Motif ID: TFCP2.p2

Z-value: 4.343


Transcription factors associated with TFCP2.p2:

Gene SymbolEntrez IDGene Name
TFCP2 7024 transcription factor CP2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFCP2chr12_-_49852858-0.894.1e-06Click!


Activity profile for motif TFCP2.p2.

activity profile for motif TFCP2.p2


Sorted Z-values histogram for motif TFCP2.p2

Sorted Z-values for motif TFCP2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFCP2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_70641267 4.195 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr6_+_36206239 3.982 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr20_+_8060762 3.247 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr20_-_30636535 3.063 LOC284804
hypothetical protein LOC284804
chr17_-_959007 3.035 NM_001092
ABR
active BCR-related gene
chr16_+_56211410 3.006 NM_001145770
NM_005682
GPR56

G protein-coupled receptor 56

chr9_-_6635564 2.962 NM_000170
GLDC
glycine dehydrogenase (decarboxylating)
chr17_-_40866062 2.948 NM_174919
SH3D20
SH3 domain containing 20
chr16_+_56211150 2.944 GPR56
G protein-coupled receptor 56
chr17_-_40865987 2.840 SH3D20
SH3 domain containing 20
chr14_+_76717880 2.830 TMEM63C
transmembrane protein 63C
chr20_+_51023159 2.786 TSHZ2
teashirt zinc finger homeobox 2
chr17_+_56831951 2.760 NM_005994
TBX2
T-box 2
chr1_-_40555413 2.758 COL9A2
collagen, type IX, alpha 2
chr17_+_56832255 2.757 TBX2
T-box 2
chr6_-_37773609 2.742 NM_153487
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr2_-_95189231 2.688 ZNF514
zinc finger protein 514
chr20_-_29921983 2.659 NM_080611
DUSP15
C20orf57
dual specificity phosphatase 15
chromosome 20 open reading frame 57
chr19_+_44697592 2.544 NM_182704
SELV
selenoprotein V
chr2_+_42128521 2.539 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr19_-_15869870 2.532 NM_001082
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr20_-_29921671 2.523 NM_177991
DUSP15
dual specificity phosphatase 15
chr20_+_29922165 2.473 NM_001008409
TTLL9
tubulin tyrosine ligase-like family, member 9
chr17_-_71023048 2.449 CASKIN2
CASK interacting protein 2
chr19_+_15612706 2.438 NM_000896
CYP4F3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr5_+_76542461 2.401 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr2_-_36384 2.391 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr17_-_71023221 2.387 NM_020753
CASKIN2
CASK interacting protein 2
chr12_-_55168168 2.352 NM_013267
GLS2
glutaminase 2 (liver, mitochondrial)
chr20_-_29921461 2.223 NM_001012644
DUSP15
dual specificity phosphatase 15
chr17_+_43403475 2.189 CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr17_+_43403466 2.170 CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr2_-_73373956 2.165 NM_001965
EGR4
early growth response 4
chr19_-_11390948 2.165 NM_001035223
NM_001161616
RGL3

ral guanine nucleotide dissociation stimulator-like 3

chr14_-_99842519 2.078 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr11_-_407324 2.067 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr3_+_197427779 2.043 NM_152672
OSTalpha
organic solute transporter alpha
chr5_-_7904255 2.021 NM_001089584
C5orf49
chromosome 5 open reading frame 49
chr17_+_43403405 2.014 NM_176096
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr17_+_42283946 1.995 NM_003396
WNT9B
wingless-type MMTV integration site family, member 9B
chr5_+_175725050 1.910 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr13_-_27572646 1.905 NM_004119
FLT3
fms-related tyrosine kinase 3
chr14_-_20562962 1.892 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr16_+_67328805 1.876 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr8_-_53640520 1.867 NM_207413
FAM150A
family with sequence similarity 150, member A
chr14_+_76717835 1.863 NM_020431
TMEM63C
transmembrane protein 63C
chrX_-_154341451 1.853 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr14_-_38971049 1.852 FBXO33
F-box protein 33
chrX_+_152644385 1.845 ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr3_-_198240969 1.840 MFI2
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr5_-_746413 1.833 NM_007030
TPPP
tubulin polymerization promoting protein
chr17_+_56832492 1.831 TBX2
T-box 2
chr8_-_22044463 1.811 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr2_-_42873179 1.803 NM_012205
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
chr9_-_115877104 1.793 AMBP
alpha-1-microglobulin/bikunin precursor
chr20_+_42417752 1.793 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr2_-_20288108 1.791 NM_002997
SDC1
syndecan 1
chr17_+_1574782 1.764 NM_001163809
WDR81
WD repeat domain 81
chrX_+_128942435 1.743


