Motif ID: PPARG.p2

Z-value: 1.427


Transcription factors associated with PPARG.p2:

Gene SymbolEntrez IDGene Name
PPARG 5468 peroxisome proliferator-activated receptor gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PPARGchr3_+_12367993-0.591.7e-02Click!


Activity profile for motif PPARG.p2.

activity profile for motif PPARG.p2


Sorted Z-values histogram for motif PPARG.p2

Sorted Z-values for motif PPARG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PPARG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_60432443 5.789 NM_173804
TMEM86B
transmembrane protein 86B
chr2_+_218992053 4.960 NM_007127
VIL1
villin 1
chr19_-_55708936 3.885 NM_001114598
ASPDH
aspartate dehydrogenase domain containing
chr8_+_145692916 3.273 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr10_+_114125927 3.232 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_114125955 2.801 ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_114126004 2.708 ACSL5
acyl-CoA synthetase long-chain family member 5
chr8_-_145613058 2.609 NM_130849
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr8_-_145613034 2.190 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr19_-_5821546 2.033 NM_002034
FUT5
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr16_+_88696172 2.015 FAM157C
family with sequence similarity 157, member C
chr1_-_94359266 1.956 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr1_+_201541241 1.776 BTG2
BTG family, member 2
chr20_-_62081434 1.722 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr19_-_5790702 1.562 NM_000150
NM_001040701
FUT6

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

chr15_-_38908197 1.506 NM_001130143
NM_017726
PPP1R14D

protein phosphatase 1, regulatory (inhibitor) subunit 14D

chr11_+_46697312 1.495 NM_000506
F2
coagulation factor II (thrombin)
chr11_+_46697335 1.477 F2
coagulation factor II (thrombin)
chr19_-_13074669 1.463 LYL1
lymphoblastic leukemia derived sequence 1
chr17_-_59451662 1.370 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr14_+_23855291 1.262 LTB4R
leukotriene B4 receptor
chr7_-_128330615 1.226 KCP
kielin/chordin-like protein
chr19_+_54708389 1.219 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_-_4491024 1.202 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr7_+_128367961 1.185 NM_001098627
IRF5
interferon regulatory factor 5
chr16_-_28425632 1.179 NM_145659
IL27
interleukin 27
chr11_+_46697345 1.176 F2
coagulation factor II (thrombin)
chr1_-_204455269 1.111 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr22_+_21006814 1.111


chr1_+_201541269 1.107 NM_006763
BTG2
BTG family, member 2
chr10_-_72032519 1.070 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr19_-_4491078 1.040 LRG1
leucine-rich alpha-2-glycoprotein 1
chr19_+_40321567 1.022 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr11_+_66927976 1.011 NM_198517
TBC1D10C
TBC1 domain family, member 10C
chr7_-_99365178 1.011 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr6_+_7053863 0.995 RREB1
ras responsive element binding protein 1
chr22_-_21814208 0.989 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr7_-_156161130 0.957


chr9_+_139245029 0.950 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr16_-_3567354 0.898 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr11_+_384199 0.830 NM_007183
PKP3
plakophilin 3
chr17_+_39603599 0.810 NM_080863
ASB16
ankyrin repeat and SOCS box containing 16
chr6_-_28999388 0.775 TRIM27
tripartite motif containing 27
chr19_+_18312365 0.771 NM_017712
FKBP8
PGPEP1
FK506 binding protein 8, 38kDa
pyroglutamyl-peptidase I
chr21_-_10120690 0.766 NM_001187
NM_182484
NM_181704
NM_182481
NM_182482
BAGE
BAGE5
BAGE4
BAGE3
BAGE2
B melanoma antigen
B melanoma antigen family, member 5
B melanoma antigen family, member 4
B melanoma antigen family, member 3
B melanoma antigen family, member 2
chr7_-_92057597 0.760 NM_001040057
NM_152789
FAM133B

