Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 1.812


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
AHRchr7_+_17338182-0.639.4e-03Click!
ARNT2chr15_+_80696569-0.621.0e-02Click!
ARNTchr1_-_1508492110.282.9e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_203499819 2.872 NM_173511
FAM117B
family with sequence similarity 117, member B
chr12_+_4382882 2.218 NM_001759
CCND2
cyclin D2
chr15_-_69113089 1.757 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr15_-_69113213 1.722 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr18_+_21269528 1.504 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chrX_+_37545008 1.449 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr6_-_10412606 1.418 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_-_6662681 1.346 KLHL21
kelch-like 21 (Drosophila)
chr3_+_193853930 1.222 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chrX_+_109246338 1.215 NM_032227
TMEM164
transmembrane protein 164
chr22_+_21771661 1.157 NM_015094
HIC2
hypermethylated in cancer 2
chr12_-_46662533 1.133 SLC38A1
solute carrier family 38, member 1
chr6_-_167369990 1.131 RNASET2
ribonuclease T2
chr3_+_193853937 1.121 HES1
hairy and enhancer of split 1, (Drosophila)
chr1_+_1407112 1.118 ATAD3B
ATPase family, AAA domain containing 3B
chr16_+_22825806 1.087 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr4_+_38665587 1.075 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr7_+_139044997 1.064 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr15_+_52311408 1.053 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr10_-_103879933 1.040 NM_001113407
LDB1
LIM domain binding 1
chr15_+_52311432 1.028 MAPK6
mitogen-activated protein kinase 6
chr15_+_84115979 1.028 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr6_-_167370037 1.019 NM_003730
RNASET2
ribonuclease T2
chr19_-_663155 1.003 RNF126
ring finger protein 126
chr1_+_1407158 1.001 NM_031921
ATAD3B
ATPase family, AAA domain containing 3B
chr16_+_22825481 0.967 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_-_43424324 0.960 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr15_+_41136622 0.947 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr7_-_95951268 0.945 NM_001160210
NM_014251
SLC25A13

solute carrier family 25, member 13 (citrin)

chr10_-_104178900 0.918 NM_002779
PSD
pleckstrin and Sec7 domain containing
chr7_-_91763677 0.916 CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr12_-_31479120 0.912 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr3_-_141868208 0.902 NM_001178138
NM_001178139
TFDP2

transcription factor Dp-2 (E2F dimerization partner 2)

chrX_+_109245851 0.902 NM_017698
TMEM164
transmembrane protein 164
chr14_+_101193190 0.900 NM_003836
DLK1
delta-like 1 homolog (Drosophila)
chr19_-_663158 0.886 RNF126
ring finger protein 126
chr15_+_41136178 0.880 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr1_-_113498828 0.872 NM_003051
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr20_-_33872505 0.871 NM_181468
EIF6
eukaryotic translation initiation factor 6
chr6_+_43484834 0.856 POLR1C
polymerase (RNA) I polypeptide C, 30kDa
chr9_+_4985082 0.853 JAK2
Janus kinase 2
chr19_-_663195 0.847 RNF126
ring finger protein 126
chr19_-_663219 0.841 NM_194460
RNF126
ring finger protein 126
chr15_-_75932509 0.830 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr6_+_43484776 0.827 NM_203290
POLR1C
polymerase (RNA) I polypeptide C, 30kDa
chr7_-_105925410 0.824 NM_005746
NAMPT
nicotinamide phosphoribosyltransferase
chr6_+_15245702 0.807 JARID2
jumonji, AT rich interactive domain 2
chrX_+_152954965 0.803 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr1_-_113498615 0.803 NM_001166496
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chrX_-_109561314 0.799 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr6_+_135502477 0.795 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr6_-_86352564 0.794 NM_001159674
NM_001253771
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr6_+_135502445 0.789 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr8_+_126010719 0.789 NM_003129
SQLE
squalene epoxidase
chr7_-_91763775 0.781 CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr20_-_33872289 0.775 EIF6
eukaryotic translation initiation factor 6
chr7_+_100027404 0.775 MEPCE
methylphosphate capping enzyme
chrX_-_137793394 0.766 FGF13
fibroblast growth factor 13
chrX_-_138287180 0.762 NM_001139498
NM_001139500
NM_001139501
FGF13


