Motif ID: SPZ1.p2

Z-value: 1.259


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_79651545-0.077.9e-01Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_199130571 1.309 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr16_-_66535457 1.223 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr17_+_72795567 1.151 NM_001113492
SEPT9
septin 9
chr6_-_116488458 1.135 NM_002031
FRK
fyn-related kinase
chrX_+_105856531 1.097 NM_194463
RNF128
ring finger protein 128
chr2_-_36384 1.025 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr16_+_29819647 0.975 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr20_-_30535045 0.935 C20orf112
chromosome 20 open reading frame 112
chr2_-_220144254 0.922 OBSL1
obscurin-like 1
chr10_-_101680645 0.905 DNMBP
dynamin binding protein
chr17_-_77824849 0.900 NM_001893
NM_139062
CSNK1D

casein kinase 1, delta

chr16_+_56211410 0.899 NM_001145770
NM_005682
GPR56

G protein-coupled receptor 56

chr1_+_27541086 0.898 SYTL1
synaptotagmin-like 1
chr20_-_22513050 0.865 NM_021784
FOXA2
forkhead box A2
chr18_-_26935883 0.858 NM_004949
NM_024422
DSC2

desmocollin 2

chr14_-_22974707 0.800 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr16_+_67236730 0.798 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr17_+_45965044 0.791 NM_017957
EPN3
epsin 3
chr17_-_37144408 0.787 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1


chr20_-_42457717 0.782


chr16_+_67236699 0.781 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr16_+_56211150 0.768 GPR56
G protein-coupled receptor 56
chr17_+_33761234 0.751 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr1_-_150070849 0.750 NM_005060
RORC
RAR-related orphan receptor C
chr5_+_129268352 0.749 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr14_-_22596522 0.744 NM_022478
NM_144985
CDH24

cadherin 24, type 2

chr6_-_30151526 0.720 NM_170769
NM_025236
RNF39

ring finger protein 39

chr4_-_118226119 0.698 NM_152402
TRAM1L1
translocation associated membrane protein 1-like 1
chr20_-_22514092 0.690 NM_153675
FOXA2
forkhead box A2
chr2_-_219633481 0.688 NM_002181
IHH
Indian hedgehog
chr19_+_40431678 0.687 LSR
lipolysis stimulated lipoprotein receptor
chr16_-_66535923 0.686 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr12_+_39372456 0.677 NM_001843
NM_175038
CNTN1

contactin 1

chr17_-_40858775 0.671 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr3_+_125786195 0.664 NM_007064
KALRN
kalirin, RhoGEF kinase
chr16_+_29373365 0.654 NM_001014999
NM_001015000
NM_024044
NM_178044
SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr14_+_23937766 0.646 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr9_+_135389698 0.641 NM_014694
ADAMTSL2
ADAMTS-like 2
chr7_+_45894480 0.635 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr2_-_42873179 0.635 NM_012205
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
chr2_+_242400702 0.633 NM_001167599
NM_001167602
NM_080741
NEU4


sialidase 4


chr20_-_9767406 0.631 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr11_+_12987455 0.623 NM_001080521
RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr11_-_70641267 0.618 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr14_-_24588916 0.611 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr9_+_115957537 0.606 COL27A1
collagen, type XXVII, alpha 1
chr12_-_52980914 0.598 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr13_-_33148899 0.598 STARD13
StAR-related lipid transfer (START) domain containing 13
chr16_-_4778317 0.593 NM_001154458
NM_144605
SEPT12

septin 12

chr17_+_45405128 0.590 NM_001934
DLX4
distal-less homeobox 4
chr16_-_31054321 0.587 PRSS8
protease, serine, 8
chr17_+_71582486 0.584 NM_003857
GALR2
galanin receptor 2
chr3_-_150858274 0.582 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr20_+_31334601 0.577 NM_033197
C20orf114
chromosome 20 open reading frame 114
chr1_-_24307514 0.565 MYOM3
myomesin family, member 3
chr12_+_48784057 0.565 NM_005276
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr1_-_150079656 0.556 NM_001136003
C2CD4D
C2 calcium-dependent domain containing 4D
chr10_-_105411339 0.552 SH3PXD2A
SH3 and PX domains 2A
chr2_-_165186232 0.548 GRB14
growth factor receptor-bound protein 14
chr16_+_65765256 0.543 NM_003946
NM_001185057
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr6_-_31954730 0.542 SLC44A4
solute carrier family 44, member 4
chr11_-_2116775 0.538 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr7_-_142816019 0.538 NM_005232
EPHA1
EPH receptor A1
chr13_+_92677012 0.536 NM_005708
GPC6
glypican 6
chr12_+_64504835 0.534 HMGA2
high mobility group AT-hook 2
chr20_-_22512893 0.534 FOXA2
forkhead box A2
chr3_+_214668 0.533


