Motif ID: SPI1.p2

Z-value: 3.456


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_473566420.711.9e-03Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_35586950 6.694 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr16_-_87570716 6.292 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr11_+_63864263 5.869 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr1_+_159899528 5.332 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr10_+_49562866 4.628 WDFY4
WDFY family member 4
chrX_-_47374187 4.397 NM_001145252
CFP
complement factor properdin
chr11_+_65164767 4.253 SIPA1
signal-induced proliferation-associated 1
chr16_-_29664765 4.140 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr12_-_55929189 4.038


chr1_-_26517342 3.895 NM_145345
UBXN11
UBX domain protein 11
chr1_+_159817752 3.865 NM_201563
FCGR2C
Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr6_-_32268267 3.706 GPSM3
G-protein signaling modulator 3
chr17_-_44058612 3.479 NM_024017
HOXB9
homeobox B9
chr1_+_26517032 3.353 CD52
CD52 molecule
chr7_+_106292932 3.286 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_106292975 3.278 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr12_-_53071285 3.165 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr17_+_44643067 3.159 ABI3
ABI family, member 3
chr1_+_26517045 3.154 CD52
CD52 molecule
chr19_-_10311262 3.118 NM_002162
ICAM3
intercellular adhesion molecule 3
chrX_-_47374647 3.067 NM_002621
CFP
complement factor properdin
chr17_-_40843530 3.059 ARHGAP27
Rho GTPase activating protein 27
chr17_+_44642587 2.979 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr14_+_20319049 2.918 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr16_+_28413421 2.850 NM_018690
APOBR
apolipoprotein B receptor
chr17_-_31441390 2.843 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr7_+_101715110 2.760 NM_020979
SH2B2
SH2B adaptor protein 2
chr1_-_31003260 2.758 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr6_-_32268615 2.735 GPSM3
G-protein signaling modulator 3
chr14_-_22354457 2.712 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr19_-_7672978 2.708 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr7_+_101715137 2.650 SH2B2
SH2B adaptor protein 2
chr12_-_51887266 2.632 NM_000889
ITGB7
integrin, beta 7
chr12_-_53664722 2.606 NM_001136030
KIAA0748
KIAA0748
chr1_+_111544469 2.597


chr6_+_31648071 2.579 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr16_+_56134077 2.555 NM_153837
GPR114
G protein-coupled receptor 114
chr16_+_56134037 2.421 GPR114
G protein-coupled receptor 114
chr2_+_143603439 2.421 ARHGAP15
Rho GTPase activating protein 15
chr14_-_22354389 2.419 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chrX_+_48427103 2.414 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chrX_+_48427137 2.411 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr22_+_42908612 2.407 PARVG
parvin, gamma
chr1_-_111544603 2.388


chr2_+_108604111 2.383 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr12_+_25096472 2.358 NM_006152
LRMP
lymphoid-restricted membrane protein
chr9_+_263025 2.357 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr19_+_14412052 2.342 PKN1
protein kinase N1
chr19_+_14412087 2.325 PKN1
protein kinase N1
chr12_-_50004102 2.315 BIN2
bridging integrator 2
chr19_+_14412080 2.314 NM_213560
PKN1
protein kinase N1
chr2_+_143603368 2.311 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr11_+_66927976 2.291 NM_198517
TBC1D10C
TBC1 domain family, member 10C
chr19_-_55091942 2.270 NM_152899
IL4I1
interleukin 4 induced 1
chrX_+_72699834 2.241 CHIC1
cysteine-rich hydrophobic domain 1
chr12_-_50004172 2.230 NM_016293
BIN2
bridging integrator 2
chr3_-_113334657 2.212 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr12_-_50004208 2.208 BIN2
bridging integrator 2
chr1_-_111544784 2.203 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr17_-_24491521 2.163 MYO18A
myosin XVIIIA
chr12_+_48443232 2.121 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr1_+_111217314 2.104 CD53
CD53 molecule
chr22_+_35639564 2.104 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr6_+_31647854 2.100 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr1_-_111544820 2.099 DENND2D
DENN/MADD domain containing 2D
chr11_+_66927955 2.095 TBC1D10C
TBC1 domain family, member 10C
chr2_-_231498184 2.091 NM_005683
GPR55
G protein-coupled receptor 55
chr1_+_111217244 2.077 NM_000560
CD53
CD53 molecule
chr19_-_6432765 2.061 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr6_+_31661934 2.038 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr6_+_31662454 2.037 NM_205837
LST1
leukocyte specific transcript 1
chr2_+_241213334 1.961 NM_005301
GPR35
G protein-coupled receptor 35
chr12_+_53241365 1.937 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr12_-_51887318 1.932 ITGB7
integrin, beta 7
chr16_-_87297525 1.920 NM_001171816
RNF166
ring finger protein 166
chr11_+_107304344 1.908 NM_017516
RAB39
RAB39, member RAS oncogene family
chr10_+_26767698 1.907 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr12_-_53153613 1.895 GTSF1
gametocyte specific factor 1
chr1_-_17318452 1.869 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr16_+_30583278 1.868 NM_001105079
FBRS
fibrosin
chr12_-_53153639 1.867 NM_144594
GTSF1
gametocyte specific factor 1
chr7_-_3049872 1.866 NM_032415
CARD11
caspase recruitment domain family, member 11
chr19_-_13074973 1.865 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr1_-_181826292 1.859 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr19_-_43800374 1.854 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr9_-_129580732 1.853 NM_170600
SH2D3C
SH2 domain containing 3C
chr17_-_44642934 1.852 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr5_-_88215034 1.816 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr19_-_8548297 1.813 MYO1F
myosin IF
chr19_-_43608641 1.805 NM_001146202
NM_001146203
NM_001146204
NM_001146205
NM_001146206
NM_001146207
NM_170604
RASGRP4






