Motif ID: PBX1.p2

Z-value: 0.256


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PBX1chr1_+_164818083-0.116.9e-01Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_29137776 0.485 NM_001005735
NM_007194
NM_145862
CHEK2


checkpoint kinase 2


chr13_-_46679143 0.465 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr15_-_37391893 0.328 MEIS2
Meis homeobox 2
chr2_-_200322699 0.327 NM_001172509
SATB2
SATB homeobox 2
chr4_-_69886112 0.274 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr6_+_26199712 0.273 NM_003522
HIST1H2BF
histone cluster 1, H2bf
chr15_-_37393364 0.270 NM_001220482
NM_002399
MEIS2

Meis homeobox 2

chr1_-_182360889 0.264 GLUL
glutamate-ammonia ligase
chr6_+_26124372 0.243 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr14_+_24584321 0.242 DCAF11
DDB1 and CUL4 associated factor 11
chr1_-_149399159 0.235 NM_001024599
HIST2H2BF
histone cluster 2, H2bf
chr20_-_45976626 0.227 ZMYND8
zinc finger, MYND-type containing 8
chr11_+_95523608 0.207 NM_001243776
NM_001243777
NM_014679
CEP57


centrosomal protein 57kDa


chr9_-_116840545 0.205 AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_116840604 0.201 AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_116840460 0.200 AMBP
alpha-1-microglobulin/bikunin precursor
chr2_-_174829951 0.196 SP3
Sp3 transcription factor
chr9_-_99382073 0.179 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr4_+_69681709 0.173 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr9_-_116840551 0.173 AMBP
alpha-1-microglobulin/bikunin precursor
chr6_-_26199439 0.172 NM_021065
NM_003530
HIST1H2AD
HIST1H3D
histone cluster 1, H2ad
histone cluster 1, H3d
chr3_-_148804122 0.168 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr6_-_26124130 0.164 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr14_+_23938883 0.164 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr11_+_95523809 0.163 CEP57
centrosomal protein 57kDa
chr8_+_107738239 0.156 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr5_+_162864571 0.151 NM_004060
NM_199246
CCNG1

cyclin G1

chr14_+_24584009 0.150 DCAF11
DDB1 and CUL4 associated factor 11
chr4_-_70080448 0.149 NM_001073
UGT2B11
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B11
UDP glucuronosyltransferase 2 family, polypeptide B10
chr6_+_27114860 0.148 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr6_+_111195986 0.148 NM_001634
NM_001033059
AMD1

adenosylmethionine decarboxylase 1

chr12_+_81471796 0.144 NM_024560
ACSS3
acyl-CoA synthetase short-chain family member 3
chr5_-_149535420 0.143 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr2_-_21225640 0.142 APOB
apolipoprotein B (including Ag(x) antigen)
chr1_-_19229016 0.140 NM_003748
NM_170726
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr1_+_15990300 0.139


chr8_-_38008332 0.139 NM_000349
STAR
steroidogenic acute regulatory protein
chr1_+_149858466 0.138 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr17_-_46703613 0.136 NM_024017
HOXB9
homeobox B9
chr2_-_88427535 0.136 NM_001443
FABP1
fatty acid binding protein 1, liver
chr4_-_174255454 0.133 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr6_+_135502477 0.131 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr12_+_12869818 0.130 NM_004064
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr3_+_193853930 0.128 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr10_-_72142344 0.128 NM_018205
NM_018239
LRRC20

leucine rich repeat containing 20

chr14_+_24583979 0.125 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr1_-_182360400 0.125 NM_001033056
GLUL
glutamate-ammonia ligase
chr6_-_31830593 0.121 NM_000434
NEU1
sialidase 1 (lysosomal sialidase)
chr6_-_27114577 0.119 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr2_+_44395983 0.118 NM_001033556
NM_001033557
NM_002706
NM_177968
NM_177969
PPM1B




