Motif ID: AAUCUCA

Z-value: 0.347


Mature miRNA associated with seed AAUCUCA:

NamemiRBase Accession
hsa-miR-216a MIMAT0000273



Activity profile for motif AAUCUCA.

activity profile for motif AAUCUCA


Sorted Z-values histogram for motif AAUCUCA

Sorted Z-values for motif AAUCUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_53342320 0.337 NM_002126
HLF
hepatic leukemia factor
chr3_+_142375738 0.275 NM_001172312
PLS1
plastin 1
chr3_+_142342265 0.274 NM_002670
PLS1
plastin 1
chr3_+_142315205 0.270 NM_001145319
PLS1
plastin 1
chr2_+_178257371 0.178 NM_003659
AGPS
alkylglycerone phosphate synthase
chr1_-_207205996 0.174 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr7_-_139876718 0.169 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr13_-_76055872 0.142 NM_014832
TBC1D4
TBC1 domain family, member 4
chr5_+_112312392 0.142 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr1_-_53793743 0.139 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chrX_-_20284708 0.129 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr2_+_101436491 0.127 NM_002518
NPAS2
neuronal PAS domain protein 2
chr4_-_90759446 0.125 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_90758126 0.119 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr5_-_148442606 0.118 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr18_-_28622624 0.111 NM_001941
NM_024423
DSC3

desmocollin 3

chr10_-_116444374 0.111 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr10_-_116286661 0.103 NM_006720
ABLIM1
actin binding LIM protein 1
chr2_-_242212244 0.102 NM_001243900
NM_203346
HDLBP

high density lipoprotein binding protein

chr10_-_116418056 0.101 NM_002313
ABLIM1
actin binding LIM protein 1
chr2_+_113885137 0.100 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr3_-_142166782 0.094 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr1_-_151882360 0.086 NM_053055
THEM4
thioesterase superfamily member 4
chr16_-_19729417 0.085 NM_001012991
C16orf88
chromosome 16 open reading frame 88
chr12_-_57030083 0.083 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr1_-_160990971 0.082 NM_016946
F11R
F11 receptor
chr2_+_135676387 0.079 NM_001241
NM_058241
CCNT2

cyclin T2

chr16_+_69599868 0.079 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr2_+_73441344 0.076 NM_006062
SMYD5
SMYD family member 5
chr3_-_48700317 0.076 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr2_-_128100673 0.075 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr7_-_139477437 0.074 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr16_+_8806825 0.071 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr14_-_104313730 0.071 NM_015316
PPP1R13B
protein phosphatase 1, regulatory subunit 13B
chr6_+_7590405 0.070 NM_152551
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr14_+_32798478 0.070 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr1_+_167298280 0.069 NM_001198783
POU2F1
POU class 2 homeobox 1
chr11_+_111944967 0.069 NM_001082969
NM_001082970
NM_018195
C11orf57


chromosome 11 open reading frame 57


chr2_+_113875469 0.068 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr15_-_33360084 0.068 NM_001103184
FMN1
formin 1
chr4_+_3076236 0.067 NM_002111
HTT
huntingtin
chr16_-_57520326 0.064 NM_018110
DOK4
docking protein 4
chr17_-_73975507 0.063 NM_001185039
NM_004035
NM_007292
ACOX1


acyl-CoA oxidase 1, palmitoyl


chr22_-_46933066 0.062 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr6_+_10555948 0.062 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr16_+_8814567 0.061 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr2_-_203776948 0.061 NM_018256
WDR12
WD repeat domain 12
chr3_-_64673330 0.061 NM_182920
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr2_-_214015053 0.061 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr6_+_42788793 0.060 NM_015349
KIAA0240
KIAA0240
chr10_+_97803064 0.059 NM_001134375
NM_001134376
NM_019084
CCNJ


cyclin J


chr21_-_43373938 0.057 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr4_+_175204827 0.057 NM_001040157
CEP44
centrosomal protein 44kDa
chr13_-_21476895 0.054 NM_022459
XPO4
exportin 4
chr2_+_111878450 0.053 NM_001204106
NM_001204107
NM_001204108
NM_001204109
NM_001204110
NM_001204111
NM_001204112
NM_001204113
NM_006538
NM_138621
NM_138622
NM_138623
NM_138624
NM_138625
NM_138626
NM_138627
NM_207002
NM_207003
BCL2L11

















BCL2-like 11 (apoptosis facilitator)

















chr1_+_167189948 0.053 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr11_+_111807857 0.052 NM_001037954
DIXDC1
DIX domain containing 1
chr15_-_42840992 0.052 NM_153260
LRRC57
leucine rich repeat containing 57
chr6_+_10521564 0.051 NM_145649
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr15_+_40733302 0.050 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr2_-_172967234 0.049 NM_004405
DLX2
distal-less homeobox 2
chr11_+_92085261 0.049 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr22_-_19109912 0.049 NM_001173533
NM_001173534
NM_001184781
NM_005137
DGCR2



