Motif ID: POU5F1.p2

Z-value: 2.720


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_31246159-0.775.4e-04Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_76667045 10.156 NM_006682
FGL2
fibrinogen-like 2
chr15_-_40537002 7.282 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr4_-_153523113 6.578 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr3_-_64186151 6.484 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr10_-_98021144 5.877 NM_001114094
NM_013314
BLNK

B-cell linker

chr13_-_101852028 5.432 NM_175929
FGF14
fibroblast growth factor 14
chr22_-_44828636 4.489 NM_018280
C22orf26
chromosome 22 open reading frame 26
chr1_-_153098811 4.127 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr5_-_124108672 4.120 NM_020747
ZNF608
zinc finger protein 608
chr3_-_129023850 4.024 NM_007283
MGLL
monoglyceride lipase
chr4_-_110443247 4.011 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr14_-_93512818 3.922 ASB2
ankyrin repeat and SOCS box containing 2
chr7_+_18501876 3.717 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr7_-_41709191 3.681 NM_002192
INHBA
inhibin, beta A
chr6_-_26151863 3.593 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr7_+_113513828 3.568 FOXP2
forkhead box P2
chr1_-_215329569 3.510 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chrX_-_62891066 3.504 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr7_+_113513726 3.502 FOXP2
forkhead box P2
chr6_+_26291936 3.454 NM_003523
HIST1H2BE
histone cluster 1, H2be
chr5_-_36337756 3.444 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr4_+_81325447 3.371 NM_020226
PRDM8
PR domain containing 8
chr20_+_19863716 3.353 RIN2
Ras and Rab interactor 2
chr2_+_170742900 3.229 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr14_-_93512647 3.220 ASB2
ankyrin repeat and SOCS box containing 2
chr3_+_179736917 3.175 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr15_-_86600658 3.152 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr5_-_111119846 3.101 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr1_+_161305558 3.095 NM_001113381
RGS4
regulator of G-protein signaling 4
chr3_+_174598937 3.088 NM_014932
NLGN1
neuroligin 1
chrX_-_33267646 3.072 NM_000109
DMD
dystrophin
chr19_-_1083109 3.068 NM_001100122
SBNO2
strawberry notch homolog 2 (Drosophila)
chr1_+_242281175 3.008 NM_205768
ZNF238
zinc finger protein 238
chr15_-_78050515 2.958 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr6_+_131613196 2.911 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr18_+_40514772 2.890 NM_015559
SETBP1
SET binding protein 1
chr1_+_242281199 2.877 ZNF238
zinc finger protein 238
chr1_-_197173159 2.849 LOC100131234
familial acute myelogenous leukemia related factor
chr10_+_11246934 2.848 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr12_-_16649211 2.790 LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_100957883 2.778 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr12_+_14409875 2.755 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chrX_-_77801480 2.707 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr1_-_205012348 2.687 NM_000572
IL10
interleukin 10
chr2_-_55090759 2.653 NM_007008
RTN4
reticulon 4
chr3_+_135996990 2.622 EPHB1
EPH receptor B1
chr2_+_68815416 2.621 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr9_-_116920232 2.594 NM_002160
TNC
tenascin C
chr6_-_170442090 2.587


chr1_-_42156957 2.587 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr1_+_161305188 2.583 NM_005613
RGS4
regulator of G-protein signaling 4
chr3_+_135996734 2.576 NM_004441
EPHB1
EPH receptor B1
chr17_-_45427565 2.565 NM_005220
DLX3
distal-less homeobox 3
chr7_+_128795280 2.493 AHCYL2
adenosylhomocysteinase-like 2
chr4_+_77829634 2.485 SHROOM3
shroom family member 3
chr5_-_66528330 2.481 NM_005582
CD180
CD180 molecule
chr1_-_108308997 2.470 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr14_+_78815406 2.451 NM_001105250
NM_138970
NRXN3

neurexin 3

chr4_+_77829743 2.415 SHROOM3
shroom family member 3
chr7_+_128795178 2.389 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr9_-_16717887 2.372 BNC2
basonuclin 2
chr4_+_134289893 2.346 NM_020815
NM_032961
PCDH10