protein phosphatase, Mg2+/Mn2+ dependent, 1B




chr3_+_120627026 0.115 NM_014980
STXBP5L
syntaxin binding protein 5-like
chr10_+_102123420 0.115


chr14_+_24583905 0.114 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr14_+_23938902 0.112 NGDN
neuroguidin, EIF4E binding protein
chr2_-_47134945 0.111 MCFD2
multiple coagulation factor deficiency 2
chr1_-_149859465 0.111 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr10_+_5005685 0.110 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr6_-_31830551 0.110 NEU1
sialidase 1 (lysosomal sialidase)
chrX_+_9431314 0.109 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr7_-_140179133 0.109 MKRN1
makorin ring finger protein 1
chr11_+_57365026 0.109 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr16_-_58663734 0.109 CNOT1
CCR4-NOT transcription complex, subunit 1
chr1_-_149783910 0.108 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr7_+_107110501 0.108 NM_005295
GPR22
G protein-coupled receptor 22
chr12_+_64803741 0.108 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr4_+_70146216 0.107 NM_001207004
NM_053039
UGT2B28

UDP glucuronosyltransferase 2 family, polypeptide B28

chr3_+_193853937 0.106 HES1
hairy and enhancer of split 1, (Drosophila)
chr3_-_121553836 0.106 IQCB1
IQ motif containing B1
chr12_-_57914287 0.106 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr7_-_140179224 0.106 MKRN1
makorin ring finger protein 1
chr5_-_89705477 0.101 NM_004365
CETN3
centrin, EF-hand protein, 3
chr5_+_43603312 0.099 NNT
nicotinamide nucleotide transhydrogenase
chr19_-_49955025 0.098 NM_017916
PIH1D1
PIH1 domain containing 1
chr4_-_155511838 0.097 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr5_-_149535138 0.095 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr11_+_22689653 0.095 NM_177553
GAS2
growth arrest-specific 2
chr5_+_43603287 0.095 NNT
nicotinamide nucleotide transhydrogenase
chr16_+_19078958 0.094 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr1_-_149858114 0.094 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr5_+_44808967 0.094 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr5_+_43603216 0.094 NM_182977
NNT
nicotinamide nucleotide transhydrogenase
chr12_+_51442081 0.094 NM_001243689
NM_015416
LETMD1

LETM1 domain containing 1

chr2_+_62932786 0.093 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr18_-_59854288 0.093 NM_012327
NM_176787
PIGN

phosphatidylinositol glycan anchor biosynthesis, class N

chr16_+_19078916 0.092 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_-_148939784 0.092 NM_000096
CP
ceruloplasmin (ferroxidase)
chr16_-_58663739 0.092 NM_016284
NM_206999
CNOT1

CCR4-NOT transcription complex, subunit 1

chr16_-_70323343 0.091 AARS
alanyl-tRNA synthetase
chr18_-_59854179 0.091 PIGN
phosphatidylinositol glycan anchor biosynthesis, class N
chr7_+_26400503 0.090 NM_001199837
SNX10
sorting nexin 10
chr5_+_43602738 0.090 NM_012343
NNT
nicotinamide nucleotide transhydrogenase
chr15_+_59908724 0.089 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr9_-_116840673 0.089 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr6_+_31707724 0.089 NM_002441
NM_025259
NM_172165
NM_172166
MSH5-C6orf26
MSH5



MSH5-C6orf26 readthrough (non-protein coding)
mutS homolog 5 (E. coli)



