Motif ID: CUUUGGU

Z-value: 1.678


Mature miRNA associated with seed CUUUGGU:

NamemiRBase Accession
hsa-miR-9 MIMAT0000441



Activity profile for motif CUUUGGU.

activity profile for motif CUUUGGU


Sorted Z-values histogram for motif CUUUGGU

Sorted Z-values for motif CUUUGGU



Network of associatons between targets according to the STRING database.



First level regulatory network of CUUUGGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_1748285 4.089 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr2_+_173292306 4.040 NM_000210
NM_001079818
ITGA6

integrin, alpha 6

chr6_-_128841432 3.989 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr2_-_161350304 3.823 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr2_+_235860616 3.745 NM_014521
SH3BP4
SH3-domain binding protein 4
chr12_-_89746244 3.660 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr9_+_115913227 3.557 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr3_-_134093235 3.426 NM_016201
AMOTL2
angiomotin like 2
chr2_-_56151273 3.289 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr4_-_157892545 3.245 NM_016205
PDGFC
platelet derived growth factor C
chr10_+_124145584 3.187 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr5_+_135364583 3.171 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr6_-_169654047 3.028 NM_003247
THBS2
thrombospondin 2
chr10_+_124134093 2.948 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_-_225840660 2.902 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr1_+_99127146 2.862 NM_015976
NM_152238
SNX7

sorting nexin 7

chr10_+_124151818 2.861 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr3_-_98620452 2.833 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr3_-_120169493 2.779 NM_007085
FSTL1
follistatin-like 1
chr2_+_36583369 2.750 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr2_+_46524448 2.703 NM_001430
EPAS1
endothelial PAS domain protein 1
chr13_-_77460432 2.703 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr3_-_185542807 2.662 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr13_+_73633097 2.633 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr22_-_36236421 2.600 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr9_-_117880411 2.597 NM_002160
TNC
tenascin C
chr20_-_14318200 2.590 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr2_-_20425166 2.562 NM_001006946
SDC1
syndecan 1
chr1_-_154946859 2.555 NM_001130041
NM_001202859
NM_003029
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr8_-_134309448 2.526 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr3_+_30647901 2.421 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr22_-_36424397 2.346 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr2_-_20424627 2.333 NM_002997
SDC1
syndecan 1
chr3_+_105085553 2.316 NM_001243280
NM_001243281
NM_001243283
NM_001627
ALCAM



activated leukocyte cell adhesion molecule



chr9_-_107690526 2.301 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr2_-_235405692 2.170 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chrX_+_9754465 2.146 NM_001649
SHROOM2
shroom family member 2
chr21_+_46875402 2.104 NM_030582
COL18A1
collagen, type XVIII, alpha 1
chr8_-_18871163 2.095 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr5_-_16936371 2.055 NM_012334
MYO10
myosin X
chr1_+_169075869 1.985 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr8_-_18666295 1.879 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr4_-_7941092 1.852 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr5_-_127873734 1.842 NM_001999
FBN2
fibrillin 2
chr16_+_68771192 1.773 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr13_+_110959592 1.769 NM_001846
COL4A2
collagen, type IV, alpha 2
chr11_+_69924407 1.759 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr2_-_110371669 1.741 NM_144710
NM_178584
SEPT10

septin 10

chr16_+_8768403 1.724 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr1_-_154943001 1.690 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr1_+_151512760 1.689 NM_001126337
NM_020127
TUFT1

tuftelin 1

chr7_-_45960738 1.688 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr9_-_99329092 1.669 NM_001077181
CDC14B
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr3_+_33318911 1.665 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr10_-_125851850 1.649 NM_014863
NM_015892
CHST15

carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

chr6_+_116601282 1.634 NM_001080976
DSE
dermatan sulfate epimerase
chr5_+_34687663 1.602 NM_001145523
RAI14
retinoic acid induced 14
chr21_+_46825001 1.592 NM_130445
COL18A1
collagen, type XVIII, alpha 1
chr17_-_1389013 1.536 NM_001080950
MYO1C
myosin IC
chr16_+_8814567 1.530 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr2_-_166650770 1.527 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr17_-_1395950 1.505 NM_001080779
MYO1C
myosin IC
chr5_+_34656367 1.499 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chrX_+_105937067 1.497 NM_024539
RNF128
ring finger protein 128
chr3_+_57994087 1.487 NM_001164317
NM_001164318
NM_001164319
NM_001457
FLNB



filamin B, beta



chr11_+_101980736 1.474 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr14_+_105331581 1.466 NM_001112726
NM_015005
KIAA0284

KIAA0284

chrX_+_105969875 1.456 NM_194463
RNF128
ring finger protein 128
chr5_+_34656595 1.453 NM_001145520
RAI14
retinoic acid induced 14
chr21_-_44846927 1.447 NM_173354
SIK1
salt-inducible kinase 1
chr20_-_6104056 1.445 NM_017671
FERMT1
fermitin family member 1
chr5_+_34684611 1.408 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr2_+_64681270 1.406 NM_014181
LGALSL
lectin, galactoside-binding-like
chr11_+_101983170 1.402 NM_001195045
YAP1
Yes-associated protein 1
chr17_-_1394849 1.387 NM_033375
MYO1C
myosin IC
chr1_+_155100304 1.345 NM_004428
NM_182685
EFNA1

ephrin-A1

chr9_-_99382073 1.344 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr14_-_75078669 1.340 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr3_-_187463474 1.323 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr12_+_66218141 1.315 NM_003483
NM_003484
HMGA2

high mobility group AT-hook 2

chr6_-_82462374 1.310 NM_017633
FAM46A
family with sequence similarity 46, member A
chr11_+_12695851 1.308 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr11_-_79151694 1.304 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr21_-_28339405 1.278 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr16_+_8806825 1.270 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr22_+_38302085 1.253 NM_033386
MICALL1
MICAL-like 1
chr17_-_41174431 1.233 NM_006373
VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr6_+_116692098 1.211 NM_013352
DSE
dermatan sulfate epimerase
chr3_+_154798078 1.208 NM_007289
MME
membrane metallo-endopeptidase
chr22_-_36784055 1.199 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr13_-_40177355 1.198 NM_005780
LHFP
lipoma HMGIC fusion partner
chr17_+_73717515 1.195 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr1_+_7831326 1.174 NM_004781
VAMP3
vesicle-associated membrane protein 3 (cellubrevin)
chr6_+_158733691 1.171 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr3_-_129599220 1.157 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr10_+_99400441 1.153 NM_018425
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr1_-_108735362 1.150 NM_213651
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr8_-_42397048 1.145 NM_006749
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr13_-_33859835 1.140 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr1_+_32042085 1.133 NM_001204414
NM_022164
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr3_+_171757413 1.125 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr3_+_157154579 1.121 NM_002852
PTX3
pentraxin 3, long
chr16_-_4166185 1.115 NM_001116
ADCY9
adenylate cyclase 9
chr1_+_32043745 1.103 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr21_-_43346780 1.079 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr10_+_13142055 1.076 NM_001008211
NM_001008212
NM_001008213
NM_021980
OPTN



optineurin



chr3_+_154797910 1.071 NM_007288
MME
membrane metallo-endopeptidase
chrX_-_6145887 1.065 NM_020742
NLGN4X
neuroligin 4, X-linked
chr8_+_97505876 1.049 NM_002998
SDC2
syndecan 2
chr9_-_14398981 1.043 NM_001190738
NFIB
nuclear factor I/B
chr1_-_120612301 1.035 NM_001200001
NM_024408
NOTCH2

