Motif ID: POU2F1..3.p2

Z-value: 2.819


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F1chr1_+_1655650060.901.8e-06Click!
POU2F2chr19_-_473283990.332.1e-01Click!
POU2F3chr11_+_1196161120.097.4e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_153098811 10.201 NM_170782
 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_+_50318801 9.707 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr1_+_165565006 8.511 POU2F1
POU class 2 homeobox 1
chr1_+_165564904 8.253 NM_001198783
 POU2F1
POU class 2 homeobox 1
chr1_+_154386358 6.437 NM_001193301
 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_+_23754997 5.916 PRKCB
protein kinase C, beta
chr3_+_99733432 5.751 NM_005290
 GPR15
G protein-coupled receptor 15
chr22_+_20715340 5.532


chr16_+_23754860 5.514 PRKCB
protein kinase C, beta
chr1_+_202000906 5.039 NM_001136190
NM_017773
 LAX1

lymphocyte transmembrane adaptor 1

chr16_+_23754822 4.973 PRKCB
protein kinase C, beta
chr4_-_186970366 4.958 NM_003603
NM_001145670
 SORBS2

sorbin and SH3 domain containing 2

chr5_-_88155360 4.922 NM_001193348
NM_001193349
 MEF2C

myocyte enhancer factor 2C

chr16_+_23754772 4.813 NM_002738
NM_212535
 PRKCB

protein kinase C, beta

chr4_-_40212670 4.804 NM_019027
 RBM47
RNA binding motif protein 47
chr19_-_18369407 4.639 NM_145256
 LRRC25
leucine rich repeat containing 25
chr12_+_91620749 4.599 NM_001037671
NM_001178097
 C12orf74

chromosome 12 open reading frame 74

chr17_-_59363352 4.564 NM_000626
NM_001039933
NM_021602
 CD79B


CD79b molecule, immunoglobulin-associated beta


chr5_-_176868483 4.563 DOK3
docking protein 3
chr10_-_98021144 4.353 NM_001114094
NM_013314
 BLNK

B-cell linker


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
6.90 2.12e-02 GO:0050909 sensory perception of taste
6.38 4.03e-06 GO:0006334 nucleosome assembly
6.12 2.51e-06 GO:0034728 nucleosome organization
6.06 8.88e-06 GO:0031497 chromatin assembly
5.91 1.51e-06 GO:0071824 protein-DNA complex subunit organization
5.90 4.59e-06 GO:0065004 protein-DNA complex assembly
5.15 5.73e-06 GO:0006333 chromatin assembly or disassembly
4.64 4.20e-04 GO:0006323 DNA packaging
4.41 2.16e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
4.24 3.21e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
4.23 6.77e-04 GO:0071103 DNA conformation change
2.66 9.07e-04 GO:0006325 chromatin organization
2.59 1.64e-06 GO:0006955 immune response
2.20 8.87e-04 GO:0006952 defense response
2.18 2.90e-02 GO:0051276 chromosome organization
2.08 2.28e-05 GO:0002376 immune system process
1.30 3.71e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
8.38 1.54e-07 GO:0000786 nucleosome
5.36 6.33e-05 GO:0032993 protein-DNA complex
3.66 1.65e-05 GO:0000785 chromatin

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
9.28 2.14e-05 GO:0003823 antigen binding
1.95 1.50e-03 GO:0001071 nucleic acid binding transcription factor activity
1.95 1.50e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 7.94e-03 GO:0004871 signal transducer activity
1.55 7.94e-03 GO:0060089 molecular transducer activity
1.53 4.39e-03 GO:0003677 DNA binding