Motif ID: ZIC1..3.p2

Z-value: 2.511


Transcription factors associated with ZIC1..3.p2:

Gene SymbolEntrez IDGene Name
ZIC1 7545 Zic family member 1 (odd-paired homolog, Drosophila)
ZIC2 7546 Zic family member 2 (odd-paired homolog, Drosophila)
ZIC3 7547 Zic family member 3 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZIC1chr3_+_1486105160.945.2e-08Click!
ZIC3chrX_+_1364759790.721.7e-03Click!
ZIC2chr13_+_99432258-0.126.5e-01Click!


Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_73756668 8.134 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr16_+_85169615 5.428 NM_005250
FOXL1
forkhead box L1
chr3_+_64645819 5.260 LOC100507098
hypothetical LOC100507098
chr21_-_26867138 4.886 NM_052954
CYYR1
cysteine/tyrosine-rich 1
chr10_-_90702490 4.536 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr7_-_27191287 3.656 NM_005523
HOXA11
homeobox A11
chr12_+_52653176 3.528 NM_014212
HOXC11
homeobox C11
chr5_-_168660293 3.381 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr10_+_75343352 3.291 PLAU
plasminogen activator, urokinase
chr22_-_36153449 3.037 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr20_+_19903778 2.924 RIN2
Ras and Rab interactor 2
chr11_-_126375864 2.922 KIRREL3
kin of IRRE like 3 (Drosophila)
chr4_+_72271218 2.902 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr14_+_85066265 2.869 FLRT2
fibronectin leucine rich transmembrane protein 2
chr19_-_13910167 2.780 NM_024825
PODNL1
podocan-like 1
chr1_+_199519202 2.755 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr21_-_27139143 2.669 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr21_-_27139563 2.624 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr9_+_108665168 2.623 NM_021224
ZNF462
zinc finger protein 462
chr22_-_26527469 2.585 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr17_-_15185623 2.568 NM_031898
TEKT3
tektin 3
chr11_-_126375895 2.547 NM_001161707
NM_032531
KIRREL3

kin of IRRE like 3 (Drosophila)

chr5_+_131437383 2.535 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr9_-_72673753 2.513 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr11_+_131285747 2.470 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr12_-_50871953 2.418 NM_001081492
NM_182507
KRT80

keratin 80

chrX_+_90576252 2.395 NM_080832
PABPC5
poly(A) binding protein, cytoplasmic 5
chr10_+_52421120 2.377 PRKG1
protein kinase, cGMP-dependent, type I
chr16_+_85158357 2.364 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr5_+_175725050 2.339 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr11_-_11986704 2.305 NM_001018057
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr7_-_27180398 2.287 NM_018951
HOXA10
homeobox A10
chr12_+_5411534 2.277 NM_001102654
NTF3
neurotrophin 3
chr7_+_27191534 2.216 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr17_-_72045218 2.207 NM_134268
CYGB
cytoglobin
chr2_-_133144094 2.201 LYPD1
LY6/PLAUR domain containing 1
chrX_-_107866262 2.198 NM_003604
IRS4
insulin receptor substrate 4
chr17_-_28644118 2.136 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr19_-_56147971 2.120 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr6_+_101948102 2.092


chr3_+_155321826 2.085 NM_015595
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr11_-_111287657 2.076 NM_001885
CRYAB
crystallin, alpha B
chr3_+_189353502 2.049 LPP
LIM domain containing preferred translocation partner in lipoma
chrX_-_43717864 2.044 NM_000266
NDP
Norrie disease (pseudoglioma)
chr11_+_111288669 2.037 NM_001541
HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr9_+_112470871 2.032 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr11_+_111288686 1.999 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr8_+_31616809 1.991 NM_013962
NRG1
neuregulin 1
chr9_+_134027154 1.958 NM_032536
NTNG2
netrin G2
chr5_-_58607673 1.957 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_+_101887562 1.954 NM_001142529
NM_001142530
BHLHB9