RAS guanyl releasing protein 4






chr5_+_140871107 1.804


chr19_+_40895669 1.802 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr5_-_169657192 1.801 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr22_-_35970230 1.801 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_-_8548232 1.798 MYO1F
myosin IF
chr22_-_16080265 1.795 CECR1
cat eye syndrome chromosome region, candidate 1
chr17_-_59363352 1.794 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr19_+_41085221 1.785 NM_001007469
NM_014266
HCST

hematopoietic cell signal transducer

chr11_+_65164167 1.781 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr12_-_56422120 1.773 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr7_+_106293112 1.740 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr11_+_122936246 1.734 GRAMD1B
GRAM domain containing 1B
chr6_+_31651319 1.731 NM_000594
TNF
tumor necrosis factor
chr12_+_55018925 1.729 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr1_-_159306037 1.727 ARHGAP30
Rho GTPase activating protein 30
chr19_-_13074669 1.719 LYL1
lymphoblastic leukemia derived sequence 1
chr5_-_176869440 1.711 DOK3
docking protein 3
chrX_-_153632355 1.704 NM_001081573
NM_080612
GAB3

GRB2-associated binding protein 3

chr19_-_46504831 1.701


chr5_-_169657312 1.701 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr16_+_29582065 1.699 SPN
sialophorin
chr16_+_29582069 1.697 NM_003123
SPN
sialophorin
chr11_-_66961709 1.690 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr7_+_73826244 1.679 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr6_-_33016561 1.678 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr17_+_31455332 1.667 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr22_-_35970133 1.665 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_-_15436333 1.663 NM_022904
RASAL3
RAS protein activator like 3
chr1_-_31003181 1.662 LAPTM5
lysosomal protein transmembrane 5
chr9_-_129707392 1.659 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_+_207995999 1.638 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr6_+_43846735 1.627 VEGFA
vascular endothelial growth factor A
chr2_-_175207521 1.623 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr5_-_169657360 1.621 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr2_+_68445936 1.619 PLEK
pleckstrin
chr5_-_169657395 1.612 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr19_+_59866217 1.610 LILRB4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
chr1_-_181826086 1.588 NCF2
neutrophil cytosolic factor 2
chr3_+_195889845 1.588 FAM43A
family with sequence similarity 43, member A
chr2_+_68445821 1.587 NM_002664
PLEK
pleckstrin
chr1_+_26516967 1.582 NM_001803
CD52
CD52 molecule
chr16_+_48865521 1.581 ADCY7
adenylate cyclase 7
chr1_-_92124064 1.577 TGFBR3
transforming growth factor, beta receptor III
chr1_-_21375939 1.576 NM_001198801
NM_001198802
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr6_+_37511383 1.572


chr19_+_54530497 1.554 CD37
CD37 molecule
chr22_+_23153529 1.547 NM_000675
ADORA2A
adenosine A2a receptor
chr12_-_53065758 1.546 ZNF385A
zinc finger protein 385A
chr22_-_28992787 1.544 NM_020530
OSM
oncostatin M
chr5_-_176869943 1.536 NM_001144875
NM_001144876
DOK3

