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• Activity deltas table
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Motif ID: ZBTB16.p2

Z-value: 1.900

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_-_53444733	5.109	NM_001184901 NM_001184903 NM_014959	CARD8	caspase recruitment domain family, member 8
chr13_-_98708549	3.069	NM_001098200 NM_005292	GPR18	G protein-coupled receptor 18
chr2_+_161701711	3.039	NM_004180 NM_133484	TANK	TRAF family member-associated NFKB activator
chr12_-_51887318	2.894		ITGB7	integrin, beta 7
chr2_-_242205556	2.820	NM_001164356	THAP4	THAP domain containing 4
chr3_+_188197029	2.615
chr12_-_51887266	2.522	NM_000889	ITGB7	integrin, beta 7
chr4_-_38460983	2.176	NM_001017388 NM_001195106 NM_001195107 NM_001195108 NM_030956	TLR10	toll-like receptor 10
chr8_+_39890484	2.168	NM_002164	IDO1	indoleamine 2,3-dioxygenase 1
chr8_+_86287161	2.055	NM_001083589	E2F5	E2F transcription factor 5, p130-binding
chr12_+_121218218	1.889	NM_152759	LRRC43	leucine rich repeat containing 43
chr7_+_106293112	1.876	NM_002649	PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr19_+_14554895	1.874	NM_207390	CLEC17A	C-type lectin domain family 17, member A
chr13_-_40454360	1.853	NM_001145353	ELF1	E74-like factor 1 (ets domain transcription factor)
chr9_-_70780574	1.795
chr9_-_116196505	1.769	NM_030767	AKNA	AT-hook transcription factor
chr1_+_173111306	1.752	NM_001035230	RABGAP1L	RAB GTPase activating protein 1-like
chr2_-_231697999	1.751	NM_000867	HTR2B	5-hydroxytryptamine (serotonin) receptor 2B
chr10_-_11614279	1.660	NM_001080491	USP6NL	USP6 N-terminal like
chr21_+_29374743	1.652	NM_020152	C21orf7	chromosome 21 open reading frame 7
chr13_-_98757634	1.623	NM_004951	GPR183	G protein-coupled receptor 183
chr12_-_25041639	1.560	NM_001101339	C12orf77	chromosome 12 open reading frame 77
chr10_-_31328426	1.529	NM_001143769	ZNF438	zinc finger protein 438
chr3_+_173954940	1.524	NM_018098	ECT2	epithelial cell transforming sequence 2 oncogene
chr4_+_86918882	1.498		ARHGAP24	Rho GTPase activating protein 24
chr13_-_40454188	1.497		ELF1	E74-like factor 1 (ets domain transcription factor)
chr5_-_88155360	1.454	NM_001193348 NM_001193349	MEF2C	myocyte enhancer factor 2C
chr10_-_98315090	1.346		TM9SF3	transmembrane 9 superfamily member 3
chr19_-_46504831	1.338
chr3_-_152585226	1.330	NM_022788	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr17_+_19917420	1.280		SPECC1	sperm antigen with calponin homology and coiled-coil domains 1
chr3_+_99733432	1.280	NM_005290	GPR15	G protein-coupled receptor 15
chr19_-_56612653	1.275	NM_001171156 NM_001171157 NM_001171158 NM_001171159 NM_001171160 NM_001171161 NM_033130	SIGLEC10	sialic acid binding Ig-like lectin 10
chr9_+_263025	1.273	NM_001190458 NM_001193536	DOCK8	dedicator of cytokinesis 8
chr1_+_165565006	1.216		POU2F1	POU class 2 homeobox 1
chr10_+_35466715	1.214	NM_183011 NM_183012	CREM	cAMP responsive element modulator
chr13_+_110637173	1.168	NM_001113513	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr11_+_59920062	1.161	NM_001079692 NM_032597	MS4A14	membrane-spanning 4-domains, subfamily A, member 14
chr3_-_184756101	1.158	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chr12_+_53178834	1.149	NM_001184976	NCKAP1L	NCK-associated protein 1-like
chr10_+_97505398	1.136	NM_001164178 NM_001164181 NM_001164179 NM_001164182 NM_001164183 NM_001776	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1