basic helix-loop-helix domain containing, class B, 9

chr5_-_44424423 1.950 NM_004465
FGF10
fibroblast growth factor 10
chr7_-_112513379 1.939 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr16_+_66244314 1.919 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr9_-_112840064 1.915 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr19_-_60573552 1.902 NM_000641
IL11
interleukin 11
chr11_-_27697768 1.873 NM_001143807
BDNF
brain-derived neurotrophic factor
chr1_+_168899936 1.853 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr7_+_114350144 1.835 MDFIC
MyoD family inhibitor domain containing
chr9_-_121171400 1.833 NM_014618
DBC1
deleted in bladder cancer 1
chr12_-_42231990 1.822 NM_025003
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr1_+_201363458 1.817 NM_000674
NM_001048230
ADORA1

adenosine A1 receptor

chr5_-_174803768 1.805 NM_000794
DRD1
dopamine receptor D1
chr7_+_27190688 1.771


chr8_-_17599438 1.750 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chrX_+_101792949 1.742 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr8_+_70541631 1.741 SULF1
sulfatase 1
chr15_+_37660568 1.741 NM_003246
THBS1
thrombospondin 1
chr3_-_166397142 1.719 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chrX_-_30237403 1.717 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr3_-_55490401 1.696 WNT5A
wingless-type MMTV integration site family, member 5A
chr6_-_112001590 1.693 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr5_-_121440704 1.673 NM_001178102
LOX
lysyl oxidase
chr12_-_80676562 1.660 PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr6_-_169392771 1.654


chrX_-_48818585 1.643 NM_007213
PRAF2
PRA1 domain family, member 2
chr19_-_45888259 1.640 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr11_-_122571046 1.614 CLMP
CXADR-like membrane protein
chr2_+_219991342 1.601 NM_001927
DES
desmin
chr7_-_27120015 1.598 HOXA3
homeobox A3
chr9_+_134026836 1.588 NTNG2
netrin G2
chr3_-_113841200 1.584 CCDC80
coiled-coil domain containing 80
chr8_-_22044463 1.580 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr11_-_132318741 1.578 OPCML
opioid binding protein/cell adhesion molecule-like
chr11_-_110917632 1.559


chr9_-_103289154 1.550 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr20_-_3713509 1.544 CENPB
centromere protein B, 80kDa
chr14_+_100362236 1.541 MEG3
maternally expressed 3 (non-protein coding)
chr12_+_52733927 1.539 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr11_-_11987115 1.539 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr1_-_21478571 1.534 NM_001113347
ECE1
endothelin converting enzyme 1
chr4_+_159311353 1.530 LOC285505
hypothetical protein LOC285505
chr18_+_17076166 1.526 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr8_-_145097031 1.511 NM_201380
PLEC
plectin
chr10_+_8137356 1.508 GATA3
GATA binding protein 3
chr16_+_54070302 1.495 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr15_+_81906983 1.487 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr19_-_53912025 1.476 NM_182574
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr14_+_100362204 1.467 MEG3
maternally expressed 3 (non-protein coding)
chr3_+_160964574 1.459 SCHIP1
schwannomin interacting protein 1
chr12_+_77782925 1.457 SYT1
synaptotagmin I
chr1_+_13782838 1.456 NM_006474
NM_198389
PDPN

podoplanin

chr10_+_68355797 1.443 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr3_+_148610516 1.437 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr5_-_83715947 1.433 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr17_+_7549138 1.430 NM_001406
EFNB3
ephrin-B3
chr10_+_106018915 1.424 GSTO2
glutathione S-transferase omega 2
chr20_-_22978141 1.417 NM_000361
THBD
thrombomodulin
chr9_+_111850698 1.405 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr16_-_31390926 1.395