fibroblast growth factor 13


chr19_-_18548788 0.758 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr8_+_126010748 0.757 SQLE
squalene epoxidase
chr17_+_55162530 0.755 NM_003488
AKAP1
A kinase (PRKA) anchor protein 1
chr20_+_20348744 0.753 NM_002196
INSM1
insulinoma-associated 1
chr15_+_52311438 0.747 MAPK6
mitogen-activated protein kinase 6
chrX_-_48776282 0.741 NM_006875
PIM2
pim-2 oncogene
chr7_-_91763828 0.740 NM_000786
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr5_-_134369571 0.738 PITX1
paired-like homeodomain 1
chr8_-_30585220 0.735 GSR
glutathione reductase
chr6_-_86352635 0.731 NM_001159673
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr19_-_47291184 0.728 SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr15_+_41952572 0.719 NM_001080541
NM_001164273
MGA

MAX gene associated

chr12_-_31479038 0.712 FAM60A
family with sequence similarity 60, member A
chr8_+_126442557 0.707 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr6_+_135502521 0.704 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chrX_-_137793826 0.704 NM_004114
FGF13
fibroblast growth factor 13
chr10_+_21823266 0.701 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_-_234614848 0.696 NM_005646
TARBP1
TAR (HIV-1) RNA binding protein 1
chr7_+_139044604 0.695 NM_016019
LUC7L2
LUC7-like 2 (S. cerevisiae)
chr20_+_51588945 0.690 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr6_+_125474800 0.688 NM_001003396
NM_001003397
NM_003287
TPD52L1


tumor protein D52-like 1


chr1_+_201252579 0.686 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chrX_-_18372777 0.684 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr19_-_18548118 0.681 NM_001253389
ISYNA1
inositol-3-phosphate synthase 1
chr17_+_79679399 0.678 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr12_-_31479084 0.674 FAM60A
family with sequence similarity 60, member A
chr3_-_184870727 0.672 NM_001025266
C3orf70
chromosome 3 open reading frame 70
chr6_+_34204647 0.669 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr18_+_23806385 0.668 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr17_-_46703613 0.665 NM_024017
HOXB9
homeobox B9
chr7_+_139044696 0.662 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr16_+_31191461 0.662 FUS
fused in sarcoma
chr8_-_30585442 0.657 NM_000637
NM_001195102
NM_001195103
NM_001195104
GSR



glutathione reductase



chr1_-_54304107 0.656 NM_001168551
NM_018087
TMEM48

transmembrane protein 48

chr1_-_38273852 0.653 NM_024640
YRDC
yrdC domain containing (E. coli)
chr7_+_139044701 0.642 LUC7L2
LUC7-like 2 (S. cerevisiae)
chrX_+_19362010 0.632 NM_000284
NM_001173454
NM_001173455
NM_001173456
PDHA1



pyruvate dehydrogenase (lipoamide) alpha 1



chr1_+_1447871 0.631 NM_001170536
ATAD3A
ATPase family, AAA domain containing 3A
chrX_+_48380163 0.631 NM_006579
EBP
emopamil binding protein (sterol isomerase)
chr7_-_148581379 0.630 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr1_-_59042827 0.630 TACSTD2
tumor-associated calcium signal transducer 2
chr20_+_31350190 0.624 NM_001207055
NM_001207056
NM_006892
NM_175848
NM_175849
DNMT3B




