_001029882
AHDC1
AT hook, DNA binding motif, containing 1
chr18_-_22383066 1.501 NM_001136205
KCTD1
potassium channel tetramerisation domain containing 1
chr17_+_45008473 1.498 NXPH3
neurexophilin 3
chr20_-_10602429 1.490 NM_000214
JAG1
jagged 1
chr13_-_113066366 1.476 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr6_+_7052985 1.466 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr19_+_1200882 1.418 MIDN
midnolin
chr10_-_103525646 1.415 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr2_-_174537354 1.411 SP3
Sp3 transcription factor
chr2_+_72998111 1.405 NM_004097
EMX1
empty spiracles homeobox 1
chr20_+_17498507 1.373 NM_001011546
NM_006870
DSTN

destrin (actin depolymerizing factor)

chr1_-_27802947 1.373 AHDC1
AT hook, DNA binding motif, containing 1
chr2_+_115635982 1.372 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr1_+_3679168 1.356 NM_001163724
LOC388588
hypothetical protein LOC388588
chr4_+_995395 1.351 FGFRL1
fibroblast growth factor receptor-like 1
chr16_-_2186465 1.349 NM_020764
CASKIN1
CASK interacting protein 1
chr14_+_20608179 1.345 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr9_+_139619957 1.341 ARRDC1
arrestin domain containing 1
chr20_+_34635362 1.327 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr7_-_102044419 1.326 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr20_-_30535045 1.318 C20orf112
chromosome 20 open reading frame 112
chr20_+_39199263 1.310 PLCG1
phospholipase C, gamma 1
chr20_+_60918836 1.309 NM_001853
COL9A3
collagen, type IX, alpha 3
chr16_+_51722285 1.303 CHD9
chromodomain helicase DNA binding protein 9
chr19_+_659766 1.301 NM_001040134
NM_002579
PALM

paralemmin

chr12_+_6290359 1.296 NM_001144856
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr6_-_86409701 1.287 NM_001159677
NM_006372
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr16_+_2503676 1.281 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr14_-_21074875 1.277 NM_005407
SALL2
sal-like 2 (Drosophila)
chr20_-_44370537 1.275 CDH22
cadherin 22, type 2
chr11_+_56984702 1.273 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr12_+_6290127 1.271 PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr19_-_1966628 1.269 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr20_+_62181878 1.249 NM_000913
NM_182647
OPRL1

opiate receptor-like 1

chr20_-_60375695 1.245 NM_005560
LAMA5
laminin, alpha 5
chr2_-_207738858 1.241 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr16_+_84202515 1.239 NM_001134473
KIAA0182
KIAA0182
chr14_+_104261578 1.231 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr11_-_66897584 1.231 NM_013246
CLCF1
cardiotrophin-like cytokine factor 1
chr19_-_55524445 1.222 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr6_-_86409415 1.216 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr17_-_33982580 1.212 SRCIN1
SRC kinase signaling inhibitor 1
chrX_+_118776572 1.208 NM_001105576
ANKRD58
ankyrin repeat domain 58
chr14_-_94855848 1.206 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr12_+_54700955 1.183 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr17_+_45008175 1.173 NM_007225
NXPH3
neurexophilin 3
chr19_+_40451842 1.169 USF2
upstream transcription factor 2, c-fos interacting
chr4_+_995609 1.166 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr20_+_1154763 1.165 NM_001136566
RAD21L1
RAD21-like 1 (S. pombe)
chr2_-_43306650 1.153 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr14_+_23907065 1.152 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr2_+_79593567 1.145 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr20_-_17610828 1.143 NM_001042576
NM_004587
RRBP1

ribosome binding protein 1 homolog 180kDa (dog)

chr14_-_26136799 1.122 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr12_-_53268538 1.119 NM_006741
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr22_+_43442987 1.115 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr16_-_960982 1.113 NM_022773
LMF1
lipase maturation factor 1
chr7_-_86942910 1.109 NM_000443
NM_018849
NM_018850
ABCB4