family with sequence similarity 133, member B

chr3_-_110319598 0.756 NM_014429
MORC1
MORC family CW-type zinc finger 1
chr19_+_40321584 0.747 FXYD1
FXYD domain containing ion transport regulator 1
chrX_+_105823723 0.730 NM_024539
RNF128
ring finger protein 128
chr16_+_1143241 0.714 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr17_+_75319476 0.712 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr11_+_2880135 0.696 SLC22A18
solute carrier family 22, member 18
chr1_-_37991160 0.692 EPHA10
EPH receptor A10
chr19_-_13074973 0.679 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr2_+_112612429 0.667 NM_001128165
NM_153214
FBLN7

fibulin 7

chr12_+_56135353 0.641 NM_031479
INHBE
inhibin, beta E
chr6_-_52549774 0.635 NM_012288
TRAM2
translocation associated membrane protein 2
chr17_+_16259573 0.613 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr7_-_92057561 0.608 FAM133B
family with sequence similarity 133, member B
chr5_+_156628929 0.608 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr19_+_1442000 0.603 NM_138393
REEP6
receptor accessory protein 6
chr8_-_145672525 0.598 NM_003923
FOXH1
forkhead box H1
chr11_+_66927955 0.596 TBC1D10C
TBC1 domain family, member 10C
chr5_-_179951071 0.586 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr17_+_42641712 0.585 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr2_-_89223666 0.568 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr22_+_21042091 0.557 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr19_+_951295 0.555 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr19_+_53650577 0.554 NM_013348
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr5_-_179040580 0.552 NM_001164444
CBY3
chibby homolog 3 (Drosophila)
chr17_-_35331435 0.543 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr11_+_66499323 0.526 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr11_+_2880104 0.515 SLC22A18
solute carrier family 22, member 18
chr11_-_67528103 0.511 NM_030930
UNC93B1
unc-93 homolog B1 (C. elegans)
chr5_+_133870175 0.511


chr19_-_44060729 0.506 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr17_-_37590910 0.495 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr10_-_11976704 0.493 LOC219731
hypothetical LOC219731
chr8_-_27392647 0.490 NM_000742
CHRNA2
cholinergic receptor, nicotinic, alpha 2 (neuronal)
chr11_+_303852 0.486 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr11_+_384238 0.483 PKP3
plakophilin 3
chr12_-_94914133 0.472 NM_002108
HAL
histidine ammonia-lyase
chr2_+_112612511 0.449 FBLN7
fibulin 7
chr16_-_4105703 0.449 ADCY9
adenylate cyclase 9
chr8_+_144802972 0.444 NM_014789
ZNF623
zinc finger protein 623
chr1_-_150029529 0.439 NM_001083963
NM_001083964
NM_001083965
NM_006862
TDRKH



tudor and KH domain containing



chr1_-_149955870 0.433 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr7_-_97868362 0.425 NM_018842
BAIAP2L1
BAI1-associated protein 2-like 1
chr22_+_20880159 0.416 IGLV6-57
immunoglobulin lambda variable 6-57
chrX_+_70360184 0.411 GJB1
gap junction protein, beta 1, 32kDa
chr17_+_7474177 0.408 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr9_-_135140450 0.407 NM_020469
ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr19_-_54636425 0.404 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr16_+_82782223 0.402 NM_001145400
NM_139174
ADAD2

adenosine deaminase domain containing 2

chr17_-_59327602 0.401 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr2_+_47021866 0.401 TTC7A
tetratricopeptide repeat domain 7A
chr17_-_71747867 0.398 NM_052916
RNF157
ring finger protein 157
chr16_+_84204424 0.398 NM_014615
KIAA0182
KIAA0182
chr11_+_65049152 0.396 SCYL1
SCY1-like 1 (S. cerevisiae)
chr3_-_172227152 0.391 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr4_-_176970407 0.391 GPM6A
glycoprotein M6A
chr9_-_135140425 0.390 ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr19_-_61396232 0.389 NM_001080456
ZSCAN5B
zinc finger and SCAN domain containing 5B
chr5_-_176869943 0.384 NM_001144875
NM_001144876
DOK3

docking protein 3

chr4_-_176970372 0.384 GPM6A
glycoprotein M6A
chr19_-_14085979 0.383 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr19_-_14447163 0.380 NM_000955
PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr11_+_65049102 0.380 NM_001048218
NM_020680
SCYL1