DiGeorge syndrome critical region gene 2



chr17_-_62340652 0.049 NM_018469
TEX2
testis expressed 2
chr2_+_234826042 0.049 NM_024080
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr14_+_71374111 0.048 NM_014982
PCNX
pecanex homolog (Drosophila)
chr9_-_36276930 0.048 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr13_-_31040035 0.048 NM_002128
HMGB1
high mobility group box 1
chr20_+_46130600 0.048 NM_001174087
NM_001174088
NM_006534
NM_181659
NCOA3



nuclear receptor coactivator 3



chr8_+_48872762 0.047 NM_005914
NM_182746
MCM4

minichromosome maintenance complex component 4

chr2_-_214016332 0.047 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr20_+_51588945 0.047 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr12_+_5019048 0.046 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr6_+_10585978 0.046 NM_145655
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr16_+_8768403 0.044 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr12_-_10251520 0.044 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr11_+_68228182 0.043 NM_001164160
NM_001164161
NM_001164162
NM_001164163
NM_001164164
NM_018312
PPP6R3





protein phosphatase 6, regulatory subunit 3





chr11_-_129062092 0.043 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr6_+_147829784 0.043 NM_001030060
SAMD5
sterile alpha motif domain containing 5
chr12_-_2986299 0.043 NM_001243088
NM_001243089
NM_021953
NM_202002
NM_202003
FOXM1




forkhead box M1




chr17_-_47755340 0.042 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chrX_+_119738542 0.042 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr18_+_13611664 0.042 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr15_-_55562483 0.041 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr16_-_12010518 0.040 NM_001130007
GSPT1
G1 to S phase transition 1
chrX_-_109561314 0.039 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr5_-_58295758 0.039 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_-_128894008 0.038 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr15_-_55563091 0.038 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr21_+_38791206 0.038 NM_130436
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr16_-_67840464 0.038 NM_020850
RANBP10
RAN binding protein 10
chr5_+_68800003 0.037 NM_001205255
OCLN
occludin
chr5_-_58882274 0.036 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_137549029 0.036 NM_004661
CDC23
cell division cycle 23 homolog (S. cerevisiae)
chr3_+_39851028 0.036 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr21_+_38792600 0.036 NM_130438
NM_001396
DYRK1A

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

chr3_-_121553907 0.036 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr15_-_55581969 0.035 NM_183235
RAB27A
RAB27A, member RAS oncogene family
chr5_-_34043234 0.035 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr3_-_195270004 0.034 NM_006241
PPP1R2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr9_+_71650478 0.034 NM_000144
NM_001161706
NM_181425
FXN


frataxin


chr12_+_11802726 0.034 NM_001987
ETV6
ets variant 6
chr15_+_48624354 0.034 NM_001948
DUT
deoxyuridine triphosphatase
chrX_+_122993536 0.033 NM_001204401
NM_001167
XIAP

X-linked inhibitor of apoptosis

chr15_+_48623616 0.033 NM_001025248
NM_001025249
DUT

deoxyuridine triphosphatase

chr15_+_91643181 0.032 NM_001167580
SV2B
synaptic vesicle glycoprotein 2B
chr7_-_115670828 0.032 NM_001018058
NM_012252
TFEC

transcription factor EC

chr17_+_57970442 0.032 NM_003161
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr18_+_13218777 0.032 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chrX_-_7895424 0.032 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chr4_-_139163222 0.032 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr4_-_113437327 0.032 NM_024019
NEUROG2
neurogenin 2
chr4_+_99916787 0.031 NM_015143
METAP1
methionyl aminopeptidase 1
chr5_+_68788118 0.030 NM_002538
OCLN
occludin
chr1_+_166808721 0.030 NM_017542
POGK
pogo transposable element with KRAB domain
chr1_-_109506016 0.030 NM_001048210
NM_015127
CLCC1

AKNAD1
chloride channel CLIC-like 1

AKNA domain containing 1
chr1_+_236686738 0.030 NM_006499
NM_201543
LGALS8

lectin, galactoside-binding, soluble, 8

chr14_+_70078309 0.030 NM_014734
KIAA0247
KIAA0247
chr10_+_43277953 0.029 NM_014753
BMS1
BMS1 homolog, ribosome assembly protein (yeast)
chr17_+_37793332 0.029 NM_001165937
NM_001165938
NM_006804
STARD3


StAR-related lipid transfer (START) domain containing 3


chr1_-_220263150 0.027 NM_006085
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr6_+_42952328 0.027 NM_006245
NM_180976
NM_180977
PPP2R5D


protein phosphatase 2, regulatory subunit B', delta


chr15_+_85291802 0.026 NM_014630
ZNF592
zinc finger protein 592
chr5_+_36608430 0.026 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_68915631 0.026 NM_000329
RPE65
retinal pigment epithelium-specific protein 65kDa
chr17_+_46018888 0.026 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr1_-_155532322 0.025 NM_018489
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr20_+_51801821 0.025 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr11_+_111848008 0.024 NM_033425
DIXDC1
DIX domain containing 1
chr9_-_36258383 0.024 NM_001190383
NM_001190384
NM_005476
GNE


glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase


chrX_-_7895764 0.024 NM_001142389
NM_001172672
PNPLA4

patatin-like phospholipase domain containing 4

chr4_-_88141614 0.024 NM_020803
KLHL8
kelch-like 8 (Drosophila)
chr16_-_10276115 0.024 NM_001134407
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr18_+_13620866 0.023 NM_004338
NM_181483
C18orf1

chromosome 18 open reading frame 1

chr1_-_211307314 0.023 NM_002238
NM_172362
KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr11_-_113746205 0.023 NM_020886
USP28
ubiquitin specific peptidase 28
chr4_-_66535652 0.023 NM_004439
NM_182472
EPHA5