chr8_-_108510094 0.088 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr1_+_60280462 0.086 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr17_+_45973515 0.085 NM_003110
SP2
Sp2 transcription factor
chr7_+_149571029 0.084 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr16_-_70323407 0.084 NM_001605
AARS
alanyl-tRNA synthetase
chr22_+_40297183 0.082 GRAP2
GRB2-related adaptor protein 2
chr3_-_121553907 0.082 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr19_+_39881950 0.081 NM_017592
MED29
mediator complex subunit 29
chrX_+_70503469 0.081 NONO
non-POU domain containing, octamer-binding
chrX_-_130423199 0.080 IGSF1
immunoglobulin superfamily, member 1
chr6_+_27775898 0.080 NM_003509
HIST1H2AI
HIST1H2AM
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H2am
histone cluster 1, H3f
chr19_+_14640403 0.078 TECR
trans-2,3-enoyl-CoA reductase
chr7_-_148725764 0.078 NM_004911
PDIA4
protein disulfide isomerase family A, member 4
chr19_+_39882018 0.078 MED29
mediator complex subunit 29
chr17_+_80416606 0.076 NARF
nuclear prelamin A recognition factor
chr19_+_14640406 0.075 TECR
trans-2,3-enoyl-CoA reductase
chr6_+_31783280 0.075 NM_005345
HSPA1A
heat shock 70kDa protein 1A
chrX_+_70503496 0.075 NONO
non-POU domain containing, octamer-binding
chr6_+_31783314 0.074 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr2_-_219134795 0.072 AAMP
angio-associated, migratory cell protein
chr6_-_30684851 0.072 MDC1
mediator of DNA-damage checkpoint 1
chr2_-_219134846 0.071 AAMP
angio-associated, migratory cell protein
chr13_+_97928414 0.071 MBNL2
muscleblind-like 2 (Drosophila)
chr16_+_2653350 0.070 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chr6_+_135502521 0.070 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_26104103 0.070 NM_003542
HIST2H4B
HIST1H4C
histone cluster 2, H4b
histone cluster 1, H4c
chrX_+_123234462 0.070 STAG2
stromal antigen 2
chr5_-_149535309 0.068 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr17_+_80416530 0.068 NM_001083608
NM_012336
NM_031968
NARF


nuclear prelamin A recognition factor


chr10_+_69869249 0.068 NM_032578
MYPN
myopalladin
chr12_-_122231554 0.068 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr2_+_238875586 0.066 NM_080678
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr6_-_42713822 0.066 TBCC
tubulin folding cofactor C
chr5_-_171881421 0.066 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr17_+_56315786 0.066 NM_001160102
NM_006151
LPO

lactoperoxidase

chr7_+_100136784 0.065 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr9_-_124989755 0.065 NM_001242334
LHX6
LIM homeobox 6
chr15_-_37391596 0.064 NM_172316
MEIS2
Meis homeobox 2
chr17_-_38821286 0.063 NM_152349
KRT222
keratin 222
chr8_+_48873533 0.063 MCM4
minichromosome maintenance complex component 4
chr17_-_79650755 0.063 NM_001040025
ARL16
ADP-ribosylation factor-like 16
chr1_+_24840800 0.062 NM_001251980
NM_001251982
NM_001251985
RCAN3


RCAN family member 3


chr6_+_26217145 0.062 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr10_+_5005453 0.062 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr2_-_219134865 0.060 NM_001087
AAMP
angio-associated, migratory cell protein
chr5_+_145826866 0.060 NM_001040006
NM_006706
TCERG1

transcription elongation regulator 1

chr4_+_6271558 0.060 NM_001145853
NM_006005
WFS1

Wolfram syndrome 1 (wolframin)

chr15_-_77712436 0.060 NM_024776
PEAK1
NKF3 kinase family member
chr3_+_157827849 0.059 NM_016625
RSRC1
arginine/serine-rich coiled-coil 1
chr1_-_115323262 0.059 NM_001102396
NM_025073
SIKE1

suppressor of IKBKE 1

chr6_+_26273143 0.058 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr16_+_19079220 0.058 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr5_+_140018998 0.058 NM_018502
TMCO6
transmembrane and coiled-coil domains 6
chr7_+_39017608 0.057 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr20_-_54967221 0.057 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr19_+_14640363 0.057 NM_138501
TECR
trans-2,3-enoyl-CoA reductase
chr1_+_6845381 0.057 NM_001195563
NM_001242701
NM_015215
CAMTA1


