Motif ID: ELF1,2,4.p2

Z-value: 1.383


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ELF4chrX_-_1292444220.692.9e-03Click!
ELF1chr13_-_416350720.421.0e-01Click!
ELF2chr4_-_140060601-0.341.9e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_9834778 1.705 NM_001198780
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chrX_+_64887534 1.370 MSN
moesin
chrX_+_64887510 1.359 NM_002444
MSN
moesin
chr8_-_29206321 1.336 NM_057158
DUSP4
dual specificity phosphatase 4
chrX_+_64887593 1.331 MSN
moesin
chr22_-_19512859 1.259 NM_001130861
NM_003277
CLDN5

claudin 5

chr17_+_40985412 1.259 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr10_+_3110818 1.240 NM_001242339
PFKP
phosphofructokinase, platelet
chr11_-_58345593 1.239 NM_001143995
LPXN
leupaxin
chr1_-_169336999 1.139 NM_013330
NM_197972
NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr12_+_48499655 1.047 NM_001166686
PFKM
phosphofructokinase, muscle
chr1_+_151032150 1.026 NM_006818
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr14_+_61788398 0.992 NM_006255
PRKCH
protein kinase C, eta
chr18_-_52988916 0.957 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr5_+_140071220 0.953 HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr8_+_22462532 0.951 NM_021174
KIAA1967
KIAA1967
chr20_+_19867075 0.935 NM_001242581
RIN2
Ras and Rab interactor 2
chr4_+_90816002 0.889 NM_007351
MMRN1
multimerin 1
chr4_-_48782281 0.886 NM_015030
FRYL
FRY-like
chr3_-_121379757 0.878 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chrX_+_119737984 0.877 MCTS1
malignant T cell amplified sequence 1
chr1_+_153330329 0.857 NM_002965
S100A9
S100 calcium binding protein A9
chr7_-_105752650 0.844 SYPL1
synaptophysin-like 1
chr10_+_8097350 0.838 GATA3
GATA binding protein 3
chr10_+_45496272 0.836 NM_006963
ZNF22
zinc finger protein 22 (KOX 15)
chr14_-_67878859 0.836 PLEK2
pleckstrin 2
chr10_+_71075609 0.834 NM_033496
HK1
hexokinase 1
chr14_-_100842676 0.834 NM_173701
NM_213645
WARS

tryptophanyl-tRNA synthetase

chr10_-_1102643 0.821 IDI1
isopentenyl-diphosphate delta isomerase 1
chr14_-_100842637 0.821 WARS
tryptophanyl-tRNA synthetase
chr8_+_22462267 0.778 KIAA1967
KIAA1967
chr14_-_67878770 0.768 NM_016445
PLEK2
pleckstrin 2
chr6_+_30294224 0.767


chr8_+_22462273 0.762 KIAA1967
KIAA1967
chr17_+_40985434 0.760 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr5_+_892950 0.754 NM_001166260
NM_004237
TRIP13

thyroid hormone receptor interactor 13

chr10_+_12238208 0.754 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr10_+_129845806 0.753 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr20_+_30135187 0.750


chr3_-_121379701 0.750 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr12_-_21654484 0.750 NM_002907
NM_032941
RECQL

RecQ protein-like (DNA helicase Q1-like)

chr3_+_62304667 0.748 C3orf14
chromosome 3 open reading frame 14
chr14_-_23388294 0.747 RBM23
RNA binding motif protein 23
chr10_+_1102741 0.746 NM_014023
WDR37
WD repeat domain 37
chr18_+_3262110 0.745 NM_033546
MYL12B
myosin, light chain 12B, regulatory
chr17_-_62097937 0.733 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr1_-_31230673 0.724 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chrX_+_15518899 0.716 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr19_-_49243836 0.710 NM_017805
RASIP1
Ras interacting protein 1
chr8_+_22462286 0.703 KIAA1967
KIAA1967
chr1_-_43637969 0.696 NM_006824
NM_001159936
EBNA1BP2