chr7_-_20791907 0.532


chr3_-_184316553 0.531 MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr16_-_49742008 0.529 NM_001127892
SALL1
sal-like 1 (Drosophila)
chr2_-_165186603 0.529 NM_004490
GRB14
growth factor receptor-bound protein 14
chr1_-_159459999 0.528 NM_001643
APOA2
apolipoprotein A-II
chr5_+_137829077 0.526 NM_001964
EGR1
early growth response 1
chr15_-_81412354 0.525 NM_004839
NM_199330
NM_199331
NM_199332
HOMER2



homer homolog 2 (Drosophila)



chr4_-_15694407 0.522 PROM1
prominin 1
chr1_-_151855413 0.519 NM_020672
S100A14
S100 calcium binding protein A14
chr14_-_22516271 0.516 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr16_+_2954217 0.510 NM_024507
NM_172229
KREMEN2

kringle containing transmembrane protein 2

chr9_+_676640 0.508


chr12_+_106236281 0.506 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr14_+_89597860 0.506 NM_022054
KCNK13
potassium channel, subfamily K, member 13
chr17_-_74231266 0.503 CYTH1
cytohesin 1
chr22_+_29122932 0.500 NM_012429
NM_033382
SEC14L2

SEC14-like 2 (S. cerevisiae)

chr12_-_49878216 0.495 NM_002702
POU6F1
POU class 6 homeobox 1
chr6_+_31538934 0.495 NM_006674
HCP5
HLA complex P5
chr1_+_27541049 0.494 NM_001193308
NM_032872
SYTL1

synaptotagmin-like 1

chr12_-_47468985 0.494 NM_020983
ADCY6
adenylate cyclase 6
chr17_-_67628523 0.494 FLJ37644
hypothetical LOC400618
chr20_-_17610704 0.493 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr11_-_116168316 0.493 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr6_+_6670117 0.491


chr12_-_193516 0.491 NM_001122848
SLC6A12
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr18_-_22383066 0.486 NM_001136205
KCTD1
potassium channel tetramerisation domain containing 1
chr16_-_31054563 0.486 NM_002773
PRSS8
protease, serine, 8
chr19_+_45973139 0.484 NM_006533
MIA
melanoma inhibitory activity
chr11_+_45900731 0.482 GYLTL1B
glycosyltransferase-like 1B
chr1_-_224143389 0.481 NM_020997
LEFTY1
left-right determination factor 1
chr14_+_70178126 0.481 NM_015351
TTC9
tetratricopeptide repeat domain 9
chr16_+_12902955 0.480 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr9_-_106705867 0.478 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr8_-_144726064 0.477 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr12_+_48652886 0.476 NM_001652
AQP6
aquaporin 6, kidney specific
chr5_+_79021401 0.468 NM_153610
CMYA5
cardiomyopathy associated 5
chr19_-_6671585 0.463 NM_000064
C3
complement component 3
chrX_-_107866262 0.458 NM_003604
IRS4
insulin receptor substrate 4
chr16_-_49742651 0.456 NM_002968
SALL1
sal-like 1 (Drosophila)
chr14_+_36196523 0.456 NM_006194
PAX9
paired box 9
chr17_+_69939806 0.453 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chrX_-_20044670 0.451 NM_001168467
MAP7D2
MAP7 domain containing 2
chr2_+_70981223 0.450 NM_012476
VAX2
ventral anterior homeobox 2
chr10_-_71753684 0.449 LRRC20
leucine rich repeat containing 20
chr6_-_24466258 0.448 NM_016356
DCDC2
doublecortin domain containing 2
chr20_+_20296744 0.447 NM_002196
INSM1
insulinoma-associated 1
chr6_+_43036442 0.446 NM_018960
GNMT
glycine N-methyltransferase
chr12_+_439803 0.443 NM_173593
B4GALNT3
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr10_+_123862430 0.443 TACC2
transforming, acidic coiled-coil containing protein 2
chr22_-_44751671 0.442 NM_058238
WNT7B
wingless-type MMTV integration site family, member 7B
chr6_+_32090516 0.438 NM_007293
NM_001002029
C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr1_-_21868380 0.437 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr19_+_6415259 0.437 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr2_-_165186064 0.437 GRB14
growth factor receptor-bound protein 14
chr15_-_71448194 0.434 HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr15_-_72804763 0.431 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr3_+_152287365 0.430 NM_053002
MED12L
mediator complex subunit 12-like
chr16_-_51138306 0.429 NM_001080430
TOX3
TOX high mobility group box family member 3
chr7_+_100156358 0.429 NM_000799
EPO
erythropoietin
chr1_+_15955719 0.428 FBLIM1
filamin binding LIM protein 1
chr8_-_144887876 0.428 NM_198488
FAM83H
family with sequence similarity 83, member H
chr6_+_41714171 0.427 NM_005586
MDFI
MyoD family inhibitor
chr15_-_68933481 0.426 NM_018357
NM_197958
LARP6