chr7_+_149895390	1.134	NM_018326	GIMAP4	GTPase, IMAP family member 4
chr7_-_149960218	1.132		GIMAP6	GTPase, IMAP family member 6
chr21_-_14840506	1.112	NM_022136	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr12_-_9777126	1.104	NM_172004	CLECL1	C-type lectin-like 1
chr20_-_33783409	1.069		RBM39	RNA binding motif protein 39
chr9_-_21375258	1.068	NM_000605	IFNA2	interferon, alpha 2
chr12_-_10173947	1.063	NM_022570 NM_197947 NM_197948 NM_197949 NM_197950 NM_197954	CLEC7A	C-type lectin domain family 7, member A
chr4_-_77176163	1.062	NM_005409	CXCL11	chemokine (C-X-C motif) ligand 11
chr5_+_67622242	1.054	NM_181504	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_+_12795111	1.048	NM_016562	TLR7	toll-like receptor 7
chr14_+_69306019	1.041		SRSF5	serine/arginine-rich splicing factor 5
chr13_+_110653407	1.028		ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr1_+_196874759	1.011	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr2_-_207291364	0.986	NM_001093730	DYTN	dystrotelin
chr3_-_15357878	0.978	NM_001018009	SH3BP5	SH3-domain binding protein 5 (BTK-associated)
chr8_-_81155564	0.972	NM_001025252	TPD52	tumor protein D52
chr9_+_107464558	0.965	NM_005421	TAL2	T-cell acute lymphocytic leukemia 2
chr8_-_95298706	0.963	NM_001144663	CDH17	cadherin 17, LI cadherin (liver-intestine)
chr6_-_33149244	0.963	NM_033554	HLA-DPA1	major histocompatibility complex, class II, DP alpha 1
chr9_-_133602745	0.960	NM_005312	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1
chr11_-_5212168	0.956	NM_000519	HBD	hemoglobin, delta
chr2_+_102294393	0.951	NM_016232	IL18R1 IL1RL1	interleukin 18 receptor 1 interleukin 1 receptor-like 1
chr5_+_148711419	0.929		GRPEL2	GrpE-like 2, mitochondrial (E. coli)
chr11_+_59902598	0.928		MS4A7	membrane-spanning 4-domains, subfamily A, member 7
chr12_+_63510481	0.914
chr7_+_37689903	0.895
chr1_+_84382575	0.888		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr5_+_57823017	0.887	NM_152687	GAPT	GRB2-binding adaptor protein, transmembrane
chr12_+_12829807	0.886	NM_030817	APOLD1	apolipoprotein L domain containing 1
chr15_+_64481270	0.883		MAP2K1	mitogen-activated protein kinase kinase 1
chr8_-_27997306	0.881	NM_001010906	C8orf80	chromosome 8 open reading frame 80
chr1_+_196874867	0.865		PTPRC	protein tyrosine phosphatase, receptor type, C
chr12_-_14929991	0.862	NM_000900 NM_001190839	MGP	matrix Gla protein
chr1_+_196874839	0.854		PTPRC	protein tyrosine phosphatase, receptor type, C
chr13_+_47948586	0.851		RB1	retinoblastoma 1
chr1_-_20318578	0.839	NM_012400	PLA2G2D	phospholipase A2, group IID
chr14_+_87541220	0.838	NM_003608	GPR65	G protein-coupled receptor 65
chr4_-_110942576	0.829		CFI	complement factor I
chr5_-_156468614	0.822	NM_032782	HAVCR2	hepatitis A virus cellular receptor 2
chr17_+_29621352	0.821	NM_006273	CCL7	chemokine (C-C motif) ligand 7
chr22_-_40666168	0.821	NM_001110215	CENPM	centromere protein M
chr1_+_246578699	0.819	NM_001001918	OR14C36	olfactory receptor, family 14, subfamily C, member 36
chrX_+_114734074	0.818	NM_001136025 NM_001172335	PLS3	plastin 3
chr6_+_167445284	0.817	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr4_-_38710376	0.816	NM_024943	TMEM156	transmembrane protein 156
chr6_-_33085329	0.814	NM_002119	HLA-DOA	major histocompatibility complex, class II, DO alpha
chr3_+_123256902	0.806	NM_175862	CD86	CD86 molecule
