Motif ID: GUCAGUU

Z-value: 0.710


Mature miRNA associated with seed GUCAGUU:

NamemiRBase Accession
hsa-miR-223 MIMAT0000280



Activity profile for motif GUCAGUU.

activity profile for motif GUCAGUU


Sorted Z-values histogram for motif GUCAGUU

Sorted Z-values for motif GUCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of GUCAGUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_99801365 1.006 NM_001333
CTSL2
cathepsin L2
chr9_-_99801924 0.977 NM_001201575
CTSL2
cathepsin L2
chr4_+_47487230 0.786 NM_020453
ATP10D
ATPase, class V, type 10D
chr8_-_67525426 0.712 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

uncharacterized LOC645895
chrX_-_13956644 0.684 NM_001001994
GPM6B
glycoprotein M6B
chr3_-_149688638 0.651 NM_002628
NM_053024
PFN2

profilin 2

chr12_-_90049818 0.553 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr2_+_5832778 0.538 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr5_+_86564044 0.537 NM_002890
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chrX_-_13835313 0.525 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr17_+_48133331 0.519 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr5_+_86564727 0.515 NM_022650
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr2_-_110371669 0.505 NM_144710
NM_178584
SEPT10

septin 10

chr11_-_58343308 0.473 NM_004811
LPXN
leupaxin
chr11_-_58345593 0.472 NM_001143995
LPXN
leupaxin
chr12_-_31743822 0.460 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr2_-_158300517 0.448 NM_004288
CYTIP
cytohesin 1 interacting protein
chr5_+_125758818 0.432 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr5_+_125800786 0.429 NM_001146322
GRAMD3
GRAM domain containing 3
chr14_+_67707825 0.414 NM_022474
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr5_+_125695787 0.402 NM_001146319
GRAMD3
GRAM domain containing 3
chr16_+_50321822 0.401 NM_001114
ADCY7
adenylate cyclase 7
chr4_-_153456152 0.396 NM_033632
FBXW7
F-box and WD repeat domain containing 7
chr10_+_74033676 0.386 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr2_-_264037 0.386 NM_001159597
NM_015677
SH3YL1

SH3 domain containing, Ysc84-like 1 (S. cerevisiae)

chr9_+_112887780 0.385 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr9_+_112810877 0.378 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr5_-_88199868 0.373 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr4_-_153273683 0.371 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr16_-_87903028 0.367 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chrX_+_100805415 0.352 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr5_-_88179278 0.348 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr4_-_153303663 0.338 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chrX_+_135251454 0.335 NM_001159704
FHL1
four and a half LIM domains 1
chrX_+_135251795 0.326 NM_001167819
FHL1
four and a half LIM domains 1
chr2_-_86565205 0.326 NM_001164730
REEP1
receptor accessory protein 1
chrX_+_135278912 0.326 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr3_+_138066489 0.325 NM_001252091
NM_012219
MRAS

muscle RAS oncogene homolog

chr10_-_79397546 0.325 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr21_-_19191643 0.320 NM_001100420
NM_001100421
NM_017447
C21orf91


chromosome 21 open reading frame 91


chr2_+_192109879 0.313 NM_001130158
NM_012223
NM_001161819
MYO1B


myosin IB


chr13_-_46961634 0.311 NM_025113
KIAA0226L
KIAA0226-like
chr4_+_85504056 0.308 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr11_-_14380030 0.307 NM_001177315
NM_001102669
RRAS2

related RAS viral (r-ras) oncogene homolog 2

chrX_-_34675366 0.304 NM_031442
TMEM47
transmembrane protein 47
chr2_-_86564632 0.299 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr11_-_14380591 0.298 NM_012250
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr11_-_14386051 0.292 NM_001177314
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr12_+_4430346 0.292 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr4_-_187644983 0.291 NM_005245
FAT1
FAT tumor suppressor homolog 1 (Drosophila)
chr13_-_77460432 0.291 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr4_+_174089889 0.288 NM_017423
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr1_-_221910801 0.283 NM_144728
DUSP10
dual specificity phosphatase 10
chr12_-_21654484 0.271 NM_002907
NM_032941
RECQL

RecQ protein-like (DNA helicase Q1-like)

chr1_-_221915458 0.269 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chrX_+_135230736 0.269 NM_001159700
FHL1
four and a half LIM domains 1
chrX_+_135229536 0.266 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr5_-_95297597 0.265 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr2_-_227663454 0.265 NM_005544
IRS1
insulin receptor substrate 1
chr13_-_110438896 0.262 NM_003749
IRS2
insulin receptor substrate 2
chr22_-_30642683 0.262 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr3_-_87040246 0.258 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr1_-_95007139 0.252 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr18_+_42260774 0.252 NM_015559
SETBP1
SET binding protein 1
chrX_-_100914816 0.250 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr12_+_79439432 0.249 NM_001135806
SYT1
synaptotagmin I
chr17_+_76183397 0.245 NM_001010982
NM_001145526
AFMID

