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• Activity deltas table
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Motif ID: E2F1..5.p2

Z-value: 6.472

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_135502445	27.626	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135502477	26.535		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135502521	21.398		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr11_-_33890931	12.593		LMO2	LIM domain only 2 (rhombotin-like 1)
chr7_-_99699030	12.364		MCM7	minichromosome maintenance complex component 7
chr7_-_99698993	12.282		MCM7	minichromosome maintenance complex component 7
chr7_-_99698916	11.485		MCM7	minichromosome maintenance complex component 7
chr11_-_33891361	11.153	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr7_-_99699426	11.067	NM_005916	MCM7	minichromosome maintenance complex component 7
chr6_-_52149541	10.852	NM_002388	MCM3	minichromosome maintenance complex component 3
chr22_+_35796104	10.270	NM_006739	MCM5	minichromosome maintenance complex component 5
chr8_-_124408665	10.242		ATAD2	ATPase family, AAA domain containing 2
chr8_-_124408688	10.064	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr11_-_33891258	10.053		LMO2	LIM domain only 2 (rhombotin-like 1)
chr8_-_124408458	9.811		ATAD2	ATPase family, AAA domain containing 2
chr16_-_89007605	9.704	NM_175931	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr22_+_35796154	9.695		MCM5	minichromosome maintenance complex component 5
chr6_-_52149516	9.567		MCM3	minichromosome maintenance complex component 3
chr2_-_136633934	9.180		MCM6	minichromosome maintenance complex component 6
chr6_-_52149472	9.022		MCM3	minichromosome maintenance complex component 3
chr8_+_48873533	8.996		MCM4	minichromosome maintenance complex component 4
chr11_-_19262424	8.904	NM_024680	E2F8	E2F transcription factor 8
chr10_+_62538250	8.818		CDK1	cyclin-dependent kinase 1
chr2_-_136634002	8.588	NM_005915	MCM6	minichromosome maintenance complex component 6
chr11_-_19263144	8.230		E2F8	E2F transcription factor 8
chr22_+_35796294	8.229		MCM5	minichromosome maintenance complex component 5
chr4_-_56502358	8.167	NM_006681	NMU	neuromedin U
chr6_-_27114577	8.004	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chr10_+_62538088	7.830	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr5_-_39074478	7.502		RICTOR	RPTOR independent companion of MTOR, complex 2
chr8_+_48873510	7.501		MCM4	minichromosome maintenance complex component 4
chr14_-_55369163	7.183	NM_000161 NM_001024024 NM_001024070 NM_001024071	GCH1	GTP cyclohydrolase 1
chr11_+_125495853	7.140		CHEK1	checkpoint kinase 1
chr8_+_48873446	6.939		MCM4	minichromosome maintenance complex component 4
chr15_-_64673569	6.402	NM_001029989 NM_014736	KIAA0101	KIAA0101
chr19_+_50887592	6.354	NM_002691	POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa
chr2_+_232573226	6.305	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr17_+_38444134	6.235	NM_001254	CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr1_+_242011544	6.199		EXO1	exonuclease 1
chr2_+_10262853	6.170	NM_001034	RRM2	ribonucleotide reductase M2
chr1_+_242011471	6.129	NM_130398	EXO1	exonuclease 1
chr3_+_127317271	6.117		MCM2	minichromosome maintenance complex component 2