DNA (cytosine-5-)-methyltransferase 3 beta




chr10_-_104178569 0.621 PSD
pleckstrin and Sec7 domain containing
chr1_-_38273823 0.620 YRDC
yrdC domain containing (E. coli)
chr1_-_38273846 0.620 YRDC
yrdC domain containing (E. coli)
chr12_+_104359557 0.617 NM_003211
TDG
thymine-DNA glycosylase
chr18_+_55019720 0.616 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chrX_-_109561298 0.614 AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr3_+_25831548 0.611 NM_001145391
NM_017897
OXSM

3-oxoacyl-ACP synthase, mitochondrial

chr18_+_55102777 0.610 NM_004852
ONECUT2
one cut homeobox 2
chr6_+_125475334 0.608 NM_001003395
TPD52L1
tumor protein D52-like 1
chr3_+_14444083 0.606 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chr1_-_6662898 0.603 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chr7_+_100027253 0.599 NM_019606
MEPCE
methylphosphate capping enzyme
chr1_-_38273683 0.598 YRDC
yrdC domain containing (E. coli)
chr7_+_139044669 0.597 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr1_+_1447537 0.593 ATAD3A
ATAD3B
ATPase family, AAA domain containing 3A
ATPase family, AAA domain containing 3B
chr16_+_31191462 0.591 FUS
fused in sarcoma
chr16_+_222845 0.590 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr16_-_1823104 0.587 NM_023936
MRPS34
mitochondrial ribosomal protein S34
chr7_-_148581403 0.585 NM_001203247
NM_001203248
NM_004456
NM_152998
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr8_-_80679897 0.583 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr8_+_110551916 0.579 NM_198120
EBAG9
estrogen receptor binding site associated, antigen, 9
chr8_+_110552309 0.577 NM_004215
EBAG9
estrogen receptor binding site associated, antigen, 9
chr18_+_20513277 0.563 NM_002894
RBBP8
retinoblastoma binding protein 8
chr7_-_148581377 0.561 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr13_-_21476895 0.560 NM_022459
XPO4
exportin 4
chr21_+_35445808 0.557 NM_032476
NM_006933
MRPS6
SLC5A3
mitochondrial ribosomal protein S6
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr9_-_103115094 0.555 NM_017746
TEX10
testis expressed 10
chr6_-_86352696 0.554 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr7_-_148581359 0.552 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr5_+_154134853 0.549 LARP1
La ribonucleoprotein domain family, member 1
chr1_+_1447495 0.543 NM_001170535
NM_018188
ATAD3A

ATPase family, AAA domain containing 3A

chr14_+_101193275 0.539 DLK1
delta-like 1 homolog (Drosophila)
chrX_+_153991106 0.537 DKC1
dyskeratosis congenita 1, dyskerin
chr16_+_23847321 0.535 PRKCB
protein kinase C, beta
chr22_+_20105068 0.533 RANBP1
RAN binding protein 1
chr10_+_105156430 0.533 PDCD11
programmed cell death 11
chr16_+_31191470 0.528 FUS
fused in sarcoma
chr22_-_21356351 0.527 NM_001008695
NM_030573
THAP7

THAP domain containing 7

chr20_-_1165116 0.527 NM_018354
TMEM74B
transmembrane protein 74B
chr19_+_45909466 0.526 NM_012099
CD3EAP
CD3e molecule, epsilon associated protein
chr1_-_109825767 0.526 NM_001005290
NM_001032291
NM_032636
PSRC1


proline/serine-rich coiled-coil 1


chr1_-_167523016 0.522 NM_003851
CREG1
cellular repressor of E1A-stimulated genes 1
chr3_+_38495778 0.520 NM_001106
ACVR2B
activin A receptor, type IIB
chr10_+_21823382 0.520 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr12_-_27090877 0.520 ASUN
asunder, spermatogenesis regulator homolog (Drosphila)
chr4_-_57301643 0.519 NM_002703
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr17_+_79679299 0.519 SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr2_+_86947387 0.518 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr14_+_33408458 0.517 NM_001164749
NM_001165893
NM_022123
NM_173159
NPAS3