ATP-binding cassette, sub-family B (MDR/TAP), member 4


chr14_+_23508922 1.107 NM_001193636
NM_001193637
NM_001193635
DHRS4L2


DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 2


dehydrogenase/reductase (SDR family) member 4 like 1
chr9_+_139619875 1.095 NM_152285
ARRDC1
arrestin domain containing 1
chr16_+_19087035 1.093 NM_016524
SYT17
synaptotagmin XVII
chr2_-_26058941 1.081 NM_002254
KIF3C
kinesin family member 3C
chr6_+_7053183 1.074 RREB1
ras responsive element binding protein 1
chr1_-_149698516 1.071 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chr19_-_6453224 1.070 NM_006087
TUBB4
tubulin, beta 4
chr19_+_8180179 1.070 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr19_+_45728270 1.069 SPTBN4
spectrin, beta, non-erythrocytic 4
chr15_-_80125514 1.067 MEX3B
mex-3 homolog B (C. elegans)
chr17_-_35331435 1.065 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr9_-_139068269 1.063 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr1_-_36562341 1.059 NM_018166
FAM176B
family with sequence similarity 176, member B
chr22_+_27931685 1.056 NM_133455
EMID1
EMI domain containing 1
chr18_+_44319365 1.048 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr5_-_134397740 1.048 NM_002653
PITX1
paired-like homeodomain 1
chr20_+_48240705 1.046 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr16_-_11588525 1.045 LITAF
lipopolysaccharide-induced TNF factor
chr16_+_1979959 1.044 NM_004209
SYNGR3
synaptogyrin 3
chr6_+_33495824 1.044 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr7_-_97868101 1.042 BAIAP2L1
BAI1-associated protein 2-like 1
chr13_+_99431417 1.042


chr14_-_20562962 1.036 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr2_+_159021712 1.030 NM_001005476
NM_003628
PKP4

plakophilin 4

chr1_+_945331 1.030 NM_198576
AGRN
agrin
chr16_-_88295595 1.027 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr9_+_139619917 1.021 ARRDC1
arrestin domain containing 1
chr16_+_1323627 1.020 BAIAP3
BAI1-associated protein 3
chr16_-_30042083 1.014 NM_001040056
NM_001109891
NM_002746
MAPK3


mitogen-activated protein kinase 3


chr16_-_30042030 1.012 MAPK3
mitogen-activated protein kinase 3
chr20_-_62181588 1.012 NM_001039467
RGS19
regulator of G-protein signaling 19
chr19_+_40451807 1.010 USF2
upstream transcription factor 2, c-fos interacting
chr17_-_60483278 1.009


chr1_-_40903897 1.000 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr14_+_105024301 0.998 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr19_-_2653662 0.995 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr17_-_4792433 0.995 PFN1
profilin 1
chr11_+_17714070 0.990 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr14_+_105024576 0.988 CRIP1
cysteine-rich protein 1 (intestinal)
chr2_+_242322645 0.984 NM_152783
D2HGDH
D-2-hydroxyglutarate dehydrogenase
chr19_+_45728207 0.981 NM_025213
SPTBN4
spectrin, beta, non-erythrocytic 4
chr16_-_960796 0.981 LMF1
lipase maturation factor 1
chr19_-_8581559 0.975 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr20_-_10602139 0.971 JAG1
jagged 1
chr22_+_49386044 0.971 MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr8_+_22078589 0.970 NM_001199
NM_006129
BMP1

bone morphogenetic protein 1

chr22_+_49385966 0.970 NM_012324
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr16_+_620932 0.968 NM_053284
WFIKKN1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr2_-_26058831 0.966 KIF3C
kinesin family member 3C
chr2_-_10506033 0.965 ODC1
ornithine decarboxylase 1
chr1_+_225982862 0.965 LOC100130093
hypothetical LOC100130093
chr14_-_23090606 0.963 NM_033400
ZFHX2
zinc finger homeobox 2
chr12_-_49878216 0.958 NM_002702
POU6F1
POU class 6 homeobox 1
chr6_+_99389318 0.957 POU3F2
POU class 3 homeobox 2
chr19_+_1397268 0.956 APC2
adenomatosis polyposis coli 2
chr8_-_37876129 0.948 NM_001002814
NM_025151
RAB11FIP1

RAB11 family interacting protein 1 (class I)

chr16_+_25610847 0.943 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr9_+_139619977 0.942 ARRDC1
arrestin domain containing 1
chr19_-_59666705 0.941 NM_198988
LENG9
leukocyte receptor cluster (LRC) member 9
chr2_+_200031333 0.941