calmodulin binding transcription activator 1


chr7_-_148725500 0.057 PDIA4
protein disulfide isomerase family A, member 4
chr1_+_111415721 0.057 NM_000560
CD53
CD53 molecule
chr6_-_26271588 0.055 NM_003534
HIST1H3G
histone cluster 1, H3g
chr11_+_34460421 0.054 NM_001752
CAT
catalase
chr1_-_182354649 0.054 GLUL
glutamate-ammonia ligase
chr16_+_82068830 0.054 NM_002153
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr4_+_88896868 0.053 SPP1
secreted phosphoprotein 1
chr7_-_7680048 0.053 RPA3
replication protein A3, 14kDa
chr14_-_74551073 0.053 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr10_-_101190201 0.053 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chrX_-_15353634 0.053 PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chrX_-_15353675 0.052 NM_002641
NM_020473
PIGA

phosphatidylinositol glycan anchor biosynthesis, class A

chr1_-_200379165 0.052 NM_012482
ZNF281
zinc finger protein 281
chr1_-_59147727 0.052


chrX_+_70503512 0.052 NONO
non-POU domain containing, octamer-binding
chr12_+_6603291 0.051 NM_014865
NCAPD2
non-SMC condensin I complex, subunit D2
chr4_+_6271588 0.051 WFS1
Wolfram syndrome 1 (wolframin)
chr19_-_39340609 0.051 NM_001533
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr19_-_51869632 0.051 NM_001985
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr2_+_163200582 0.051 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chrX_+_70503534 0.050 NONO
non-POU domain containing, octamer-binding
chr16_+_3493605 0.050 NM_001083601
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr1_-_160990862 0.050 F11R
F11 receptor
chr2_-_183731279 0.050 NM_001463
FRZB
frizzled-related protein
chr1_-_57431620 0.049 NM_000066
C8B
complement component 8, beta polypeptide
chr19_-_14247400 0.048 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr13_+_97928196 0.048 MBNL2
muscleblind-like 2 (Drosophila)
chr1_+_110881944 0.048 NM_001201545
NM_022768
RBM15

RNA binding motif protein 15

chr4_+_129730772 0.048 NM_024900
NM_199320
PHF17

PHD finger protein 17

chr12_+_28410132 0.048 NM_018318
CCDC91
coiled-coil domain containing 91
chr19_+_14640413 0.048 TECR
trans-2,3-enoyl-CoA reductase
chr3_+_52811601 0.048 NM_002215
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr14_-_36789794 0.047 NM_001144891
NM_016586
MBIP

MAP3K12 binding inhibitory protein 1

chr19_-_14247267 0.047 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr1_-_3713048 0.047 NM_020710
LRRC47
leucine rich repeat containing 47
chr4_+_6271605 0.047 WFS1
Wolfram syndrome 1 (wolframin)
chr7_-_143599163 0.047 NM_014719
NM_001206938
FAM115A

family with sequence similarity 115, member A

chr4_+_88896801 0.047 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr14_+_23790671 0.047 PABPN1
poly(A) binding protein, nuclear 1
chr19_+_50529276 0.046 ZNF473
zinc finger protein 473
chr19_+_50529211 0.046 NM_001006656
NM_015428
ZNF473

zinc finger protein 473

chr6_-_42713837 0.046 NM_003192
TBCC
tubulin folding cofactor C
chr10_-_115933884 0.046 C10orf118
chromosome 10 open reading frame 118
chr4_-_140005344 0.045 ELF2
E74-like factor 2 (ets domain transcription factor)
chr14_+_58765209 0.045 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr18_-_52625278 0.045 NM_001143829
CCDC68
coiled-coil domain containing 68
chr4_+_88896838 0.045 SPP1
secreted phosphoprotein 1
chr15_-_64673569 0.045 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr6_+_149721494 0.045 NM_001002255
SUMO4
SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.