Motif ID: GGCAGUG

Z-value: 1.121


Mature miRNA associated with seed GGCAGUG:

NamemiRBase Accession
hsa-miR-34a MIMAT0000255
hsa-miR-34c-5p MIMAT0000686
hsa-miR-449a MIMAT0001541
hsa-miR-449b MIMAT0003327



Activity profile for motif GGCAGUG.

activity profile for motif GGCAGUG


Sorted Z-values histogram for motif GGCAGUG

Sorted Z-values for motif GGCAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of GGCAGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_80993009 2.423 NM_001025252
TPD52
tumor protein D52
chr8_-_81083660 2.036 NM_001025253
NM_005079
TPD52

tumor protein D52

chr6_+_21593963 1.220 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr2_-_99279935 1.170 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr20_-_10654429 1.148 NM_000214
JAG1
jagged 1
chr18_+_55714457 1.130 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr1_+_64059479 1.062 NM_001172819
PGM1
phosphoglucomutase 1
chr1_+_64058891 1.010 NM_002633
PGM1
phosphoglucomutase 1
chr19_-_41196419 1.010 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr18_+_55862577 1.001 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr18_+_55816546 0.966 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr1_+_64088886 0.960 NM_001172818
PGM1
phosphoglucomutase 1
chr12_-_95611023 0.956 NM_018351
FGD6
FYVE, RhoGEF and PH domain containing 6
chr18_+_55888750 0.932 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr3_-_56835829 0.926 NM_019555
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr2_+_169312793 0.908 NM_203463
CERS6
ceramide synthase 6
chr3_-_56809594 0.908 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr10_-_116286661 0.900 NM_006720
ABLIM1
actin binding LIM protein 1
chr2_-_99347588 0.899 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr18_+_55711388 0.885 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chr15_-_61521478 0.878 NM_134261
RORA
RAR-related orphan receptor A
chr3_-_57113292 0.873 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr10_-_116444374 0.865 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr8_-_134309448 0.863 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr10_-_116418056 0.855 NM_002313
ABLIM1
actin binding LIM protein 1
chr16_-_4588379 0.847 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr14_+_59655351 0.841 NM_014992
DAAM1
dishevelled associated activator of morphogenesis 1
chr7_-_139876718 0.834 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr16_-_4588738 0.833 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr17_+_1646129 0.829 NM_000934
NM_001165921
SERPINF2

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

chr17_+_1646290 0.825 NM_001165920
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr11_-_27494232 0.817 NM_018490
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chrX_+_105937067 0.775 NM_024539
RNF128
ring finger protein 128
chr15_-_60884615 0.769 NM_134262
RORA
RAR-related orphan receptor A
chr18_-_48724031 0.759 NM_016626
MEX3C
mex-3 homolog C (C. elegans)
chr14_-_99737821 0.753 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr5_-_150948504 0.742 NM_001447
FAT2
FAT tumor suppressor homolog 2 (Drosophila)
chr7_+_94285676 0.740 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chrX_+_105969875 0.701 NM_194463
RNF128
ring finger protein 128
chr20_+_37434294 0.687 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr7_+_116312412 0.666 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr18_-_28622624 0.663 NM_001941
NM_024423
DSC3

desmocollin 3

chr5_-_175964223 0.639 NM_014901
RNF44
ring finger protein 44
chr14_-_75422466 0.636 NM_001207012
NM_002632
PGF

placental growth factor

chr7_+_94285620 0.625 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr6_+_36098261 0.625 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr15_-_60919642 0.624 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr8_+_102504661 0.618 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr7_-_44924946 0.613 NM_033224
PURB
purine-rich element binding protein B
chr11_+_92085261 0.525 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr16_+_22217369 0.524 NM_013302
EEF2K
eukaryotic elongation factor-2 kinase
chr8_-_17579729 0.522 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr5_+_49962771 0.519 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr7_-_73133917 0.518 NM_001165903
NM_004603
STX1A

syntaxin 1A (brain)

chr5_-_94417544 0.506 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr17_+_26646120 0.505 NM_014573
TMEM97
transmembrane protein 97
chr12_-_56652118 0.502 NM_173595
ANKRD52
ankyrin repeat domain 52
chr2_+_24272583 0.498 NM_004116
NM_054033
FKBP1B

FK506 binding protein 1B, 12.6 kDa

chr5_-_94620277 0.485 NM_024717
MCTP1
multiple C2 domains, transmembrane 1
chr8_-_17580024 0.483 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr14_-_89883306 0.477 NM_005197
FOXN3
forkhead box N3
chr8_-_17555158 0.472 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr5_+_49961732 0.470 NM_001178055
PARP8
poly (ADP-ribose) polymerase family, member 8
chr12_+_1100352 0.470 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chr4_+_75480628 0.465 NM_001657
AREG
amphiregulin
chr20_+_35201948 0.464 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr4_+_75310852 0.462 NM_001657
AREG
amphiregulin
chr8_-_17658385 0.459 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr3_+_171758289 0.456 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr6_-_6007632 0.423 NM_016588
NRN1
neuritin 1
chr20_+_35201854 0.420 NM_001199513
NM_001199514
TGIF2