protocadherin 10

chr16_+_10878539 2.339 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr13_+_110637173 2.333 NM_001113513
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr10_-_116276651 2.329 NM_006720
ABLIM1
actin binding LIM protein 1
chr1_+_208008517 2.319 TRAF3IP3
TRAF3 interacting protein 3
chr17_-_44047299 2.317 NM_024016
HOXB8
homeobox B8
chr11_-_26700121 2.310 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr17_-_39094787 2.285 NM_001040002
MEOX1
mesenchyme homeobox 1
chr1_+_176577228 2.265 NM_004841
RASAL2
RAS protein activator like 2
chr12_-_101115677 2.247 NM_002674
PMCH
pro-melanin-concentrating hormone
chr6_+_21701942 2.216 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr6_-_130224108 2.201 NM_001010876
C6orf191
chromosome 6 open reading frame 191
chr11_+_128068982 2.167 NM_002017
FLI1
Friend leukemia virus integration 1
chr1_+_152567843 2.152 ATP8B2
ATPase, class I, type 8B, member 2
chr5_-_54317102 2.150 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chrX_-_138742050 2.149 NM_001010986
NM_173694
ATP11C

ATPase, class VI, type 11C

chr17_+_64922420 2.148 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr19_-_43800374 2.132 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr2_+_237143118 2.130 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr2_+_108751033 2.107 RANBP2
RAN binding protein 2
chr5_+_140871107 2.084


chr4_-_47534815 2.062 NM_006587
CORIN
corin, serine peptidase
chr15_+_55298908 2.057 NM_207040
TCF12
transcription factor 12
chr8_-_122722674 2.052 NM_005328
HAS2
hyaluronan synthase 2
chr1_-_42157077 2.044 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr4_-_153493133 2.035 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr5_+_152850276 2.033 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr6_+_30799130 2.031 TUBB
tubulin, beta
chr7_-_27149750 2.024 NM_019102
HOXA5
homeobox A5
chr6_+_106653429 2.007 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr1_-_181889070 1.998 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr7_-_129868059 1.997 NM_018718
TSGA14
testis specific, 14
chr2_+_210152399 1.994 MAP2
microtubule-associated protein 2
chr12_+_52713098 1.991 NM_018953
HOXC5
homeobox C5
chr1_+_15145001 1.987 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr1_+_84382529 1.987 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_+_70567634 1.981 SULF1
sulfatase 1
chr3_+_29297806 1.972 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chrX_-_77469635 1.967 NM_006639
CYSLTR1
cysteinyl leukotriene receptor 1
chr1_-_226712140 1.961 NM_033445
HIST3H2A
histone cluster 3, H2a
chr3_-_58175437 1.944 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr1_+_84382562 1.943 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_23768242 1.941 NM_003155
STC1
stanniocalcin 1
chr6_-_32892705 1.927 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr2_+_88966170 1.920


chr1_+_145479805 1.917 NM_004326
BCL9
B-cell CLL/lymphoma 9
chr4_-_164754106 1.909 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr5_-_146237826 1.896 PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr8_-_93181091 1.895 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_17599438 1.889 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr1_+_190811479 1.883 NM_002922
RGS1
regulator of G-protein signaling 1
chr1_+_107485071 1.861 NTNG1
netrin G1
chr7_+_45033757 1.859 NM_001029835
CCM2
cerebral cavernous malformation 2
chr1_+_84539876 1.858 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr7_-_83662152 1.858 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_+_10779191 1.854 NM_001039362
NM_144583
ATP6V1C2

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2

chr8_-_108579270 1.851 NM_001146
ANGPT1
angiopoietin 1
chr7_+_28418668 1.847 NM_182898
CREB5
cAMP responsive element binding protein 5
chr5_-_88155360 1.847 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr3_+_142587973 1.844


chr3_+_182912405 1.837 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr1_+_213245507 1.835 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr11_+_5610060 1.828 NM_130390
TRIM34
tripartite motif containing 34
chr1_+_66570683 1.828 PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_+_140870881 1.827