chr5_-_156468571	0.802		HAVCR2	hepatitis A virus cellular receptor 2
chr14_-_105796665	0.797		IGHV4-31 IGHV3-23 IGHA1 IGHG1 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 3-23 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr7_-_107930170	0.780		PNPLA8	patatin-like phospholipase domain containing 8
chr3_+_123779122	0.772	NM_001113523	PARP15	poly (ADP-ribose) polymerase family, member 15
chr16_+_28993770	0.771		RRN3P2	RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2
chr11_-_104332631	0.769	NM_033306	CASP4	caspase 4, apoptosis-related cysteine peptidase
chr8_+_24297742	0.769	NM_001145271 NM_001145272 NM_014479	ADAMDEC1	ADAM-like, decysin 1
chr12_-_48902692	0.768	NM_001113547	LIMA1	LIM domain and actin binding 1
chr6_+_28032997	0.766	NM_012367	OR2B6	olfactory receptor, family 2, subfamily B, member 6
chr10_+_89257569	0.765	NM_001178118	MINPP1	multiple inositol-polyphosphate phosphatase 1
chr2_+_201833467	0.762	NM_033356	CASP8	caspase 8, apoptosis-related cysteine peptidase
chr7_-_143213296	0.749		FAM115A	family with sequence similarity 115, member A
chr5_+_61910318	0.742	NM_181506	LRRC70	leucine rich repeat containing 70
chr2_-_136590210	0.741	NM_001008540	CXCR4	chemokine (C-X-C motif) receptor 4
chr5_-_75044001	0.741	NM_152408	POC5	POC5 centriolar protein homolog (Chlamydomonas)
chr10_+_70517863	0.741		SRGN	serglycin
chr6_-_159386007	0.740	NM_054114 NM_138810 NM_152133	TAGAP	T-cell activation RhoGTPase activating protein
chr19_-_53450953	0.737	NM_001184902 NM_001184904	CARD8	caspase recruitment domain family, member 8
chr2_+_201755865	0.729	NM_001230 NM_032974 NM_032977	CASP10	caspase 10, apoptosis-related cysteine peptidase
chr17_+_63367052	0.726		BPTF	bromodomain PHD finger transcription factor
chr8_-_102005697	0.724		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr14_-_19867372	0.716	NM_182852 NM_182851	CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr13_-_48873735	0.715	NM_030925	CAB39L	calcium binding protein 39-like
chr4_-_47709717	0.714	NM_000087	CNGA1	cyclic nucleotide gated channel alpha 1
chr5_-_78318112	0.713	NM_000046	ARSB	arylsulfatase B
chr1_-_89437098	0.712	NM_052941	GBP4	guanylate binding protein 4
chr1_+_178232379	0.706		CEP350	centrosomal protein 350kDa
chr22_-_34886727	0.703	NM_145640	APOL3	apolipoprotein L, 3
chr2_+_228064531	0.701		AGFG1	ArfGAP with FG repeats 1
chr7_+_106292932	0.697		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr13_-_32678142	0.691	NM_052851	STARD13	StAR-related lipid transfer (START) domain containing 13
chr1_-_204455269	0.688	NM_001007544	C1orf186	chromosome 1 open reading frame 186
chr1_+_157246305	0.687	NM_005531	IFI16	interferon, gamma-inducible protein 16
chr19_-_1601246	0.674	NM_001136139	TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr11_-_104411065	0.671	NM_001223 NM_033292 NM_033293 NM_033294 NM_033295	CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr4_-_110942783	0.668	NM_000204	CFI	complement factor I
chr9_+_21430439	0.662	NM_024013	IFNA1	interferon, alpha 1
chr17_-_26672757	0.661	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr12_+_15590811	0.658		PTPRO	protein tyrosine phosphatase, receptor type, O
chr2_-_44440358	0.658	NM_001042385 NM_001042386	PREPL	prolyl endopeptidase-like
chr5_-_150501393	0.657	NM_001193544	ANXA6	annexin A6
chr5_+_179065282	0.653		CANX	calnexin
chr8_-_110411283	0.650	NM_001128211	NUDCD1	NudC domain containing 1