TGFB-induced factor homeobox 2

chr1_-_151431892 0.419 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chrX_-_110655384 0.418 NM_178151
NM_001195553
NM_178152
NM_178153
DCX



doublecortin



chr2_-_73496595 0.411 NM_001080410
FBXO41
F-box protein 41
chr22_-_38902344 0.407 NM_001098504
NM_006386
DDX17

DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

chr2_-_166930130 0.402 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr5_-_95297597 0.396 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr1_+_66458389 0.389 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr12_-_52914080 0.386 NM_000424
KRT5
keratin 5
chr3_-_53381533 0.384 NM_018403
DCP1A
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr2_-_167005641 0.381 NM_001202435
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr7_+_128864740 0.379 NM_001130720
NM_015328
AHCYL2

adenosylhomocysteinase-like 2

chrX_+_9983793 0.369 NM_015691
WWC3
WWC family member 3
chr11_+_3829765 0.368 NM_014489
PGAP2
post-GPI attachment to proteins 2
chr2_+_203499819 0.368 NM_173511
FAM117B
family with sequence similarity 117, member B
chr10_+_8096633 0.364 NM_001002295
NM_002051
GATA3

GATA binding protein 3

chr1_+_66797775 0.362 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr18_-_74844762 0.359 NM_001025100
NM_001025101
MBP

myelin basic protein

chr18_+_55102777 0.359 NM_004852
ONECUT2
one cut homeobox 2
chr2_-_122042767 0.358 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr12_+_27397077 0.355 NM_015000
STK38L
serine/threonine kinase 38 like
chr3_+_39851028 0.350 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr12_-_57030083 0.349 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr8_+_28174648 0.348 NM_006228
PNOC
prepronociceptin
chrX_-_110654373 0.348 NM_000555
DCX
doublecortin
chr3_+_171757413 0.347 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr2_-_20424627 0.345 NM_002997
SDC1
syndecan 1
chr22_-_36784055 0.342 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr3_+_38495778 0.342 NM_001106
ACVR2B
activin A receptor, type IIB
chr2_-_20425166 0.340 NM_001006946
SDC1
syndecan 1
chr9_-_139440237 0.333 NM_017617
NOTCH1
notch 1
chr2_+_74881353 0.328 NM_004263
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr3_+_63884074 0.328 NM_001177387
ATXN7
ataxin 7
chr3_+_105085553 0.323 NM_001243280
NM_001243281
NM_001243283
NM_001627
ALCAM



activated leukocyte cell adhesion molecule



chr17_+_70117154 0.322 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr14_-_95786095 0.320 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr11_+_3818953 0.320 NM_001145438
PGAP2
post-GPI attachment to proteins 2
chr6_-_90121966 0.319 NM_021244
RRAGD
Ras-related GTP binding D
chr3_-_49314281 0.319 NM_198562
C3orf62
chromosome 3 open reading frame 62
chr9_-_5833072 0.315 NM_024896
ERMP1
endoplasmic reticulum metallopeptidase 1
chr12_+_65218351 0.311 NM_015279
TBC1D30
TBC1 domain family, member 30
chr14_-_94856926 0.308 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr8_+_123793894 0.305 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr22_-_37545944 0.305 NM_000878
IL2RB
interleukin 2 receptor, beta
chr12_-_52967608 0.305 NM_175053
KRT74
keratin 74
chr10_-_105677986 0.303 NM_024928
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr1_+_66258855 0.299 NM_002600
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_-_196695608 0.298 NM_025163
PIGZ
phosphatidylinositol glycan anchor biosynthesis, class Z
chr3_+_113251217 0.296 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr1_+_66258192 0.296 NM_001037341
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_-_147232684 0.295 NM_181703
GJA5
gap junction protein, alpha 5, 40kDa
chr1_-_147245483 0.294 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr12_+_109535922 0.291 NM_003362
UNG
uracil-DNA glycosylase
chr10_+_82213892 0.288 NM_001128309
NM_030927
TSPAN14

tetraspanin 14

chr5_-_1524022 0.284 NM_024830
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr7_+_145813452 0.284 NM_014141
CNTNAP2
contactin associated protein-like 2
chr14_+_71374111 0.283 NM_014982
PCNX
pecanex homolog (Drosophila)
chr12_+_1800188 0.283 NM_024551
ADIPOR2
adiponectin receptor 2
chr12_+_109535377 0.283 NM_080911
UNG
uracil-DNA glycosylase
chr17_+_2240795 0.282 NM_014853
NM_001098509
SGSM2

small G protein signaling modulator 2

chr7_-_22396511 0.281 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr8_+_42752019 0.281 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr5_+_133861685 0.277 NM_015288
PHF15
PHD finger protein 15
chr9_-_100935173 0.274 NM_003389
CORO2A
coronin, actin binding protein, 2A
chr11_+_57529233 0.267 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001206883
NM_001206884
NM_001206885
NM_001206886
NM_001206887
NM_001206888
NM_001206889
NM_001206890
NM_001206891
NM_001331
CTNND1





