chr7_+_129720209 1.822 NM_001163446
NM_016352
CPA4

carboxypeptidase A4

chr1_+_65503011 1.819 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chrX_-_43717864 1.812 NM_000266
NDP
Norrie disease (pseudoglioma)
chr2_+_189547358 1.805 COL3A1
collagen, type III, alpha 1
chr10_+_91488704 1.801 KIF20B
kinesin family member 20B
chr5_+_36644187 1.787 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_+_70567581 1.775 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr9_+_131123115 1.768 NM_001012715
C9orf106
chromosome 9 open reading frame 106
chr4_+_154293719 1.758 NM_001130067
TRIM2
tripartite motif containing 2
chr7_-_104696678 1.756 NM_182691
SRPK2
SRSF protein kinase 2
chr2_+_189547377 1.752 COL3A1
collagen, type III, alpha 1
chrX_-_10548458 1.739 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr8_+_123863075 1.737 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr22_-_26527469 1.736 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr10_-_64248932 1.731 NM_001136178
EGR2
early growth response 2
chr7_+_113513600 1.720 FOXP2
forkhead box P2
chr11_+_128069203 1.711 FLI1
Friend leukemia virus integration 1
chr16_+_81218142 1.711 CDH13
cadherin 13, H-cadherin (heart)
chr1_+_226712430 1.710 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr1_+_168898898 1.701 PRRX1
paired related homeobox 1
chr11_+_46339691 1.698 NM_001105540
DGKZ
diacylglycerol kinase, zeta
chr11_+_128069183 1.666 FLI1
Friend leukemia virus integration 1
chr12_-_16650697 1.662 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_48239865 1.659 NM_004345
CAMP
cathelicidin antimicrobial peptide
chr3_+_42107711 1.659 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chr9_+_112470871 1.652 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr11_-_34336102 1.648 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr17_-_8756524 1.647 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr8_+_123863169 1.639 ZHX2
zinc fingers and homeoboxes 2
chr1_+_84382575 1.638 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_5750229 1.630 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr1_+_66570363 1.628 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr8_+_86287161 1.628 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr12_+_111829121 1.625 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr14_+_64077171 1.623 HSPA2
heat shock 70kDa protein 2
chr11_+_128069165 1.622 FLI1
Friend leukemia virus integration 1
chr2_-_191580567 1.619 STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_+_17861266 1.616 NM_001105569
MSGN1
mesogenin 1
chr7_-_50103335 1.614 NM_001159878
NM_007009
ZPBP

zona pellucida binding protein

chr4_+_154397975 1.614 TRIM2
tripartite motif containing 2
chr14_-_106241445 1.614 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr12_-_90100679 1.607 DCN
decorin
chr2_+_210152609 1.597 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr6_-_134540666 1.586 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr18_+_54013575 1.586 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr9_+_124836666 1.580 NM_005294
GPR21
G protein-coupled receptor 21
chr1_+_81544432 1.573 LPHN2
latrophilin 2
chr10_+_91051685 1.573 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr6_+_170441715 1.568 FAM120B
family with sequence similarity 120B
chr4_+_124540114 1.555 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr8_+_123863224 1.555 ZHX2
zinc fingers and homeoboxes 2
chr8_+_67945537 1.531 NM_001136161
NM_173518
C8orf45