docking protein 3

chr1_-_158883666 1.535 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr12_+_25096755 1.524 LRMP
lymphoid-restricted membrane protein
chr12_-_56159631 1.523 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr8_+_145158432 1.509 NM_001134374
NM_198572
SPATC1

spermatogenesis and centriole associated 1

chr5_-_88016397 1.499 LOC645323
hypothetical LOC645323
chr22_-_36212160 1.497 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr8_+_126511739 1.478 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr11_+_46339691 1.473 NM_001105540
DGKZ
diacylglycerol kinase, zeta
chr2_+_169637255 1.471 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr11_+_122936145 1.465 GRAMD1B
GRAM domain containing 1B
chr7_-_4867963 1.461 NM_020144
PAPOLB
poly(A) polymerase beta (testis specific)
chr19_-_40925151 1.446 NM_024660
TMEM149
transmembrane protein 149
chr4_+_91035025 1.444 NM_007351
MMRN1
multimerin 1
chr17_-_35975227 1.437 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr19_-_55008172 1.434 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr15_-_76313896 1.434 NM_015162
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr10_-_75080784 1.419 NM_024875
SYNPO2L
synaptopodin 2-like
chr14_-_22354851 1.409 NM_001126105
NM_003982
SLC7A7

solute carrier family 7 (cationic amino acid transporter, y+ system), member 7

chr12_+_6930815 1.408 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr10_+_26767657 1.404 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr3_-_114176401 1.403 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr19_-_55104875 1.400 NUP62
nucleoporin 62kDa
chr16_-_30301634 1.398 NM_052838
SEPT1
septin 1
chr21_-_45165204 1.393 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr21_-_45165302 1.382 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr16_+_27320983 1.381 NM_181078
NM_181079
IL21R

interleukin 21 receptor

chr17_+_53769562 1.374 LOC100506779
hypothetical LOC100506779
chr22_-_30071761 1.374 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr22_+_23333610 1.373 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr7_+_149895390 1.373 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr10_-_71002998 1.371 NM_020999
NEUROG3
neurogenin 3
chr1_-_158815895 1.370 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr6_+_37081387 1.367 NM_173558
FGD2
FYVE, RhoGEF and PH domain containing 2
chr16_+_29582480 1.360 SPN
sialophorin
chr20_+_30019465 1.357 NM_001011718
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr21_-_45165249 1.354 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_+_149309703 1.352 NM_144618
GABPB2
GA binding protein transcription factor, beta subunit 2
chr1_-_205161821 1.343 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr3_-_122862447 1.339 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr17_+_53769659 1.321 LOC100506779
hypothetical LOC100506779
chr12_-_53661888 1.320 NM_001098815
KIAA0748
KIAA0748
chr3_-_122862391 1.318 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr22_+_42908548 1.300 PARVG
parvin, gamma
chr1_-_158815850 1.291 CD84
CD84 molecule
chr11_-_46099531 1.288 NM_001101802
NM_016621
PHF21A

PHD finger protein 21A

chr22_+_42908589 1.287 NM_001137606
PARVG
parvin, gamma
chr7_-_81237162 1.281 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr7_+_150065376 1.280 NM_018384
GIMAP5
GTPase, IMAP family member 5
chr5_-_142795269 1.275 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chrX_-_70248022 1.271 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr1_+_154386358 1.271 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr7_+_149779011 1.266 GIMAP8
GTPase, IMAP family member 8
chr1_-_159306327 1.266 ARHGAP30
Rho GTPase activating protein 30
chr7_+_128367961 1.266 NM_001098627
IRF5
interferon regulatory factor 5
chr12_-_56159895 1.253 NM_032496
ARHGAP9
Rho GTPase activating protein 9
chr6_+_73388713 1.245 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr6_-_6265896 1.241 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr7_-_44985202 1.230 NM_033054
MYO1G
myosin IG
chr12_-_8656705 1.229 NM_020661
AICDA
activation-induced cytidine deaminase
chr5_+_88220846 1.226