chr4_+_166519392 1.387 NM_001873
CPE
carboxypeptidase E
chrX_-_114374860 1.381 NM_020871
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr9_+_4480193 1.380 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr2_+_217206450 1.371 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr18_+_54013575 1.362 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr3_-_21767819 1.361 NM_024697
ZNF385D
zinc finger protein 385D
chr7_-_27190882 1.341 HOXA11
homeobox A11
chr15_-_98959898 1.337 NM_001040616
LINS
lines homolog (Drosophila)
chr4_+_156808261 1.325 NM_001130684
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr20_+_61798512 1.315 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr20_+_61798446 1.310 NM_003823
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr8_-_93144366 1.306 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_234372454 1.303 NM_003272
GPR137B
G protein-coupled receptor 137B
chr12_+_77782719 1.300 SYT1
synaptotagmin I
chr1_+_201364050 1.283 ADORA1
adenosine A1 receptor
chr2_+_217206327 1.275 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr9_+_78824390 1.264 NM_001013735
FOXB2
forkhead box B2
chr1_+_116181927 1.264 NHLH2
nescient helix loop helix 2
chr6_+_133604181 1.261 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr12_-_21985433 1.259 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr6_+_41714171 1.252 NM_005586
MDFI
MyoD family inhibitor
chr8_+_1909437 1.249 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr12_+_54400417 1.244 NM_002905
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr5_+_140835788 1.238 PCDHGC3
protocadherin gamma subfamily C, 3
chr16_+_31390567 1.237 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr13_+_30378311 1.235 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr6_+_26348539 1.233 NM_003540
HIST1H4F
histone cluster 1, H4f
chr1_-_212791188 1.227 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_+_119292699 1.217


chr15_-_53996597 1.216 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr22_-_49063088 1.214 PLXNB2
plexin B2
chr10_-_71575953 1.202 TYSND1
trypsin domain containing 1
chr5_+_140326473 1.201 NM_031883
PCDHAC2
protocadherin alpha subfamily C, 2
chr5_-_92982927 1.198


chr12_-_80677223 1.190 NM_003625
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr20_+_35583020 1.187 NM_005386
NM_181689
NNAT

neuronatin

chr3_+_3816079 1.187 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr12_+_6179736 1.187 NM_001769
CD9
CD9 molecule
chr12_+_77782648 1.187 SYT1
synaptotagmin I
chr11_+_19691397 1.184 NM_145117
NM_182964
NAV2

neuron navigator 2

chr22_-_42589543 1.181 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr8_-_93144039 1.179


chr2_+_220033777 1.175 NM_001173476
SPEG
SPEG complex locus
chr14_+_64077171 1.162 HSPA2
heat shock 70kDa protein 2
chr4_-_90977149 1.162 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr8_+_75899326 1.156 NM_015886
PI15
peptidase inhibitor 15
chr7_-_150576634 1.147 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr5_+_140326237 1.137 PCDHAC2
protocadherin alpha subfamily C, 2
chr11_-_35503720 1.137 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr4_+_15089931 1.135 CC2D2A
coiled-coil and C2 domain containing 2A
chrX_+_51653348 1.132 NM_001005333
NM_006986
MAGED1

melanoma antigen family D, 1

chr17_-_30838870 1.125 NM_001195790
SLFN12L
schlafen family member 12-like
chr11_-_11987198 1.121 NM_015881
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr6_+_142664490 1.120 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr11_+_122806196 1.103 LOC100128242
hypothetical LOC100128242
chr19_-_13478037 1.103 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr14_+_104218487 1.099


chr6_+_148705817 1.094 SASH1
SAM and SH3 domain containing 1
chr7_+_44110527 1.091 AEBP1
AE binding protein 1
chr12_-_131697109 1.089 NM_001195520
LOC645277
hypothetical LOC645277
chr5_+_140835727 1.087 NM_002588
NM_032402
NM_032403
PCDHGC3


protocadherin gamma subfamily C, 3


chr6_-_166321516 1.081 C6orf176
chromosome 6 open reading frame 176
chr19_-_13808101 1.078 LOC284454
hypothetical LOC284454
chr6_+_142665057 1.072 GPR126
G protein-coupled receptor 126
chr7_-_107883929 1.063 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr4_+_156807311 1.052 NM_000856
NM_001130682
NM_001130686
NM_001130687
NM_001130683
NM_001130685
GUCY1A3