chr10_+_70517823	0.649	NM_002727	SRGN	serglycin
chr3_+_39346200	0.642	NM_005201	CCR8	chemokine (C-C motif) receptor 8
chr2_-_97775300	0.641		TMEM131	transmembrane protein 131
chr12_+_9713472	0.638	NM_001197318 NM_013269 NM_001004419 NM_001197317 NM_001197319	CLEC2D	C-type lectin domain family 2, member D
chr20_-_51633042	0.638	NM_006526	ZNF217	zinc finger protein 217
chr22_+_20880112	0.637
chr16_-_45562840	0.626		DNAJA2	DnaJ (Hsp40) homolog, subfamily A, member 2
chr22_+_20880159	0.624		IGLV6-57	immunoglobulin lambda variable 6-57
chr1_+_185064654	0.624	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr3_+_32968069	0.621	NM_005508	CCR4	chemokine (C-C motif) receptor 4
chr14_+_64947592	0.618	NM_178155 NM_178156	FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr4_+_74825138	0.613	NM_000584	IL8	interleukin 8
chr10_+_127419021	0.612		C10orf137	chromosome 10 open reading frame 137
chr14_-_105549177	0.612		IGHV4-31 IGHD IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr18_-_62422195	0.608	NM_021153	CDH19	cadherin 19, type 2
chr14_-_105804211	0.608		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_134800533	0.602		LOC154092	hypothetical LOC154092
chr11_+_59027624	0.600	NM_001004706	OR4D11	olfactory receptor, family 4, subfamily D, member 11
chr9_+_104797413	0.599	NM_001340	CYLC2	cylicin, basic protein of sperm head cytoskeleton 2
chr12_+_10351683	0.599	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr2_-_45648608	0.593		SRBD1	S1 RNA binding domain 1
chr2_-_232034638	0.581		NCL	nucleolin
chr8_+_42671718	0.578	NM_000749	CHRNB3	cholinergic receptor, nicotinic, beta 3
chr8_+_104900591	0.576	NM_014677	RIMS2	regulating synaptic membrane exocytosis 2
chr4_+_86918870	0.573	NM_001042669	ARHGAP24	Rho GTPase activating protein 24
chr3_-_52688768	0.571	NM_018165 NM_181042	PBRM1	polybromo 1
chr12_+_25096755	0.571		LRMP	lymphoid-restricted membrane protein
chr11_-_104421240	0.569	NM_001017534 NM_052889	CARD16 CASP1	caspase recruitment domain family, member 16 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr19_-_44518516	0.567	NM_004877	GMFG	glia maturation factor, gamma
chr2_+_183290912	0.566		DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10
chr4_-_17415918	0.564		DCAF16	DDB1 and CUL4 associated factor 16
chr9_-_21229975	0.560	NM_002172	IFNA14	interferon, alpha 14
chr13_-_45654292	0.560		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_14429499	0.554		ATF7IP	activating transcription factor 7 interacting protein
chr12_-_10953427	0.553	NM_023920	TAS2R13	taste receptor, type 2, member 13
chr12_+_15590552	0.553	NM_030668 NM_030669 NM_030670 NM_030671	PTPRO	protein tyrosine phosphatase, receptor type, O
chr19_-_14750347	0.553	NM_013447 NM_152916 NM_152917 NM_152918 NM_152919 NM_152920 NM_152921	EMR2	egf-like module containing, mucin-like, hormone receptor-like 2
chr1_+_67404756	0.549	NM_144701	IL23R	interleukin 23 receptor
chr8_+_11388918	0.543	NM_001715	BLK	B lymphoid tyrosine kinase
chr11_-_58032153	0.542	NM_001005218	OR5B21	olfactory receptor, family 5, subfamily B, member 21
chr1_+_51340487	0.535	NM_001136508	C1orf185	chromosome 1 open reading frame 185
chr19_-_16111695	0.533
chr17_+_65009986	0.532		MAP2K6	mitogen-activated protein kinase kinase 6
chr11_-_117600918	0.532	NM_001098526	AMICA1	adhesion molecule, interacts with CXADR antigen 1
chr1_-_111544820	0.526		DENND2D	DENN/MADD domain containing 2D