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 1.08e-13 GO:0050794 regulation of cellular process
1.12 1.15e-13 GO:0050789 regulation of biological process
1.12 2.12e-13 GO:0065007 biological regulation
1.08 4.68e-13 GO:0009987 cellular process
1.17 1.46e-11 GO:0044260 cellular macromolecule metabolic process
1.22 1.01e-10 GO:0048518 positive regulation of biological process
1.27 2.38e-10 GO:0048583 regulation of response to stimulus
1.22 1.12e-09 GO:0044267 cellular protein metabolic process
1.14 1.87e-09 GO:0043170 macromolecule metabolic process
1.22 2.98e-09 GO:0048522 positive regulation of cellular process
1.16 3.25e-09 GO:0051716 cellular response to stimulus
1.18 1.55e-08 GO:0007165 signal transduction
1.30 4.41e-08 GO:0002376 immune system process
1.24 6.82e-08 GO:0006464 protein modification process
1.25 1.91e-07 GO:0023051 regulation of signaling
1.22 3.49e-07 GO:0048523 negative regulation of cellular process
1.27 3.62e-07 GO:0009966 regulation of signal transduction
1.15 4.36e-07 GO:0023052 signaling
1.20 4.92e-07 GO:0048519 negative regulation of biological process
1.16 6.92e-07 GO:0031323 regulation of cellular metabolic process
1.14 1.39e-06 GO:0019222 regulation of metabolic process
1.26 2.30e-06 GO:0035556 intracellular signal transduction
1.45 2.54e-06 GO:0001775 cell activation
1.21 4.08e-06 GO:0043412 macromolecule modification
1.10 4.79e-06 GO:0044238 primary metabolic process
1.10 5.71e-06 GO:0044237 cellular metabolic process
1.16 6.57e-06 GO:0019538 protein metabolic process
1.14 1.97e-05 GO:0080090 regulation of primary metabolic process
1.22 3.31e-05 GO:0006996 organelle organization
1.32 9.68e-05 GO:0046907 intracellular transport
1.14 2.35e-04 GO:0060255 regulation of macromolecule metabolic process
1.45 2.47e-04 GO:0051056 regulation of small GTPase mediated signal transduction
1.14 3.28e-04 GO:0016043 cellular component organization
1.26 3.84e-04 GO:0043067 regulation of programmed cell death
1.25 3.86e-04 GO:0051649 establishment of localization in cell
1.27 4.02e-04 GO:0006793 phosphorus metabolic process
1.27 4.02e-04 GO:0006796 phosphate metabolic process
1.26 4.27e-04 GO:0042981 regulation of apoptosis
1.13 5.07e-04 GO:0071840 cellular component organization or biogenesis
1.32 5.37e-04 GO:0002682 regulation of immune system process
1.24 5.44e-04 GO:0031325 positive regulation of cellular metabolic process
1.26 6.03e-04 GO:0032268 regulation of cellular protein metabolic process
1.24 6.64e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.25 7.69e-04 GO:0051246 regulation of protein metabolic process
1.23 8.12e-04 GO:0009893 positive regulation of metabolic process
1.25 1.21e-03 GO:0010941 regulation of cell death
1.16 1.57e-03 GO:0006950 response to stress
1.15 1.58e-03 GO:0071842 cellular component organization at cellular level
1.52 1.63e-03 GO:0045321 leukocyte activation
1.29 1.75e-03 GO:0031399 regulation of protein modification process
1.35 1.89e-03 GO:0044265 cellular macromolecule catabolic process
1.36 1.97e-03 GO:0007599 hemostasis
1.34 2.37e-03 GO:0006928 cellular component movement
1.39 2.37e-03 GO:0007243 intracellular protein kinase cascade
1.39 2.37e-03 GO:0023014 signal transduction via phosphorylation event
1.28 2.40e-03 GO:0048584 positive regulation of response to stimulus
1.33 2.62e-03 GO:0050878 regulation of body fluid levels
1.37 2.91e-03 GO:0050776 regulation of immune response
1.31 3.80e-03 GO:0051726 regulation of cell cycle
1.22 3.83e-03 GO:0051641 cellular localization
1.07 4.28e-03 GO:0008152 metabolic process
1.14 5.11e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.35 5.16e-03 GO:0007596 blood coagulation
1.35 5.16e-03 GO:0050817 coagulation
1.20 5.83e-03 GO:0065009 regulation of molecular function
1.18 6.18e-03 GO:0016070 RNA metabolic process
1.62 6.67e-03 GO:0050900 leukocyte migration
1.29 8.05e-03 GO:0019220 regulation of phosphate metabolic process
1.29 8.05e-03 GO:0051174 regulation of phosphorus metabolic process
1.48 9.68e-03 GO:0030097 hemopoiesis