EBNA1 binding protein 2

chr19_-_19754452 0.695 NM_016573
GMIP
GEM interacting protein
chr8_+_15397761 0.694 TUSC3
tumor suppressor candidate 3
chr11_-_89224413 0.677 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr7_+_93551015 0.675 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr7_+_44240555 0.675 YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr14_-_23388359 0.673 RBM23
RNA binding motif protein 23
chrX_+_119738542 0.672 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr10_+_12238179 0.663 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr10_+_12238194 0.663 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr17_+_40985444 0.660 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr15_-_42264749 0.656 NM_139265
EHD4
EH-domain containing 4
chr7_+_44240606 0.655 YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr15_-_42264687 0.645 EHD4
EH-domain containing 4
chr1_-_31230594 0.644 LAPTM5
lysosomal protein transmembrane 5
chr9_+_100396079 0.639 NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr14_-_100842623 0.639 WARS
tryptophanyl-tRNA synthetase
chr9_+_127631500 0.637 ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr2_+_33661392 0.632 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_-_103266577 0.630 NM_001135146
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr5_+_153418544 0.629 MFAP3
microfibrillar-associated protein 3
chr20_-_1373571 0.628 FKBP1A
FK506 binding protein 1A, 12kDa
chr8_+_82192717 0.627 NM_001444
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr5_-_102455781 0.624 NM_017676
GIN1
gypsy retrotransposon integrase 1
chr1_-_183604850 0.624 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr11_-_417324 0.617 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr19_+_38755238 0.616 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755422 0.614 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr17_+_40985416 0.614 NM_005789
NM_176863
PSME3

proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

chr7_-_5569200 0.610 ACTB
actin, beta
chr12_-_21654206 0.609 RECQL
RecQ protein-like (DNA helicase Q1-like)
chr18_+_3262184 0.605 MYL12B
myosin, light chain 12B, regulatory
chr9_+_116263706 0.588 NM_130795
RGS3
regulator of G-protein signaling 3
chr11_+_20385686 0.584 NM_001098523
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr3_+_9834178 0.580 NM_001024959
NM_001024960
ARPC4

actin related protein 2/3 complex, subunit 4, 20kDa

chr11_+_61560352 0.580 FEN1
flap structure-specific endonuclease 1
chr5_+_162932550 0.578 NM_013283
MAT2B
methionine adenosyltransferase II, beta
chr5_+_34656482 0.573 RAI14
retinoic acid induced 14
chr7_-_105752718 0.572 NM_182715
SYPL1
synaptophysin-like 1
chr3_-_112280359 0.570 NM_022488
ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chr5_+_110074740 0.569 NM_138773
SLC25A46
solute carrier family 25, member 46
chr15_+_101420004 0.568 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr17_+_1945276 0.565 NM_080822
OVCA2
ovarian tumor suppressor candidate 2
chr19_+_17420216 0.564 NM_024050
DDA1
DET1 and DDB1 associated 1
chrX_-_134185978 0.563 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr2_-_175547471 0.563 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr11_-_71823737 0.561 NM_014042
C11orf51
chromosome 11 open reading frame 51
chr3_-_112280764 0.559 ATG3
ATG3 autophagy related 3 homolog (S. cerevisiae)
chr4_-_10118286 0.553


chr19_+_17420352 0.553 DDA1
DET1 and DDB1 associated 1
chr14_-_23388380 0.552 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr8_-_130951896 0.550 FAM49B
family with sequence similarity 49, member B
chr2_-_230786618 0.550 NM_004238
TRIP12
thyroid hormone receptor interactor 12
chr13_-_31191509 0.547 HMGB1
high mobility group box 1
chr11_+_61560108 0.546 NM_004111
FEN1
flap structure-specific endonuclease 1
chr1_-_183604793 0.546 ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr1_+_169337193 0.545 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr11_+_61560401 0.538 FEN1
flap structure-specific endonuclease 1
chr15_+_101420032 0.535 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr11_-_65655837 0.532 NM_004214
NM_198897
FIBP

fibroblast growth factor (acidic) intracellular binding protein

chr10_+_12237929 0.530 NM_006023
CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr15_+_41136622 0.529 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr18_-_53068755 0.526 TCF4
transcription factor 4
chrX_-_15872905 0.517


chr7_-_99698278 0.515 NM_182776
MCM7
minichromosome maintenance complex component 7
chr17_+_40985425 0.508 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr12_-_54653369 0.508 NM_001127321
CBX5
chromobox homolog 5
chr10_+_17271302 0.506 VIM
vimentin
chr10_+_17271276 0.506 VIM
vimentin
chr5_+_34656595 0.506 NM_001145520
RAI14
retinoic acid induced 14
chr7_+_143078395 0.504 ZYX
zyxin
chr10_+_17271277 0.504 VIM
vimentin
chr15_+_66161769 0.499 NM_001206836
NM_004663
RAB11A

RAB11A, member RAS oncogene family

chr10_+_17271341 0.499 VIM
vimentin
chr2_-_190044330 0.498 NM_000393
COL5A2
collagen, type V, alpha 2
chr11_+_35160666 0.497 CD44
CD44 molecule (Indian blood group)
chr5_-_171615095 0.497 STK10
serine/threonine kinase 10
chr1_-_183604885 0.496 NM_005717
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr10_+_26986557 0.494 NM_014317
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr11_+_86013252 0.494 NM_016401
C11orf73
chromosome 11 open reading frame 73
chr1_-_226926875 0.492 NM_002221
ITPKB
inositol-trisphosphate 3-kinase B
chr7_+_143078447 0.490 ZYX
zyxin
chr5_-_151066492 0.487 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr10_+_17270469 0.484 VIM
vimentin
chr1_-_161102457 0.482 NM_001039711
NM_032998
DEDD

death effector domain containing

chr10_-_111683245 0.481 NM_001167604
NM_020383
XPNPEP1

X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

chr2_+_237478379 0.481 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr22_+_39077960 0.478 TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr5_+_34656367 0.477 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr11_+_128563772 0.476 NM_001167681
NM_002017
FLI1