notch 2

chr22_-_45608346 1.020 NM_015264
KIAA0930
KIAA0930
chr3_-_187454247 1.017 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr3_-_187452669 1.007 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr13_+_113951461 1.005 NM_005561
LAMP1
lysosomal-associated membrane protein 1
chr1_+_100111430 0.995 NM_017734
PALMD
palmdelphin
chr7_-_129592794 0.992 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H

chr10_-_62703822 0.984 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr1_-_108742963 0.981 NM_013386
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr3_-_46037299 0.961 NM_024513
FYCO1
FYVE and coiled-coil domain containing 1
chr5_+_82767492 0.953 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chrX_-_100914816 0.931 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr3_-_129612371 0.912 NM_001128224
TMCC1
transmembrane and coiled-coil domain family 1
chr11_+_12399024 0.911 NM_018222
PARVA
parvin, alpha
chr4_+_154074269 0.904 NM_001130067
TRIM2
tripartite motif containing 2
chr19_-_57336373 0.898 NM_001146186
PEG3
paternally expressed 3
chr9_-_14314036 0.894 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr17_+_73720775 0.875 NM_001005619
ITGB4
integrin, beta 4
chr3_+_36421944 0.862 NM_003149
STAC
SH3 and cysteine rich domain
chr17_-_2304217 0.855 NM_020310
MNT
MAX binding protein
chr13_-_33780142 0.849 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr17_-_7298160 0.846 NM_001201576
NM_020360
PLSCR3

phospholipid scramblase 3

chr2_-_218808705 0.846 NM_022648
TNS1
tensin 1
chr2_+_11674241 0.828 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr3_+_154797644 0.819 NM_007287
MME
membrane metallo-endopeptidase
chr15_-_56285732 0.809 NM_006154
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr8_+_95653340 0.809 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr7_-_129592711 0.808 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr3_-_87040246 0.801 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr2_+_236402685 0.799 NM_001037131
NM_001244888
NM_014914
AGAP1


ArfGAP with GTPase domain, ankyrin repeat and PH domain 1


chr19_+_41222915 0.790 NM_025194
ITPKC
inositol-trisphosphate 3-kinase C
chrX_-_6146655 0.783 NM_181332
NLGN4X
neuroligin 4, X-linked
chr6_+_31126114 0.781 NM_001077511
NM_007109
TCF19

transcription factor 19

chr4_+_154125589 0.773 NM_015271
TRIM2
tripartite motif containing 2
chr19_-_56988698 0.769 NM_022103
ZNF667
zinc finger protein 667
chr5_-_131562934 0.767 NM_001017973
NM_004199
P4HA2

prolyl 4-hydroxylase, alpha polypeptide II

chr15_+_94841429 0.764 NM_001159643
NM_018349
MCTP2

multiple C2 domains, transmembrane 2

chr3_+_154797435 0.762 NM_000902
MME
membrane metallo-endopeptidase
chr18_+_29027731 0.759 NM_001944
DSG3
desmoglein 3
chr18_+_11851388 0.758 NM_020412
CHMP1B
charged multivesicular body protein 1B
chr6_+_148663728 0.758 NM_015278
SASH1
SAM and SH3 domain containing 1
chr1_-_241803203 0.756 NM_014322
OPN3
opsin 3
chr16_+_69220940 0.749 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr3_-_11761946 0.729 NM_014667
VGLL4
vestigial like 4 (Drosophila)
chr2_-_101767714 0.727 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr1_-_108507474 0.726 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr4_-_56412968 0.725 NM_004898
CLOCK
clock homolog (mouse)
chr12_+_3186520 0.715 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr3_-_11685395 0.712 NM_001128219
VGLL4
vestigial like 4 (Drosophila)
chr6_-_80656870 0.703 NM_022726
ELOVL4
ELOVL fatty acid elongase 4
chr14_-_78083109 0.694 NM_004863
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr21_-_36421586 0.689 NM_001754
RUNX1
runt-related transcription factor 1
chrX_+_49687212 0.675 NM_001127898
NM_001127899
CLCN5