1.23 9.91e-03 GO:0010646 regulation of cell communication
1.08 1.01e-02 GO:0050896 response to stimulus
1.77 1.04e-02 GO:0050851 antigen receptor-mediated signaling pathway
1.53 1.31e-02 GO:0046649 lymphocyte activation
1.39 1.33e-02 GO:0016568 chromatin modification
1.13 1.38e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 1.49e-02 GO:0002684 positive regulation of immune system process
1.35 1.62e-02 GO:0043069 negative regulation of programmed cell death
1.23 1.66e-02 GO:0009892 negative regulation of metabolic process
1.44 1.80e-02 GO:0048534 hemopoietic or lymphoid organ development
1.36 1.85e-02 GO:0016477 cell migration
1.48 1.88e-02 GO:0030168 platelet activation
1.25 1.98e-02 GO:0016310 phosphorylation
1.42 2.17e-02 GO:0002520 immune system development
1.15 2.20e-02 GO:0090304 nucleic acid metabolic process
1.16 2.46e-02 GO:0007166 cell surface receptor linked signaling pathway
1.29 2.67e-02 GO:0009057 macromolecule catabolic process
1.24 2.77e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.26 3.14e-02 GO:0016192 vesicle-mediated transport
1.22 3.25e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.34 3.51e-02 GO:0043066 negative regulation of apoptosis
1.23 3.60e-02 GO:0042127 regulation of cell proliferation
1.25 3.61e-02 GO:0006955 immune response
1.27 3.74e-02 GO:0042325 regulation of phosphorylation
1.31 3.75e-02 GO:0016071 mRNA metabolic process
1.33 4.29e-02 GO:0048870 cell motility
1.33 4.29e-02 GO:0051674 localization of cell
1.20 4.78e-02 GO:0050790 regulation of catalytic activity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 1.01e-13 GO:0005622 intracellular
1.07 1.24e-13 GO:0044424 intracellular part
1.04 4.25e-11 GO:0005623 cell
1.04 5.61e-11 GO:0044464 cell part
1.09 4.86e-10 GO:0005737 cytoplasm
1.13 4.93e-10 GO:0005634 nucleus
1.22 1.06e-08 GO:0005829 cytosol
1.17 1.28e-07 GO:0043234 protein complex
1.08 1.45e-07 GO:0043227 membrane-bounded organelle
1.08 1.53e-07 GO:0043231 intracellular membrane-bounded organelle
1.11 3.31e-07 GO:0044446 intracellular organelle part
1.20 4.16e-07 GO:0044428 nuclear part
1.11 7.11e-07 GO:0044422 organelle part
1.07 1.12e-06 GO:0043229 intracellular organelle
1.06 1.63e-06 GO:0043226 organelle
1.14 2.58e-06 GO:0032991 macromolecular complex
1.09 8.93e-05 GO:0044444 cytoplasmic part
1.43 1.24e-04 GO:0048471 perinuclear region of cytoplasm
1.18 1.94e-04 GO:0031981 nuclear lumen
1.20 1.40e-03 GO:0005654 nucleoplasm
1.27 1.69e-03 GO:0044451 nucleoplasm part
1.14 2.79e-03 GO:0043233 organelle lumen
1.14 3.71e-03 GO:0031974 membrane-enclosed lumen
1.12 7.57e-03 GO:0043228 non-membrane-bounded organelle
1.12 7.57e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.13 1.20e-02 GO:0070013 intracellular organelle lumen
1.16 1.22e-02 GO:0012505 endomembrane system
1.80 2.67e-02 GO:0030117 membrane coat
1.80 2.67e-02 GO:0048475 coated membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 4.46e-28 GO:0005515 protein binding
1.05 2.43e-07 GO:0005488 binding
1.45 3.81e-07 GO:0060589 nucleoside-triphosphatase regulator activity
1.46 5.46e-07 GO:0030695 GTPase regulator activity
1.55 3.01e-05 GO:0005096 GTPase activator activity
1.30 1.14e-04 GO:0019899 enzyme binding
1.40 4.24e-04 GO:0008047 enzyme activator activity
1.44 8.87e-04 GO:0016564 transcription repressor activity
1.25 8.98e-04 GO:0030234 enzyme regulator activity
1.23 1.74e-03 GO:0030528 transcription regulator activity
1.44 2.19e-03 GO:0005083 small GTPase regulator activity
1.38 2.56e-03 GO:0003712 transcription cofactor activity
1.38 3.09e-03 GO:0000988 protein binding transcription factor activity
1.38 3.09e-03 GO:0000989 transcription factor binding transcription factor activity
1.14 8.69e-03 GO:0000166 nucleotide binding
1.14 4.10e-02 GO:0032553 ribonucleotide binding
1.14 4.10e-02 GO:0032555 purine ribonucleotide binding
1.14 4.31e-02 GO:0017076 purine nucleotide binding
1.14 4.76e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.65 4.88e-02 GO:0005099 Ras GTPase activator activity