chr17_-_6958773 1.724 NM_001181
NM_080912
NM_080913
ASGR2


asialoglycoprotein receptor 2


chr16_+_65526845 1.714 CES2
carboxylesterase 2
chr5_-_180564716 1.713 NM_033342
NM_203293
TRIM7

tripartite motif containing 7

chr3_+_61522922 1.671 PTPRG
protein tyrosine phosphatase, receptor type, G
chr17_+_77574476 1.664 NM_144999
LRRC45
leucine rich repeat containing 45
chr17_-_17050355 1.655 NM_178836
PLD6
phospholipase D family, member 6
chr3_+_139636111 1.652 ESYT3
extended synaptotagmin-like protein 3
chr17_+_71892538 1.644 SPHK1
sphingosine kinase 1
chr11_+_110675175 1.638 NM_001136105
C11orf93
chromosome 11 open reading frame 93
chr15_+_78858763 1.638 NM_018689
KIAA1199
KIAA1199
chr1_-_110950497 1.631 KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr17_-_60208083 1.616 LOC146880
hypothetical LOC146880
chr3_+_160964574 1.613 SCHIP1
schwannomin interacting protein 1
chr11_-_75056761 1.612 MAP6
microtubule-associated protein 6
chr1_-_1131795 1.604 NM_004195
NM_148901
NM_148902
TNFRSF18


tumor necrosis factor receptor superfamily, member 18


chr14_-_106282128 1.598 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_-_6958695 1.590 ASGR2
asialoglycoprotein receptor 2
chr17_-_6958282 1.588 NM_080914
ASGR2
asialoglycoprotein receptor 2
chr3_+_139636104 1.580 NM_031913
ESYT3
extended synaptotagmin-like protein 3
chr16_-_21439195 1.561 SLC7A5P2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 pseudogene 2
chr16_-_56389176 1.561 NM_001130099
KIFC3
kinesin family member C3
chr17_-_17340219 1.548 NM_016084
RASD1
RAS, dexamethasone-induced 1
chr20_-_61933012 1.548 ZBTB46
zinc finger and BTB domain containing 46
chr7_-_149669622 1.533 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr19_+_38376980 1.521 LRP3
low density lipoprotein receptor-related protein 3
chr18_+_46340400 1.520 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr1_-_40027097 1.520 BMP8B
bone morphogenetic protein 8b
chr9_-_138778780 1.519 NM_203347
LCN15
lipocalin 15
chr1_-_40027108 1.518 NM_001720
BMP8B
bone morphogenetic protein 8b
chr11_+_65311142 1.504 OVOL1
ovo-like 1(Drosophila)
chr10_-_88116181 1.501 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chrX_+_68641802 1.501 NM_015686
FAM155B
family with sequence similarity 155, member B
chr11_+_75157414 1.498 NM_032564
DGAT2
diacylglycerol O-acyltransferase 2
chr22_+_33792125 1.494 NM_001008494
ISX
intestine-specific homeobox
chr17_-_17050326 1.491 PLD6
phospholipase D family, member 6
chr14_-_23727826 1.489 IPO4
importin 4
chr17_+_43165608 1.485 NM_013351
TBX21
T-box 21
chr2_+_109729176 1.485 NM_023016
ANKRD57
ankyrin repeat domain 57
chr11_-_65841077 1.475 NM_020404
CD248
CD248 molecule, endosialin
chr4_+_8251818 1.470 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr1_+_116455898 1.467 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr17_+_1574583 1.465 NM_001163811
WDR81
WD repeat domain 81
chr1_+_110554836 1.464 NM_001039574
NM_004978
KCNC4