La ribonucleoprotein domain family, member 6

chr1_+_199127242 0.422 NM_018265
C1orf106
chromosome 1 open reading frame 106
chr16_-_28425632 0.421 NM_145659
IL27
interleukin 27
chr15_-_71448657 0.420 NM_005477
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr7_-_96492064 0.419 NM_005221
DLX5
distal-less homeobox 5
chr2_-_139254273 0.418 NM_007226
NXPH2
neurexophilin 2
chr2_+_70981233 0.418 VAX2
ventral anterior homeobox 2
chr4_-_120768563 0.416 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr9_-_106705780 0.415 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr17_+_35425139 0.411 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chrX_-_106033202 0.409 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr17_-_36469869 0.408 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr10_-_118419459 0.408 NM_144661
C10orf82
chromosome 10 open reading frame 82
chr9_-_85342868 0.407 NM_174938
FRMD3
FERM domain containing 3
chr11_-_8788765 0.402 NM_213618
ST5
suppression of tumorigenicity 5
chr6_+_30082331 0.402 HLA-J
major histocompatibility complex, class I, J (pseudogene)
chr3_+_10832867 0.401 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr3_-_9265592 0.401 SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr19_+_49972965 0.400 NM_001130852
NM_012116
CBLC

Cas-Br-M (murine) ecotropic retroviral transforming sequence c

chr11_+_62893836 0.400 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr4_-_1156362 0.396 SPON2
spondin 2, extracellular matrix protein
chr19_+_40223249 0.395 NM_002151
NM_182983
HPN

hepsin

chr1_+_57093030 0.394 NM_000562
C8A
complement component 8, alpha polypeptide
chr20_-_61933012 0.393 ZBTB46
zinc finger and BTB domain containing 46
chr14_-_76677711 0.390 ZDHHC22
zinc finger, DHHC-type containing 22
chr20_+_3399615 0.385 NM_139321
NM_139322
ATRN

attractin

chr6_-_18230829 0.384 NM_198586
NHLRC1
NHL repeat containing 1
chr20_-_17610828 0.384 NM_001042576
NM_004587
RRBP1

ribosome binding protein 1 homolog 180kDa (dog)

chr1_+_24755152 0.383 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr14_-_23781607 0.381 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr5_-_134899537 0.379 NM_006161
NEUROG1
neurogenin 1
chr2_+_219532590 0.379 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr9_-_4289574 0.379 GLIS3
GLIS family zinc finger 3
chr3_-_187562470 0.378 NM_001080744
NM_001080745
NM_001346
DGKG


diacylglycerol kinase, gamma 90kDa


chr14_-_20636337 0.378 ZNF219
zinc finger protein 219
chr7_-_99411573 0.377 NM_001185
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chrX_-_132376660 0.376 NM_001448
GPC4
glypican 4
chr21_-_36774257 0.376 NM_001146079
NM_144492
CLDN14

