Motif ID: PAX6.p2

Z-value: 0.325


Transcription factors associated with PAX6.p2:

Gene SymbolEntrez IDGene Name
PAX6 5080 paired box 6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PAX6chr11_-_31832855-0.175.3e-01Click!


Activity profile for motif PAX6.p2.

activity profile for motif PAX6.p2


Sorted Z-values histogram for motif PAX6.p2

Sorted Z-values for motif PAX6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_61420276 0.744 NM_001040147
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_-_58343308 0.584 NM_004811
LPXN
leupaxin
chr16_+_72088507 0.427 NM_001126102
NM_005143
HP

haptoglobin

chrX_-_13835213 0.356 GPM6B
glycoprotein M6B
chr16_+_72097124 0.307 NM_020995
HPR
haptoglobin-related protein
chrX_-_13835187 0.275 GPM6B
glycoprotein M6B
chrX_-_130423387 0.272 NM_001170961
NM_001170962
NM_001555
NM_205833
IGSF1



immunoglobulin superfamily, member 1



chr3_+_111717585 0.248 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr7_-_73123431 0.240 STX1A
syntaxin 1A (brain)
chrX_-_13835012 0.233 GPM6B
glycoprotein M6B
chr21_+_39644428 0.230 NM_170737
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chrX_-_130423199 0.224 IGSF1
immunoglobulin superfamily, member 1
chr2_+_62934030 0.196 NM_001142614
EHBP1
EH domain binding protein 1
chr6_-_46703429 0.174 NM_001168357
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chrX_-_13835313 0.131 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr10_-_82049178 0.131 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr8_-_62602285 0.129 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr6_-_42162693 0.127 NM_002098
GUCA1B
guanylate cyclase activator 1B (retina)
chr6_-_10412606 0.124 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr3_+_133495925 0.114 TF
transferrin
chr9_+_124048396 0.111 GSN
gelsolin
chr4_+_100495972 0.107 MTTP
microsomal triglyceride transfer protein
chr12_+_56915587 0.106 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr11_+_844445 0.103 NM_001025237
TSPAN4
tetraspanin 4
chr11_+_117947726 0.100 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr5_-_142077508 0.096 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chr11_+_117947785 0.096 TMPRSS4
transmembrane protease, serine 4
chr15_-_50405512 0.096 ATP8B4
ATPase, class I, type 8B, member 4
chr11_+_19372270 0.090 NM_001111018
NAV2
neuron navigator 2
chr4_+_88896801 0.090 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr16_+_82068958 0.083 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr21_+_39628869 0.079 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr11_+_14926542 0.068 CALCB
calcitonin-related polypeptide beta
chr16_+_82068910 0.068 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_82068830 0.064 NM_002153
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr6_+_167704802 0.062 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr6_-_64029847 0.060 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr1_+_150480584 0.059 ECM1
extracellular matrix protein 1
chr19_+_7968820 0.051 MAP2K7
mitogen-activated protein kinase kinase 7
chr1_-_108786663 0.049 NM_001143989
NBPF4
NBPF6
neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6
chr1_-_12908141 0.049 NM_001146181
HNRNPCL1
LOC649330
heterogeneous nuclear ribonucleoprotein C-like 1
heterogeneous nuclear ribonucleoprotein C-like
chr4_-_10686314 0.048 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr5_+_140254930 0.043 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr12_+_18414473 0.043 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr1_-_31345361 0.035 SDC3
syndecan 3
chr3_-_194188967 0.034 NM_024524
ATP13A3
ATPase type 13A3
chr6_-_136788012 0.032 NM_001198615
MAP7
microtubule-associated protein 7
chr4_+_113970784 0.032 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr3_+_119500930 0.030 NR1I2
nuclear receptor subfamily 1, group I, member 2
chr17_-_34756980 0.030 NM_001123392
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3H
chrX_-_131573638 0.030 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr2_-_162931051 0.029 NM_001935
DPP4
dipeptidyl-peptidase 4
chr19_-_14910947 0.029 NM_198944
OR7C1
olfactory receptor, family 7, subfamily C, member 1
chr9_-_95166827 0.028 NM_014057
NM_033014
OGN

osteoglycin

chr4_+_187148624 0.028 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr11_-_117747331 0.027 FXYD6
FXYD domain containing ion transport regulator 6
chr20_+_9288446 0.027 NM_000933
PLCB4
phospholipase C, beta 4
chr17_-_36348585 0.026 NM_001123391
NM_032258
TBC1D3C
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3
TBC1 domain family, member 3F
chrX_+_148769902 0.026 NM_001011544
MAGEA11
melanoma antigen family A, 11
chr1_+_209878135 0.025 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr12_+_21168629 0.024 NM_001009562
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr5_+_140734767 0.023 NM_018917
NM_032053
PCDHGA4

protocadherin gamma subfamily A, 4

chr1_+_150480486 0.023 NM_001202858
NM_004425
NM_022664
ECM1


extracellular matrix protein 1


chrX_-_65259839 0.023 NM_001100431
NM_001184830
NM_001184831
NM_007268
VSIG4



V-set and immunoglobulin domain containing 4



chr3_+_49506079 0.022 NM_001177643
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr3_-_14583587 0.022 NM_001080423
GRIP2
glutamate receptor interacting protein 2
chr17_-_34503914 0.022 NM_001001417
TBC1D3B
TBC1D3C
TBC1D3G
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
chr8_-_87755880 0.022 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chrY_-_27198250 0.022 NM_001002760
NM_001002761
NM_004678
BPY2B
BPY2C
BPY2
basic charge, Y-linked, 2B
basic charge, Y-linked, 2C
basic charge, Y-linked, 2
chr17_+_36283959 0.021 NM_001123391
NM_032258
TBC1D3C
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr7_+_80267782 0.021 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr5_+_55147206 0.018 NM_001242637
NM_001242638
NM_139017
IL31RA