chromosome 8 open reading frame 45

chr6_-_42527760 1.529 NM_033502
TRERF1
transcriptional regulating factor 1
chr3_+_182912769 1.529 SOX2
SRY (sex determining region Y)-box 2
chr9_+_18464138 1.525 ADAMTSL1
ADAMTS-like 1
chr8_+_11388918 1.521 NM_001715
BLK
B lymphoid tyrosine kinase
chrX_-_106846684 1.513 TSC22D3
TSC22 domain family, member 3
chr10_-_116276560 1.513 ABLIM1
actin binding LIM protein 1
chr6_-_32665409 1.513 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr13_-_85271329 1.504 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr1_-_171442937 1.492 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr16_+_81218074 1.491 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr13_+_110653407 1.488 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr6_-_152999678 1.478 NM_033071
SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_+_49997489 1.476 NM_001178055
PARP8
poly (ADP-ribose) polymerase family, member 8
chr1_-_147665783 1.475 HIST2H2BF
histone cluster 2, H2bf
chr13_-_27572646 1.475 NM_004119
FLT3
fms-related tyrosine kinase 3
chr3_-_87122958 1.468 VGLL3
vestigial like 3 (Drosophila)
chr12_-_90100733 1.466 NM_001920
DCN
decorin
chr6_-_170441493 1.465 NM_005618
DLL1
delta-like 1 (Drosophila)
chr15_-_70399551 1.464 NM_052840
CELF6
CUGBP, Elav-like family member 6
chr12_-_90100710 1.463 DCN
decorin
chr15_-_70399523 1.447 CELF6
CUGBP, Elav-like family member 6
chr9_+_115382990 1.436 RGS3
regulator of G-protein signaling 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.27 1.35e-14 GO:0050794 regulation of cellular process
1.50 8.21e-14 GO:0048731 system development
1.23 3.36e-13 GO:0065007 biological regulation
1.24 5.46e-13 GO:0050789 regulation of biological process
1.42 4.52e-12 GO:0007275 multicellular organismal development
1.70 6.99e-12 GO:0007399 nervous system development
1.43 1.19e-11 GO:0048856 anatomical structure development
1.38 4.91e-11 GO:0032502 developmental process
1.29 3.68e-10 GO:0032501 multicellular organismal process
1.48 4.01e-09 GO:0051252 regulation of RNA metabolic process
1.49 5.13e-09 GO:0006355 regulation of transcription, DNA-dependent
1.50 1.10e-08 GO:0030154 cell differentiation
1.51 2.26e-08 GO:0048513 organ development
1.78 2.36e-08 GO:0022008 neurogenesis
1.36 2.61e-08 GO:0060255 regulation of macromolecule metabolic process
1.48 2.95e-08 GO:0048869 cellular developmental process
1.44 3.63e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.34 4.36e-08 GO:0080090 regulation of primary metabolic process
1.42 5.49e-08 GO:0010468 regulation of gene expression
1.57 7.59e-08 GO:0009653 anatomical structure morphogenesis
1.77 2.14e-07 GO:0048699 generation of neurons
1.34 2.22e-07 GO:0007165 signal transduction
1.32 2.45e-07 GO:0023052 signaling
1.41 2.93e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.21 1.16e-06 GO:0050896 response to stimulus
1.31 1.53e-06 GO:0031323 regulation of cellular metabolic process
1.37 2.07e-06 GO:0031326 regulation of cellular biosynthetic process
1.81 2.74e-06 GO:0030182 neuron differentiation
1.37 3.06e-06 GO:0009889 regulation of biosynthetic process
1.36 3.68e-06 GO:0048518 positive regulation of biological process
1.36 4.89e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.70 4.99e-06 GO:0040011 locomotion
1.27 6.82e-06 GO:0051716 cellular response to stimulus
1.79 9.45e-06 GO:0010628 positive regulation of gene expression
1.35 1.05e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.64 1.21e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.39 3.98e-05 GO:0048523 negative regulation of cellular process
1.26 4.74e-05 GO:0019222 regulation of metabolic process
1.43 5.37e-05 GO:0007166 cell surface receptor linked signaling pathway
1.82 5.42e-05 GO:0048666 neuron development
1.35 7.44e-05 GO:0048522 positive regulation of cellular process
1.76 7.62e-05 GO:0030030 cell projection organization
1.77 8.25e-05 GO:0045893 positive regulation of transcription, DNA-dependent
2.02 8.50e-05 GO:0048598 embryonic morphogenesis
1.69 1.00e-04 GO:2000026 regulation of multicellular organismal development
1.87 1.02e-04 GO:0031175 neuron projection development
1.33 1.20e-04 GO:0071842 cellular component organization at cellular level
2.09 1.36e-04 GO:0060284 regulation of cell development
1.91 1.50e-04 GO:0048812 neuron projection morphogenesis
1.91 1.60e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.71 1.60e-04 GO:0009790 embryo development
1.58 1.65e-04 GO:0009605 response to external stimulus