claudin 14

chr5_+_5193442 0.376 NM_139056
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chrX_-_132947290 0.375 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chr2_-_86889029 0.374 NM_001145873
CD8A
CD8a molecule
chr9_+_70926009 0.371 NM_001170414
TJP2
tight junction protein 2 (zona occludens 2)
chr12_-_24606616 0.366 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr19_+_39664706 0.366 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr11_-_124127343 0.364 VSIG2
V-set and immunoglobulin domain containing 2
chr1_+_46418786 0.364 TSPAN1
tetraspanin 1
chrX_-_132947141 0.363 GPC3
glypican 3
chr14_-_23686269 0.363 PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr11_-_124127295 0.363 NM_014312
VSIG2
V-set and immunoglobulin domain containing 2
chr9_+_111582317 0.360 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr17_-_35017650 0.360 NEUROD2
neurogenic differentiation 2
chr15_+_58083798 0.360 FOXB1
forkhead box B1
chr12_+_47658502 0.359 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr16_+_54247042 0.358 NM_001172501
SLC6A2
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chrX_-_54401161 0.357 NM_001002838
NM_020922
WNK3

WNK lysine deficient protein kinase 3

chr14_+_23527866 0.356 NM_198083
DHRS4
DHRS4L2
dehydrogenase/reductase (SDR family) member 4
dehydrogenase/reductase (SDR family) member 4 like 2
chr19_-_63715135 0.355 NM_012254
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr2_-_218843109 0.354 NM_001087
AAMP
angio-associated, migratory cell protein
chr20_+_1824006 0.353 SIRPA
signal-regulatory protein alpha
chr3_+_85090721 0.351 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr22_+_18330049 0.351 NM_007310
COMT
catechol-O-methyltransferase
chr17_-_36928604 0.350 NM_002275
KRT15
keratin 15
chr18_-_23019176 0.350 NM_031422
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr20_-_581844 0.350 NM_080725
SRXN1
sulfiredoxin 1
chr3_+_187840842 0.349 NM_014375
FETUB
fetuin B
chr6_+_160689355 0.345 NM_021977
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr2_+_219779737 0.344 NM_138802
ZFAND2B
zinc finger, AN1-type domain 2B
chr2_-_26058941 0.343 NM_002254
KIF3C
kinesin family member 3C
chr17_+_45993338 0.343 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr16_-_14695930 0.343 NM_003561
PLA2G10
phospholipase A2, group X
chr11_-_124127244 0.340 VSIG2
V-set and immunoglobulin domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.42 3.16e-12 GO:0007399 nervous system development
1.40 3.74e-11 GO:0009653 anatomical structure morphogenesis
1.21 2.58e-09 GO:0032502 developmental process
1.24 6.73e-09 GO:0048856 anatomical structure development
1.22 8.34e-09 GO:0007275 multicellular organismal development
1.25 1.00e-08 GO:0048731 system development
1.49 1.34e-08 GO:0048699 generation of neurons
1.47 1.60e-08 GO:0022008 neurogenesis
1.29 5.76e-08 GO:0030154 cell differentiation
1.28 1.05e-07 GO:0048869 cellular developmental process
1.50 5.83e-07 GO:0030182 neuron differentiation
1.19 2.07e-06 GO:0023052 signaling
1.50 4.92e-06 GO:0032989 cellular component morphogenesis
1.11 1.40e-05 GO:0050794 regulation of cellular process
1.55 1.42e-05 GO:0000904 cell morphogenesis involved in differentiation
1.40 1.61e-05 GO:0050793 regulation of developmental process
1.39 1.63e-05 GO:0048468 cell development
1.38 2.49e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.49 2.90e-05 GO:0000902 cell morphogenesis
1.42 3.16e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.99 3.64e-05 GO:0045165 cell fate commitment
1.33 5.16e-05 GO:0031325 positive regulation of cellular metabolic process
1.30 5.40e-05 GO:0009966 regulation of signal transduction
1.44 6.08e-05 GO:0045595 regulation of cell differentiation
1.21 6.28e-05 GO:0048518 positive regulation of biological process
1.32 6.42e-05 GO:0009893 positive regulation of metabolic process
1.47 6.86e-05 GO:0009887 organ morphogenesis