SCY1-like 1 (S. cerevisiae)

chr19_+_1389397 0.375 RPS15
ribosomal protein S15
chr22_+_21094094 0.374


chr6_+_132901119 0.372 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr14_-_74458897 0.371 NM_031464
RPS6KL1
ribosomal protein S6 kinase-like 1
chr6_-_31736488 0.368 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr1_-_159099090 0.364 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr17_-_70401299 0.358 NM_178128
FADS6
fatty acid desaturase domain family, member 6
chr7_+_150390566 0.358 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr17_-_31231421 0.354 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr14_+_105024301 0.354 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr17_+_16259636 0.352 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr9_-_130006309 0.351 NM_001131015
NM_012127
CIZ1

CDKN1A interacting zinc finger protein 1

chr19_-_55763091 0.346 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr11_+_64079665 0.341 NM_018484
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr20_+_33593191 0.341 NM_015966
NM_198398
ERGIC3

ERGIC and golgi 3

chr1_-_3806683 0.340 NM_207356
C1orf174
chromosome 1 open reading frame 174
chr1_-_154665807 0.340 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr19_+_7874701 0.336 MAP2K7
mitogen-activated protein kinase kinase 7
chr9_+_138966588 0.335 NM_178536
LCN12
lipocalin 12
chr10_-_72032447 0.335 PRF1
perforin 1 (pore forming protein)
chr22_+_20880112 0.330


chr16_+_80626459 0.329 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr1_-_6448737 0.323 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr20_+_33593243 0.320 ERGIC3
ERGIC and golgi 3
chr7_-_100262971 0.317 NM_004444
EPHB4
EPH receptor B4
chr1_+_26389638 0.317 NM_198137
CATSPER4
cation channel, sperm associated 4
chr1_+_559618 0.317


chr15_-_74390861 0.315 NM_000126
NM_001127716
ETFA

electron-transfer-flavoprotein, alpha polypeptide

chr2_+_231569082 0.314 NM_139073
SPATA3
spermatogenesis associated 3
chr16_+_19375272 0.312 NM_024780
TMC5
transmembrane channel-like 5
chr11_+_9736408 0.308 LOC283104
hypothetical LOC283104
chr1_-_120112989 0.307 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr19_+_16860807 0.305 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr7_-_38341697 0.304 TRGV7
T cell receptor gamma variable 7 pseudogene
chr1_-_3806564 0.304 C1orf174
chromosome 1 open reading frame 174
chr11_+_7463175 0.303 NM_198474
OLFML1
olfactomedin-like 1
chr3_-_129777618 0.300 NM_007354
C3orf27
chromosome 3 open reading frame 27
chr22_+_21484240 0.299


chr17_-_36981830 0.299 NM_000226
KRT9
keratin 9
chr1_+_165225121 0.299 NM_032858
MAEL
maelstrom homolog (Drosophila)
chr3_+_33815081 0.295 PDCD6IP
programmed cell death 6 interacting protein
chr3_+_33815097 0.294 PDCD6IP
programmed cell death 6 interacting protein
chr19_-_45141473 0.293 LOC440525
PRR13
proline rich 13 pseudogene
proline rich 13
chr1_+_205992032 0.289 CD46
CD46 molecule, complement regulatory protein
chr10_-_99042419 0.282 ARHGAP19
Rho GTPase activating protein 19
chr2_+_27200160 0.277 NM_032604
ABHD1
abhydrolase domain containing 1
chr8_-_143864933 0.274 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chr21_-_42644138 0.271 NM_005423
TFF2
trefoil factor 2
chr22_-_35113797 0.267 MYH9
myosin, heavy chain 9, non-muscle
chr17_-_39340414 0.266 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr19_+_56337368 0.264 NM_014385
NM_016543
SIGLEC7

