Motif ID: FEV.p2

Z-value: 1.248


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FEVchr2_-_219850273-0.136.3e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_121379757 2.953 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_121379701 2.796 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_-_39826625 2.011 GMFG
glia maturation factor, gamma
chr2_+_33661392 1.959 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr8_-_82395401 1.825 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr19_-_39826676 1.814 NM_004877
GMFG
glia maturation factor, gamma
chr18_-_53177999 1.631 NM_001243231
TCF4
transcription factor 4
chr17_-_62084282 1.589 NM_000873
ICAM2
intercellular adhesion molecule 2
chr4_-_101439071 1.404 NM_001159694
NM_016242
EMCN

endomucin

chr12_-_6233684 1.376 NM_000552
VWF
von Willebrand factor
chr1_-_79472360 1.267 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr5_-_54281345 1.194 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr21_-_15918635 1.121 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr2_-_175499275 1.029 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr8_+_74903563 1.020 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr9_+_116356199 0.961 NM_144489
RGS3
regulator of G-protein signaling 3
chr4_+_90816002 0.927 NM_007351
MMRN1
multimerin 1
chr16_+_1583657 0.915 TMEM204
transmembrane protein 204
chr17_-_34417386 0.898 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr11_-_33891485 0.892 NM_001142315
LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_-_76381787 0.890 NM_001128922
LRRC32
leucine rich repeat containing 32
chr17_-_62097937 0.869 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr14_-_23285011 0.818 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr4_+_40198526 0.815 NM_004310
RHOH
ras homolog gene family, member H
chr10_+_31610063 0.803 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr10_-_98031154 0.800 NM_001114094
NM_013314
BLNK

B-cell linker

chr17_+_67410825 0.779 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr20_+_44746889 0.769 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr17_-_29641094 0.754 NM_006495
EVI2B
ecotropic viral integration site 2B
chr21_-_39870303 0.748 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr13_-_46756326 0.746 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_-_33891361 0.742 NM_001142316
LMO2
LIM domain only 2 (rhombotin-like 1)
chr9_-_130617009 0.733 NM_000118
NM_001114753
ENG

endoglin

chr11_+_22688156 0.730 NM_001143830
GAS2
growth arrest-specific 2
chr1_+_111415791 0.723 CD53
CD53 molecule
chrY_+_2709630 0.717 RPS4Y1
ribosomal protein S4, Y-linked 1
chr6_-_32160289 0.715 GPSM3
G-protein signaling modulator 3
chrY_+_2709596 0.715 NM_001008
RPS4Y1
ribosomal protein S4, Y-linked 1
chr13_-_46756295 0.714 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_-_38721701 0.710 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr11_-_111249902 0.709 POU2AF1
POU class 2 associating factor 1
chr6_-_11382501 0.706 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr1_+_111415721 0.706 NM_000560
CD53
CD53 molecule
chr7_-_150329735 0.703 NM_001244071
NM_001244072
NM_024711
GIMAP6


GTPase, IMAP family member 6


chr11_-_33891258 0.691 LMO2
LIM domain only 2 (rhombotin-like 1)
chr9_-_130616957 0.686 ENG
endoglin
chr1_+_43766565 0.686 NM_001253357
NM_005424
TIE1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

chr11_-_111250156 0.677 NM_006235
POU2AF1
POU class 2 associating factor 1
chr1_+_198608216 0.671 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_-_150738255 0.650 CTSS
cathepsin S
chr17_-_29641087 0.646 EVI2B
ecotropic viral integration site 2B
chr9_-_130616760 0.642 ENG
endoglin
chr1_-_183559669 0.635 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr13_+_111806038 0.634 NM_003899
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr8_+_40010986 0.626 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr15_-_93198602 0.621 NM_207446
FAM174B
family with sequence similarity 174, member B
chr6_+_153019029 0.620 NM_025107
MYCT1
myc target 1
chr1_-_150738232 0.620 CTSS
cathepsin S
chr1_+_198608136 0.611 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr9_+_116356407 0.593 RGS3
regulator of G-protein signaling 3
chr11_-_104034685 0.593 PDGFD
platelet derived growth factor D
chr7_+_93551015 0.591 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr22_-_19512859 0.583 NM_001130861
NM_003277
CLDN5

claudin 5

chr11_-_33890931 0.576 LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_-_53601051 0.576 ITGB7
integrin, beta 7
chr17_-_29641068 0.567 EVI2B
ecotropic viral integration site 2B
chrX_+_12885190 0.566 NM_016562
TLR7
toll-like receptor 7
chr11_-_104035023 0.562 NM_025208
NM_033135
PDGFD