potassium voltage-gated channel, Shaw-related subfamily, member 4

chr11_-_72170533 1.456 STARD10
StAR-related lipid transfer (START) domain containing 10
chr11_-_2116048 1.455 IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_+_38719371 1.445 NM_145041
TMEM106A
FLJ77644
transmembrane protein 106A
hypothetical LOC728772
chr14_+_68796621 1.439 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr9_+_68671800 1.435 NM_001098805
ANKRD20A4
ANKRD20A1
ankyrin repeat domain 20 family, member A4
ankyrin repeat domain 20 family, member A1
chr8_+_63324053 1.432 NM_173688
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr2_-_95188989 1.426 NM_032788
ZNF514
zinc finger protein 514
chr20_+_61337679 1.409 NM_022161
NM_139317
BIRC7

baculoviral IAP repeat containing 7

chr11_+_120399966 1.409 NM_001130047
NM_152715
TBCEL

tubulin folding cofactor E-like

chr1_-_224143389 1.403 NM_020997
LEFTY1
left-right determination factor 1
chr12_+_122812994 1.400 NM_207437
DNAH10
dynein, axonemal, heavy chain 10
chr16_-_66535923 1.400 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chrX_+_153767803 1.397 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr2_-_210798232 1.396 NM_001608
ACADL
acyl-CoA dehydrogenase, long chain
chr2_-_219633481 1.395 NM_002181
IHH
Indian hedgehog
chr17_+_45404677 1.393 DLX4
distal-less homeobox 4
chr13_-_49597776 1.392 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr9_-_119217147 1.392 ASTN2
astrotactin 2
chr11_+_46311314 1.390 NM_201532
DGKZ
diacylglycerol kinase, zeta
chr2_+_220200530 1.390 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr5_-_131375148 1.388 NM_001009185
NM_015256
ACSL6

acyl-CoA synthetase long-chain family member 6

chr3_+_32408346 1.386 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr6_-_88932485 1.386 NM_001160226
NM_001160258
NM_001160259
NM_016083
CNR1



cannabinoid receptor 1 (brain)



chr16_-_65516919 1.382 NM_001128850
NM_004165
RRAD

Ras-related associated with diabetes

chr19_-_4289750 1.381 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr16_-_66251611 1.375 ACD
adrenocortical dysplasia homolog (mouse)
chr11_-_900793 1.373 CHID1
chitinase domain containing 1
chrX_+_152565849 1.372 DUSP9
dual specificity phosphatase 9
chr9_-_139068269 1.371 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr18_+_18969724 1.371 NM_001100619
CABLES1
Cdk5 and Abl enzyme substrate 1
chr12_+_47658502 1.369 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr7_+_128367961 1.368 NM_001098627
IRF5
interferon regulatory factor 5
chr14_-_23727850 1.365 NM_024658
IPO4
importin 4
chr8_+_59069522 1.362 NM_147189
FAM110B
family with sequence similarity 110, member B
chr22_-_37878394 1.358 NM_175709
CBX7
chromobox homolog 7
chr19_-_38485161 1.355


chr19_+_15644885 1.351 NM_023944
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr2_-_74522513 1.349 RTKN
rhotekin
chr5_-_37285160 1.347 NM_023073
C5orf42
chromosome 5 open reading frame 42
chr17_-_42250961 1.346 NM_030753
WNT3
wingless-type MMTV integration site family, member 3
chr2_-_20288647 1.344 NM_001006946
SDC1
syndecan 1
chr20_-_60415729 1.331 NM_031215
CABLES2
Cdk5 and Abl enzyme substrate 2
chr16_-_66535457 1.330 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr2_+_231610438 1.329 NM_001144994
C2orf72
chromosome 2 open reading frame 72
chr16_+_705080 1.328 NM_024042
METRN
meteorin, glial cell differentiation regulator
chr9_-_137531517 1.326 NM_001048265
NM_144654
C9orf116