chr5_+_109052984 0.939


chr2_+_42649105 0.936 NM_020744
MTA3
metastasis associated 1 family, member 3
chr2_+_46779553 0.935 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr7_-_51351952 0.934 NM_015198
COBL
cordon-bleu homolog (mouse)
chr14_+_104337923 0.934 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr14_+_31616196 0.932 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr6_-_86409375 0.930 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr19_+_3310138 0.927 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr10_+_124897627 0.926 NM_005519
HMX2
H6 family homeobox 2
chr6_+_99389300 0.919 NM_005604
POU3F2
POU class 3 homeobox 2
chr14_-_76564374 0.919 IRF2BPL
interferon regulatory factor 2 binding protein-like
chr12_+_56230047 0.916 KIF5A
kinesin family member 5A
chr19_-_18409788 0.915 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr4_+_996251 0.914 NM_021923
FGFRL1
fibroblast growth factor receptor-like 1
chr20_-_17610704 0.913 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr17_-_36938025 0.912 KRT19
keratin 19
chr21_-_44485127 0.910 NM_015259
ICOSLG
inducible T-cell co-stimulator ligand
chr22_-_40652724 0.904 NM_052945
TNFRSF13C
tumor necrosis factor receptor superfamily, member 13C
chr14_-_22891865 0.902 NM_016609
SLC22A17
solute carrier family 22, member 17
chr20_-_17986520 0.901 NM_021220
OVOL2
ovo-like 2 (Drosophila)
chr19_-_1188840 0.899 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr13_+_112671497 0.896 MCF2L
MCF.2 cell line derived transforming sequence-like
chr17_-_73867748 0.895 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr20_-_49592444 0.891 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr19_+_1199548 0.891 NM_177401
MIDN
midnolin
chr16_-_11588257 0.891 NM_001136472
NM_001136473
LITAF