chr17_+_38444130	6.007		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr6_+_27100784	6.005	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr6_-_153304093	5.974	NM_012177	FBXO5	F-box protein 5
chr7_+_50344255	5.910	NM_001220765 NM_001220766 NM_001220767 NM_001220768 NM_001220769 NM_001220770 NM_001220771 NM_001220772 NM_001220773 NM_001220774 NM_001220775 NM_001220776 NM_006060	IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr7_+_116593554	5.881		ST7	suppression of tumorigenicity 7
chr3_+_127317274	5.843		MCM2	minichromosome maintenance complex component 2
chr19_+_50887460	5.735		POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa
chr1_-_32801606	5.668	NM_023009	MARCKSL1	MARCKS-like 1
chr3_+_121554029	5.636	NM_018456	EAF2	ELL associated factor 2
chr8_-_120868034	5.584	NM_024094	DSCC1	defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr17_+_30264039	5.523	NM_015355	SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr17_+_38444151	5.509		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr2_+_10262694	5.443	NM_001165931	RRM2	ribonucleotide reductase M2
chr1_-_149783910	5.416	NM_001024599 NM_001161334	HIST2H2BF	histone cluster 2, H2bf
chr6_-_27100528	5.398	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr2_+_232573249	5.323		PTMA	prothymosin, alpha
chr11_+_65029312	5.322	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chr5_-_79950307	5.308		DHFR	dihydrofolate reductase
chr10_+_13203547	5.279	NM_018518 NM_182751	MCM10	minichromosome maintenance complex component 10
chr13_+_34392254	5.259		RFC3	replication factor C (activator 1) 3, 38kDa
chr7_-_148581403	5.209	NM_001203247 NM_001203248 NM_004456 NM_152998	EZH2	enhancer of zeste homolog 2 (Drosophila)
chrX_+_24712063	5.097	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr3_+_127317212	5.030	NM_004526	MCM2	minichromosome maintenance complex component 2
chr15_+_91260575	5.024	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chr1_-_149399159	5.002	NM_001024599	HIST2H2BF	histone cluster 2, H2bf
chr7_-_148581297	5.001		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr22_+_20105068	4.952		RANBP1	RAN binding protein 1
chr7_-_148581359	4.918		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148581379	4.913		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148581377	4.825		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr6_+_37137882	4.807	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr13_+_34392205	4.767	NM_002915 NM_181558	RFC3	replication factor C (activator 1) 3, 38kDa
chrX_-_53449548	4.723		SMC1A	structural maintenance of chromosomes 1A
chrX_-_152736015	4.683		TREX2 HAUS7	three prime repair exonuclease 2 HAUS augmin-like complex, subunit 7
chr17_+_30264054	4.654		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr14_-_50155097	4.627	NM_001197330 NM_001197331 NM_002692	POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr20_-_5100443	4.598	NM_182649	PCNA	proliferating cell nuclear antigen
chr16_-_85722503	4.598		GINS2	GINS complex subunit 2 (Psf2 homolog)
chr8_+_26435590	4.595		DPYSL2	dihydropyrimidinase-like 2
chr14_-_50154920	4.577		POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr5_-_79950348	4.516		DHFR	dihydrofolate reductase
chr3_-_141868208	4.483	NM_001178138 NM_001178139	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr15_-_66648991	4.466	NM_017858	TIPIN	TIMELESS interacting protein