interleukin 31 receptor A


chr19_-_54327428 0.018 NM_144687
NLRP12
NLR family, pyrin domain containing 12
chr1_-_153044083 0.018 NM_001017418
SPRR2B
small proline-rich protein 2B
chrY_+_25130409 0.017 NM_001002760
NM_001002761
NM_004678
BPY2B
BPY2C
BPY2
basic charge, Y-linked, 2B
basic charge, Y-linked, 2C
basic charge, Y-linked, 2
chrY_+_26764150 0.017 NM_001002760
NM_001002761
NM_004678
BPY2B
BPY2C
BPY2
basic charge, Y-linked, 2B
basic charge, Y-linked, 2C
basic charge, Y-linked, 2
chr12_-_45269340 0.017 NM_001145109
NELL2
NEL-like 2 (chicken)
chrX_+_50653734 0.016 NM_005448
BMP15
bone morphogenetic protein 15
chr5_-_142815076 0.016 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr17_-_34591958 0.015 NM_001001418
TBC1D3C
TBC1D3G
TBC1 domain family, member 3C
TBC1 domain family, member 3G
chr12_-_57504088 0.015 NM_001178079
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr15_-_85197502 0.015 WDR73
WD repeat domain 73
chr5_+_143191725 0.015 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr1_+_147374945 0.013 NM_005267
GJA8
gap junction protein, alpha 8, 50kDa
chr15_-_85197512 0.012 NM_032856
WDR73
WD repeat domain 73
chr19_-_14992166 0.012 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr1_+_158901336 0.012 NM_152501
NM_198928
NM_198929
NM_198930
PYHIN1



pyrin and HIN domain family, member 1



chr10_+_129845806 0.012 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr20_-_45927496 0.011 ZMYND8
zinc finger, MYND-type containing 8
chr3_+_108015392 0.011 HHLA2
HERV-H LTR-associating 2
chr19_+_15852200 0.010 NM_013938
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr16_+_53479685 0.010 RBL2
retinoblastoma-like 2 (p130)
chr14_+_29241989 0.010 C14orf23
chromosome 14 open reading frame 23
chr6_-_131291480 0.009 NM_001199389
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_+_159409511 0.009 NM_012351
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr16_-_51184507 0.009 NM_001127892
SALL1
sal-like 1 (Drosophila)
chr1_+_114522029 0.009 NM_020190
OLFML3
olfactomedin-like 3
chr3_+_119501556 0.009 NM_022002
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr4_+_71226477 0.009 NM_012390
SMR3B
SMR3A
submaxillary gland androgen regulated protein 3B
submaxillary gland androgen regulated protein 3A
chr21_-_31588242 0.008 NM_199328
CLDN8
claudin 8
chr9_-_95244750 0.008 NM_001193335
NM_017680
ASPN

asporin

chr22_+_31366662 0.008


chr4_-_68749698 0.007 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chr8_+_7705401 0.007 NM_058203
NM_001081552
SPAG11B
SPAG11A
sperm associated antigen 11B
sperm associated antigen 11A
chr18_-_47806361 0.007 NM_001204151
MBD1
methyl-CpG binding domain protein 1
chr7_+_45067232 0.007 NM_001029835
CCM2
cerebral cavernous malformation 2
chr8_-_21771111 0.006 NM_003974
DOK2
docking protein 2, 56kDa
chr20_+_4702499 0.006 NM_012409
PRND
prion protein 2 (dublet)
chr7_+_110731061 0.006 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr12_+_10460416 0.006 NM_002262
NM_007334
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr13_+_24844846 0.005 SPATA13
spermatogenesis associated 13
chr15_+_45544427 0.005 NM_004212
SLC28A2
solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chr10_+_102222797 0.005 NM_003393
WNT8B
wingless-type MMTV integration site family, member 8B
chr3_+_136649316 0.005 NM_001190796
NCK1
NCK adaptor protein 1
chr2_-_200213802 0.005 SATB2
SATB homeobox 2
chr1_-_13611532 0.004 NM_001012276
PRAMEF8
PRAMEF7
PRAME family member 8
PRAME family member 7
chr6_-_75994631 0.004 NM_001143958
NM_018247
TMEM30A

transmembrane protein 30A

chr8_-_59412695 0.004 NM_000780
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr5_+_175223519 0.003 NM_006650
CPLX2
complexin 2
chr17_+_9745847 0.003 GLP2R
glucagon-like peptide 2 receptor
chr11_+_76883823 0.002 MYO7A
myosin VIIA
chr4_+_71263598 0.002 NM_021225
PROL1
proline rich, lacrimal 1
chr1_-_182922504 0.002 NM_030933
SHCBP1L
SHC SH2-domain binding protein 1-like
chr6_-_131321868 0.001 NM_001252660
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr20_-_44144263 0.001 NM_006652
SPINT3
serine peptidase inhibitor, Kunitz type, 3
chrX_+_144908927 0.001 NM_004709
CXorf1
chromosome X open reading frame 1
chr12_-_2986299 0.000 NM_001243088
NM_001243089
NM_021953
NM_202002
NM_202003
FOXM1




forkhead box M1





Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.