platelet derived growth factor D

chr13_+_111806070 0.558 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr11_+_61129831 0.555 TMEM138
transmembrane protein 138
chr1_-_111743297 0.551 DENND2D
DENN/MADD domain containing 2D
chrX_+_128913881 0.541 NM_018990
SASH3
SAM and SH3 domain containing 3
chr7_+_150264457 0.539 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr14_-_77923888 0.533 NM_001193314
NM_001193315
NM_001193316
NM_001193317
NM_022067
C14orf133




chromosome 14 open reading frame 133




chr12_+_12938540 0.532 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr1_+_212738675 0.527 NM_001030287
ATF3
activating transcription factor 3
chr1_+_183774214 0.518 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr14_+_21249209 0.514 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr22_-_37640287 0.512 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr17_+_32582295 0.505 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chrX_+_128913897 0.505 SASH3
SAM and SH3 domain containing 3
chr1_-_183560010 0.497 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr3_+_113251217 0.488 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr10_+_70847857 0.486 SRGN
serglycin
chr6_-_154677868 0.484 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr12_-_53600999 0.484 NM_000889
ITGB7
integrin, beta 7
chr16_+_66400524 0.481 NM_001795
CDH5
cadherin 5, type 2 (vascular endothelium)
chr1_-_31230673 0.480 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr10_+_70847817 0.480 NM_002727
SRGN
serglycin
chr15_+_81589240 0.477 NM_004513
IL16
interleukin 16
chr3_-_171528227 0.475 NM_001130081
NM_002662
PLD1

phospholipase D1, phosphatidylcholine-specific

chr15_-_80263460 0.475 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr3_+_52529351 0.475 NM_015136
STAB1
stabilin 1
chr19_+_49838673 0.475 NM_001040031
NM_001774
CD37

CD37 molecule

chr2_-_136873740 0.471 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr11_+_102188180 0.470 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr12_-_92539614 0.466 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr17_-_34313685 0.463 NM_032962
NM_032963
CCL14

chemokine (C-C motif) ligand 14

chr13_-_29069215 0.462 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr15_-_37392322 0.461 MEIS2
Meis homeobox 2
chr5_-_88178964 0.459 MEF2C
myocyte enhancer factor 2C
chr13_-_46756291 0.454 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chrX_-_15872938 0.454 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr20_+_44746948 0.453 CD40
CD40 molecule, TNF receptor superfamily member 5
chr5_-_88199868 0.453 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr3_-_46249787 0.450 NM_001295
CCR1
chemokine (C-C motif) receptor 1
chr5_+_133984234 0.448 NM_001252231
NM_021982
SEC24A

SEC24 family, member A (S. cerevisiae)

chr9_-_130616592 0.447 ENG
endoglin
chr22_+_23165273 0.445


chrX_-_15872882 0.444 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr1_-_111743261 0.440 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr12_-_6798419 0.434 ZNF384
zinc finger protein 384
chr1_-_150669499 0.432 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr16_+_77225107 0.431 MON1B
MON1 homolog B (yeast)
chr12_-_15114495 0.431 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr14_+_100531745 0.430 NM_016337
EVL
Enah/Vasp-like
chr9_+_116327301 0.430 NM_134427
RGS3
regulator of G-protein signaling 3
chr1_+_198608244 0.429 PTPRC
protein tyrosine phosphatase, receptor type, C
chr11_-_104035065 0.428 PDGFD
platelet derived growth factor D
chr22_-_37640187 0.420 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr2_+_143886898 0.419 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr9_+_77703412 0.418 OSTF1
osteoclast stimulating factor 1
chr1_+_82266081 0.412 NM_012302
LPHN2
latrophilin 2
chr2_-_99279935 0.410 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr20_-_23066828 0.410 NM_012072
CD93
CD93 molecule
chr19_+_49838700 0.404 CD37
CD37 molecule
chr12_-_10251520 0.404 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr1_+_150245182 0.401 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr4_-_5021095 0.401 NM_018659
CYTL1
cytokine-like 1
chr22_+_37257004 0.400 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr19_-_36236291 0.400 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr1_-_183559463 0.398 NCF2
neutrophil cytosolic factor 2
chr11_-_3862137 0.396 RHOG
ras homolog gene family, member G (rho G)
chr12_+_25205180 0.396 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr1_+_158801105 0.394 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr2_+_143886969 0.393 ARHGAP15
Rho GTPase activating protein 15
chr3_+_48507209 0.392 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr16_-_88717395 0.392 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr4_-_16900348 0.391 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr18_+_32621299 0.390 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr3_+_52529370 0.389 STAB1
stabilin 1
chr2_+_37571752 0.387 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr2_-_64371444 0.386 NM_020651
PELI1
pellino homolog 1 (Drosophila)
chr10_+_114133775 0.378 ACSL5
acyl-CoA synthetase long-chain family member 5
chr5_+_95066628 0.378 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chrX_-_15872921 0.378 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr11_+_60223281 0.377 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr1_-_150738292 0.377 NM_001199739
NM_004079
CTSS