chromosome 9 open reading frame 116

chr19_+_40223249 1.322 NM_002151
NM_182983
HPN

hepsin

chr1_+_152014391 1.319 NM_024330
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr9_+_139091759 1.319 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr19_+_3129735 1.318 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr22_-_22714230 1.315 NM_000853
GSTT1
glutathione S-transferase theta 1
chr9_+_139265533 1.314 NM_001004353
C9orf173
chromosome 9 open reading frame 173
chr19_-_15906669 1.303 NM_001128932
NM_021187
CYP4F11

cytochrome P450, family 4, subfamily F, polypeptide 11

chr22_+_44277354 1.303 NM_001996
NM_006485
NM_006486
NM_006487
FBLN1



fibulin 1



chr9_-_35640852 1.303 NM_014450
SIT1
signaling threshold regulating transmembrane adaptor 1
chr5_-_172594691 1.297 NM_001166175
NM_001166176
NM_004387
NKX2-5


NK2 transcription factor related, locus 5 (Drosophila)


chr16_+_70217564 1.285 NM_001017967
NM_052858
MARVELD3

MARVEL domain containing 3

chr20_+_61838389 1.284 NM_017806
LIME1
Lck interacting transmembrane adaptor 1
chr3_-_198241079 1.282 NM_033316
NM_005929
MFI2

antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5

chr3_+_134947573 1.280 NM_001063
TF
transferrin
chr17_+_7283412 1.276 NM_004112
FGF11
fibroblast growth factor 11
chr19_-_10311262 1.274 NM_002162
ICAM3
intercellular adhesion molecule 3
chr3_-_52463070 1.272 NM_003280
TNNC1
troponin C type 1 (slow)
chr16_+_3036682 1.269 NM_022468
MMP25
matrix metallopeptidase 25
chr1_+_1256585 1.266 NM_152228
TAS1R3
taste receptor, type 1, member 3
chr2_+_9532087 1.263 NM_001039613
IAH1
isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr2_-_128792515 1.258 NM_004807
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr17_+_75507750 1.255


chr16_+_66120205 1.252 NM_024519
NM_001193522
FAM65A

family with sequence similarity 65, member A

chr9_-_119217128 1.248 NM_014010
ASTN2
astrotactin 2
chr5_-_139402909 1.239 NRG2
neuregulin 2
chr19_-_19599973 1.236 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr5_-_176671437 1.235 MXD3
MAX dimerization protein 3
chr11_+_76455574 1.233 NM_004055
CAPN5
calpain 5
chr1_-_16355013 1.231 NM_004431
EPHA2
EPH receptor A2
chr14_-_59001603 1.230 GPR135
G protein-coupled receptor 135
chr7_-_139987044 1.229 DENND2A
DENN/MADD domain containing 2A
chr22_+_34266837 1.227


chr20_+_61838479 1.222 LIME1
Lck interacting transmembrane adaptor 1
chr7_-_100630912 1.208 NM_178176
MOGAT3
monoacylglycerol O-acyltransferase 3
chr11_+_65100074 1.208 NM_001099409
EHBP1L1
EH domain binding protein 1-like 1
chr17_-_71535076 1.205 NM_001988
EVPL
envoplakin
chr9_+_42358298 1.203 NM_001012419
NM_001012421
ANKRD20A3
ANKRD20A2
ANKRD20A1
ankyrin repeat domain 20 family, member A3
ankyrin repeat domain 20 family, member A2
ankyrin repeat domain 20 family, member A1
chr11_-_905057 1.201 NM_001142675
CHID1
chitinase domain containing 1
chr2_-_27339278 1.187 NM_003459
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr9_-_116190038 1.186 AKNA
AT-hook transcription factor
chr14_-_22596522 1.179 NM_022478
NM_144985
CDH24