lipopolysaccharide-induced TNF factor

chr17_+_26839143 0.886 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr20_+_61842174 0.885 SLC2A4RG
SLC2A4 regulator
chr17_+_72880831 0.883 NM_001113493
SEPT9
septin 9
chr2_-_80384997 0.877 NM_178839
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr19_-_48835783 0.875 NM_145296
CADM4
cell adhesion molecule 4
chr5_+_139155569 0.874 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr17_-_39632845 0.872 ATXN7L3
ataxin 7-like 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.07 1.11e-22 GO:0009987 cellular process
1.10 9.58e-16 GO:0050794 regulation of cellular process
1.09 7.59e-15 GO:0065007 biological regulation
1.10 9.46e-15 GO:0050789 regulation of biological process
1.20 5.00e-12 GO:0048523 negative regulation of cellular process
1.10 1.03e-11 GO:0044237 cellular metabolic process
1.18 2.81e-11 GO:0048519 negative regulation of biological process
1.14 4.03e-11 GO:0080090 regulation of primary metabolic process
1.13 5.00e-11 GO:0044260 cellular macromolecule metabolic process
1.22 1.04e-10 GO:0023051 regulation of signaling
1.14 1.35e-10 GO:0031323 regulation of cellular metabolic process
1.14 4.86e-10 GO:0016043 cellular component organization
1.14 5.29e-10 GO:0060255 regulation of macromolecule metabolic process
1.13 7.98e-10 GO:0019222 regulation of metabolic process
1.08 2.13e-09 GO:0008152 metabolic process
1.19 2.32e-09 GO:0030154 cell differentiation
1.23 3.02e-09 GO:0009966 regulation of signal transduction
1.18 3.52e-09 GO:0048869 cellular developmental process
1.13 5.58e-09 GO:0071840 cellular component organization or biogenesis
1.09 1.13e-08 GO:0044238 primary metabolic process
1.16 1.24e-08 GO:0071842 cellular component organization at cellular level
1.15 2.48e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.27 3.46e-08 GO:0010605 negative regulation of macromolecule metabolic process
1.15 5.54e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 1.31e-07 GO:0010468 regulation of gene expression
1.14 1.32e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.20 1.40e-07 GO:0007399 nervous system development
1.10 1.81e-07 GO:0043170 macromolecule metabolic process
1.25 1.82e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.25 2.74e-07 GO:0009892 negative regulation of metabolic process
1.15 2.86e-07 GO:0048522 positive regulation of cellular process
1.14 3.42e-07 GO:0048518 positive regulation of biological process
1.26 4.87e-07 GO:0022008 neurogenesis
1.11 6.96e-07 GO:0032502 developmental process
1.15 8.32e-07 GO:0051252 regulation of RNA metabolic process
1.25 9.04e-07 GO:0048468 cell development
1.25 1.08e-06 GO:0031324 negative regulation of cellular metabolic process
1.14 1.78e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19 1.93e-06 GO:0009653 anatomical structure morphogenesis
1.30 2.34e-06 GO:0010629 negative regulation of gene expression
1.25 3.21e-06 GO:0006351 transcription, DNA-dependent
1.29 3.27e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.25 3.69e-06 GO:0048699 generation of neurons
1.30 3.73e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.14 3.80e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.27 7.15e-06 GO:0030182 neuron differentiation
1.27 7.24e-06 GO:0009890 negative regulation of biosynthetic process
1.31 1.16e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.12 1.58e-05 GO:0048856 anatomical structure development
1.14 1.59e-05 GO:0044249 cellular biosynthetic process
1.30 1.74e-05 GO:0048666 neuron development
1.13 2.16e-05 GO:0009058 biosynthetic process
1.13 2.27e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.27 2.72e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.27 3.26e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.30 3.34e-05 GO:0051253 negative regulation of RNA metabolic process
1.11 3.58e-05 GO:0007275 multicellular organismal development
1.14 3.77e-05 GO:0090304 nucleic acid metabolic process
1.28 4.13e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 5.08e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.14 5.33e-05 GO:0006355 regulation of transcription, DNA-dependent
1.12 5.92e-05 GO:0048731 system development
1.30 6.40e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.16 6.44e-05 GO:0034645 cellular macromolecule biosynthetic process
1.11 7.44e-05 GO:0034641 cellular nitrogen compound metabolic process
1.11 8.30e-05 GO:0006807 nitrogen compound metabolic process
1.20 8.51e-05 GO:0051246 regulation of protein metabolic process
1.16 9.64e-05 GO:0009059 macromolecule biosynthetic process
1.20 1.06e-04 GO:0010646 regulation of cell communication
1.26 1.18e-04 GO:0030030 cell projection organization
1.15 1.49e-04 GO:0006464 protein modification process
1.30 1.56e-04 GO:0031175 neuron projection development
1.14 1.87e-04 GO:0043412 macromolecule modification
1.12 2.07e-04 GO:0031326 regulation of cellular biosynthetic process
1.12 2.17e-04 GO:0009889 regulation of biosynthetic process
1.15 2.82e-04 GO:0016070 RNA metabolic process
1.20 3.41e-04 GO:0032268 regulation of cellular protein metabolic process
1.15 3.45e-04 GO:0010467 gene expression
1.11 6.92e-04 GO:0051234 establishment of localization
1.32 8.65e-04 GO:0043009 chordate embryonic development
1.39 8.81e-04 GO:0030036 actin cytoskeleton organization
1.11 9.90e-04 GO:0006810 transport
1.09 1.30e-03 GO:0023052 signaling
1.24 1.32e-03 GO:0045595 regulation of cell differentiation
1.31 1.52e-03 GO:0009792 embryo development ending in birth or egg hatching
1.12 1.73e-03 GO:0044267 cellular protein metabolic process
1.30 1.90e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.19 1.96e-03 GO:0032774 RNA biosynthetic process