chr2_+_47630246	4.460	NM_000251	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr3_-_138665981	4.427	NM_023067	FOXL2	forkhead box L2
chr15_-_41624760	4.415	NM_007280	OIP5	Opa interacting protein 5
chr14_-_55658205	4.415	NM_001146015 NM_014750	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr16_+_88870185	4.380	NM_030928	CDT1	chromatin licensing and DNA replication factor 1
chr16_-_85722587	4.363	NM_016095	GINS2	GINS complex subunit 2 (Psf2 homolog)
chr1_+_33116748	4.344	NM_001135255 NM_005610 NM_001135256	RBBP4	retinoblastoma binding protein 4
chr1_+_93544786	4.333	NM_001164391 NM_001164392 NM_001164393 NM_007358	MTF2	metal response element binding transcription factor 2
chrX_+_131157231	4.332	NM_001042453 NM_016542	MST4	serine/threonine protein kinase MST4
chrX_+_131157635	4.314	NM_001042452	MST4	serine/threonine protein kinase MST4
chr17_+_30264261	4.290
chr6_+_27775898	4.250	NM_003509	HIST1H2AI HIST1H2AM HIST1H3F	histone cluster 1, H2ai histone cluster 1, H2am histone cluster 1, H3f
chr22_-_20104695	4.245		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr1_+_46049659	4.220	NM_001195193 NM_002482 NM_152298	NASP	nuclear autoantigenic sperm protein (histone-binding)
chr17_+_30264140	4.155		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr7_-_73668693	4.102		RFC2	replication factor C (activator 1) 2, 40kDa
chr8_-_95907423	4.084	NM_057749	CCNE2	cyclin E2
chr1_+_212209129	4.033		DTL	denticleless homolog (Drosophila)
chrX_+_123095555	4.019	NM_001042750 NM_001042751 NM_006603	STAG2	stromal antigen 2
chr6_+_24775640	3.986	NM_001251991	GMNN	geminin, DNA replication inhibitor
chr5_-_79950783	3.986	NM_000791	DHFR	dihydrofolate reductase
chr7_-_158497432	3.980	NM_017760	NCAPG2	non-SMC condensin II complex, subunit G2
chr5_-_37371078	3.944		NUP155	nucleoporin 155kDa
chr9_+_100745584	3.943		ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr22_+_20105076	3.936		RANBP1	RAN binding protein 1
chr1_-_225615701	3.935		LBR	lamin B receptor
chr7_+_139044604	3.930	NM_016019	LUC7L2	LUC7-like 2 (S. cerevisiae)
chr1_-_26185847	3.926	NM_024037	C1orf135	chromosome 1 open reading frame 135
chr22_+_19467413	3.902	NM_001178010 NM_001178011 NM_003504	CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr7_+_120590816	3.837	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr16_+_2039945	3.814	NM_004209	SYNGR3	synaptogyrin 3
chr20_+_25388320	3.813	NM_021067	GINS1	GINS complex subunit 1 (Psf1 homolog)
chr6_+_24775154	3.796	NM_001251989 NM_001251990 NM_015895	GMNN	geminin, DNA replication inhibitor
chr3_+_16926451	3.773	NM_001144382	PLCL2	phospholipase C-like 2
chr16_+_88870214	3.744		CDT1	chromatin licensing and DNA replication factor 1
chr15_+_32907690	3.703	NM_014783 NM_199357	ARHGAP11A	Rho GTPase activating protein 11A
chr1_-_26232643	3.687	NM_203401	STMN1	stathmin 1
chr17_+_30264065	3.652		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr2_+_48010220	3.635	NM_000179	MSH6	mutS homolog 6 (E. coli)
chr10_-_58121019	3.600	NM_001005413 NM_007057 NM_032997	ZWINT	ZW10 interactor
chr10_-_58121011	3.600		ZWINT	ZW10 interactor
chr2_+_47630291	3.597		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr3_+_44803280	3.595		KIF15	kinesin family member 15
chr1_+_212208918	3.588	NM_016448	DTL	denticleless homolog (Drosophila)