guanylate cyclase 1, soluble, alpha 3





chr11_+_19328846 1.052 NM_001111018
NAV2
neuron navigator 2
chr1_+_232107170 1.049 NM_173508
SLC35F3
solute carrier family 35, member F3
chr15_-_27901828 1.046 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr8_+_76059262 1.043 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr1_+_17817397 1.041 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_+_200124412 1.038 NM_198149
SHISA4
shisa homolog 4 (Xenopus laevis)
chr8_-_132122016 1.033 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr14_+_64076916 1.031 NM_021979
HSPA2
heat shock 70kDa protein 2
chr5_-_134942346 1.030 CXCL14
chemokine (C-X-C motif) ligand 14
chr10_-_105202012 1.018 CALHM2
calcium homeostasis modulator 2
chr7_-_27102049 1.016 NM_005522
NM_153620
HOXA1

homeobox A1

chr5_+_167889123 1.016


chr6_+_17389752 1.010 NM_001143942
RBM24
RNA binding motif protein 24
chr3_+_115099007 1.009 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr1_+_110494654 1.008 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr19_+_10597167 1.007 NM_020428
SLC44A2
solute carrier family 44, member 2
chr8_+_39084206 1.006 NM_145004
ADAM32
ADAM metallopeptidase domain 32
chr8_-_11096257 1.005 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr3_-_113841448 1.004 CCDC80
coiled-coil domain containing 80
chr3_+_50281582 1.003 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr6_+_19946591 0.999


chr4_-_159311959 0.992 FAM198B
family with sequence similarity 198, member B
chr2_-_192767844 0.991 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr15_+_98960277 0.985 NM_024708
NM_198243
ASB7