sialic acid binding Ig-like lectin 7

chr10_+_102748062 0.262 LZTS2
leucine zipper, putative tumor suppressor 2
chr20_-_33705244 0.261 NM_003915
CPNE1
copine I
chr7_-_128337997 0.256 NM_001135914
NM_199349
KCP

kielin/chordin-like protein

chr20_+_33593247 0.255 ERGIC3
ERGIC and golgi 3
chr5_+_78443357 0.253 NM_001713
BHMT
betaine--homocysteine S-methyltransferase
chr6_-_52549673 0.252 TRAM2
translocation associated membrane protein 2
chr12_+_119391982 0.250 NM_001037494
DYNLL1
dynein, light chain, LC8-type 1
chr17_+_72883759 0.249 NM_001113494
SEPT9
septin 9
chr1_-_149955415 0.246 NM_001172648
NM_001172649
CELF3

CUGBP, Elav-like family member 3

chr4_+_2764609 0.246 SH3BP2
SH3-domain binding protein 2
chr22_-_35113947 0.244 MYH9
myosin, heavy chain 9, non-muscle
chr2_-_200030944 0.233 NM_001172509
SATB2
SATB homeobox 2
chr2_+_233927880 0.232 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr22_-_35113923 0.230 MYH9
myosin, heavy chain 9, non-muscle
chr1_+_205992004 0.230 NM_002389
NM_153826
NM_172350
NM_172351
NM_172352
NM_172353
NM_172359
NM_172361
CD46







CD46 molecule, complement regulatory protein







chr2_+_119697859 0.229 STEAP3
STEAP family member 3
chr8_+_144888275 0.228 LOC100128338
hypothetical LOC100128338
chr2_+_47021816 0.225 NM_020458
TTC7A
tetratricopeptide repeat domain 7A
chr14_+_23700261 0.225 NM_006084
IRF9
interferon regulatory factor 9
chr19_+_54530512 0.224 CD37
CD37 molecule
chr11_-_65424436 0.223 NM_005438
FOSL1
FOS-like antigen 1
chr9_-_33437527 0.222 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr19_+_54708312 0.221 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr9_-_37582575 0.220 NM_001001790
NM_001134484
NM_001134485
TOMM5


translocase of outer mitochondrial membrane 5 homolog (yeast)


chr19_+_54708247 0.218 NM_004107
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_+_2880063 0.214 NM_002555
SLC22A18
solute carrier family 22, member 18
chr1_-_51757490 0.212 EPS15
epidermal growth factor receptor pathway substrate 15
chr19_-_54618410 0.211 NM_178449
PTH2
parathyroid hormone 2
chr9_-_135232735 0.206 SURF4
surfeit 4
chr17_+_55139644 0.203 NM_030938
VMP1
vacuole membrane protein 1
chr7_-_97868101 0.203 BAIAP2L1
BAI1-associated protein 2-like 1
chr1_+_45542138 0.203 LOC400752
hypothetical LOC400752
chr9_-_91284430 0.201 NM_001142287
NM_006378
SEMA4D

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

chr10_-_99042381 0.198 NM_032900
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 read-through transcript
Rho GTPase activating protein 19
chr22_+_18388602 0.198 NM_152906
C22orf25
chromosome 22 open reading frame 25
chr16_+_65579988 0.197 NM_173815
CES4A
carboxylesterase 4A
chr1_-_41259973 0.196 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr11_+_2881080 0.192 SLC22A18
solute carrier family 22, member 18
chr19_-_41091023 0.191 TYROBP
TYRO protein tyrosine kinase binding protein
chr19_-_60350122 0.190 TNNT1
troponin T type 1 (skeletal, slow)
chr6_-_43585958 0.188 C6orf154
chromosome 6 open reading frame 154

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.75 1.69e-03 GO:0044459 plasma membrane part
1.90 2.34e-02 GO:0005887 integral to plasma membrane
1.87 3.41e-02 GO:0031226 intrinsic to plasma membrane
6.74 4.92e-02 GO:0005793 ER-Golgi intermediate compartment

Nothing significant found in function category.