chrX_-_137793394	3.561		FGF13	fibroblast growth factor 13
chr11_+_125496123	3.549	NM_001274	CHEK1	checkpoint kinase 1
chr3_+_44803208	3.522	NM_020242	KIF15	kinesin family member 15
chr1_-_28241233	3.506	NM_002946	RPA2	replication protein A2, 32kDa
chr22_-_20104745	3.496	NM_022727 NM_182984	TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr1_-_28240953	3.496		RPA2	replication protein A2, 32kDa
chrX_+_123095598	3.495		STAG2	stromal antigen 2
chr7_+_139044696	3.475		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr22_+_20105145	3.465		RANBP1	RAN binding protein 1
chr2_+_74781511	3.455	NM_001381	DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr6_+_27806322	3.446	NM_003520	HIST1H2BN	histone cluster 1, H2bn
chr3_+_142838596	3.446	NM_004267	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr1_-_47779651	3.439	NM_001048166 NM_003035	STIL	SCL/TAL1 interrupting locus
chr5_-_37370886	3.435	NM_004298	NUP155	nucleoporin 155kDa
chr1_-_33502484	3.431	NM_001199199 NM_001625 NM_013411	AK2	adenylate kinase 2
chr8_-_27695288	3.427	NM_018492	PBK	PDZ binding kinase
chr9_+_86595636	3.386	NM_024945	RMI1	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chr7_+_139044701	3.386		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr5_-_37371182	3.383	NM_153485	NUP155	nucleoporin 155kDa
chr16_-_3030473	3.374	NM_004203 NM_182687	PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr2_+_47630190	3.362		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr6_-_27782517	3.356	NM_021066	HIST1H2AJ	histone cluster 1, H2aj
chr7_-_73668732	3.348	NM_002914 NM_181471	RFC2	replication factor C (activator 1) 2, 40kDa
chr15_+_41624891	3.340	NM_001243142 NM_001243143 NM_001243144 NM_016359 NM_018454	NUSAP1	nucleolar and spindle associated protein 1
chr22_+_19467467	3.312		CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr5_+_43121592	3.305		ZNF131	zinc finger protein 131
chrX_-_131623994	3.301	NM_001170704	MBNL3	muscleblind-like 3 (Drosophila)
chr7_+_139044669	3.295		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr20_+_25388328	3.266		GINS1	GINS complex subunit 1 (Psf1 homolog)
chr16_+_58426297	3.262	NM_001126129 NM_001126130 NM_022770	GINS3	GINS complex subunit 3 (Psf3 homolog)
chr8_+_128748476	3.234		MYC	v-myc myelocytomatosis viral oncogene homolog (avian)
chr1_-_26233367	3.231	NM_203399	STMN1	stathmin 1
chr1_-_225615787	3.197	NM_002296	LBR	lamin B receptor
chr3_-_121553907	3.169	NM_001023570 NM_001023571	IQCB1	IQ motif containing B1
chr11_+_4115923	3.160	NM_001033	RRM1	ribonucleotide reductase M1
chr16_-_3030391	3.152		PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr3_-_148804122	3.137	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr16_-_3767449	3.053	NM_016292	TRAP1	TNF receptor-associated protein 1
chr4_-_105412466	3.048	NM_025212	CXXC4	CXXC finger protein 4
chr11_+_4116059	3.043		RRM1	ribonucleotide reductase M1
chr16_+_29817426	3.043		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr11_+_47586887	3.032	NM_001143984 NM_175732	PTPMT1	protein tyrosine phosphatase, mitochondrial 1
chr5_+_43121641	2.943	NM_003432	ZNF131	zinc finger protein 131
chr1_-_54304107	2.931	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chr8_+_128748312	2.904	NM_002467	MYC	v-myc myelocytomatosis viral oncogene homolog (avian)
chr12_-_133263899	2.873	NM_006231	POLE	polymerase (DNA directed), epsilon