ankyrin repeat and SOCS box containing 7


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.51 3.44e-08 GO:0009653 anatomical structure morphogenesis
1.32 5.70e-08 GO:0048856 anatomical structure development
1.27 3.94e-07 GO:0032502 developmental process
1.33 4.56e-07 GO:0048731 system development
1.17 4.90e-07 GO:0050794 regulation of cellular process
1.45 6.25e-07 GO:0023051 regulation of signaling
1.39 9.45e-07 GO:0030154 cell differentiation
1.38 1.08e-06 GO:0048869 cellular developmental process
1.27 7.05e-06 GO:0007275 multicellular organismal development
1.10 9.51e-06 GO:0009987 cellular process
1.59 1.19e-05 GO:0009888 tissue development
1.44 1.35e-05 GO:0007399 nervous system development
1.35 1.63e-05 GO:0048523 negative regulation of cellular process
1.15 2.57e-05 GO:0050789 regulation of biological process
1.43 3.84e-05 GO:0009966 regulation of signal transduction
1.14 6.16e-05 GO:0065007 biological regulation
1.24 9.52e-05 GO:0023052 signaling
1.30 2.27e-04 GO:0048519 negative regulation of biological process
1.60 2.29e-04 GO:0009790 embryo development
1.88 2.64e-04 GO:0007389 pattern specification process
1.47 2.97e-04 GO:0010646 regulation of cell communication
1.84 3.06e-04 GO:0048598 embryonic morphogenesis
2.33 4.40e-04 GO:0043062 extracellular structure organization
1.75 4.44e-04 GO:0010648 negative regulation of cell communication
1.81 6.52e-04 GO:0043009 chordate embryonic development
1.74 7.97e-04 GO:0023057 negative regulation of signaling
1.76 9.90e-04 GO:0009968 negative regulation of signal transduction
1.79 1.06e-03 GO:0009792 embryo development ending in birth or egg hatching
1.47 1.22e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.49 1.33e-03 GO:0022008 neurogenesis
1.50 1.36e-03 GO:0048699 generation of neurons
1.85 1.83e-03 GO:0001501 skeletal system development
1.53 1.99e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.53 2.08e-03 GO:0035107 appendage morphogenesis
2.53 2.08e-03 GO:0035108 limb morphogenesis
1.52 2.15e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.99 2.19e-03 GO:0048568 embryonic organ development
1.85 2.36e-03 GO:0022603 regulation of anatomical structure morphogenesis
2.10 2.38e-03 GO:0048732 gland development
1.52 3.32e-03 GO:2000026 regulation of multicellular organismal development
1.22 3.61e-03 GO:0016043 cellular component organization
1.58 4.22e-03 GO:0009887 organ morphogenesis
1.48 4.83e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.25 4.87e-03 GO:0071842 cellular component organization at cellular level
2.43 5.28e-03 GO:0048736 appendage development
2.43 5.28e-03 GO:0060173 limb development
1.31 5.66e-03 GO:0048583 regulation of response to stimulus
1.55 6.78e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.93 6.85e-03 GO:0003002 regionalization
1.80 7.28e-03 GO:0060284 regulation of cell development
1.47 7.57e-03 GO:0009891 positive regulation of biosynthetic process
1.81 9.53e-03 GO:0048729 tissue morphogenesis
1.44 1.01e-02 GO:0050793 regulation of developmental process
1.44 1.08e-02 GO:0048468 cell development
1.51 1.26e-02 GO:0030182 neuron differentiation
1.63 1.29e-02 GO:0072358 cardiovascular system development
1.63 1.29e-02 GO:0072359 circulatory system development
2.24 1.31e-02 GO:0048705 skeletal system morphogenesis
1.61 1.32e-02 GO:0048585 negative regulation of response to stimulus
2.61 1.34e-02 GO:0048706 embryonic skeletal system development
1.20 1.50e-02 GO:0071840 cellular component organization or biogenesis
1.29 1.66e-02 GO:0048513 organ development
1.48 1.78e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
3.01 1.82e-02 GO:0050808 synapse organization
1.23 1.95e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.50 2.49e-02 GO:0010628 positive regulation of gene expression
1.78 2.59e-02 GO:0001944 vasculature development
1.59 3.11e-02 GO:0019226 transmission of nerve impulse
1.59 3.11e-02 GO:0035637 multicellular organismal signaling
1.41 3.12e-02 GO:0042127 regulation of cell proliferation
1.57 3.22e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.23 3.24e-02 GO:0048518 positive regulation of biological process
1.24 3.36e-02 GO:0048522 positive regulation of cellular process
1.51 4.18e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.41 4.41e-02 GO:0030326 embryonic limb morphogenesis
2.41 4.41e-02 GO:0035113 embryonic appendage morphogenesis
1.61 4.45e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
2.03 4.46e-02 GO:0009952 anterior/posterior pattern formation
2.05 4.95e-02 GO:0048562 embryonic organ morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.75 1.69e-07 GO:0030054 cell junction
1.33 6.55e-06 GO:0044459 plasma membrane part
1.79 3.42e-05 GO:0045202 synapse
2.32 2.14e-04 GO:0034703 cation channel complex
2.10 2.95e-03 GO:0005912 adherens junction
1.90 3.87e-03 GO:0034702 ion channel complex
6.41 5.68e-03 GO:0043256 laminin complex
2.33 6.18e-03 GO:0005925 focal adhesion
2.00 6.35e-03 GO:0070161 anchoring junction
1.72 8.40e-03 GO:0044456 synapse part
1.09 1.27e-02 GO:0005737 cytoplasm
1.77 1.38e-02 GO:0005667 transcription factor complex
1.06 1.42e-02 GO:0005622 intracellular
2.22 1.67e-02 GO:0005924 cell-substrate adherens junction
2.14 3.49e-02 GO:0030055 cell-substrate junction
1.91 3.90e-02 GO:0030136 clathrin-coated vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.21 1.42e-03 GO:0022843 voltage-gated cation channel activity
1.80 2.10e-03 GO:0008134 transcription factor binding
1.40 3.80e-03 GO:0030528 transcription regulator activity
1.11 8.35e-03 GO:0005515 protein binding
1.94 9.12e-03 GO:0005244 voltage-gated ion channel activity
1.94 9.12e-03 GO:0022832 voltage-gated channel activity
1.72 3.45e-02 GO:0005261 cation channel activity