1.42 7.12e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 1.16e-04 GO:0023051 regulation of signaling
1.10 1.19e-04 GO:0050789 regulation of biological process
1.10 1.55e-04 GO:0065007 biological regulation
1.43 1.69e-04 GO:0010628 positive regulation of gene expression
1.42 2.06e-04 GO:0009790 embryo development
1.40 2.12e-04 GO:2000026 regulation of multicellular organismal development
1.82 2.20e-04 GO:0048732 gland development
1.44 2.63e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.32 3.04e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.46 3.53e-04 GO:0048666 neuron development
1.21 3.56e-04 GO:0048522 positive regulation of cellular process
1.52 3.91e-04 GO:0048812 neuron projection morphogenesis
1.48 5.33e-04 GO:0048858 cell projection morphogenesis
1.48 5.50e-04 GO:0032990 cell part morphogenesis
1.42 6.91e-04 GO:0030030 cell projection organization
1.51 7.70e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.06 7.78e-04 GO:0009987 cellular process
1.36 8.57e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.70 9.11e-04 GO:0045995 regulation of embryonic development
1.16 1.08e-03 GO:0007165 signal transduction
1.38 1.25e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.98 1.40e-03 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.40 1.57e-03 GO:0051254 positive regulation of RNA metabolic process
2.40 1.91e-03 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
1.46 2.31e-03 GO:0031175 neuron projection development
1.50 2.93e-03 GO:0007409 axonogenesis
1.53 3.46e-03 GO:0048598 embryonic morphogenesis
1.34 3.50e-03 GO:0009891 positive regulation of biosynthetic process
2.03 4.10e-03 GO:0030323 respiratory tube development
2.05 4.32e-03 GO:0030278 regulation of ossification
1.65 4.69e-03 GO:0003002 regionalization
1.22 4.97e-03 GO:0048583 regulation of response to stimulus
1.33 8.19e-03 GO:0051128 regulation of cellular component organization
2.73 1.18e-02 GO:0035272 exocrine system development
2.00 1.25e-02 GO:0030324 lung development
1.26 1.27e-02 GO:0051239 regulation of multicellular organismal process
1.14 1.28e-02 GO:0031323 regulation of cellular metabolic process
1.79 1.54e-02 GO:0001655 urogenital system development
1.14 1.59e-02 GO:0080090 regulation of primary metabolic process
1.11 1.79e-02 GO:0032501 multicellular organismal process
1.56 2.11e-02 GO:0035295 tube development
1.88 2.13e-02 GO:0060541 respiratory system development
1.50 2.51e-02 GO:0007389 pattern specification process
1.41 2.51e-02 GO:0007417 central nervous system development
2.32 2.53e-02 GO:0045667 regulation of osteoblast differentiation
1.52 2.73e-02 GO:0060284 regulation of cell development
1.45 3.31e-02 GO:0009968 negative regulation of signal transduction
2.43 3.35e-02 GO:0048663 neuron fate commitment
2.09 3.72e-02 GO:2000027 regulation of organ morphogenesis
1.52 3.91e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.41 4.78e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.54 2.83e-08 GO:0030054 cell junction
1.80 2.21e-04 GO:0070161 anchoring junction
1.50 3.49e-04 GO:0043005 neuron projection
1.48 9.69e-04 GO:0045202 synapse
1.31 1.41e-03 GO:0042995 cell projection
1.78 1.58e-03 GO:0005912 adherens junction
1.22 3.10e-03 GO:0005856 cytoskeleton
1.18 3.74e-03 GO:0044459 plasma membrane part
2.82 5.17e-03 GO:0001725 stress fiber
1.43 1.58e-02 GO:0031012 extracellular matrix
2.63 1.84e-02 GO:0032432 actin filament bundle
2.53 2.16e-02 GO:0042641 actomyosin
1.46 3.51e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 1.87e-09 GO:0005515 protein binding
1.37 5.23e-06 GO:0001071 nucleic acid binding transcription factor activity
1.37 5.23e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.33 1.31e-04 GO:0030528 transcription regulator activity
1.38 6.90e-04 GO:0043565 sequence-specific DNA binding
1.41 1.53e-03 GO:0008092 cytoskeletal protein binding
1.05 2.94e-03 GO:0005488 binding
1.48 1.44e-02 GO:0016563 transcription activator activity