EPH receptor A5

chr1_-_67896098 0.023 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chrX_-_111326003 0.023 NM_012471
TRPC5
transient receptor potential cation channel, subfamily C, member 5
chr3_+_42642105 0.022 NM_005385
NKTR
natural killer-tumor recognition sequence
chr20_-_524335 0.022 NM_001895
NM_177559
NM_177560
CSNK2A1


casein kinase 2, alpha 1 polypeptide


chr8_-_89339716 0.022 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr10_-_97321094 0.022 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr17_-_26941178 0.021 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr17_-_29641094 0.021 NM_006495
EVI2B
ecotropic viral integration site 2B
chr5_+_139493689 0.021 NM_005859
PURA
purine-rich element binding protein A
chr18_-_24442534 0.021 NM_004028
AQP4
aquaporin 4
chr16_-_12009804 0.020 NM_001130006
NM_002094
GSPT1

G1 to S phase transition 1

chr21_+_38739858 0.020 NM_101395
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr6_-_135271206 0.020 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr1_+_236681513 0.020 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr21_-_43346780 0.020 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr19_+_42788605 0.019 NM_015125
CIC
capicua homolog (Drosophila)
chr10_+_60028885 0.019 NM_018464
CISD1
CDGSH iron sulfur domain 1
chr2_+_178077421 0.018 NM_194247
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3
chr18_-_67624159 0.018 NM_006566
CD226
CD226 molecule
chr12_+_27863705 0.018 NM_001190864
NM_021821
MRPS35

mitochondrial ribosomal protein S35

chr16_-_18937722 0.018 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr6_-_94129059 0.018 NM_004440
EPHA7
EPH receptor A7
chr1_+_181452685 0.018 NM_000721
NM_001205293
NM_001205294
CACNA1E


calcium channel, voltage-dependent, R type, alpha 1E subunit


chr9_-_15510209 0.017 NM_021144
PSIP1
PC4 and SFRS1 interacting protein 1
chr15_-_34629941 0.017 NM_001042494
NM_001042496
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr5_+_68788387 0.017 NM_001205254
OCLN
occludin
chrX_-_109683457 0.017 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr4_-_146100793 0.016 NM_001102653
OTUD4
OTU domain containing 4
chr3_-_121264780 0.016 NM_199420
POLQ
polymerase (DNA directed), theta
chr11_+_119076974 0.016 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr12_+_50344523 0.016 NM_000486
AQP2
aquaporin 2 (collecting duct)
chr5_-_64064483 0.016 NM_173829
SREK1IP1
SREK1-interacting protein 1
chr17_+_48046561 0.015 NM_138281
DLX4
distal-less homeobox 4
chr12_-_31743822 0.015 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr6_-_24666818 0.015 NM_016614
TDP2
tyrosyl-DNA phosphodiesterase 2
chr4_+_155665150 0.014 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr5_-_58571916 0.014 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr10_-_97200895 0.013 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr16_-_10276610 0.013 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr3_+_45927995 0.013 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr1_-_67520028 0.013 NM_015139
SLC35D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr18_+_55019720 0.012 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr5_+_130506635 0.012 NM_181705
LYRM7
Lyrm7 homolog (mouse)
chr5_-_59783885 0.012 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_+_17354562 0.012 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr6_-_32163299 0.012 NM_022107
GPSM3
G-protein signaling modulator 3
chr3_+_39093480 0.012 NM_020839
WDR48
WD repeat domain 48
chr15_+_91643429 0.012 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr5_-_59064437 0.011 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_126226095 0.011 NM_006278
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr8_+_101162838 0.011 NM_005034
POLR2K
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr3_-_160283361 0.011 NM_002268
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr17_-_4167028 0.011 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr1_+_236687026 0.011 NM_201544
LGALS8
lectin, galactoside-binding, soluble, 8
chr8_+_67341244 0.010 NM_015169
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr5_-_58652671 0.010 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_+_104161118 0.010 NM_003452
NM_197977
ZNF189

zinc finger protein 189

chr17_+_14204326 0.010 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr18_-_24445652 0.010 NM_001650
AQP4
aquaporin 4
chr4_+_76649826 0.009 NM_003715
USO1
USO1 vesicle docking protein homolog (yeast)
chr5_-_59189620 0.009 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr21_+_35736322 0.009 NM_172201
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr5_+_36606456 0.009 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.