1.19 2.08e-03 GO:0042981 regulation of apoptosis
1.30 2.57e-03 GO:0007264 small GTPase mediated signal transduction
1.18 2.68e-03 GO:0043067 regulation of programmed cell death
1.27 3.25e-03 GO:0007010 cytoskeleton organization
1.09 3.36e-03 GO:0051179 localization
1.28 4.41e-03 GO:0048812 neuron projection morphogenesis
1.30 4.66e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.22 4.98e-03 GO:0006915 apoptosis
1.19 5.10e-03 GO:0050793 regulation of developmental process
1.18 5.23e-03 GO:0010941 regulation of cell death
1.15 5.63e-03 GO:0035556 intracellular signal transduction
1.14 5.73e-03 GO:0006996 organelle organization
1.28 5.92e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.28 6.44e-03 GO:0007409 axonogenesis
1.21 6.68e-03 GO:0012501 programmed cell death
1.19 7.42e-03 GO:0016265 death
1.22 7.52e-03 GO:0009790 embryo development
1.33 9.68e-03 GO:0030029 actin filament-based process
1.13 9.89e-03 GO:0048583 regulation of response to stimulus
1.29 1.06e-02 GO:0016568 chromatin modification
1.19 1.11e-02 GO:0008219 cell death
1.27 1.58e-02 GO:0032583 regulation of gene-specific transcription
1.25 1.60e-02 GO:0048858 cell projection morphogenesis
1.22 1.63e-02 GO:0032989 cellular component morphogenesis
1.25 1.65e-02 GO:0000904 cell morphogenesis involved in differentiation
1.19 1.89e-02 GO:0031399 regulation of protein modification process
1.15 2.07e-02 GO:0051641 cellular localization
1.31 2.18e-02 GO:0060284 regulation of cell development
1.22 2.19e-02 GO:0000902 cell morphogenesis
1.34 2.38e-02 GO:0051248 negative regulation of protein metabolic process
1.24 2.41e-02 GO:0032990 cell part morphogenesis
1.26 2.43e-02 GO:0010648 negative regulation of cell communication
1.30 2.72e-02 GO:0007411 axon guidance
1.49 2.78e-02 GO:0007265 Ras protein signal transduction
1.26 3.10e-02 GO:0023057 negative regulation of signaling
1.36 3.10e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.18 3.53e-02 GO:0051128 regulation of cellular component organization
1.16 4.21e-02 GO:0007049 cell cycle
1.25 4.22e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.26 4.89e-02 GO:0009968 negative regulation of signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 1.18e-36 GO:0005622 intracellular
1.09 8.66e-35 GO:0044424 intracellular part
1.11 7.97e-28 GO:0005737 cytoplasm
1.09 6.68e-22 GO:0043227 membrane-bounded organelle
1.09 1.81e-21 GO:0043231 intracellular membrane-bounded organelle
1.08 1.64e-20 GO:0043226 organelle
1.08 2.37e-20 GO:0043229 intracellular organelle
1.12 2.49e-16 GO:0005634 nucleus
1.11 7.86e-14 GO:0044444 cytoplasmic part
1.18 1.40e-10 GO:0005829 cytosol
1.17 4.33e-09 GO:0044428 nuclear part
1.18 1.20e-08 GO:0031981 nuclear lumen
1.16 1.72e-08 GO:0043233 organelle lumen
1.16 2.16e-08 GO:0070013 intracellular organelle lumen
1.15 3.26e-08 GO:0031974 membrane-enclosed lumen
1.08 8.85e-07 GO:0044446 intracellular organelle part
1.08 8.87e-07 GO:0044422 organelle part
1.02 1.93e-06 GO:0044464 cell part
1.02 2.16e-06 GO:0005623 cell
1.28 5.26e-06 GO:0030054 cell junction
1.18 5.73e-06 GO:0005654 nucleoplasm
1.23 9.54e-05 GO:0016023 cytoplasmic membrane-bounded vesicle
1.22 1.72e-04 GO:0031410 cytoplasmic vesicle
1.22 2.33e-04 GO:0031988 membrane-bounded vesicle
1.21 2.92e-04 GO:0031982 vesicle
1.45 3.15e-04 GO:0070161 anchoring junction
1.14 4.61e-04 GO:0012505 endomembrane system
1.29 5.45e-04 GO:0045202 synapse
1.10 8.06e-04 GO:0043234 protein complex
1.18 8.81e-04 GO:0005794 Golgi apparatus
1.53 1.29e-03 GO:0030055 cell-substrate junction
1.36 1.30e-03 GO:0016323 basolateral plasma membrane
1.55 1.42e-03 GO:0005925 focal adhesion
1.27 1.96e-03 GO:0043005 neuron projection
1.44 2.54e-03 GO:0005912 adherens junction
1.52 2.84e-03 GO:0005924 cell-substrate adherens junction
1.54 6.48e-03 GO:0042470 melanosome
1.54 6.48e-03 GO:0048770 pigment granule
1.18 1.62e-02 GO:0044451 nucleoplasm part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 2.40e-28 GO:0005515 protein binding
1.06 6.85e-22 GO:0005488 binding
1.29 1.61e-08 GO:0019899 enzyme binding
1.24 1.25e-07 GO:0001071 nucleic acid binding transcription factor activity
1.24 1.25e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.23 3.84e-07 GO:0030528 transcription regulator activity
1.28 4.00e-07 GO:0043565 sequence-specific DNA binding
1.28 2.23e-04 GO:0030695 GTPase regulator activity
1.29 3.24e-04 GO:0019904 protein domain specific binding
1.12 3.72e-04 GO:0003677 DNA binding
1.27 5.64e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.09 1.12e-03 GO:0003676 nucleic acid binding
1.33 1.13e-03 GO:0016564 transcription repressor activity
1.11 1.26e-03 GO:0000166 nucleotide binding
1.08 1.28e-03 GO:0046872 metal ion binding
1.08 1.90e-03 GO:0043167 ion binding
1.08 1.91e-03 GO:0043169 cation binding
1.41 1.95e-03 GO:0003682 chromatin binding
1.29 2.06e-03 GO:0000988 protein binding transcription factor activity
1.29 2.06e-03 GO:0000989 transcription factor binding transcription factor activity
1.21 2.49e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.28 2.68e-03 GO:0003712 transcription cofactor activity
1.32 2.77e-03 GO:0005083 small GTPase regulator activity
1.18 3.29e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.34 5.12e-03 GO:0005096 GTPase activator activity
1.30 5.96e-03 GO:0016563 transcription activator activity
1.19 6.13e-03 GO:0016301 kinase activity
1.22 1.46e-02 GO:0008092 cytoskeletal protein binding
1.18 1.96e-02 GO:0042802 identical protein binding
1.39 2.58e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.11 3.78e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.10 4.15e-02 GO:0008270 zinc ion binding