Friend leukemia virus integration 1

chr1_+_110091218 0.475 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chrX_+_48542159 0.474 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr8_-_6420454 0.474 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr22_+_39077979 0.471 TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr10_-_51623214 0.471 NM_006327
TIMM23
translocase of inner mitochondrial membrane 23 homolog (yeast)
chr22_+_39077975 0.471 TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr7_+_143078457 0.467 ZYX
zyxin
chr11_-_414975 0.465 NM_001135054
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr15_-_83736105 0.464 NM_001011885
NM_025238
BTBD1

BTB (POZ) domain containing 1

chr4_+_103422479 0.462 NM_001165412
NM_003998
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr7_+_143078444 0.458 ZYX
zyxin
chrX_-_15872921 0.457 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr9_-_132586363 0.457 TOR1A
torsin family 1, member A (torsin A)
chr1_+_84609941 0.456 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_+_143078399 0.455 ZYX
zyxin
chr1_-_43637788 0.454 EBNA1BP2
EBNA1 binding protein 2
chr3_-_119396220 0.453 NM_005694
COX17
COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr5_+_140071141 0.453 HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr4_-_10118460 0.453 WDR1
WD repeat domain 1
chr17_-_46687925 0.452 HOXB7
homeobox B7
chr11_+_128563973 0.451 FLI1
Friend leukemia virus integration 1
chr3_-_69062744 0.451 NM_173654
C3orf64
chromosome 3 open reading frame 64
chr15_-_93198602 0.450 NM_207446
FAM174B
family with sequence similarity 174, member B
chr3_-_49449525 0.449 NM_001664
RHOA
ras homolog gene family, member A
chr9_+_127631476 0.448 NM_030978
ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr9_+_116356199 0.444 NM_144489
RGS3
regulator of G-protein signaling 3
chr2_+_201676659 0.443 BZW1
basic leucine zipper and W2 domains 1
chrX_+_49028183 0.443 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chrX_-_10851808 0.441 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr22_+_39077953 0.441 NM_020243
TOMM22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr5_+_17217474 0.440 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr3_-_49449393 0.439 RHOA
ras homolog gene family, member A
chr3_-_64009094 0.439 NM_014814
PSMD6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr1_+_110091249 0.439 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr4_+_56719808 0.438 NM_001024924
NM_018261
NM_178237
EXOC1


exocyst complex component 1


chr9_+_116356407 0.435 RGS3
regulator of G-protein signaling 3
chr1_-_85741992 0.435 BCL10
B-cell CLL/lymphoma 10
chr8_-_144911535 0.434 NM_014281
NM_078480
PUF60

poly-U binding splicing factor 60KDa

chr3_-_171177851 0.432 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr17_+_32582295 0.432 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr4_-_10118444 0.431 WDR1
WD repeat domain 1
chr4_+_103422822 0.430 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_+_26485510 0.430 NM_024869
FAM110D
family with sequence similarity 110, member D
chr3_+_119316694 0.430 NM_001206960
NM_001206961
NM_015900
PLA1A


phospholipase A1 member A


chr6_-_44233244 0.429 NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr8_-_144911174 0.428 NM_001136033
PUF60
poly-U binding splicing factor 60KDa
chr19_+_35168558 0.428 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr1_-_43637958 0.428 EBNA1BP2
EBNA1 binding protein 2
chr10_+_70847817 0.427 NM_002727
SRGN
serglycin
chr19_-_51456159 0.426 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr1_-_156698188 0.424 ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr14_+_50087400 0.423 NM_002408
MGAT2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr3_+_14220343 0.423 LSM3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr9_-_27529434 0.423 NM_024761
MOB3B
MOB kinase activator 3B
chr3_+_48507209 0.423 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr13_-_46756295 0.423 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_+_128563993 0.422 FLI1
Friend leukemia virus integration 1
chr3_-_32544319 0.422 CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr3_+_184032849 0.422 NM_182917
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr11_+_32112414 0.421 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
766.64 5.83e-05 GO:0005945 6-phosphofructokinase complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
766.64 4.11e-05 GO:0003872 6-phosphofructokinase activity
328.61 2.87e-04 GO:0008443 phosphofructokinase activity
127.85 2.08e-03 GO:0019200 carbohydrate kinase activity