chr12_-_31479120	2.870	NM_001135811 NM_021238 NM_001135812	FAM60A	family with sequence similarity 60, member A
chr22_+_20105095	2.821		RANBP1	RAN binding protein 1
chr5_+_126112819	2.807	NM_001198557	LMNB1	lamin B1
chr15_+_41625052	2.795		NUSAP1	nucleolar and spindle associated protein 1
chr10_-_75006963	2.768	NM_015190	DNAJC9	DnaJ (Hsp40) homolog, subfamily C, member 9
chr21_-_34960937	2.760	NM_017613	DONSON	downstream neighbor of SON
chr3_+_14220227	2.751	NM_014463	LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_38158176	2.732		CDCA8	cell division cycle associated 8
chr1_-_26232890	2.730	NM_001145454 NM_005563	STMN1	stathmin 1
chr8_+_21777216	2.701		XPO7	exportin 7
chr19_-_41859830	2.694	NM_000660	TGFB1	transforming growth factor, beta 1
chr3_+_14989076	2.683	NM_003298	NR2C2	nuclear receptor subfamily 2, group C, member 2
chr9_+_100745456	2.682	NM_006401	ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr1_+_38158189	2.665		CDCA8	cell division cycle associated 8
chr4_+_129730772	2.637	NM_024900 NM_199320	PHF17	PHD finger protein 17
chr1_+_62902708	2.618		USP1	ubiquitin specific peptidase 1
chr1_-_54303933	2.615		TMEM48	transmembrane protein 48
chr6_+_20402040	2.606	NM_001949	E2F3	E2F transcription factor 3
chr3_+_14220329	2.588		LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_-_205719273	2.567		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr3_-_48229800	2.551	NM_001789 NM_201567	CDC25A	cell division cycle 25 homolog A (S. pombe)
chr11_-_57103324	2.543	NM_003146	SSRP1	structure specific recognition protein 1
chr22_-_29137776	2.539	NM_001005735 NM_007194 NM_145862	CHEK2	checkpoint kinase 2
chr9_+_139702389	2.524		C9orf86	chromosome 9 open reading frame 86
chr4_-_122744782	2.518		CCNA2	cyclin A2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
4.71	1.33e-39	GO:0007049	cell cycle
5.19	3.73e-37	GO:0022402	cell cycle process
5.59	2.89e-36	GO:0022403	cell cycle phase
5.72	5.54e-34	GO:0051276	chromosome organization
10.71	5.73e-32	GO:0006260	DNA replication
5.68	8.64e-32	GO:0000278	mitotic cell cycle
5.47	1.10e-29	GO:0006259	DNA metabolic process
3.06	3.85e-24	GO:0006996	organelle organization
16.01	2.61e-23	GO:0006261	DNA-dependent DNA replication
6.61	4.08e-23	GO:0051325	interphase
6.60	1.55e-22	GO:0051329	interphase of mitotic cell cycle
2.57	4.03e-22	GO:0090304	nucleic acid metabolic process
2.29	1.81e-20	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
5.86	3.16e-20	GO:0010564	regulation of cell cycle process
4.26	1.02e-18	GO:0051726	regulation of cell cycle
8.57	1.33e-17	GO:0000082	G1/S transition of mitotic cell cycle
8.60	2.23e-16	GO:0071103	DNA conformation change
4.99	2.34e-16	GO:0000279	M phase
9.46	2.86e-16	GO:0051320	S phase
22.63	3.13e-16	GO:0006271	DNA strand elongation involved in DNA replication
6.69	7.53e-16	GO:0000075	cell cycle checkpoint
21.01	1.71e-15	GO:0022616	DNA strand elongation
9.28	2.25e-15	GO:0000084	S phase of mitotic cell cycle
6.45	2.51e-15	GO:0071156	regulation of cell cycle arrest
1.99	4.86e-15	GO:0034641	cellular nitrogen compound metabolic process
2.12	6.31e-15	GO:0071841	cellular component organization or biogenesis at cellular level
5.18	7.02e-15	GO:0006281	DNA repair
2.15	8.72e-15	GO:0071842	cellular component organization at cellular level