arylformamidase

chr12_+_79257772 0.244 NM_001135805
SYT1
synaptotagmin I
chr5_-_88119604 0.239 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr10_+_54074037 0.239 NM_012242
DKK1
dickkopf 1 homolog (Xenopus laevis)
chr1_+_192544856 0.236 NM_002922
RGS1
regulator of G-protein signaling 1
chr16_+_56659584 0.232 NM_175617
MT1E
metallothionein 1E
chr3_+_147127151 0.232 NM_003412
ZIC1
Zic family member 1
chr9_+_112542496 0.230 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr3_+_158991035 0.229 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr3_-_9291251 0.228 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chrX_+_128913881 0.225 NM_018990
SASH3
SAM and SH3 domain containing 3
chr12_+_79258448 0.223 NM_005639
SYT1
synaptotagmin I
chr2_+_241375030 0.222 NM_002081
GPC1
glypican 1
chr1_-_46598250 0.222 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr12_-_54673901 0.220 NM_012117
CBX5
chromobox homolog 5
chr7_+_89840999 0.219 NM_001244944
NM_001244945
NM_152999
NM_001040665
NM_001244946
STEAP2




STEAP family member 2, metalloreductase




chr3_+_159557649 0.219 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr8_-_18871163 0.211 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chrX_-_33146543 0.210 NM_004010
NM_004009
DMD

dystrophin

chr12_-_108714438 0.208 NM_001142345
CMKLR1
chemokine-like receptor 1
chrX_-_33229428 0.203 NM_004006
DMD
dystrophin
chr3_+_150321065 0.203 NM_016275
SELT
selenoprotein T
chr3_+_138067444 0.201 NM_001085049
NM_001252093
MRAS

muscle RAS oncogene homolog

chr7_-_37956515 0.197 NM_003014
SFRP4
secreted frizzled-related protein 4
chr1_-_6321034 0.193 NM_207370
GPR153
G protein-coupled receptor 153
chr2_+_148602569 0.191 NM_001616
ACVR2A
activin A receptor, type IIA
chr1_+_244214552 0.191 NM_205768
ZNF238
zinc finger protein 238
chrX_-_32430370 0.191 NM_004011
NM_004012
DMD

dystrophin

chr19_-_23578226 0.182 NM_003430
ZNF91
zinc finger protein 91
chrX_-_31526414 0.182 NM_004014
DMD
dystrophin
chr17_-_34417386 0.182 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr7_-_47621741 0.180 NM_022748
TNS3
tensin 3
chr8_-_18666295 0.179 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chrX_-_32173585 0.179 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr1_+_33116748 0.178 NM_001135255
NM_005610
NM_001135256
RBBP4


retinoblastoma binding protein 4


chr14_-_75078669 0.178 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr6_+_14117857 0.176 NM_001040280
NM_004233
CD83

CD83 molecule

chr16_+_8768403 0.174 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr17_+_70117154 0.173 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr7_-_129592794 0.172 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H

chr17_+_16945766 0.172 NM_015134
NM_201274
MPRIP

myosin phosphatase Rho interacting protein

chr6_+_106959729 0.170 NM_001624
AIM1
absent in melanoma 1
chr4_-_99579540 0.167 NM_005723
TSPAN5
tetraspanin 5
chr11_+_94822937 0.167 NM_015036
ENDOD1
endonuclease domain containing 1
chr1_+_244216506 0.165 NM_006352
ZNF238
zinc finger protein 238
chr5_+_169064238 0.165 NM_004946
DOCK2
dedicator of cytokinesis 2
chr12_-_108733075 0.163 NM_001142343
NM_001142344
NM_004072
CMKLR1


chemokine-like receptor 1


chr5_-_172756505 0.160 NM_003714
STC2
stanniocalcin 2
chr4_-_40859081 0.156 NM_001166051
NM_001166052
NM_001166053
NM_001166054
APBB2



amyloid beta (A4) precursor protein-binding, family B, member 2



chrX_+_12993224 0.156 NM_021109
TMSB4X
thymosin beta 4, X-linked
chr9_+_20658307 0.156 NM_017794
KIAA1797
KIAA1797
chr1_-_207095198 0.154 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr10_+_88428167 0.153 NM_001171610
LDB3
LIM domain binding 3
chr18_-_28622624 0.152 NM_001941
NM_024423
DSC3

desmocollin 3

chr10_-_105677986 0.149 NM_024928
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr17_-_43394326 0.148 NM_003954
MAP3K14
mitogen-activated protein kinase kinase kinase 14
chr7_-_129592711 0.147 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr1_+_99127146 0.144 NM_015976
NM_152238
SNX7

sorting nexin 7

chr10_-_116444374 0.144 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr20_-_43977023 0.142 NM_002999
SDC4
syndecan 4
chr12_+_3186520 0.141 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr10_+_103825123 0.140 NM_024747
HPS6
Hermansky-Pudlak syndrome 6
chr1_-_9884549 0.140 NM_001009566
NM_014944
CLSTN1

calsyntenin 1

chr17_+_2207219 0.140 NM_021947
SRR
serine racemase
chr21_+_44394634 0.139 NM_004571
PKNOX1
PBX/knotted 1 homeobox 1
chr10_-_116418056 0.139 NM_002313
ABLIM1
actin binding LIM protein 1
chr10_-_123356158 0.139 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr22_+_45064323 0.137 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr8_-_105601234 0.136 NM_001135703
NM_013437
LRP12