cathepsin S

chr2_-_110371669 0.376 NM_144710
NM_178584
SEPT10

septin 10

chr6_+_107811272 0.374 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr19_+_49838646 0.373 CD37
CD37 molecule
chr19_+_14551087 0.373 PKN1
protein kinase N1
chr11_+_64863607 0.368 NM_013265
C11orf2
chromosome 11 open reading frame 2
chr6_-_31550065 0.367 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr1_-_173174611 0.367 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr11_+_64863711 0.366 C11orf2
chromosome 11 open reading frame 2
chr3_-_53381533 0.366 NM_018403
DCP1A
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr11_+_64863700 0.365 C11orf2
chromosome 11 open reading frame 2
chr14_-_107179043 0.364 IGHA1
immunoglobulin heavy constant alpha 1
chr2_-_225266710 0.362 NM_001122779
NM_024785
FAM124B

family with sequence similarity 124B

chr1_-_31230594 0.360 LAPTM5
lysosomal protein transmembrane 5
chr4_-_16900256 0.358 LDB2
LIM domain binding 2
chr14_-_23284617 0.357 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr4_+_103422479 0.355 NM_001165412
NM_003998
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr14_-_54421269 0.355 NM_130851
BMP4
bone morphogenetic protein 4
chr13_+_58205943 0.354 PCDH17
protocadherin 17
chr17_-_16875388 0.350 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr11_-_89224413 0.350 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr17_-_56595192 0.349 NM_004687
MTMR4
myotubularin related protein 4
chr4_+_103422822 0.349 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr19_-_51875790 0.348 NM_005601
NKG7
natural killer cell group 7 sequence
chr17_-_79269082 0.347 NM_001037984
NM_138570
SLC38A10

solute carrier family 38, member 10

chr16_+_77224827 0.343 NM_014940
MON1B
MON1 homolog B (yeast)
chr8_+_38585703 0.342 NM_001146216
TACC1
transforming, acidic coiled-coil containing protein 1
chr13_+_31191829 0.342 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr10_+_114133838 0.340 NM_203379
ACSL5
acyl-CoA synthetase long-chain family member 5
chrX_-_15872905 0.340


chr4_-_16900028 0.339 LDB2
LIM domain binding 2
chr19_-_6481765 0.337 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr7_-_135662194 0.336 NM_145808
NM_001128619
MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr7_-_115670828 0.334 NM_001018058
NM_012252
TFEC

transcription factor EC

chr7_-_115670774 0.333 TFEC
transcription factor EC
chr1_-_163172624 0.331 NM_001195303
RGS5
regulator of G-protein signaling 5
chr7_-_1595746 0.331 NM_001097620
TMEM184A
transmembrane protein 184A
chr2_-_174829951 0.331 SP3
Sp3 transcription factor
chr22_-_37545944 0.330 NM_000878
IL2RB
interleukin 2 receptor, beta
chr20_+_35201948 0.329 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr14_-_55658205 0.328 NM_001146015
NM_014750
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr21_-_46340874 0.327 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr7_-_37488408 0.326 ELMO1
engulfment and cell motility 1
chr12_+_25205488 0.322 LRMP
lymphoid-restricted membrane protein
chr18_-_60986508 0.320 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr16_-_24942662 0.319 ARHGAP17
Rho GTPase activating protein 17
chr2_+_118846029 0.315 NM_016133
INSIG2
insulin induced gene 2
chr17_+_18380097 0.314 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr22_+_23134980 0.313


chr1_-_207095198 0.312 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr4_+_8200918 0.310 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr19_-_10450262 0.309 NM_002162
ICAM3
intercellular adhesion molecule 3
chr11_+_128563973 0.309 FLI1
Friend leukemia virus integration 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.