1.78	1.12e-14	GO:0044260	cellular macromolecule metabolic process
1.95	2.96e-14	GO:0006807	nitrogen compound metabolic process
4.09	1.17e-13	GO:0006974	response to DNA damage stimulus
5.51	3.77e-13	GO:0000280	nuclear division
5.51	3.77e-13	GO:0007067	mitosis
8.49	4.49e-13	GO:0006323	DNA packaging
22.76	7.17e-13	GO:0006270	DNA-dependent DNA replication initiation
5.32	1.11e-12	GO:0000087	M phase of mitotic cell cycle
5.30	1.26e-12	GO:0048285	organelle fission
8.89	2.76e-12	GO:0065004	protein-DNA complex assembly
8.34	1.17e-11	GO:0071824	protein-DNA complex subunit organization
1.83	1.53e-11	GO:0071840	cellular component organization or biogenesis
1.64	1.57e-11	GO:0043170	macromolecule metabolic process
22.06	1.70e-11	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
8.68	2.06e-11	GO:0034728	nucleosome organization
7.24	2.10e-11	GO:0006310	DNA recombination
1.84	2.27e-11	GO:0016043	cellular component organization
9.08	3.45e-11	GO:0031497	chromatin assembly
7.23	7.63e-11	GO:0006333	chromatin assembly or disassembly
3.97	7.64e-11	GO:0006325	chromatin organization
12.26	7.73e-11	GO:0051053	negative regulation of DNA metabolic process
8.85	2.60e-10	GO:0006334	nucleosome assembly
2.24	9.79e-10	GO:0034645	cellular macromolecule biosynthetic process
27.58	1.84e-09	GO:0071897	DNA biosynthetic process
2.21	1.92e-09	GO:0009059	macromolecule biosynthetic process
13.66	3.69e-09	GO:0008156	negative regulation of DNA replication
6.32	4.73e-09	GO:0051052	regulation of DNA metabolic process
1.45	1.51e-08	GO:0044238	primary metabolic process
19.35	1.76e-08	GO:0032201	telomere maintenance via semi-conservative replication
4.13	2.12e-08	GO:0051301	cell division
7.44	2.65e-08	GO:0007059	chromosome segregation
15.56	3.35e-08	GO:0006312	mitotic recombination
18.39	3.44e-08	GO:0000722	telomere maintenance via recombination
17.51	6.41e-08	GO:0090329	regulation of DNA-dependent DNA replication
20.68	8.69e-08	GO:0007062	sister chromatid cohesion
2.71	1.00e-07	GO:0033554	cellular response to stress
7.85	1.51e-07	GO:0000216	M/G1 transition of mitotic cell cycle
7.85	1.51e-07	GO:0006275	regulation of DNA replication
18.39	3.52e-07	GO:2000104	negative regulation of DNA-dependent DNA replication
1.40	1.13e-06	GO:0044237	cellular metabolic process
16.55	1.16e-06	GO:0006298	mismatch repair
3.62	1.20e-06	GO:0034622	cellular macromolecular complex assembly
19.61	1.85e-06	GO:0006297	nucleotide-excision repair, DNA gap filling
9.59	2.78e-06	GO:0000723	telomere maintenance
1.80	3.00e-06	GO:0044249	cellular biosynthetic process
12.68	3.00e-06	GO:0010833	telomere maintenance via telomere lengthening
9.39	3.64e-06	GO:0032200	telomere organization
10.65	3.90e-06	GO:0000070	mitotic sister chromatid segregation
1.77	4.43e-06	GO:0009058	biosynthetic process
1.19	5.35e-06	GO:0009987	cellular process
9.87	9.52e-06	GO:0000819	sister chromatid segregation
27.58	1.29e-05	GO:0000731	DNA synthesis involved in DNA repair
1.33	2.07e-05	GO:0008152	metabolic process
2.94	3.23e-05	GO:0034621	cellular macromolecular complex subunit organization
2.54	5.88e-05	GO:0065003	macromolecular complex assembly
13.37	7.79e-05	GO:0002200	somatic diversification of immune receptors
2.12	8.89e-05	GO:0044085	cellular component biogenesis
14.30	3.15e-04	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus
14.30	3.15e-04	GO:0016444	somatic cell DNA recombination
18.39	3.87e-04	GO:0030174	regulation of DNA-dependent DNA replication initiation
2.27	4.33e-04	GO:0043933	macromolecular complex subunit organization
2.38	5.11e-04	GO:0071844	cellular component assembly at cellular level
2.11	5.58e-04	GO:0022607	cellular component assembly
5.43	8.22e-04	GO:0007126	meiosis
5.43	8.22e-04	GO:0051327	M phase of meiotic cell cycle
5.37	9.39e-04	GO:0051321	meiotic cell cycle
2.49	1.48e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
9.49	1.55e-03	GO:0006284	base-excision repair
2.46	2.03e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
20.43	2.07e-03	GO:0000076	DNA replication checkpoint
20.43	2.07e-03	GO:0002566	somatic diversification of immune receptors via somatic mutation
20.43	2.07e-03	GO:0016446	somatic hypermutation of immunoglobulin genes
20.43	2.07e-03	GO:0032297	negative regulation of DNA-dependent DNA replication initiation
4.60	2.43e-03	GO:0050657	nucleic acid transport
4.60	2.43e-03	GO:0050658	RNA transport
4.60	2.43e-03	GO:0051236	establishment of RNA localization
3.44	3.32e-03	GO:0009314	response to radiation
4.48	3.35e-03	GO:0006403	RNA localization
4.69	4.55e-03	GO:0051028	mRNA transport
4.56	6.32e-03	GO:0031570	DNA integrity checkpoint
1.49	8.96e-03	GO:0060255	regulation of macromolecule metabolic process
24.51	9.66e-03	GO:0000710	meiotic mismatch repair
11.61	9.67e-03	GO:0016445	somatic diversification of immunoglobulins
4.09	9.91e-03	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
5.66	1.13e-02	GO:0006289	nucleotide-excision repair
15.32	1.22e-02	GO:0007091	mitotic metaphase/anaphase transition
1.57	1.26e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
7.18	1.48e-02	GO:0006283	transcription-coupled nucleotide-excision repair
3.07	1.80e-02	GO:0007346	regulation of mitotic cell cycle
2.77	1.90e-02	GO:0016568	chromatin modification
4.42	2.02e-02	GO:0060249	anatomical structure homeostasis
21.01	2.20e-02	GO:0007064	mitotic sister chromatid cohesion
5.81	2.57e-02	GO:0009411	response to UV
1.53	2.61e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.58	2.88e-02	GO:2000112	regulation of cellular macromolecule biosynthetic process
13.13	2.94e-02	GO:0016447	somatic recombination of immunoglobulin gene segments
6.54	3.05e-02	GO:0007051	spindle organization
1.67	3.16e-02	GO:0016070	RNA metabolic process
9.59	3.28e-02	GO:0002377	immunoglobulin production
1.99	3.77e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.99	3.77e-02	GO:0031324	negative regulation of cellular metabolic process
9.19	4.28e-02	GO:0002440	production of molecular mediator of immune response
18.39	4.32e-02	GO:0045910	negative regulation of DNA recombination

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.11	2.42e-44	GO:0005634	nucleus
3.23	9.35e-44	GO:0044428	nuclear part
3.36	3.33e-39	GO:0031981	nuclear lumen
6.08	1.22e-36	GO:0005694	chromosome
2.96	1.53e-36	GO:0070013	intracellular organelle lumen
2.90	2.35e-35	GO:0043233	organelle lumen
2.86	4.37e-35	GO:0031974	membrane-enclosed lumen
3.69	4.89e-34	GO:0005654	nucleoplasm
6.05	1.08e-29	GO:0044427	chromosomal part
1.53	6.17e-27	GO:0043231	intracellular membrane-bounded organelle
1.53	8.24e-27	GO:0043227	membrane-bounded organelle
1.45	1.50e-25	GO:0043229	intracellular organelle
1.45	2.45e-25	GO:0043226	organelle