1.93 1.80e-04 GO:0007409 axonogenesis
1.10 1.95e-04 GO:0009987 cellular process
2.55 2.30e-04 GO:0009952 anterior/posterior pattern formation
2.24 2.87e-04 GO:0003002 regionalization
1.69 3.99e-04 GO:0045595 regulation of cell differentiation
1.58 4.02e-04 GO:0048468 cell development
1.57 7.31e-04 GO:0050793 regulation of developmental process
1.79 8.02e-04 GO:0007417 central nervous system development
1.64 8.39e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.55 8.56e-04 GO:0042127 regulation of cell proliferation
1.79 1.04e-03 GO:0048858 cell projection morphogenesis
1.33 1.16e-03 GO:0048519 negative regulation of biological process
1.30 1.24e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.67 1.24e-03 GO:0051254 positive regulation of RNA metabolic process
1.78 1.47e-03 GO:0000904 cell morphogenesis involved in differentiation
1.77 1.48e-03 GO:0032990 cell part morphogenesis
1.83 1.59e-03 GO:0032583 regulation of gene-specific transcription
1.95 1.76e-03 GO:0007389 pattern specification process
1.79 1.87e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.25 2.37e-03 GO:0016043 cellular component organization
1.69 2.60e-03 GO:0000902 cell morphogenesis
1.32 2.95e-03 GO:0042221 response to chemical stimulus
1.97 3.53e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.66 3.95e-03 GO:0032989 cellular component morphogenesis
1.66 5.71e-03 GO:0009887 organ morphogenesis
2.95 7.38e-03 GO:0048706 embryonic skeletal system development
1.70 8.02e-03 GO:0008284 positive regulation of cell proliferation
1.47 8.23e-03 GO:0010646 regulation of cell communication
1.49 8.63e-03 GO:0007154 cell communication
1.70 1.03e-02 GO:0006935 chemotaxis
1.70 1.03e-02 GO:0042330 taxis
1.83 1.03e-02 GO:0043009 chordate embryonic development
1.56 1.10e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.78 1.12e-02 GO:0016477 cell migration
1.23 1.23e-02 GO:0071840 cellular component organization or biogenesis
1.78 1.32e-02 GO:0009968 negative regulation of signal transduction
1.55 1.41e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.70 1.44e-02 GO:0001775 cell activation
1.66 1.45e-02 GO:0006928 cellular component movement
1.81 1.50e-02 GO:0009792 embryo development ending in birth or egg hatching
1.33 1.51e-02 GO:0048583 regulation of response to stimulus
1.69 1.56e-02 GO:0048585 negative regulation of response to stimulus
1.44 1.66e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.80 1.81e-02 GO:0060429 epithelium development
1.91 1.88e-02 GO:0048729 tissue morphogenesis
1.72 2.06e-02 GO:0048870 cell motility
1.72 2.06e-02 GO:0051674 localization of cell
1.73 2.07e-02 GO:0023057 negative regulation of signaling
1.50 2.10e-02 GO:0006351 transcription, DNA-dependent
1.73 2.25e-02 GO:0010648 negative regulation of cell communication
1.81 2.30e-02 GO:0007420 brain development
1.51 2.31e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.50 2.70e-02 GO:0009888 tissue development
1.92 2.77e-02 GO:0051960 regulation of nervous system development
1.50 2.98e-02 GO:0009891 positive regulation of biosynthetic process
1.79 3.03e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
2.38 3.60e-02 GO:0048705 skeletal system morphogenesis
3.16 3.74e-02 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.39 3.83e-02 GO:0051239 regulation of multicellular organismal process
2.27 4.51e-02 GO:0001655 urogenital system development
6.75 4.71e-02 GO:0021602 cranial nerve morphogenesis
3.11 4.83e-02 GO:0048704 embryonic skeletal system morphogenesis
1.39 4.88e-02 GO:0009893 positive regulation of metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 1.80e-04 GO:0005634 nucleus
1.20 2.48e-03 GO:0005886 plasma membrane
1.19 3.86e-03 GO:0071944 cell periphery
1.28 5.41e-03 GO:0044459 plasma membrane part
1.68 1.43e-02 GO:0043005 neuron projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.06 9.66e-13 GO:0043565 sequence-specific DNA binding
1.85 1.97e-12 GO:0001071 nucleic acid binding transcription factor activity
1.85 1.97e-12 GO:0003700 sequence-specific DNA binding transcription factor activity
1.47 2.24e-10 GO:0003677 DNA binding
1.69 2.53e-08 GO:0030528 transcription regulator activity
1.08 5.08e-04 GO:0005488 binding
1.25 5.77e-04 GO:0003676 nucleic acid binding
3.53 1.46e-03 GO:0003707 steroid hormone receptor activity
3.34 3.55e-03 GO:0004879 ligand-dependent nuclear receptor activity
1.13 4.32e-03 GO:0005515 protein binding
1.44 8.45e-03 GO:0005102 receptor binding
3.45 3.08e-02 GO:0003823 antigen binding