Motif ID: SMAD1..7,9.p2

Z-value: 2.705


Transcription factors associated with SMAD1..7,9.p2:

Gene SymbolEntrez IDGene Name
SMAD1 4086 SMAD family member 1
SMAD2 4087 SMAD family member 2
SMAD3 4088 SMAD family member 3
SMAD4 4089 SMAD family member 4
SMAD5 4090 SMAD family member 5
SMAD6 4091 SMAD family member 6
SMAD7 4092 SMAD family member 7
SMAD9 4093 SMAD family member 9

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMAD6chr15_+_647817230.638.7e-03Click!
SMAD4chr18_+_46810598-0.591.7e-02Click!
SMAD3chr15_+_651452150.504.8e-02Click!
SMAD2chr18_-_43710917-0.504.9e-02Click!
SMAD9chr13_-_363923700.322.3e-01Click!
SMAD7chr18_-_447231160.282.9e-01Click!
SMAD5chr5_+_1354964210.263.2e-01Click!
SMAD1chr4_+_146622154-0.048.9e-01Click!


Activity profile for motif SMAD1..7,9.p2.

activity profile for motif SMAD1..7,9.p2


Sorted Z-values histogram for motif SMAD1..7,9.p2

Sorted Z-values for motif SMAD1..7,9.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1..7,9.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_30151526 4.307 NM_170769
NM_025236
 RNF39

ring finger protein 39

chr15_-_40236061 2.533 NM_213600
 PLA2G4F
phospholipase A2, group IVF
chr19_+_40299058 2.456 FXYD3
FXYD domain containing ion transport regulator 3
chr19_-_48976852 2.453 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr19_-_17275083 2.340 NM_024527
 ABHD8
abhydrolase domain containing 8
chr1_-_43523825 2.278 NM_182517
NM_001164829
 C1orf210

chromosome 1 open reading frame 210

chr11_+_66580884 2.187 RHOD
ras homolog gene family, member D
chr16_+_82959626 2.186 NM_014861
 ATP2C2
ATPase, Ca++ transporting, type 2C, member 2
chr1_+_232416618 2.164 SLC35F3
solute carrier family 35, member F3
chr12_-_121780835 2.097 NM_032554
 GPR81
G protein-coupled receptor 81
chr1_-_26553168 2.034 NM_001039775
 AIM1L
absent in melanoma 1-like
chr1_-_6368324 1.977 NM_181864
 ACOT7
acyl-CoA thioesterase 7
chr1_+_144439069 1.945 NM_002614
 PDZK1
PDZ domain containing 1
chr2_-_108972100 1.899 NM_022336
 EDAR
ectodysplasin A receptor
chr9_+_139239464 1.894 NM_199001
 C9orf169
chromosome 9 open reading frame 169
chr11_-_65860450 1.878 NM_004292
 RIN1
Ras and Rab interactor 1
chrX_+_152682772 1.856 NM_001163257
NM_005393
 PLXNB3

plexin B3

chr22_+_23221114 1.842 NM_016327
 UPB1
ureidopropionase, beta
chr19_-_48977247 1.841 NM_002250
 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr17_-_67628523 1.825 FLJ37644
hypothetical LOC400618

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
2.17 2.43e-02 GO:0030817 regulation of cAMP biosynthetic process
2.15 3.02e-02 GO:0030814 regulation of cAMP metabolic process
2.12 2.24e-02 GO:0030802 regulation of cyclic nucleotide biosynthetic process
2.12 2.24e-02 GO:0030808 regulation of nucleotide biosynthetic process
2.07 4.13e-02 GO:0030799 regulation of cyclic nucleotide metabolic process
1.82 1.03e-02 GO:0050767 regulation of neurogenesis
1.76 2.76e-03 GO:0060284 regulation of cell development
1.71 1.36e-02 GO:0007610 behavior
1.56 2.51e-04 GO:0045595 regulation of cell differentiation
1.53 3.25e-02 GO:0007599 hemostasis
1.52 8.42e-03 GO:0042060 wound healing
1.51 2.08e-02 GO:0050878 regulation of body fluid levels
1.50 1.41e-04 GO:0048699 generation of neurons
1.49 1.42e-03 GO:2000026 regulation of multicellular organismal development
1.48 1.48e-04 GO:0022008 neurogenesis
1.48 8.10e-03 GO:0030182 neuron differentiation
1.47 2.70e-04 GO:0050793 regulation of developmental process
1.46 1.10e-06 GO:0051239 regulation of multicellular organismal process
1.45 1.18e-03 GO:0009611 response to wounding
1.41 2.37e-03 GO:0007154 cell communication

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.93 3.72e-03 GO:0070161 anchoring junction
1.85 3.94e-02 GO:0005912 adherens junction
1.51 9.74e-04 GO:0030054 cell junction
1.31 6.02e-03 GO:0005887 integral to plasma membrane
1.31 7.29e-03 GO:0031226 intrinsic to plasma membrane
1.29 1.32e-05 GO:0044459 plasma membrane part
1.20 3.77e-06 GO:0071944 cell periphery
1.20 5.92e-06 GO:0005886 plasma membrane
1.13 1.18e-05 GO:0016020 membrane
1.12 2.64e-03 GO:0044425 membrane part

Nothing significant found in function category.