cadherin 24, type 2

chr11_-_2116360 1.179 IGF2
insulin-like growth factor 2 (somatomedin A)
chr20_+_62181878 1.177 NM_000913
NM_182647
OPRL1

opiate receptor-like 1

chr14_-_59001804 1.174 NM_022571
GPR135
G protein-coupled receptor 135
chr1_+_152806874 1.165 NM_000748
CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr8_-_145613058 1.165 NM_130849
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr16_+_66121040 1.157 NM_001193523
FAM65A
family with sequence similarity 65, member A
chr1_-_925332 1.153 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr3_+_10832867 1.149 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr3_+_50281582 1.148 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr3_+_134947940 1.146 TF
transferrin
chr22_-_49317408 1.143 ODF3B
outer dense fiber of sperm tails 3B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.50 2.33e-09 GO:0050793 regulation of developmental process
1.52 1.04e-07 GO:2000026 regulation of multicellular organismal development
1.19 2.44e-06 GO:0023052 signaling
1.11 4.30e-06 GO:0065007 biological regulation
1.32 1.82e-05 GO:0009966 regulation of signal transduction
1.26 2.70e-05 GO:0030154 cell differentiation
1.29 3.17e-05 GO:0023051 regulation of signaling
1.46 4.84e-05 GO:0045595 regulation of cell differentiation
1.25 5.07e-05 GO:0048869 cellular developmental process
1.69 8.59e-05 GO:0022603 regulation of anatomical structure morphogenesis
1.30 1.11e-04 GO:0007399 nervous system development
1.11 1.21e-04 GO:0050789 regulation of biological process
1.37 1.28e-04 GO:0042127 regulation of cell proliferation
1.18 1.29e-04 GO:0007165 signal transduction
1.31 1.92e-04 GO:0051239 regulation of multicellular organismal process
1.17 2.22e-04 GO:0032502 developmental process
1.25 2.48e-04 GO:0048583 regulation of response to stimulus
1.10 6.34e-04 GO:0050794 regulation of cellular process
1.67 7.63e-04 GO:0035295 tube development
1.16 1.54e-03 GO:0007275 multicellular organismal development
1.35 2.39e-03 GO:0048699 generation of neurons
1.20 3.33e-03 GO:0048519 negative regulation of biological process
1.20 3.43e-03 GO:0042221 response to chemical stimulus
1.18 3.45e-03 GO:0048518 positive regulation of biological process
1.34 3.99e-03 GO:0022008 neurogenesis
1.14 4.25e-03 GO:0051716 cellular response to stimulus
1.21 4.27e-03 GO:0048523 negative regulation of cellular process
1.48 5.10e-03 GO:0051094 positive regulation of developmental process
1.17 1.06e-02 GO:0048731 system development
1.19 1.18e-02 GO:0048522 positive regulation of cellular process
1.55 1.33e-02 GO:0060284 regulation of cell development
1.22 1.67e-02 GO:0007166 cell surface receptor linked signaling pathway
1.69 1.86e-02 GO:0045664 regulation of neuron differentiation
1.25 2.64e-02 GO:0035556 intracellular signal transduction
1.15 2.78e-02 GO:0048856 anatomical structure development
1.26 3.01e-02 GO:0010033 response to organic substance
1.38 3.02e-02 GO:0009725 response to hormone stimulus
1.36 3.32e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.48 4.30e-02 GO:0043009 chordate embryonic development
1.55 4.43e-02 GO:0051960 regulation of nervous system development
1.35 4.70e-02 GO:0009719 response to endogenous stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 7.85e-03 GO:0005737 cytoplasm
1.08 1.21e-02 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.08 8.47e-03 GO:0005515 protein binding
1.39 4.11e-02 GO:0030695 GTPase regulator activity