neuronal PAS domain protein 3



chr1_-_54303933 0.517 TMEM48
transmembrane protein 48
chr1_-_167522979 0.516 CREG1
cellular repressor of E1A-stimulated genes 1
chr10_-_103543156 0.508 NM_006993
NPM3
nucleophosmin/nucleoplasmin 3
chr8_+_42752019 0.507 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr2_+_86947570 0.507 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr15_-_37391596 0.506 NM_172316
MEIS2
Meis homeobox 2
chr1_-_150208134 0.506 ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_+_54412007 0.506 NM_052940
LRRC42
leucine rich repeat containing 42
chr17_+_72427535 0.504 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr22_-_21355998 0.499 THAP7
THAP domain containing 7
chr6_-_41909386 0.499 NM_001136125
NM_001760
CCND3

cyclin D3

chr6_-_31865455 0.498 NM_006709
NM_025256
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr2_+_73441344 0.497 NM_006062
SMYD5
SMYD family member 5
chr5_-_176831385 0.496 F12
coagulation factor XII (Hageman factor)
chr10_+_21823093 0.494 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr7_+_2394428 0.493 NM_001037283
NM_003751
EIF3B

eukaryotic translation initiation factor 3, subunit B

chr19_+_11071792 0.493 NM_001128849
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr21_-_34143978 0.492 NM_013329
NM_016631
GCFC1

GC-rich sequence DNA-binding factor 1

chr1_+_167189948 0.491 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr4_-_185747051 0.490 ACSL1
acyl-CoA synthetase long-chain family member 1
chr10_-_103543148 0.489 NPM3
nucleophosmin/nucleoplasmin 3
chr2_-_214016332 0.487 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_-_12677347 0.482 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr2_-_220083394 0.482 ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_+_11071583 0.481 NM_001128844
NM_003072
SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr16_+_31191458 0.478 FUS
fused in sarcoma
chr10_+_105156382 0.477 NM_014976
PDCD11
programmed cell death 11
chr17_-_74236272 0.476 NM_052916
RNF157
ring finger protein 157
chr2_-_130939146 0.476 NM_001171083
NM_017751
NM_017951
SMPD4


sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)


chr1_+_162531349 0.476 UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1
chr17_+_79679370 0.476 NM_012140
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr20_+_31350387 0.475 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chrX_+_131157231 0.474 NM_001042453
NM_016542
MST4

serine/threonine protein kinase MST4

chr2_-_27579626 0.472 GTF3C2
general transcription factor IIIC, polypeptide 2, beta 110kDa
chr3_+_184081178 0.472 NM_006232
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr2_+_219575507 0.471 NM_014640
TTLL4
tubulin tyrosine ligase-like family, member 4
chr19_-_2456954 0.471 NM_032737
LMNB2
lamin B2
chr4_-_151936377 0.469 NM_001199282
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr3_-_13461802 0.468 NM_024923
NUP210
nucleoporin 210kDa
chr12_-_27091207 0.467 NM_018164
ASUN
asunder, spermatogenesis regulator homolog (Drosphila)
chr7_+_107384278 0.466 NM_024814
CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr12_+_103351451 0.466 NM_004316
ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr6_-_119670897 0.465 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr10_+_81107259 0.465 PPIF
peptidylprolyl isomerase F
chr14_+_29236171 0.464 NM_005249
FOXG1
forkhead box G1
chr22_+_21271619 0.462 NM_005207
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr12_+_104850641 0.462 NM_001173982
NM_018413
CHST11

carbohydrate (chondroitin 4) sulfotransferase 11

chr20_-_33872571 0.461 NM_002212
NM_181466
EIF6

eukaryotic translation initiation factor 6

chr2_+_73114501 0.455 NM_003124
SPR
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
chr9_-_124989755 0.454 NM_001242334
LHX6
LIM homeobox 6

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.