low density lipoprotein receptor-related protein 12

chr5_+_140797243 0.135 NM_018927
PCDHGB7
protocadherin gamma subfamily B, 7
chr16_+_8814567 0.135 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr13_-_36705513 0.135 NM_004734
DCLK1
doublecortin-like kinase 1
chr6_+_139456240 0.134 NM_016217
HECA
headcase homolog (Drosophila)
chr16_+_8806825 0.134 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr16_+_3115312 0.133 NM_001012631
NM_001012633
NM_001012718
NM_004221
IL32



interleukin 32



chr16_+_3115611 0.131 NM_001012635
IL32
interleukin 32
chr19_+_50380681 0.131 NM_001168222
NM_024682
TBC1D17

TBC1 domain family, member 17

chr4_-_41216455 0.131 NM_001166050
NM_004307
NM_173075
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr16_+_3115641 0.130 NM_001012632
NM_001012636
IL32

interleukin 32

chr1_-_170043608 0.130 NM_001204514
NM_001204516
NM_014970
KIFAP3


kinesin-associated protein 3


chr8_-_28243941 0.129 NM_018660
ZNF395
zinc finger protein 395
chr5_+_140864626 0.129 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr16_+_3115638 0.129 NM_001012634
IL32
interleukin 32
chr2_+_237993954 0.128 NM_006710
NM_198189
COPS8

COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)

chr2_-_169103886 0.127 NM_013233
STK39
serine threonine kinase 39
chr5_-_142065991 0.126 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr15_-_34681891 0.124 NM_181077
GOLGA8A
GOLGA8B
golgin A8 family, member A
golgin A8 family, member B
chr5_-_58571916 0.124 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_-_78083109 0.124 NM_004863
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr22_+_45098046 0.123 NM_181333
PRR5
proline rich 5 (renal)
chr19_+_16435632 0.122 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr5_-_142065586 0.121 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr16_+_67880784 0.120 NM_005796
NUTF2
nuclear transport factor 2
chr5_+_140810126 0.120 NM_003735
NM_032094
PCDHGA12

protocadherin gamma subfamily A, 12

chr10_-_116286661 0.120 NM_006720
ABLIM1
actin binding LIM protein 1
chr13_+_53029494 0.119 NM_001098525
NM_018204
CKAP2

cytoskeleton associated protein 2

chr4_+_68424444 0.119 NM_012108
STAP1
signal transducing adaptor family member 1
chr10_+_97471535 0.118 NM_001098175
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr1_+_169075869 0.117 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr7_-_87856282 0.116 NM_198901
SRI
sorcin
chr5_+_140749830 0.116 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr5_-_59189620 0.114 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_12695851 0.113 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chrX_-_33357725 0.113 NM_000109
DMD
dystrophin
chr2_+_36583369 0.113 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr4_-_103245468 0.112 NM_001135148
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr13_-_50510410 0.109 NM_001127482
NM_020456
SPRYD7

SPRY domain containing 7

chr7_-_87849366 0.108 NM_003130
SRI
sorcin
chr5_+_140868721 0.108 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr15_+_100106132 0.105 NM_001130926
NM_001130927
NM_001171894
NM_005587
MEF2A



myocyte enhancer factor 2A



chr17_-_7578810 0.105 NM_001126115
NM_001126116
NM_001126117
TP53


tumor protein p53


chr1_+_65613771 0.105 NM_013410
AK4
adenylate kinase 4
chr3_-_197476567 0.104 NM_001145642
KIAA0226
KIAA0226
chr1_+_84609941 0.104 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_140739589 0.103 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr13_+_77566043 0.103 NM_006493
CLN5
ceroid-lipofuscinosis, neuronal 5
chr10_+_97515408 0.103 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr2_+_54785453 0.102 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr1_-_170038055 0.102 NM_001204517
KIFAP3
kinesin-associated protein 3
chr17_-_7590731 0.101 NM_000546
NM_001126112
NM_001126113
NM_001126114
TP53



tumor protein p53



chr5_-_79286793 0.101 NM_001010891
NM_001167741
MTX3

metaxin 3

chr5_+_140753480 0.101 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr5_+_155753755 0.100 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr20_-_52687303 0.100 NM_003657
BCAS1
breast carcinoma amplified sequence 1
chr4_-_103266577 0.099 NM_001135146
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr18_+_61637262 0.098 NM_001031848
NM_002640
NM_198833
SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chr11_-_17191287 0.098 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr10_+_31608097 0.098 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr9_-_19786886 0.097 NM_001193288
NM_020344
SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chr8_-_74791098 0.097 NM_001001481
NM_018299
UBE2W

ubiquitin-conjugating enzyme E2W (putative)

chr6_+_25962978 0.096 NM_006355
TRIM38
tripartite motif containing 38
chr1_+_174844655 0.096 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr2_+_74056095 0.096 NM_006463
NM_213622
STAMBP

STAM binding protein

chr9_+_132962871 0.095 NM_001128826
NCS1
neuronal calcium sensor 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.