1.83	2.54e-25	GO:0044446	intracellular organelle part
1.80	2.11e-24	GO:0044422	organelle part
1.31	2.36e-21	GO:0044424	intracellular part
1.28	4.26e-19	GO:0005622	intracellular
6.97	2.86e-18	GO:0000228	nuclear chromosome
6.49	3.41e-17	GO:0000785	chromatin
2.19	6.33e-17	GO:0043228	non-membrane-bounded organelle
2.19	6.33e-17	GO:0043232	intracellular non-membrane-bounded organelle
3.53	7.44e-15	GO:0044451	nucleoplasm part
1.88	3.75e-14	GO:0032991	macromolecular complex
9.63	8.07e-14	GO:0032993	protein-DNA complex
6.73	1.67e-13	GO:0044454	nuclear chromosome part
1.85	4.70e-10	GO:0043234	protein complex
13.37	6.41e-09	GO:0005657	replication fork
10.10	1.07e-08	GO:0000786	nucleosome
27.58	2.37e-06	GO:0042555	MCM complex
14.71	5.93e-06	GO:0043596	nuclear replication fork
5.17	6.12e-06	GO:0000793	condensed chromosome
17.16	1.26e-05	GO:0030894	replisome
17.16	1.26e-05	GO:0043601	nuclear replisome
3.92	2.01e-05	GO:0016604	nuclear body
4.40	7.59e-04	GO:0000775	chromosome, centromeric region
15.32	2.24e-03	GO:0032300	mismatch repair complex
1.07	4.86e-03	GO:0044464	cell part
1.07	4.95e-03	GO:0005623	cell
5.11	5.26e-03	GO:0000790	nuclear chromatin
3.49	5.89e-03	GO:0005819	spindle
6.40	6.64e-03	GO:0034708	methyltransferase complex
6.40	6.64e-03	GO:0035097	histone methyltransferase complex
18.39	7.95e-03	GO:0035098	ESC/E(Z) complex
5.89	1.24e-02	GO:0000794	condensed nuclear chromosome
2.29	1.66e-02	GO:0005730	nucleolus
2.12	1.85e-02	GO:0015630	microtubule cytoskeleton
5.45	2.19e-02	GO:0016605	PML body
5.26	2.86e-02	GO:0000922	spindle pole
22.06	4.43e-02	GO:0005658	alpha DNA polymerase:primase complex
22.06	4.43e-02	GO:0005663	DNA replication factor C complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.38	3.66e-17	GO:0003677	DNA binding
2.06	1.41e-16	GO:0003676	nucleic acid binding
5.80	8.88e-11	GO:0043566	structure-specific DNA binding
1.20	2.14e-10	GO:0005488	binding
9.19	5.07e-08	GO:0003697	single-stranded DNA binding
1.34	1.16e-07	GO:0005515	protein binding
5.78	1.58e-07	GO:0003690	double-stranded DNA binding
8.44	1.74e-07	GO:0008094	DNA-dependent ATPase activity
9.19	4.70e-06	GO:0003684	damaged DNA binding
18.39	8.16e-06	GO:0030983	mismatched DNA binding
30.64	2.31e-05	GO:0032135	DNA insertion or deletion binding
1.74	2.32e-05	GO:0000166	nucleotide binding
4.29	2.41e-05	GO:0003682	chromatin binding
12.26	3.74e-05	GO:0003887	DNA-directed DNA polymerase activity
20.06	4.33e-05	GO:0000217	DNA secondary structure binding
10.90	1.05e-04	GO:0034061	DNA polymerase activity
1.86	3.39e-04	GO:0005524	ATP binding
1.83	5.53e-04	GO:0032559	adenyl ribonucleotide binding
1.82	6.49e-04	GO:0030554	adenyl nucleotide binding
1.67	3.49e-03	GO:0035639	purine ribonucleoside triphosphate binding
36.77	5.48e-03	GO:0000404	loop DNA binding
36.77	5.48e-03	GO:0032139	dinucleotide insertion or deletion binding
36.77	5.48e-03	GO:0032142	single guanine insertion binding
36.77	5.48e-03	GO:0032356	oxidized DNA binding
36.77	5.48e-03	GO:0032357	oxidized purine DNA binding
1.64	6.04e-03	GO:0032553	ribonucleotide binding
1.64	6.04e-03	GO:0032555	purine ribonucleotide binding
1.64	7.16e-03	GO:0017076	purine nucleotide binding
27.58	2.15e-02	GO:0032138	single base insertion or deletion binding
27.58	2.15e-02	GO:0032405	MutLalpha complex binding
4.05	2.24e-02	GO:0016779	nucleotidyltransferase activity