catenin (cadherin-associated protein), delta 1





















chr9_-_100954883 0.267 NM_052820
CORO2A
coronin, actin binding protein, 2A
chr7_+_138916230 0.264 NM_173569
UBN2
ubinuclein 2
chr1_+_20915440 0.261 NM_001785
CDA
cytidine deaminase
chr7_+_100770378 0.260 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chrX_+_24483343 0.259 NM_001142386
NM_005391
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chr17_+_12692779 0.259 NM_014859
ARHGAP44
Rho GTPase activating protein 44
chr7_+_2443164 0.258 NM_001243794
NM_001243795
NM_018641
CHST12


carbohydrate (chondroitin 4) sulfotransferase 12


chr14_-_94855120 0.257 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr5_-_132299263 0.253 NM_014423
AFF4
AF4/FMR2 family, member 4
chr17_+_46125675 0.252 NM_003204
NFE2L1
nuclear factor (erythroid-derived 2)-like 1
chr13_+_28712379 0.250 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr20_+_35974458 0.247 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr11_+_107461807 0.245 NM_001130037
NM_018712
ELMOD1

ELMO/CED-12 domain containing 1

chr10_+_112631552 0.245 NM_001199492
NM_014456
NM_145341
PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr11_+_64126616 0.243 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chr7_+_129015483 0.243 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr5_-_159739482 0.243 NM_024565
CCNJL
cyclin J-like
chr9_+_115913227 0.237 NM_001860
SLC31A2
solute carrier family 31 (copper transporters), member 2
chr1_-_151414641 0.237 NM_207171
POGZ
pogo transposable element with ZNF domain
chr2_+_113885137 0.236 NM_173842
IL1RN
interleukin 1 receptor antagonist
chrX_+_109246338 0.236 NM_032227
TMEM164
transmembrane protein 164
chr19_+_54372659 0.235 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr12_-_123380682 0.235 NM_024667
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr14_+_24584467 0.232 NM_181357
DCAF11
DDB1 and CUL4 associated factor 11
chr2_-_27485774 0.231 NM_003459
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr1_+_167298280 0.231 NM_001198783
POU2F1
POU class 2 homeobox 1
chr3_-_27498244 0.229 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr10_+_97515408 0.228 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr1_-_41131323 0.228 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr14_+_24583979 0.228 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr17_-_71640226 0.226 NM_001144952
SDK2
sidekick cell adhesion molecule 2
chr17_-_1012257 0.226 NM_001092
ABR
active BCR-related gene
chr1_+_53192021 0.225 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr1_+_167189948 0.223 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr7_+_129007942 0.223 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr5_-_138211054 0.223 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr20_+_32951054 0.222 NM_031483
ITCH
itchy E3 ubiquitin protein ligase homolog (mouse)
chr14_+_24583905 0.221 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chrX_+_152990322 0.221 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr20_+_35973083 0.221 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr6_-_16761600 0.221 NM_000332
NM_001128164
ATXN1

ataxin 1

chr19_-_46295785 0.219 NM_004943
DMWD
dystrophia myotonica, WD repeat containing
chr17_+_43971655 0.218 NM_001123066
NM_001123067
NM_001203251
NM_001203252
NM_005910
NM_016834
NM_016835
NM_016841
MAPT







microtubule-associated protein tau







chr17_+_61627818 0.218 NM_005828
DCAF7
DDB1 and CUL4 associated factor 7
chr20_+_5107393 0.218 NM_003818
CDS2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr16_-_67840464 0.217 NM_020850
RANBP10
RAN binding protein 10
chr8_-_57123858 0.217 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr19_-_43969723 0.217 NM_014400
LYPD3
LY6/PLAUR domain containing 3
chr19_-_2456954 0.212 NM_032737
LMNB2
lamin B2
chr2_+_26915390 0.212 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr8_-_82024277 0.208 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr9_+_112810877 0.207 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chrX_+_68048792 0.205 NM_004429
EFNB1
ephrin-B1
chr14_+_20937537 0.205 NM_000270
PNP
purine nucleoside phosphorylase
chr3_+_63953419 0.204 NM_001128149
ATXN7
ataxin 7
chr2_+_102314162 0.202 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr1_-_21995793 0.202 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr15_-_52861177 0.202 NM_006628
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr2_+_45169036 0.200 NM_005413
SIX3
SIX homeobox 3
chr1_-_207205996 0.198 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr14_-_68162419 0.195 NM_001252650
NM_016026
RDH11

retinol dehydrogenase 11 (all-trans/9-cis/11-cis)

chr22_-_29977075 0.195 NM_001202502
NIPSNAP1
nipsnap homolog 1 (C. elegans)
chr10_-_62149487 0.194 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_+_124768401 0.191 NM_001609
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr14_-_35873823 0.191 NM_020529
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
18.95 2.40e-02 GO:0002520 immune system development

Nothing significant found in compartment category.

Nothing significant found in function category.