chr12_+_48443588	0.525		TMBIM6	transmembrane BAX inhibitor motif containing 6
chr1_+_84382529	0.524	NM_182948	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr7_-_131983986	0.521	NM_181775	PLXNA4	plexin A4
chr1_-_157551072	0.521	NM_001004467	OR10J3	olfactory receptor, family 10, subfamily J, member 3
chr7_-_33047042	0.517	NM_001166118 NM_016489	NT5C3	5'-nucleotidase, cytosolic III
chr4_-_83566045	0.510
chr12_-_16652202	0.509	NM_001001395	LMO3	LIM domain only 3 (rhombotin-like 2)
chrX_+_48427137	0.508		WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chrX_-_138742050	0.507	NM_001010986 NM_173694	ATP11C	ATPase, class VI, type 11C
chr7_+_90177082	0.507		CDK14	cyclin-dependent kinase 14
chr8_+_24207524	0.507	NM_014265 NM_021777	ADAM28	ADAM metallopeptidase domain 28
chr10_+_35524060	0.501	NM_182717 NM_182718 NM_182719 NM_182720	CREM	cAMP responsive element modulator
chr8_-_120720200	0.499	NM_001040092 NM_001130863 NM_006209	ENPP2	ectonucleotide pyrophosphatase/phosphodiesterase 2
chr22_-_16080265	0.498		CECR1	cat eye syndrome chromosome region, candidate 1
chr8_-_17599438	0.497	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chr3_+_142587973	0.496
chr11_+_67107852	0.493		GSTP1	glutathione S-transferase pi 1
chr12_+_9871343	0.489	NM_016523	KLRF1	killer cell lectin-like receptor subfamily F, member 1
chr17_-_39094787	0.486	NM_001040002	MEOX1	mesenchyme homeobox 1
chr6_+_26476384	0.485	NM_001197246	BTN3A2	butyrophilin, subfamily 3, member A2
chr2_+_134728299	0.483	NM_002410	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr16_-_29797172	0.478		SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr18_+_70471906	0.476	NM_001146189 NM_001146190 NM_017757	ZNF407	zinc finger protein 407
chr19_+_42409205	0.476	NM_152604	ZNF383	zinc finger protein 383

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.82	4.13e-11	GO:0002376	immune system process
2.09	5.66e-11	GO:0006955	immune response
2.25	5.94e-07	GO:0051707	response to other organism
1.83	1.01e-06	GO:0006952	defense response
2.06	3.11e-06	GO:0009607	response to biotic stimulus
2.89	1.84e-05	GO:0009615	response to virus
2.04	4.93e-05	GO:0050776	regulation of immune response
1.81	4.95e-05	GO:0002682	regulation of immune system process
1.20	2.37e-04	GO:0050896	response to stimulus
1.99	2.07e-03	GO:0045087	innate immune response
1.60	2.51e-03	GO:0051704	multi-organism process
2.82	1.12e-02	GO:0070663	regulation of leukocyte proliferation
1.98	1.14e-02	GO:0031347	regulation of defense response
1.31	1.23e-02	GO:0006950	response to stress
1.81	1.72e-02	GO:0002684	positive regulation of immune system process
2.02	1.76e-02	GO:0050778	positive regulation of immune response
1.78	1.80e-02	GO:0007606	sensory perception of chemical stimulus
2.80	1.97e-02	GO:0050670	regulation of lymphocyte proliferation
2.77	2.33e-02	GO:0032944	regulation of mononuclear cell proliferation
2.15	2.34e-02	GO:0002253	activation of immune response
2.41	3.99e-02	GO:0002252	immune effector process
1.79	4.02e-02	GO:0007608	sensory perception of smell

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.45	7.22e-05	GO:0004872	receptor activity
1.34	2.34e-03	GO:0004871	signal transducer activity
1.34	2.34e-03	GO:0060089	molecular transducer activity
1.55	4.64e-03	GO:0004930	G-protein coupled receptor activity
1.84	4.69e-03	GO:0004984	olfactory receptor activity
1.41	1.39e-02	GO:0004888	transmembrane receptor activity