chloride channel 5

chr6_-_167275657 0.674 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr13_-_33760215 0.673 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr16_-_66785511 0.668 NM_006141
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr6_+_35310317 0.665 NM_001171818
NM_001171819
NM_001171820
NM_006238
NM_177435
PPARD




peroxisome proliferator-activated receptor delta




chr5_-_178157597 0.661 NM_005649
ZNF354A
zinc finger protein 354A
chr3_+_171758289 0.651 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr5_-_131563481 0.651 NM_001017974
NM_001142598
NM_001142599
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr15_-_60690115 0.648 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chrY_+_15016018 0.645 NM_001122665
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr11_-_6502563 0.642 NM_001242854
NM_001242855
NM_001242856
NM_012402
ARFIP2



ADP-ribosylation factor interacting protein 2



chr4_+_30721865 0.640 NM_032456
NM_001173523
NM_002589
NM_032457
PCDH7



protocadherin 7



chr22_-_45636584 0.639 NM_001009880
KIAA0930
KIAA0930
chr14_-_67878770 0.631 NM_016445
PLEK2
pleckstrin 2
chr1_-_27481400 0.630 NM_003047
SLC9A1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr19_+_41725098 0.627 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr20_-_3149070 0.625 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr7_-_143582363 0.621 NM_001206941
FAM115A
family with sequence similarity 115, member A
chr11_-_17191287 0.620 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr13_-_30169795 0.615 NM_003045
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr17_-_62658311 0.611 NM_022739
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr8_-_19540093 0.609 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr9_+_130374466 0.606 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr3_+_101498285 0.606 NM_001134456
FAM55C
family with sequence similarity 55, member C
chr11_-_70935807 0.604 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr1_+_236849753 0.595 NM_001103
ACTN2
actinin, alpha 2
chr16_-_79634610 0.591 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr10_-_15210610 0.589 NM_004808
NMT2
N-myristoyltransferase 2
chr20_-_62258330 0.586 NM_012384
GMEB2
glucocorticoid modulatory element binding protein 2
chr3_-_52719514 0.583 NM_018313
PBRM1
polybromo 1
chr2_+_46926323 0.573 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr9_+_137533643 0.570 NM_000093
COL5A1
collagen, type V, alpha 1
chr2_+_191745546 0.563 NM_014905
GLS
glutaminase
chr10_-_104262404 0.563 NM_005736
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr16_-_85045119 0.563 NM_001145548
NM_017740
ZDHHC7

zinc finger, DHHC-type containing 7

chr8_-_19460005 0.562 NM_001130518
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr1_+_40506254 0.560 NM_001105530
NM_006367
CAP1

CAP, adenylate cyclase-associated protein 1 (yeast)

chr3_-_119812973 0.558 NM_001146156
NM_002093
GSK3B

glycogen synthase kinase 3 beta


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.88 1.03e-02 GO:0023052 signaling
2.61 1.63e-02 GO:0009653 anatomical structure morphogenesis
1.91 1.82e-02 GO:0007165 signal transduction
1.74 4.43e-02 GO:0051716 cellular response to stimulus

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.44 1.67e-04 GO:0044459 plasma membrane part
5.41 6.41e-04 GO:0031012 extracellular matrix
5.95 7.80e-04 GO:0005578 proteinaceous extracellular matrix
2.82 1.17e-03 GO:0005887 integral to plasma membrane
2.79 1.42e-03 GO:0031226 intrinsic to plasma membrane
7.72 3.96e-03 GO:0005912 adherens junction
1.82 7.29e-03 GO:0071944 cell periphery
6.93 7.87e-03 GO:0070161 anchoring junction
1.74 3.13e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
12.84 8.52e-04 GO:0005201 extracellular matrix structural constituent
1.40 4.52e-02 GO:0005515 protein binding